The invention discloses a method for preparing industrial
fructose with isomeric glucose by adopting a chemical
catalysis method. The method comprises the following steps that 1, a glucose water solution is prepared,
borax and
sodium hydroxide are sequentially added into the glucose water solution, then
magnesium-based
solid base is added, and reaction is performed in the
inert atmosphere; 2, reaction is completed, a
solid base catalyst is recovered through
solid-liquid separation, liquid is fed into an electroosmosis
system, and glucose and a
fructose complex are separated to obtain a
fructose borate complex solution; 3, the fructose borate complex solution flows through
boron specific resin to remove the
borax and the
sodium hydroxide, and a pure fructose product is obtained. By combining homogeneous-phase base
catalysis and non-homogeneous-phase base
catalysis, the method is suitable for higher
substrate concentration, also improves the
isomerization rate and fructose selectivity, utilizes the difference of the fructose complex and glucose to achieve their simple and efficient separation, provides possibility for large-scale development of fuel and chemicals based on an industrial fructose platform and has a good application prospect.