51 results about "Urethral infection" patented technology

The invention discloses a medicine-carrying nano antibacterial super-smooth coating for marine organisms. The medicine-carrying nano antibacterial super-smooth coating comprises a medicine-carrying nano antibacterial slow-release coating and a hydrophilic coating, wherein the medicine-carrying nano antibacterial slow-release coating comprises medicine-carrying nano particles and antibacterial substances; the medicine-carrying nano particles have effects of restraining and preventing bacteria and sustaining release, and have bacteria-inhibiting effects on escherichia coli, staphylococcus aureus, candida albicans and the like which cause urinary tract infection easily; the antibacterial substances further can improve the antibacterial effects of the medicine-carrying nano antibacterial slow-release coating, so that the medicine-carrying nano antibacterial slow-release coating achieves lasting and stable antibacterial effects; after contacting water, substances of the hydrophilic layer can quickly form a lubricating film, so that the conduit surface is sufficiently and efficiently lubricated, and the conduit is conveniently and quickly implanted; after the conduit is implanted, the hydrophilic polymer is dissolved into water to play synergetic bacteriostatic action with the medicine-carrying nano particles and the antibacterial substances, and the loaded bacteria-restraining components are slowly released to finally achieve the lasting and stable antibacterial effects.

The invention discloses a compound bergamot oil nano-emulsion composition, which is characterized in that: the granularity of the nano-emulsion is 1nm to 100nm, and comprises the following substances by weight mass: 23 to 35 percent of surface active agent, 0.3 to 8 percent of cosurfacant, 1.5 to 10 percent of bergamot oil, 0.5 to 5.5 percent of patchouli, 0.4 to 4.5 percent of tea tree oil, 0.3 to 2.2 percent of pennyroyal and distilled water, wherein the sum of the mass percentage of the ingredients is 100 percent. The compound bergamot oil nano-emulsion composition is broad-spectrum antimicrobic, has good treatment effect on eczema, psoriasis, herpes, dermatitis, blain, wound, acne, urinary infection and the like, the permeability is strong, the stability is good, content of active ingredients is high, transdermal absorption effect is remarkable, action time is durable, the preparation method is simple and is easy to popularize and use, and the medicine has vast application prospect on the medical market.

The invention relates to an antibiotic substituted by nitrogen heterocyclic ring, and a preparation method and the application thereof, pertaining to the antibiotic medicament of a human body, and discloses the structural formula (I) of 7-(Alpha-(N, N-bis (1-methylethyl)-thiourea) acetamido)-3-(((2, 5-dihydro-6-hydroxy-2-methyl-5-oxo-1, 2, 4-triazine-3-base)sulfo)methyl)-cephalosporin polyhydroxyalkanoate sodium salt and sylvite, and a manufacturing method and the application thereof. The antibiotic has good antibacterial activity, can treat diseases caused by hypersensitive gram positive bacteria and gram negative bacteria, bloodpoisoning, alimentary infection, urinary tract infection, has long half-life of plasma and little toxicity and can reduce times for taking medicaments every day and treatment fees. The compound has good stability and is stored at normal temperature; the manufacturing method is simple; a product obtained by the manufacturing method has high purity and meets medical requirements.

The invention discloses a new medicine for curing urethral infection and the preparing method thereof, prepared of raw materials such as Membranous Milkvetch Root, Pink Herb, Fuling, Common Yan Rhizome, Prepared Common Monkshood Daughter Root, and Rhizoma Smilacis Glabrae processed by different physical or chemical methods according to their different physical or chemical properties into acceptable forms in clinical practice. Its formula is peculiar, and it is used for curing urethral infection in clinical practice, having remarkable curative effect.

A Chinese medicine in the form of particles for treating urethral infection is prepared from common sage herb, plantain herb, threeflower bluebeard, and to kyo violet herb.

The invention discloses a novel method for screening anti-bacterial adhesion inhibitors and preparation of anti-bacterial adhesion oral liquid. The novel method disclosed by the invention comprises the following steps of: immersing a glass slide with a specific shape into a liquid culture medium to carry out bacterial adhesion; adding a screened sample into the culture medium; and analyzing and judging anti-bacterial adhesion medicinal effect through a microscopic image. The anti-bacterial adhesion oral liquid disclosed by the invention is prepared from the raw materials including pilea notata, honeysuckle and poria cocos through extracting, liquid matching, fermenting, freezing and centrifugal processes and has the pharmaceutical effects of resisting bacterial adhesion, intestinal infection, urinary tract infection and cold.

