89 results about "Human organism" patented technology

The present invention relates to a nucleic acid molecule comprised of first and second nucleic acid elements that each bind a target molecule, and a three-way junction operably linking the first and second nucleic elements. Also disclosed is an RNA scaffold comprising first and second RNA receptor regions operably linked by a three-way junction, wherein the first and second RNA receptor regions each comprise a stem defined by at least two sets of consecutive, canonic, paired bases. A method of using a multivalent nucleic acid aptamer to bring a first and second target molecule into proximity of one another is also disclosed. Also disclosed are constructed DNA molecules, engineered genes, transgenic non-human organisms, methods of modifying activity of target molecules, and functional RNA molecules comprising an RNA scaffold and one or more functional modules. A method for modular design and construction of nucleic acid molecules is also disclosed.

The present invention discloses a kind of degradable bone lacuna inside haemostatic material and preparation method thereof which belongs to biological material field. The purpose of the invention is to solve existing problem that bone wax not easily degraded and absorbed, or degradation production tend to initiate inflammation. The haemostatic material described in the invention is composed of 1-10% medical sodium alginate solution in mass concentration and medical faecula which accounts for 15-40% of mass of sodium alginate solution. Inorganic particulate, antibiotic, bone-inducing factor and haemostatic can be further added. Degradable bone lacuna inside haemostatic material can be prepared by mixing medical sodium alginate solution and medical faecula. The haemostatic material of the invention is easy degraded, the degradation production is innoxious and nonirritant to human organisms, and has good ductibility and mechanical strength.

The invention relates to a skidproof nail box of a surgical linear cutting stapler, which is provided with a nail box (6), wherein the upper wall surface of the nail box is provided with a longitudinal cutting groove (62) and the two sides of the cutting groove are respectively provided with a nail outlet hole. The skidproof nail boxis characterized in that the upper wall surface of the nail box is provided with a skidproof convex-concave surface. The skidproof convex-concave surface can effectively prevent human organisms from skidding in an operation process, thereby ensuring surgical cutting and suturing quality.

This invention is in the area of regulatory DNA sequences and their methods of use. Specifically, DNA sequences found in the regulatory region of cytoprotective genes are described that are termed cytoprotective response elements. DNA constructs also are provided that include cytoprotective response elements operably linked to heterologous protein coding sequence, as well as cells and non-human organisms that include the cytoprotective response elements optionally operably linked to a heterologous protein coding sequence, and a method for screening for a compound that increases mRNA or protein regulated by a cytoprotective response element. It has been discovered that the cytoprotective response elements mediate the coordinate activation of certain genes that protect cells from damaging effects of oxidative stress, and that they do so, for example during conditions of hemodynamic shear stress.

The invention discloses a safe medical needle comprising a needle tubule. A second inclined plane and a first inclined plane are positioned at the front end of the needle tubule, and the axial length L1 of the first inclined plane is shorter than the axial length L2 of the second inclined plane; the length L2 of the second inclined plane is preferably 65-75% of the total length L of the two inclined planes, and a small concave arc extending backwards is positioned at an inner point of the needle on the first inclined plane, and the inner point is adjacent to the top end of the arc line. Based on the structure of the former needle, the length L2 of the second inclined plane extends towards the first inclined plane, and a small concave arc is formed on the top end of the arc line of the inner point of the needle by fine grinding, sand blasting or laser beam heat treatment, thus the resistance against insertion of the needle head is reduced, absolute safety is ensured as human organism is not affected, needle insertion is more smooth, amount of bleeding is reduced, and pains of patients can be relieved. The medical needle is a really safe medical needle and can replace all the existing medical needles used in various situations.

The invention provides isolated nucleic acids that encode LCP, including two isoforms, and fragments thereof, vectors for propagating and expressing LCP nucleic acids, host cells comprising the nucleic acids and vectors of the present invention, proteins, protein fragments, and protein fusions of the novel LCP isoforms, and antibodies thereto. The invention further provides transgenic cells and non-human organisms comprising human LCP nucleic acids, and transgenic cells and non-human organisms with targeted disruption of the endogenous orthologue of the human LCP gene. The invention further provides pharmaceutical formulations of the nucleic acids, proteins, and antibodies of the present invention, and diagnostic, investigational, and therapeutic methods based on the LCP nucleic acids, proteins, and antibodies of the present invention.

