Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
155 results about "Ethylene Oxide Sterilization" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
Ethylene oxide sterilization is a chemical process consisting of four primary variables: gas concentration, humidity, temperature and time.
Skin antiseptic composition dispenser and methods of use
Skin antiseptic composition dispensers and methods of use are disclosed. The skin antiseptic composition dispenser may include a container with one or more walls that are substantially impermeable to ethylene oxide gas during normal ethylene oxide sterilization processes. In some embodiments, the container may include flexible walls free of metallic foil barrier layers. The containers may also include one or more vents in addition to one or more openings used to dispense the skin antiseptic composition within the container. The dispenser may include an applicator with a hydrophilic foam.
Owner:3M INNOVATIVE PROPERTIES CO
Artificial lens with drug sustained release micro-capsules inlaid on loop and manufacturing method thereof
ActiveCN103156708AReduce inflammatory infectionImprove visual effectsMedical devicesIntraocular lensSurface layerEthylene Oxide Sterilization
The invention relates to an artificial lens with drug sustained release micro-capsules inlaid on a loop and a manufacturing method of the artificial lens. The artificial lens can suppress microbial infection and the like after a cataract surgery effectively. The manufacturing method is simple, mature and practical. The artificial lens with the drug sustained release micro-capsules inlaid on the loop is characterized in that at least one loop hole is formed in the loop, and the sustained release micro-capsules are inlaid in the loop holes. The manufacturing method comprises the following steps: 1) the loop holes are carved in the loop of the artificial lens, ultrasonic cleaning is conducted to the holes and the holes are reserved; 2) inner cores of the micro-capsules are prepared; 3) a plurality of layers of nanometer films are arranged on the inner surface layer of the inner core of each micro-capsule in a self-assembly mode; 4) the obtained micro-capsules are stored in cold, vacuum drying is conducted to the micro-capsules so that dry capsules without water are obtained; 5) the dry micro-capsules are inlaid in the loop holes of the artificial lens under a microscope, and therefore the artificial lens with the drug sustained release micro-capsules inlaid on the loop is manufactured; and then ethylene oxide sterilization and sealed package are conducted.
Owner:SECOND AFFILIATED HOSPITAL ZHEJIANG UNIV COLLEGE OF MEDICINE
Method of packaging and sterilizing disposable articles for surgical operations and such a package
InactiveUS20060231443A1Dispensing apparatusDiagnosticsEthylene Oxide SterilizationBiomedical engineering
A method of packaging and sterilizing disposable articles for surgical operations, in which several surgical articles are packed in a first package that is packed in a transport package and thereafter transported to a plant for sterilizing with the aid of ethylene oxide, whereafter the first package is sterilized in this plant. A second package containing sterile packaged surgical articles of a type, that can not sustain sterilizing, or for other reasons should not be sterilized with ethylene oxide, is brought together with the first package before this package is packed into the transport package and before this package is transported to the sterilizing plant, the second package being impermeable to ethylene oxide. A transport package used in the method and a package for sterile packaged articles, which can not sustain sterilizing or should not be sterilized with ethylene oxide is also disclosed.
Owner:MOLNLYCKE HEALTH CARE AB
Hydrophilic and non-thrombogenic polymer for coating of medical devices
InactiveUS20130323291A1Increased durabilityImprove performanceBiocideSurgeryHydrophilic monomerEthylene Oxide Sterilization
A hydrophilic copolymer is designed and synthesized by copolymerization of an acidic monomer and a second hydrophilic monomer. The copolymer is non-thrombogenic, hydrophilic and incorporates reactive functional groups. The copolymer can then be covalently attached to a primer / base coat through its functional groups, to form a durable lubricious coating on medical devices. A coating formed of the polymer on a surface is non-thrombogenic and non-cytotoxic. The coating shows good stability in gamma ray, e-beam and ethylene oxide sterilization.
Owner:BIOCOAT
Isolated organ preserving device and preserving method thereof
ActiveCN103719075AGuaranteed sterility requirementsGuaranteed partial pressure of oxygenDead animal preservationEthylene Oxide SterilizationCell metabolite
The invention relates to an isolated organ preserving device and a preserving method thereof, and belongs to the technical field of medical equipment. The isolated organ preserving device is structurally characterized in that continuous mechanical irrigation and membrane oxygenation are adopted, an isolated organ continuously obtains nutrients and the oxygen supply, a cell metabolite is removed in time, and a cell microenvironment is better maintained, so that the function normality is ensured. The isolated organ preserving device disclosed by the invention can be used for directly contacting the organ perfusate and the organ perfusion instrument by adopting a disposable consumable material sterilized through epoxyethane, thereby meeting the requirement for sterility of a system. Besides, the isolated organ preserving device disclosed by the invention can be used for judging the consumption of the nutrients contained in the organ perfusate and the gathering degree of metabolic wastes by monitoring the pH value of the organ perfusate in real time and can be used for abandoning the organ perfusate after a certain standard is achieved and replacing the fresh organ perfusate, thereby further ensuring the possibility of long-time preservation; the isolated organ preserving device can be used for evaluating the damage condition of the isolated organ by monitoring the front and back perfusion pressure of the isolated organ in real time and converting the perfusion resistance by combining a flow number.