The invention relates to a kit for detecting presence of pathogen pseudomonas aeruginosa in patient samples such as clinical bacterial pneumonia, corneal ulcer, urinary tract infection, septicemia and the like and samples such as cosmetics, environmental monitoring objects and the like, in particular to a kit for early and quickly diagnosing pseudomonas aeruginosa infection by a real-time fluorescence quantitative polymerase chain reaction technique.

The invention discloses a urogenital tract infection pathogen multiple detection kit and application thereof. Specifically, the invention develops a fluorescent quantitative PCR (Polymerase Chain Reaction) kit for detecting 12 clinical common urethral infection germs. The optimized primer and probe provided by the invention have more excellent combination of 12 groups of PCR primers and probes, have excellent stability, and do not interfere with each other in a PCR reaction process, so that the optimized primer and probe can be used for a multiplex fluorescent quantitative PCR method.

A method for detecting inflammation in the urinary tract or urethra of a patient, especially urethritis, comprises a) contacting leucocytes obtained from a urine sample provided by the patient with a luminescence reagent which emits light on reaction with an oxidant; b) adding an activator to the mixture of leucocytes and luminescence reagent; c) continuously monitoring and / or measuring light emitted by the luminescence reagent over a predetermined time period commencing before and ending after the addition of the activator. The light emission is indicative of the presence or absence of inflammation in the urinary tract or urethra of the patient. The urine sample is preferably a sample of first pass urine. The method makes possible a diagnosis especially of urethritis and, in particular, urethral infections selected from Chlamydia trachomatis and Neisseria gonorrhoeae, which can be carried out quickly without invasive procedures. A diagnostic kit for carrying out the method, comprising a luminescence reagent which emits light on reaction with an oxidant, an activator and a library of standard signature light emission curves is also disclosed.

Catheter-adapted briefs operative to stabilize an indwelling urethra catheter in a position of alignment with the natural orientation of the male urethral orifice to minimize catheter discomfort, prevent urine leakage, tissue damage, and reduce the frequency of urinary track infection.

The invention provides a specific primer and a probe for detecting cronobacter sakazakii. A sequence of the probe is 5'-CGTTCAGGAGAGCCACCG-3'; a sequence of the specific primer is the following sequences or the complementary chain sequences of the following sequences: an upstream primer sequence is 5'-GAACTGACCGATGACGTA-3'; a downstream primer sequence is 5'-GTCTCATTAAACGGCTCG-3'. The invention further provides a corresponding real-time fluorescence quantitative PCR (Polymerase Chain Reaction) kit. The invention provides the specific primer and the probe, can fulfill the aim of accurately andquantitatively detecting content of cronobacter sakazakii in a to-be-detected specimen by extracting genome DNA (deoxyribonucleic acid) of the cronobacter sakazakii and combining a real-time fluorescence quantitative PCR detection technology, has high sensitivity and high specificity, and has important significance on judging the content of active bacteria of the cronobacter sakazakii and even performing subsequent research on urinary tract infection.

The invention relates to the field of medicines and particularly relates to a composition and an application of the composition as well as a medicine, a food, a beverage or a health product comprising the composition. The composition is prepared from the following raw materials in parts by weight: 30-100 parts of cranberry original juice, 6-20 parts of mulberry original juice and 4-12 parts of raspberry (red raspberry) original juice. According to the composition which is compounded, the effects of the cranberries, mulberries and raspberries (red raspberries) for treating urinary tract infection are interactively enhanced, thereby showing a good compounding effect. Animal experiments verify that the composition has a good preventing and treating effect on ascending experimental urinary tract infection of mice.

