The invention discloses a factory processing and sterilization preservation process of instant seasoned lobster, which comprises the following steps of selecting raw materials, cleaning, boiling, removing heads of the selected lobster, half drying the lobster, packaging the half-dried lobster in bags, sterilizing and preserving the packed lobster. The process is remarkably characterized by comprising the steps of: cleaning intestine, seasoning and boiling, half drying in microwave and sterilizing by irradiation, wherein the factory processing and sterilization preservation process specifically comprises the following steps of: selecting qualified, fresh and alive lobsters, flushing, brushing, soaking for removing dirt, rinsing, and then boiling the clean lobsters with an amount of water and seasoners, heating the boiled lobsters through microwave for steaming till the lobsters are half dried, packing the certain amount of the lobsters in a soft-package plastic bag, vacuuming and sealing, irradiating by gamma-rays generated by isotope cobalt 60 for sterilizing, and refrigerating in a refrigerator at a temperature under 5 DEG C. The instant seasoned lobster prepared by the factory production process disclosed by the invention has the advantages of delicious taste, abundant nutrition, environment protection, safety and convenience for carriage.