87 results about "Rheumatologic Disorder" patented technology

The invention discloses medicinal composition for remedying fracture, luxation and soft tissue injury and a preparation method thereof. The composition comprises 46 components of raw medicines such asangelica, safflower, Chinese flowering quince, achyranthes root, dahurian angelica root, eucommia ulmoies, herba schizonepetae, ledebouriella root and atractylodes rhizome, etc. The medicinal composition of the invention has the advantages of blood circulation promotion by removing blood stasis, reunion of the bone, expelling wind and removing damness, dispersing cold and relieving pain, and hasobvious effect to fracture remedy and soft tissue injury, simultaneously, the invention has good curative effect to the remedy of various paralysis arthralgia such as muscular rheumatism, rheumatoid disease, spondylitis spondylitis, senile arthritis, and neck, shoulder and arm pain and lumbago and scelalgia.

The present invention relates to a urea derivative of the formula (1)wherein each symbol is as described in the specification, a pharmaceutically acceptable salt thereof and pharmaceutical use thereof. The compound of the present invention has a C5a receptor antagonistic action and is useful as an agent for the prophylaxis or treatment of diseases or syndromes due to inflammation caused by C5a [e.g., autoimmune diseases such as rheumatism, systemic lupus erythematosus and the like, sepsis, adult respiratory distress syndrome, chronic obstructive pulmonary disease, allergic diseases such as asthma and the like, atherosclerosis, cardiac infarction, brain infarction, psoriasis, Alzheimer's disease and serious organ injury (e.g., pneumonia, nephritis, hepatitis, pancreatitis and the like) due to activation of leukocytes caused by ischemia, trauma, burn, surgical invasion and the like]. In addition, it is useful as an agent for the prophylaxis or treatment of infectious diseases caused by bacteria or virus that invades via a C5a receptor.

The invention discloses a immune imprinting regent box of the rheumatism self antibody which includes the print film in the reacting slot, the enzyme linked regent, the color regent A liquid, the color regent B liquid, the stop liquid, the condense washing solution and the standard band. Firstly, the ENA is divided by the SDS-polyacrylamide gel electrophoresis according to the molecular weight, then transfers it into the print membrane by the print technology which includes the ENA arrayed by the molecular weight; if the detected blood serum has the self antibody, it will disappear the color band by adding the enzyme linked and the color regent after combining with the according antigen. So it can detect that if the serum has the antibody of Sm, U1RNP,ssA,ssB,Scl-70,Jo-1,Ro60,Rib to diagnose and identify the rheumatism.

The invention discloses a traditional Chinese medicine preparation for treating gout and a production method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from the following traditional Chinese medicine raw materials in parts by weight: 130-180 parts of polygonum cuspidatum, 120-170 parts of desmodium styracifolium, 90-140 parts of dandelion, 110-150 parts of lalang grass rhizome, 60-120 parts of cocculus orbiculatus, 90-130 parts of the root of kudzu vine, 60-110 parts of pyrrosia lingua, 70-120 parts of semen coicis, 80-130 parts of plantain herb, 60-110 parts of rhizoma alismatis, 60-110 parts of achyranthes aspera and 60-110 parts of radix paeoniae alba. The compound composition with the function of preventing gout is scientific in formula, is based on experience formulas applied to clinical treatment for years, has the functions of clearing away heat and toxic materials, expelling stasis to relieve pain, promoting blood circulation to remove meridian obstruction and the like, and is stable in clinical curative effect, appropriate in dosage and convenient to use when being used for treating various gout and rheumatism diseases.

The invention provides a product for treating systemic lupus erythematosus and rheumatism and a preparation method thereof, and belongs to the field of Chinese patent medicine and pharmacy technology thereof. The invention is characterized in that the product is obtained from common submerged fermentation of a water extract of the following traditional Chinese medicines and a morel mother strain: 20-40 parts of radix clematis, 20-40 parts of Ligusticum wallichii, 20-40 parts of madder, 20-40 parts of late silkworm excrement, 20-40 parts of red adzuki beans, 20-40 parts of angelica, 20-40 parts of cinnamon and 20-40 parts of semen allii tuberosi. In some embodiments, a fetus cervi powder is added in the submerged fermentation, so that the product is rich in plant polypeptides from traditional Chinese medicines. Fungus polysaccharide of the morel, animal polysaccharide from the fetus cervi powder and coordination compounds of the three polysaccharides have substantial effects on integrally enhancing immunity of the patients. The product provided by the invention can simultaneously treat principal and subordinate symptoms, and have no toxic or side effect, and fast effectiveness.