The invention relates to a quantum biological resonance bed pad, which comprises a bed pad for support horizontal body. Wherein, said bed pad also comprises a quantum generator outside the bed pad, and wires connecting the bed pad and quantum generator; the bed pad has bed pad winding distributed inside whole bed pad; the bed pad has interface via which the wire is connected to the bed pad winding; the quantum generator uses low voltage, to generate impulse current, which via the winding will generate alternative magnetic field; the impulse frequency uses the 50Hz that nears the biological frequency of human cell most as the central frequency; the alternative magnetic field can effective pass human organism to take resonance with body.

A process of concentration by precipitation of PrP^sc for detecting or diagnosing PrP^sc, wherein a tissue or biological fluid stemming from or obtained from an animal or human organism is brought together with an antibiotic from the family of aminoglycosides, preferably streptomycin or one of its derivatives. The use of such an antibiotic for eliminating PrP^sc from a tissue or biological fluid and a kit for diagnosing pathologies associated with the presence of PrP^sc is also disclosed.

The invention relates to a healthy and environment-friendly particle feed for beef cattle, and belongs to the technical field of feed formula. The particle feed is composed of the following components in percentage by weight: 20% to 30% of straw powder, 15% to 25% of soybean meal, 12% to 20% of corn, 10% to 18% of rapeseed meal, 5% to 8% of silkworm excrement, 0.1% to 0.5% of raw ginger powder, 10% to 20% of corn protein feed, 1.5% to 3% of calcium hydrogen phosphate, 2% to 4% of stone flour, 0.5% to 1% of salt, and 0.08% to 1.5% of urea. The feed is prepared according to a natural, pollution-free and environment-friendly feed formula, is rich in a plurality of natural nutrients, can improve the organism resistance and immunity of the cattle, and improves the disease resistant performance of the cattle. The beef produced by the cattle which is fed by the particle feed is healthy, environment-friendly, green, and pollution-free, is benefit for human health, has a strong anti-oxidation performance, and can strengthen the human organism immunity. The particle feed is suitable for scale farming in medium or large scale feeding farms.

The invention relates to a pharmacological composition based on biologically active substances obtained from leaves, stems and fruit of the plant Tribulus terrestris L. to be used as an agent strengthening the immune system, increasing T-cells and anti-bodies number and testosterone quantity in human organism and having a strong anti-virus and anti-inflammatory effect in the form of a medicine or as an addition to food. The pharmacological composition represents a combination of bio-active zinc, bio-active selenium and a complex of steroid saponins obtained from leaves, stems and fruit of the plant Tribulus terrestris l. and consisting of furostanols spirostanols, sapogenins, sterols, flavonoids and other biologically active substances typical of this plant.

The use of sensory G protein-coupled receptors that recognize chemical sensants, parti-cularly those involving olfactory and taste receptors; polypeptide fragments and mutants thereof; classes of such receptors; polynucleotides encoding such receptors, fragments and mutants thereof, and representatives of receptor classes; genetic vectors including such polynucleotides; and cells and non-human organisms engineered to express such receptor complexes, fragments and mutants of an olfactory or taste receptor, and representatives of receptor classes to simulate sensory perception of odorants and tastants is described. The use of such products as a biosensor or a component thereof to detect, identify, measure, or otherwise process the event of binding between the receptor and its cognate ligand (i.e., chemical sensant) is also described. The invention has application, for example, in the design and formulation of odorant and tastant compositions.

Provided is a method for producing a homozygous non-human organism from a heterozygous non-human organism, which homozygous organism can be crossed to obtain a hybrid, comprising providing a heterozygous starting organism; allowing the organism to produce SDR-0 cells through meiosis, which cells originate from second division restitution; regenerating SDR-0 organisms from the SDR-0 cells; and producing the homozygous organism from the SDR-0 organisms thus obtained. Further provided is a method for producing a hybrid, comprising crossing a first homozygous organism that is produced according to the above method with a second homozygous organism. Also provided is a homozygous non-human organism and hybrid non-human organisms obtainable by these methods. In a preferred embodiment, the organisms are plants.

