The invention provides a liver-protecting lychee juice and a preparation method thereof, and belongs to the field of food processing, wherein the raw materials comprise: lychee, jasmine, pomelo peel,honey, licorice root, Primula obconica Hance, Chinese wolfberry, Zizania latifolia, Myricaria bracteata Royle, Patience Dock Root, Veronicastrum species, Stevia rebaudiana, Selaginella uncinata and citric acid. The invention further provides a preparation method of the liver-protecting lychee juice, wherein the preparation method comprises: preparing a jasmine-lychee juice, preparing a pomelo peelChinese herbal juice, preparing a mixed juice, and preparing a liver-protecting lychee juice. According to the present invention, the liver-protecting lychee juice is prepared by using lychee, jasmine, pomelo peel and various Chinese herbal ingredients as the main raw materials, has fragrant, sweet, refreshing and mellow taste, has the nutrition of fruits and vegetables, and further has effects of liver protection, kidney benefiting, qi regulating, stomach nourishing and body strengthening through the co-action of the raw materials.