The invention relates to a girald daphne bark adhesive paste. The adhesive paste is prepared from the following raw materials in parts by weight: 5-10 parts of a traditional Chinese medicine extract, 1-5 parts of an adhesive, 0.1-0.5 part of a filling agent, 0.1-0.5 part of a transdermal absorption enhancer, 5-15 parts of a moisturizing agent, 0.1-0.5 part of a crosslinking agent, 0.1-0.5 part of a crosslinking regulator, 0.1-0.5 part of a thickening agent and 15-20 parts of distilled water. Meanwhile, the invention also discloses a preparation method of the girald daphne bark adhesive paste. The girald daphne bark adhesive paste disclosed by the invention has the effects of resisting inflammation and easing pain, and can be applied to the treatment on rheumatism, rheumatoid diseases and swellings and pains caused by various reasons.

Indazole compounds that modulate and / or inhibit the ophthalmic diseases and the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and / or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating ophthalmic diseases and cancer and other disease states associated with unwanted angiogenesis and / or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.

Nanostructures, compositions and methods for treating vesicle-related or exosome-related conditions are provided. In some cases, the nanostructures and / or compositions may be used to treat cancers, neurological disorders, rheumatologic disorders, viral disorders or other diseases or conditions at least in part by regulating vesicle uptake. Methods of analyzing, imaging and modulating vesicles and cellular vesicles processes are also provided.

The invention discloses application and a detection method of an LINC02085 gene, and belongs to the technical field of molecular biology of rheumatism. According to the invention, a specific PCR primer is designed and synthesized according to the extracted total RNA sequence, and an Rt-qPCR technology is utilized to find that the expression of LINC02085 in peripheral blood mononuclear cells of a rheumatoid arthritis (RA) patient is significantly increased, which proves that the LINC02085 can be applied to the preparation of a preparation for auxiliary diagnosis, treatment or prognosis evaluation of rheumatoid arthritis. The pcDNA3.1-LINC02085 sequence for specific overexpression of the gene and the si-LINC02085 sequence for small interference of the gene are designed and synthesized at thesame time, proliferation of synovial fibroblasts (FLS) and inflammatory response of FLS induced by TNF-alpha can be remarkably inhibited by regulating and controlling a PI3K / AKT signal channel, and the gene can become a molecular targeted therapy tool for RA.

The invention discloses a bee venom permeating agent, a preparation method of the bee venom permeating agent, a preparation and an application. Raw materials of the bee venom comprise alcohol, wasp bee venom powder, old working bee of live wasp and picadura. After the steps of the bee venom original fluid preparation, the worker bee material preparation, the mother liquid preparation and the preparation, the bee venom permeating agent is obtained. The bee venom permeating agent can be directly smeared on the pain areas caused by rheumatism, scapulohumeral periarthritis and arthritis. The bee venom permeating agent rapidly permeates through the histocyte, the blood capillary and other areas of the pain areas through the skin clearance. The effect is direct, the curative effect is rapid, and the efficacy of the bee venom especially the wasp bee venom is fully utilized. Accordingly, the current problems of the low efficacy of the wine steeping with the old worker bee and non-drinkers are thoroughly solved.

The invention relates to a method of treating a patient suffering from peripheral vascular disease, peripheral neuropathies, or autonomic neuropathies by administering a cGMP PDE5 inhibitor such as sildenafil. The method is particularly applicable to patients suffering from diabetic foot ulcers, Raynaud's Phenomenon, CREST Syndrome, erythromatosis, rheumatoid diseases, diabetic retinopathies and onychiomycosis. According to the present invention, a cGMP PDE5 inhibitor may be administered as a prophylactic to patients predisposed to develop a peripheral vascular disease, peripheral neuropathy or autonomic neuropathy.