The invention discloses a preparation method of magnesium boride nanoparticles. According to liquid phase plasma technology, the magnesium boride nanoparticles are synthesized by reducing MgCl2 with borane in triethylphenylammonium bis (trifluoromethanesulfonyl) imine ionic liquid at room temperature. Compared with commercial magnesium boride, the prepared magnesium boride nanoparticles are largerin specific surface area and stronger in antibacterial effect. Compared with amikacin and vertilmicin sulfate, the magnesium boride nanoparticles prepared by the invention show stronger antibacterialactivity on enterobacter cloacae. Through the excellent antibacterial property of the enterobacter cloacae, the wide application of magnesium boride in the clinical treatment fields of hospital infected bacterial infectious diseases, such as skin soft tissue infection, urinary tract infection, respiratory tract infection and septicemia is expected to expand.

The invention discloses a non-coating antibacterial urinary catheter. The urinary catheter comprises a body and a fixing part; the body is provided with a urinary catheterization cavity for urinary catheterization and a urinary catheterization port communicating with the urinary catheterization cavity; the fixing part is arranged at one end of the body; and a urinary catheterization hole is arranged on the body away from the urinary catheterization port, and can communicate with the urinary catheterization cavity and the inner wall of the urethra; By applying the non-coating antibacterial urinary catheter, urine discharged by a patient washes the wall of the urethra through the liquid guide holes, antibiotic drugs are not needed for assisting in antibiosis, the normal mechanical effect andthe normal urinary system defense mechanism of the urethra are played, and even if bacteria enter the bladder, 99.9% of bacteria and para-gland secreta can be discharged out of the body through one-time urination. Meanwhile, the normal urinary system defense mechanism (including the defense function of meta-acid PH urine, ammonia, urea, lysozyme, organic matter and other antibacterial active substances contained in the meta-acid PH urine) is exerted. Therefore, bacterial colonization is reduced, and the occurrence probability of urethral infection is greatly reduced.

The invention provides a prescription for treating urinary tract infection. The prescription comprises, by weight, 60g of polygonum aviculare, 30g of plantago asiatica, 15g of lonicera japonica and 3g of radix glycyrrhizae. The prescription for treating the urinary tract infection has the advantages that the prescription is applicable to patients with the urinary tract infection caused by various causes, and the prescription is capable of increasing the acidity of urine to allow various bacteria inducing the urinary tract infection to be not able to survive, comprehensively and effectively killing pathogenic bacteria, eliminating in-vivo viruses and thoroughly curing the urinary tract infection and free of side effects.

A Chinese medicine in the form of tablet or capsule for treating urethral infection is prepared from turmeric, amur barberry bark, phyllanthus emblica and tribulus fruit through decocting and concentrating.

The invention relates to medical appliances and particularly relates to a multifunctional dual-sacculus urethral catheter. The multifunctional dual-sacculus urethral catheter comprises a catheter part, a sacculus part and a topping-up part. The multifunctional dual-sacculus urethral catheter mainly comprises a urethral catheter main pipe, a urine inlet, a bladder sacculus, a urinary tract sacculus, a urinary tract sacculus drain hole, a bladder sacculus topping-up one-way valve, a urinary tract sacculus topping-up one-way valve and a urine discharge opening. The urinary tract sacculus drain hole is formed in the edge of the end part of the urinary tract sacculus. According to the multifunctional dual-sacculus urethral catheter, besides having functions of an ordinary urethral catheter, through injecting normal saline or other medicated liquid into the urinary tract sacculus, a urinary tract can be cleaned and lubricated, or a drug can be continuously supplied into the urinary tract fora long time to prevent and treat urinary-tract infection, and the risk of serious complications such as urinary-tract infection of patients with long-term urethral catheter reserving is lowered. Themultifunctional dual-sacculus urethral catheter can also be applied to dilation treatment on urethral stricture and direct-administration treatment on prostate disorders. The multifunctional dual-sacculus urethral catheter is simple in structure, low in cost, safe and convenient in use and convenient in large-batch production. The multifunctional dual-sacculus urethral catheter is applicable to all patients needing to reserve a urethral catheter for 24 hours or more.

A Chinese medicine ''Niaoganning'' is prepared from 5 Chinese-medicinal materials including lygodium spores stem, longtube groundivy herb, Chinese brake herb, Tokyo violet herb, etc. Its preparing process is also disclosed.

