The invention relates to a health-care mushroom juice for preventing and / or improving cardiovascular and cerebrovascular diseases and a preparation method thereof. The raw material components include: mushroom juice, trehalose, shiitake mushrooms, black fungus, onion, celery, broccoli, corn, Scallion, garlic, ginseng, salvia, astragalus, sophora japonica, peach kernel, cinnamon, radix radix, schisandra, hawthorn, jujube seed, jujube, angelica and ginger. In the present invention, by using vegetables and traditional Chinese medicine decoction pieces with the same origin of food and medicine with special regulating effects as raw materials, the health-care mushroom juice prepared has reasonable formula, rich nutrition and delicious taste; and it also has the effect of regulating blood fat and blood pressure, and plays a role The effect of preventing or improving cardiovascular and cerebrovascular diseases; the preparation method is simple, the production cost is low, and the operability is strong.