The invention relates to a physiotherapy device for treating rheumatism disclosed by the present invention comprises a bed board, a rotating frame, a support frame, a rotating plate and a distribution box, the bed board, the support frame and the rotating plate form a bed body, electric slide rail devices are arranged on two side surfaces of the bed board along the axis direction, and a physiotherapy mechanism is arranged above the electric slide rail devices. A leg massage device and a rotating device for supporting the rotating plate to rotate are arranged on the bottom surface of the supporting frame. According to the physiotherapy device for treating rheumatism, through the arrangement of a sliding frame and an electric sliding block, the resistance value of a sliding rheostat connected to an electric baking lamp can be adjusted, the electric baking temperature of the electric baking lamp is automatically adjusted, through the arrangement of a transmission mechanism, the irradiation angle can be automatically adjusted when the electric baking lamp is moved, through the arrangement of a fumigation box, the legs are fumigated, in addition, a first motor can be started during physical therapy, so that the first motor drives a massage cylinder to rotate through gear transmission, the legs are massaged, and the purposes of improving the physical therapy effect and accelerating recovery are achieved.

The present invention relates to an amide derivative of the formula (1), having a C5a receptor antagonistic actionwherein each symbol is as defined in the specification.The above-mentioned amide derivative, an optically active form thereof and a pharmaceutically acceptable salt thereof are promising as an agent for the treatment or prophylaxis of diseases or syndromes caused by inflammation caused by C5a [e.g., autoimmune diseases such as rheumatism, systemic lupus erythematosus and the like, sepsis, adult respiratory distress syndrome, chronic obstructive pulmonary disease, allergic diseases such as asthma and the like, atherosclerosis, cardiac infarction, brain infarction, psoriasis, Alzheimer's disease and serious organ injury (e.g., pneumonia, nephritis, hepatitis and pancreatitis and the like) due to activation of leukocytes caused by ischemia reperfusion, trauma, burn, surgical invasion and the like]. Moreover, they are useful as a therapeutic or prophylactic agent for the infectious diseases caused by bacteria and virus that invade via a C5a receptor.

The invention discloses an application of serum protein HFREP1 in diagnosis of a rheumatoid arthritis disease state. Disease states of rheumatoid arthritis disease activity scoring systems DAS28 and RA recommended according to European anti-rheumatism alliance are divided into an activity period and a remission period. However, the DAS28 scoring system is a set of subjective scoring system and hashigh requirements for experience of doctors. According to the invention, the serum protein HFREP1 has extremely high diagnostic value in the aspect of diagnosing and distinguishing the active periodand the remission period of rheumatoid arthritis, is high in diagnostic accuracy, is objective and easy to operate compared with the existing DAS28 scoring system, and can be used for preparing a diagnostic kit for diagnosing and distinguishing the active period and the remission period of rheumatoid arthritis.

The invention discloses traditional Chinese medicine foot bath powder for treating rheumatism and preparation and application method of the traditional Chinese medicine foot bath powder. The traditional Chinese medicine foot bath powder is prepared from the following components in parts by weight: 10-30 parts of radix angelicae pubescentis, 10-20 parts of divaricate saposhnikovia roots, 10-25 parts of sichuan lovage rhizome, 10-20 parts of rhizoma smilacis glabrae, 5-15 parts of radix achyranthis bidentatae, 3-15 parts of cortex acanthopanacis, 10-20 parts of cassia twig, 8-20 parts of caulis spatholobi, 5-10 parts of myrrh, 10-20 parts of asarum sieboldii, 10-20 parts of lycopodium clavatum, 5-10 parts of cattail pollenand 5-10 parts of gentiana macrophylla. With various natural Chinese herbal medicines as raw materials, the traditional Chinese medicine foot bath powder has the efficacies of expelling wind, drying dampness and activating meridians to stop pain, has a good curative effect or pain-relieving effect on rheumatism, and is safe, reliable and free of toxic and side effects.

