The invention relates to the technical field of cultivation, and discloses a disease-resistance improving feed of laying hens. The disease-resistance improving feed is prepared from corn, wheat bran, green grass, black soya bean meal, kelp residues, tea leaf residues, shaddock peels, mango seeds, wool, pig blood, beer fermentation residues, egg shells, vermiculite powder, medical stone powder, composite vitamins, compound amino acid, folium ginkgo polysaccharide, algal polysaccharides, salt and lactobacillus buchneri. The sick rate is reduced to be 6% to 7%, the death rate is 0%, and the economic income is increased by 17.3%; the feed is rich in nutrient, the immunity of laying hens is enhanced, and the price is low; the wool is frozen, boiled and fermented with the lactobacillus buchneri, peculiar smells can be eliminated, palatability can be improved, nutrient absorption can be promoted, and the gastrointestinal functions can be protected; as the egg shells, the vermiculite powder and the medical stone powder can provide rich mineral elements, the laying rate can be increased, the adoption approaches of the egg shells can be increased, and the cultivation income can be increased; when the feed is fractionally added, the absorption and utilization rate is high, the cultivation rate is saved, and the disease resistance is improved.