The invention relates to Vitamin D₂ solid dispersion coated tablet and the preparation method, belonging to pharmaceutical preparation technical field. The tablet contains Vitamin D₂ and pharmaceutical excipient, with Vitamin D₂ as the active component. Every ten thousand tablets contain 0.3125g of Vitamin D₂, 100g of PEG-6000, 2500g of starch, 2250g of phosphoric acid calcium hydrogen, 75ml of alcohol, 100g of magnesium stearate and 50g of talc. The invention has a simple preparation method, according to which Vitamin D₂ is coated to produce tablets. The Vitamin D₂ tablets prepared in the method has obvious treating effects and can be taken orally. The toxicity is low and the bioavailability is greatly enhanced. Besides, the tablet has the functions of sustaining, targeting, energy provision for human organism, etc.

The invention belongs to the technical field of brewing of beer, and in particular relates to blueberry beer and a preparation method thereof. The blueberry beer is prepared from the following raw materials in percentage by weight: 40 to 50 percent of water, 15 to 25 percent of barley malt, 5 to 10 percent of wheat, 20 to 25 percent of blueberry juice, 2 to 4 percent of white sugar, 0.1 to 0.3 percent of lupulus, 0.2 to 0.4 percent of yeast, 4 to 8 percent of elderberry juice, and 0.2 to 0.5 percent of edible spices. The raw materials of the blueberry beer provided by the invention are easy to get, and the elderberry has the effects of promoting blood circulation and stopping pain, dispelling wind and promoting dampness, preventing a cold, and increasing the immunity of the organism; the blueberry has the effects of preventing aging of brain nerves, strengthening the heart, resisting cancers and softening blood vessels, and enhancing human organism immunity. The blueberry beer does not only maintain the flavor of the beer, also has a flavor of fruit juice; therefore, the fruity smell is pure, the bouquet is dense, the color of the blueberry beer is blue, a nutritional value is high, and the taste is sweet; moreover, the blueberry beer has a certain health-care effect; the preparation method of the blueberry beer is simple, and is suitable for industrial production.

The invention relates to a soft capsule containing oviductus ranae. The soft capsule comprises content matters and a capsule shell, wherein the content matters contain the following materials in percentage by mass: 10-50% of oviductus ranae meal, 3-30% of ginseng extract, and 20-80% of vegetable oil. The soft capsule is prepared from the ginseng extract and oviductus ranae meal, active ingredients in the ginseng extract and oviductus ranae meal can supplement with each other, namely can be complementary, the oviductus ranae has the effects of tonifying the kidney and nourishing the essence, and nourishing the lung and yin, and ginseng has functions of treating collapse and cardiovascular diseases as well as stomach and liver diseases, so that the soft capsule has the function of tonifying the internal organs of the body in general and is capable of enhancing the human organism immunity and prolonging the service life of the organism after being eaten.

The invention relates to the brewing and non-alcoholic industry and specifically for production of beer, low-alcohol and alcohol-free drinks The “Antioxilen” additive for beer, alcohol-free drinks contains an organic selenium compound—di-(3,4)-methyldipyrazolylselenide (DMDPS)—and also succinic acid and salts thereof (ammonium succinate or sodium succinate) as an antioxidant. The method of conditioning (enriching) drinks involves increasing biological value, improving quality and contributing antioxidant, antitoxic and hepatoprotective properties to drinks, i.e. protective properties for a human organism by adding the above additive to the finished product (drink). The additive is added in the form of a dry mixture or a solution. The invention allows for improving biological value of the product (drink), taste and useful properties thereof and also extending the “life” thereof.

The invention relates to a device with a sensor arrangement, which is able to detect magnetic or magnetized oral administration forms after oral take-up, moreover tracks the dissolution thereof via the reduction or disappearance of the magnetic field of the oral administration form, and with a log function, which records a subjective evaluation on the part of the human wearer of the sensor arrangement during or after the oral take-up.