The invention relates to the technical field of construction engineering, and discloses a safety protection fence for construction engineering construction. The safety protection fence for construction engineering construction comprises a base frame, connecting blocks, supports, lighting lamps, a reinforcement plate, a bottom plate, water absorption blocks, a protection net, a cylinder, fixing screws, a reinforcement column, a counterweight, fixing frames, transverse frames, auxiliary screws and sleeve blocks, and the left and right sides of the base frame are fixedly connected with the connecting blocks. According to the safety protection fence for construction engineering construction and a use method thereof, the strength and weight of the fence are increased by additionally arranging the reinforcement plate and the bottom plate outside the base frame, both ventilation and protection are achieved by using the protection net, the exchange of rain or liquid inside and outside a construction site is reduced by using the water absorption blocks to reduce the mutual effect of the inside and the outside of the construction site, the counterweight and the reinforcement column provide larger supporting force for the fence and reduce the harm of wind blowing and collision, the sleeve blocks and the transverse frames are connected with the fixing frames to reinforce connection of thecomponents, force bearing is more uniform, the purpose of higher stability is achieved, and trouble caused by toppling of the protection fence is reduced.