The instant invention relates to the prevention of recurrence of urethral stricture after a conventional treatment. Compositions applicable to the prevention of recurrence of urethral stricture after as conventional treatment, including a pharmaceutically effective amount of halofuginone, are disclosed. Urethral stricture, as common disease, appears secondary to urethritis, urethral infection, urethral inflammation, urethral instrumentation, urethral catheterization, urethral trauma, urethral surgery and all types of urethral lesions. Conventional treatments by internal urethrotomy, urethral dilatation or surgical urethroplasty are available and can cure urethral stricture, but with a relatively high rate of recurrence of the stricture. Halofuginone can prevent the recurrence of urethral stricture after conventional treatment via internal urethrotomy, urethral dilatation or surgical urethroplasty.

An indwelling catheter and a catheter assembly belong to the field of catheters in clinical urology. The indwelling catheter includes a catheter body, the end of the catheter body is provided with a catheter hole and an indwelling bladder that can expand and contract, the indwelling bladder is provided with a cavity, and the front end of the catheter body is provided with a catheter The catheter interface connected with the hole and the capsule interface connected with the indwelling capsule body, the outer wall of the catheter body is provided with a groove, the catheter body is provided with a cleaning channel connected with the groove, and the catheter body is far away from the catheter hole One end is provided with a cleaning port communicating with the cleaning channel. The indwelling catheter can effectively wash and disinfect the urethra of patients with the indwelling catheter, and can prevent, reduce and treat urinary tract infection. The present invention also provides a urinary catheter assembly with the above-mentioned indwelling catheter.

Prevention of recurrence of urethral stricture after a conventional treatment. Composition applicable to the prevention of recurrence of urethral stricture after a conventional treatment, including a pharmaceutically effective amount of halofuginone. Urethral stricture, a common disease, appears secondary to urethritis, urethral infection, urethral inflammation, urethral instrumentation, urethral catheterization, urethral trauma, urethral surgery and all types of urethral lesions. Conventional treatments by internal urethrotomy, urethral dilation or surgical urethroplasty are available and can cure urethral stricture, but with a relatively high rate of recurrence of the stricture. Halofuginone can prevent the recurrence of urethral stricture after a conventional treatment via internal urethrotomy, urethral dilation or surgical urethroplasty.

A method for detecting inflammation in the urinary tract or urethra of a patient, especially urethritis, comprises a) contacting leucocytes obtained from a urine sample provided by the patient with a luminescence reagent which emits light on reaction with an oxidant; b) adding an activator to the mixture of leucocytes and luminescence reagent; c) continuously monitoring and / or measuring light emitted by the luminescence reagent over a predetermined time period commencing before and ending after the addition of the activator. The light emission is indicative of the presence or absence of inflammation in the urinary tract or urethra of the patient. The urine sample is preferably a sample of first pass urine. The method makes possible a diagnosis especially of urethritis and, in particular, urethral infections selected from Chlamydia trachomatis and Neisseria gonorrhoeae, which can be carried out quickly without invasive procedures. A diagnostic kit for carrying out the method, comprising a luminescence reagent which emits light on reaction with an oxidant, an activator and a library of standard signature light emission curves is also disclosed.

The invention relates to polymer particles combined with hyaluronic acid molecules or hyaluronate and a preparation method thereof, the polymer particles are composed of poly(lactic acid-co-glycolic acid) (PLGA) polymers, poly(lactic acid-co -glycolic acid)-polyethylene glycol-poly(lactic acid-co-glycolic acid) (PLGA-PEG-PLGA) copolymer, or mixtures thereof. The invention also relates to injectable cosmetic or pharmaceutical compositions containing such polymer particles, processes for the preparation of such compositions and their use as medicines (in particular for the prophylaxis and / or Treatment of: musculoskeletal disorders, traumatic conditions of the skin and skin diseases, oral symptoms, dryness of the vaginal mucous membranes and urinary tract infections or cystitis, dry eye membranes and eye infections, and obesity), and their role in preventing skin aging and / or repairing the dermis Use in tissue (mesotherapy). More specifically, the compositions of the present invention may be aimed at replenishing joint fluid, especially synovial fluid, reestablishing the rheological and physiological conditions of pathological joints (e.g. arthritic joints), or effectively remodeling, moisturizing and protecting the skin. Treats and repairs the epidermis.