The invention discloses Chinese herbal medicine powder for treating rheumatism and an administration method thereof, the Chinese herbal medicine powder is prepared by 12 Chinese herbal medicines, namely clematis root, long-noded pit viper, dragon's blood, ground beetle, east Asian tree fern rhizome, himalayan teasel root, fortune's drynaria rhizome, divaricate saposhnikovia root, garden balsam stem, doubleteeth pubescent angilica root, Indian buead and Chinese angelica, and glutinous rice congee is further added and uniformly mixed for administration. The Chinese herbal medicine powder can effectively treat various types of rheumatism, is precise and appropriate in combination and compatibility and can treat both manifestation and root cause of the disease; furthermore, the Chinese herbalmedicine powder belongs to pure traditional Chinese medicine agents, has few side effects and simultaneously has the advantages of rapid onset of action, short treatment course, high cure rate, simplicity and convenience in preparation, low treatment cost and the like.

The invention provides novel long-chain non-coding RNA of a RA marker and application of the novel long-chain non-coding RNA, belonging to the field of molecular biology of rheumatism. The novel long-chain non-coding RNA is AC123912.4, and the nucleotide sequence of the long-chain non-coding RNA is as shown in SEQ ID NO. 1. According to the sequence of the long-chain non-coding RNA, specific real-time quantitative PCR primers and probes are designed and synthesized, and a preparation for auxiliary diagnosis or curative effect prediction of RA is prepared. A real-time quantitative PCR preparation is utilized to detect the expression level of the long-chain non-coding RNA in an RA clinical case specimen, and it is found that the expression of the long-chain non-coding RNA in the RA is obviously up-regulated; and thus, the long-chain non-coding RNA is expected to be made into a preparation for auxiliary diagnosis or curative effect prediction of the RA.

The present invention discloses a traditional Chinese medicine preparation having anti-rheumatoid effect, and a production method thereof. The traditional Chinese medicine preparation comprises, by weight, 130-180 parts of caulis trachelospermi, 255-305 parts of polygonum cuspidatum, 220-260 parts of milkvetch root, 250-305 parts of treebine stem cavlis cissi, 120-170 parts of eucommia ulmoides, 190-240 parts of radix rehmanniae preparata, 150-200 parts of rhizoma cibotii, 165-220 parts of black ant, 250-305 parts of coix seed, 190-250 parts of climbing entada, and 85-135 parts of aristolochia fordiana hemsl. According to the present invention, the anti-rheumatoid effect compound composition has the scientific formula, is from the experience prescription applied in the Chinese medical science clinic for a plurality of years, has effects of heat clearing, detoxification, stasis eliminating, pain relieving, blood circulation promoting, meridian obstruction remove, and the like, is used for treating various rheumatic disorders, and further has characteristics of stable clinical efficacy, proper dose, and easy use.

The invention aims at providing a method for preparing functional soft capsules for treating rheumatoid diseases. The soft capsules for treating rheumatoid diseases have the advantages that patients can orally take conveniently, the effect is good and the cost is low. The invention provides a pharmaceutical preparation for treating rheumatoid arthritis, wherein the pharmaceutical preparation is prepared from medicaments, such as himalayan teasel root, centipedes, safflower, scorpion, radix cyathulae, licorice root, camphor, long-nosed pit viper, medlar, eucommia bark and the like. The pharmaceutical preparation provided by the invention per dose contains 200g of himalayan teasel root, 200g of safflower, 200g of radix cyathulae, 200g of licorice root, 200g of camphor, 200g of medlar, 200g of scorpion, 200g of eucommia bark, ten centipedes and two long-nosed pit vipers. The pharmaceutical preparation provided by the invention is prepared through preparing a high-concentration medicated liquid preparation from Chinese herbal medicine ingredients and then filling the high-concentration medicated liquid preparation into soft capsules or wax pills.

