Method for preparing industrial fructose with isomeric glucose by adopting chemical catalysis method

Abstract

The invention discloses a method for preparing industrial fructose with isomeric glucose by adopting a chemical catalysis method. The method comprises the following steps that 1, a glucose water solution is prepared, borax and sodium hydroxide are sequentially added into the glucose water solution, then magnesium-based solid base is added, and reaction is performed in the inert atmosphere; 2, reaction is completed, a solid base catalyst is recovered through solid-liquid separation, liquid is fed into an electroosmosis system, and glucose and a fructose complex are separated to obtain a fructose borate complex solution; 3, the fructose borate complex solution flows through boron specific resin to remove the borax and the sodium hydroxide, and a pure fructose product is obtained. By combining homogeneous-phase base catalysis and non-homogeneous-phase base catalysis, the method is suitable for higher substrate concentration, also improves the isomerization rate and fructose selectivity, utilizes the difference of the fructose complex and glucose to achieve their simple and efficient separation, provides possibility for large-scale development of fuel and chemicals based on an industrial fructose platform and has a good application prospect.

Description

technical field [0001] The invention relates to fructose preparation technology, in particular to a method for chemically catalyzing the isomerization of glucose into fructose. Background technique [0002] Compared with glucose, fructose as a sugar platform molecule is easier to prepare some high value-added chemicals (such as 5-hydroxymethylfurfural, levulinic acid, etc.). Given that glucose is widely present in biomass, developing a cost-effective fructose-glucose isomerization pathway to produce industrial fructose can promote a higher level of utilization of biomass resources. The so-called industrial fructose is relative to edible fructose, the production of industrial fructose can appropriately allow the use of catalysts and raw materials that are banned in the food industry. At present, fructose is widely used as a sweetener in the food field, and most of it is obtained by enzymatic isomerization of glucose. However, the enzymatic method is limited by the high cost ...

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a method for preparing industrial fructose from glucose isomerization by chemical catalysis, and solve the problems of poor selectivity, low substrate concentration, and difficulty in separation and purification of catalyzed glucose isomerization into fructose by existing chemical methods