The invention relates to a Chinese medicament for treating urinary tract infection, which is prepared from the following raw material medicaments by a conventional method: 25 to 35g of pyrrosiaLeaf, 30 to 34g of spreading hedyotis herb, 6 to 10g of puff-ball, 6 to 8g of scorpion, 10 to 16g of rhizoma bolbostemmae, 20 to 30g of plantain seed, 10 to 16g of radix achyranthis bidentatae, 15 to 25g ofrhizoma dioscoreae septemlobae, 15 to 25g of grassleaf sweelflag rhizome, 15 to 25g of Sichuan amur corktree bark, 18 to 26g of motherwort herb, 25 to 35g of campanumaea pilosula and 15 to 25g of astragalus. The Chinese medicament has the characteristics of simple preparation, low cost, wide medicinal sources, convenient use, capability of inactivating viruses, clearing heat and detoxicating, strengthening body resistance and eliminating evil, and treating both symptoms and root causes, no toxic or side effect, good curative effect, quick response, and 93.55 percent of clinical effective rate.

The invention relates to an antibiotic substituted by nitrogen heterocyclic ring, and a preparation method and the application thereof, pertaining to the antibiotic medicament of a human body, and discloses the structural formula (I) of 7-(Alpha-(N, N-bis (1-methylethyl)-thiourea) acetamido)-3-(((2, 5-dihydro-6-hydroxy-2-methyl-5-oxo-1, 2, 4-triazine-3-base)sulfo)methyl)-cephalosporin polyhydroxyalkanoate sodium salt and sylvite, and a manufacturing method and the application thereof. The antibiotic has good antibacterial activity, can treat diseases caused by hypersensitive gram positive bacteria and gram negative bacteria, bloodpoisoning, alimentary infection, urinary tract infection, has long half-life of plasma and little toxicity and can reduce times for taking medicaments every day and treatment fees. The compound has good stability and is stored at normal temperature; the manufacturing method is simple; a product obtained by the manufacturing method has high purity and meets medical requirements.

The invention relates to a catheterization device and a catheterization external member. The catheterization device comprises a first structure part placed in a bladder of a patient and a second structure part kept in the urethra of the patient, wherein a catheterization cavity in the first structure part communicates with a catheterization passage in the second structure part; the second structure part is elastically opened in the urethra of the patient, and is fixed in the urethra; the first structure part is also provided with a plurality of catheterization openings communicating with the catheterization cavity, an on-off mechanism is arranged at each catheterization opening, the on-off mechanisms are opened when the external pressure of the first structure part reaches set pressure andenable the catheterization cavity to communicate with the bladder of the patient, and the on-off mechanisms are closed when the external pressure of the first structure part is smaller than the set pressure and enable the catheterization cavity not to communicate with the bladder of the patient. The catheterization device disclosed by the invention is simple and compact in structure, is convenient to mount, use and disassemble, can be kept in the body of the patient for a long term, can greatly reduce the infection rick of the urethra and can also effectively reduce the cost.

The present invention relates to topical spray compositions comprising chitosan and the method for preparation thereof. The topical spray compositions comprising chitosan are used for the treating burn wounds, wounds resulting from chemical burns, wounds from physical trauma, neuropathic ulcers, pressure sores, diabetic ulcers. Further, the spray compositions composition is used for treating gynaecological diseases, urogenital infections (vaginal bacteriosis, urinary tract infection and vaginitis) with good effect, safe, natural, and good biocompatibility by restoring and / or maintaining the pH of vagina. More specifically the present invention relates to topical spray compositions comprising chitosan and carbonic acid and the method for preparation thereof.

The invention discloses traditional Chinese medicine for treating overactive bladder and recurrent urethral infection. The traditional Chinese medicine comprises the following raw materials in parts by weight: 40-60 parts of yam, 20-30 parts of astragalus membranaceus, 20-30 parts of radix codonopsis, 20-30 parts of fried bighead atractylodes rhizome, 15-25 parts of poria, 10-20 parts of rhizoma alismati and 15-20 parts of rhizoma smilacis glabrae. The traditional Chinese medicine for treating overactive bladder and recurrent urethral infection provided by the invention is prepared from the traditional Chinese medicine, radically treats symptoms induced by overactive bladder and recurrent urethral infection and is free of toxic side effect in a treatment process.