The invention relates to an externally applied medicine for treatment of rheumatism and rheumatoid diseases, and in particular relates to an externally applied powdery medicine has the effects of warming channel, expelling cold, dispersing blood stasis, dredging collaterals, relieving swelling and pain, dehumidifying and the like. The medicine is prepared from the following raw materials by weight: 7 parts of eucommia, 7 parts of achyranthes root, 4 parts of homalomena occulta, 4 parts of peach seed, 4 parts of safflower, 4 parts of drynaria baronii, 7 parts of hindu datura flower, 1 part of radix aconiti preparata, 4 parts of Chinese angelica and 2 parts of radix angelicae. A preparation method is as follows: picking and cleaning the ten medicinal materials of eucommia, achyranthes root, homalomena occulta, peach seed, safflower, drynaria baronii, hindu datura flower, radix aconiti preparata, Chinese angelica and radix angelicae, drying in the sun, separately grinding into fine powder, mixing evenly, quantitatively packaging with each bag filled with 50g for standby use; when in use, mixing honey and the medicine in a ratio of 1:1, mixing into paste, putting the paste on a 5cm *5cm gauze to be externally applied to pain points of patients, then using infrared ray for radiation for 30 minutes for one time in every day, wherein one period of treatment is 10 days. By clinical observation, the externally applied powdery medicine has the advantages of good treatment effects, high cure rate and less tendency to recurrence after treatment.

The invention discloses a medicinal liquor used for treating rheumatism. The medicinal liquor is prepared from, by weight, 25 to 30g of radix angelicae pubescentis, 25 to 30g of Herba Taxilli, 25 to 30 parts of cortex eucommiae, 25 to 30g of radix achyranthis bidentatae, 25 to 30g of Herba Asari, 25 to 30g of Radix Gentianae Macrophyllae, 25 to 30g of Poria cocos, 25 to 30g of cortex cinnamomi, 25 to 30g of radix saposhnikoviae, 25 to 30g of Ligusticum chuanxiong Hort., 25 to 30g of ginseng, 25 to 30g of radix glycyrrhizae, 25 to 30g of Angelica sinensis, 25 to 30g of Chinese herbaceous peony, 25 to 30g of dried rhizoma rehmanniae, 25 to 30g of mulberry, 25 to 30g of pawpaw, 25 to 30g of Sargentodoxa cuneata, 25 to 30g of cortex acanthopanacis, 25 to 30g of loofah sponge, 25 to 30g of Rhizoma Homalomenae, 25 to 30g of radix clematidis, 25 to 30g of Berchemia racemosa Sieb. et Zucc., 25 to 30g of Moghania philippinensis, 25 to 30g of Herba Lycopodii, 15 to 20g of radix aconite, 15 to 20g of radix aconiti kusnezoffii, 25 to 30g of Rhizoma seu Radix Notopterygii, and 5 to 10kg of pure grain white spirit. The medicinal liquor is low in cost, excellent in curative effect, and short in treatment period.

The invention discloses health-care liquor for dispelling wind, removing dampness, invigorating kidney and strengthening yang. The health-care liquor is prepared by soaking the following medicinal materials through 3-4L of sorghum white spirit: 35-50 grams of achyranthes aspera, 50-60 grams of eucommia ulmoides, 30-40 grams of lycium chinense, 40-60 grams of tetradium ruticarpum, 50-55 grams of rhizome drynariae and 25-30 grams of ramulus mori. A method for making the health-care liquor comprises the following steps of: soaking all the traditional Chinese medicinal materials which are taken according to the formula under hermetic condition in a proportion for 6-7 days at room temperature; then standing, filtering out medicine residues; and filling the medicine which is qualified by inspection into bottles so as to obtain the product. The practical use result of the health-care liquor shows that the medicine liquor has a good health care effect on patients suffering from rheumatism, rheumatoid diseases and scapulohumeral periarthritis and has a good heath care function for patients suffering from kidney deficiency and lumbago. The medicine liquor can be drunk by both adult males and adult females, and is particularly suitable for the middle-aged and aged people to drink.

