The invention discloses a no-clean cleaning agent for an automotive interior trim. The no-clean cleaning agent is characterized by including the following aspects that the no-clean cleaning agent is prepared from absolute ethyl alcohol, glycerol, soybean, fructus gleditsiae sinensis, cellulose hydroxyacetate, protease and the like by processing; a processing method of the no-clean cleaning agent comprises the following steps: (1), preparation: soaking the soybean, then pulping to make soybean milk, pressurizing the soybean milk, carrying out oscillation treatment by using an ultrasonic wave, then juicing the fructus gleditsiae sinensis, filtering, afterwards, raising a temperature, and cooking; (2), solvent confection: adding the absolute ethyl alcohol, the glycerol, the cellulose hydroxyacetate and camellia seed oil into water, agitating and mixing to subsequently prepare a solvent solution; (3), mixing: raising a temperature of the solvent solution, adding a soybean extract, fructusgleditsiae sinensis liquid, a willow leaf extracting solution and a pistacia weinmannifolia extract, lowering the temperature to a room temperature, then adding the protease, amylase and magnesium chloride, homogenizing and agitating to subsequently prepare a preliminarily prepared cleaning agent; (4), filtration: putting an electrode into the preliminarily prepared cleaning agent, loading an electric current, carrying out ionization treatment, standing, then filtering by using a microfiltration membrane, and bottling to subsequently prepare the cleaning agent.