The invention discloses an application of 1-(5-(3-((4-chlorobenzyl)amino)-2-hydroxypropoxy)-2-methyl-1-(p-tolyl)-1H-indol-3-yl) ethanone in treatment or prevention of inflammatory diseases. The compound is used for preventing and / or relieving and / or adjunctively treating and / or treating inflammatory diseases such as bronchitis, pneumonia, hepatitis, rhinitis, enterogastritis, gastritis, nephritis,dermatitis, prostatitis, vaginitis, rheumatism and the like. The 1-(5-(3-((4-chlorobenzyl)amino)-2-hydroxypropoxy)-2-methyl-1-(p-tolyl)-1H-indol-3-yl) ethanone has a specific inhibition effect on PI3K gamma and has an inhibition effect on inflammatory cell proliferation and chemotaxis. The compound can inhibit inflammatory response by inhibiting the PI3K gamma.

It is intended to identify rheumatoid arthritis susceptibility genes by a highly efficient, low-cost mapping method using microsatellites. In the present invention, novel rheumatoid arthritis susceptibility genes, that is, TNXB, NOTCH4, RAB6A, MPRL48, UCP2, and UCP3 genes, in the human genomic DNA sequence were identified by conducting case-control association analysis on rheumatoid arthritis by use of microsatellite polymorphic markers assigned at approximately 100-kb intervals to narrow down candidate regions and then conducting association analysis and linkage analysis with SNP as a marker.

The invention relates to the field of medicine, and particularly relates to a drug of a traditional Chinese medicine composition for treating rheumatism. The traditional Chinese medicine composition for treating rheumatism is characterized by consisting of the following raw medicines in parts by weight: 10-30 parts of radix aconiti, 30-60 parts of rhizoma ligustici chuanxiong, 20-50 parts of rhizoma curculiginis, 30-60 parts of cortex erythrinae, 40-70 parts of kadsura pepper stem, 30-60 parts of herba aristolochiae mollissimae, 20-50 parts of rhizoma homalomenae, 20-50 parts of garden balsam stem, 40-70 parts of semen cuscutae and 20-50 parts of herba lycopi. The traditional Chinese medicine composition provided by the invention completely focuses on the etiology and pathogenesis of rheumatism, is in scientific and reasonable compatibility of medicines, treats both symptoms and root causes, and realizes the functions of dispelling wind and eliminating dampness, warming and invigorating kidney yang, relieving swelling and pain and activating blood and dredging collaterals.

The invention relates to a traditional Chinese medicine composition for treating rheumatism, an ointment and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is capable of effectively solving the problems of poor effect and large toxic and side effects of the medicine for treating the rheumatism. According to the technical scheme, the traditional Chinese medicine composition comprises the following raw materials by weight: 13-17g of angelica sinensis, 9-11g of ligusticum wallichii, 9-11g of pseudo-ginseng, 9-11g of root of red-rooted salvia, 9-11g of eucommia ulmoides, 13-17g of parasitic loranthus, 9-11g of large-leaved gentian, 9-11g of radix angelicae pubescentis, 9-11g of notopterygium root, 13-17g of radix paeoniae alba, 13-17g of radices sileris, 9-11g of frankincense, 9-11g of myrrh, 9-11g of pawpaw, 4-6g of radix aconiti preparata and 4-6g of liquorice. The ointment of the traditional Chinese medicine composition disclosed by the invention is prepared from pure natural traditional Chinese medicines; various medicines are in organic fit and mutual support, are reasonable in compatibility; the raw materials are abundant; the method is simple; the local tissue nutrition metabolism is improved; tissue regeneration is promoted; the traditional Chinese medicine composition has analgesic and anti-inflammatory effects, is free of a toxic or side effect and easy to accept, is capable of preventing the pain of a patient, can be used for a long period of time, has good anti-inflammatory, analgesic and immune inhibition effects, is good in curative effect, and low in cost, and is a great innovation in medicines for treating rheumatism.

The invention discloses a traditional Chinese medicine rheumatoid pill for treating rheumatoid disease. The traditional Chinese medicine rheumatoid pill for treating rheumatoid disease is characterized by being prepared from the following components of wine-prepared rhizoma typhonii slices, rhizoma arisaematis praeparata, herba asari, radix gentianae macrophyllae, radix clematidis, wine-fried radix angelicae sinensis, liquorice root, fructus psoraleae, eupolyphaga sinensis, centipede, scorpio, radix saposhnikoviae, frankincense, myrrh, radix angelicae dahurioae, radix paeoniae alba, ramulus cinnamomi, fructus chaenomelis and semen strychni praeparata. The traditional Chinese medicine rheumatoid pill has the advantages that according to the characteristics of wind-cold damp pathogen, flowing into joints, Qi stagnation and blood stasis, and phlegm stagnation of rheumatoid, the traditional Chinese medicine rheumatoid pill is prepared; the effect of treating the rheumatoid is realized by dispelling cold and wind, excreting dampness and radiating heat, activating blood circulation and removing blood stasis, relieving pain, removing phlegm and removing stasis; the obtaining of raw materials is easy, the preparation is simple, any toxic or side effect is avoided, and the treatment effect is obvious.

The invention provides a medicine kit for treating rheumatism arthritis. The medicine kit is mainly prepared from the following raw materials in weight percent: 8-12% of caulis sinomenii, 8-12% of berba aristolochiae mollissimae, 8-12% of kadsura pepper stems, 8-12% of ligusticum wallichii, 8-12% of obscured homalomena rhizome, 8-12% of turmeric, 8-12% of root-bark of chinese hydrangeavine, 8-12% of Chuanlong yam, 8-12% of ledebouriella seseloides wolff and 8-12% of asiatic toddalia root. The medicine kit is simple to prepare; all the materials only need to be mixed at the ratios and are crushed into fine powder to prepare the medicine kit. The medicine kit is used by immersing so that drug properties directly enter focuses from pores, and the medicine kit has the effects of expelling wind and removing coldness, relaxing tendons and activating collaterals, activating blood, inducing menstruation to relieve menalgia and the like; the medicine kit is suitable for patients suffering from rheumatism arthritis and rheumatoid arthritis. The medicine kit is convenient to use; when the medicine kit is used, water is added to decoct, and the medicine kit is boiled for 10 minutes after the water is boiled up; after the temperature is cooled to be about 45 DEG C, feet can be immersed for half an hour and the medicine kit can be reheated and repeatedly used.

The invention provides a traditional Chinese medicine composition for treating rheumatoid arthritis. The traditional Chinese medicine composition is prepared from, by mass, 80-140 g of radix angelica sinensis, 40-80 g of caulis spatholobi, 40-80 g of rhizome polygoni cuspidate, 20-60 g of girald daphne bark, 20-60 g of pendulous monkshood root, 20-60 g of concretio silicea bambusae, 20-60 g of radix clematidis, 20-70 g of garden balsam stem and 20-60 g of saussurea involucrate. The invention further provides a preparing method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition can be orally taken and externally applied, and has a remarkable treatment effect on pains, sensation of chill and swelling caused by rheumatic arthritis, rheumatoid arthritis and postpartum rheumatism.

The invention relates to rheumatism expelling bath salt and a preparing method thereof. The rheumatism expelling bath salt comprises, by mass, 80-110 parts of anhydrous sodium sulfate, 2-8 parts of potassium chloride, 4-12 parts of sodium stearate, 15-25 parts of ethyl nicotinate, 30-40 parts of beta-lactose, 25-35 parts of sodium chloride, 10-19 parts of fat alkylamide propyl dimethyl amine oxide, 1.5-6.5 parts of kojic acid, 0.1-0.5 part of pigment, 2-5 parts of jasmine essence, 4-9 parts of carboxy methyl cellulose, 12-20 parts of Chinese starjasmine stem, 10-18 parts of loofah sponge and 8-15 parts of long-noded pit viper. The bath salt can be used for effectively removing dirt on the surface of the skin to make the skin become white, tender, smooth and rich in elasticity, meanwhile, the effect of expelling rheumatism is achieved, and after the bath salt is used for a long time, generation and relapses of rheumatism can be prevented effectively, and rheumatism can be effectively treated.