Owner:江苏赛谷细胞工程研究院有限公司
Skin antiseptic composition dispenser and methods of use
InactiveUS20070276312A1Medical applicatorsInk reservoir pensMetallic foilEthylene Oxide Sterilization
Owner:3M INNOVATIVE PROPERTIES CO
Skin antiseptic composition dispenser and methods of use
Owner:3M INNOVATIVE PROPERTIES CO
Aliphatic polyester double-layered asymmetric guided tissue regeneration membrane and preparation method thereof
ActiveCN103007364AHigh mechanical strengthGood flexibilitySurgeryPolyesterEthylene Oxide Sterilization
The invention discloses an aliphatic polyester double-layered asymmetric guided tissue regeneration membrane and a preparation method thereof. The aliphatic polyester double-layered asymmetric guided tissue regeneration membrane consists of a compact aliphatic polyester layer and a loose aliphatic polyester layer. The preparation method comprises the following steps: preparing an electrospinning liquid A and an electrospinning liquid B through aliphatic polyester; achieving electrostatic spinning film-forming through the electrospinning liquid A and obtaining the compact layer through hot-pressing; achieving electrostatic spinning film-forming on the electrospinning membrane A through the electrospinning liquid B to obtain the loose layer; achieving vacuum drying, solvent removal and freeze drying of a double-layered asymmetric electrospinning membrane; and finally achieving Co<60> radiation or ethylene epoxide sterilization of the double-layered asymmetric electrospinning membrane to obtain the double-layered asymmetric guided tissue regeneration membrane. The invention has the advantages that the preparation method is simple, the preparation efficiency is high, and the prepared membrane has favorable biocompatibility and mechanical property, appropriate degradation rate and excellent attachment property, can well satisfy the clinical requirements for guided tissue regeneration and repair, and is an ideal guided tissue regeneration membrane material.
Owner:北京市意华健科贸有限责任公司
Device and method for treating sterilized ethylene oxide waste gas
InactiveCN103657383AFully dissolveDispersed particle separationEthylene Oxide SterilizationChemical combination
The invention discloses a device and a method for treating sterilized ethylene oxide waste gas. The device comprises a gas pump, a chemical combination device (101), a gas-liquid pump (102), a turbulent ball tower (103) and a diffuser (4). The gas pump conveys ethylene oxide waste gas to the chemical combination device, and the ethylene oxide waste gas is chemically combined in the chemical combination device; ethylene oxide waste gas and a sulfonation reaction agent have a sulfonation reaction in the chemical combination device, and ethylene oxide is oxidized into carbon dioxide and ethylene glycol; the generated carbon dioxide and residual ethylene oxide waste gas are exhausted into the turbulent ball tower; and the residual ethylene oxide waste gas is output into the turbulent ball tower through the gas-liquid pump and is fully mixed and dissolved with hot water pumped into the turbulent ball tower by the gas-liquid pump.
Owner:杨亮月 +1
Coronary artery skeleton medicinal coating for preventing restenosis of blood vessel
InactiveCN1429547AAchieve constant rate releaseOrganic active ingredientsSurgeryEpoxyEthylene Oxide Sterilization
A coated medicine layer on the scaffold in arteria coronaria for preventing angiostenosis is prepared through dissolving the aliphatic polylactone and its copolymer is solvent, adding taxusol, stirring while dissolving, filtering, coating on the scaffold, evaporating the solvent, removing the solvent for 48 hr under vacuum, and disinfecting by epoxy ethane.
Owner:INST OF CHEM CHINESE ACAD OF SCI +1
Skin antiseptic composition dispenser and methods of use
InactiveUS8105306B2Compromising their effectivenessToxic compoundDiagnosticsSurgeryMetallic foilEthylene Oxide Sterilization
Skin antiseptic composition dispensers and methods of use are disclosed. The skin antiseptic composition dispenser may include a container with one or more walls that are substantially impermeable to ethylene oxide gas during normal ethylene oxide sterilization processes. In some embodiments, the container may include flexible walls free of metallic foil barrier layers. The containers may also include one or more vents in addition to one or more openings used to dispense the skin antiseptic composition within the container. The dispenser may include an applicator with a hydrophilic foam.
Owner:3M INNOVATIVE PROPERTIES CO
Medicinal collagen material and its making process
InactiveCN1463984AStable molecular structureGood anti-leakage performanceConnective tissue peptidesPeptide/protein ingredientsEthylene Oxide SterilizationSpinal dura mater
The medical collagen material is made through the processes of chondroitin sulfate crosslinking, high temperature vacuum drying and ethylene oxide. Is has stable molecule structure and better anti-seepage and anti-stick performance, and is used in repairing cerebral dura mater, spinal dura mater and peripheral nerve.
Owner:于海鹰 +1
Ethylene oxide sterilization process indicator inks
Water-based chemical indicator inks for ethylene oxide sterilization processes and methods for its use. The chemical indicator ink contains at least one pH indicator dye selected from the group consisting of Bromocresol green, Bromophenol blue, Methyl red, Ethyl orange, and combinations thereof. The pH indicator dye undergoes an irreversible color change when exposed to ethylene oxide vapor in the presence of low-temperature steam, but when exposed to other sterilization processes either does not undergo a color change or undergoes a color change that is different than is obtained when exposed to ethylene oxide.
Owner:LA CO IND INC
Enzyme matrices for use with ethylene oxide sterilization
InactiveUS20150122647A1Function increaseImprove material propertiesImmobilised enzymesBioreactor/fermenter combinationsGlucose sensorsPyridinium
The invention pertains to analyte sensors designed to include layered compositions that provide these sensors with enhanced functional and / or material properties including, for example, resistance to damage caused by ethylene oxide during sterilization processes. Embodiments of the invention include polyvinyl alcohol N-methyl-4(4′-formylstyryl)pyridinium (SbQ) polymer materials and methods for employing such materials during the ethylene oxide sterilization of glucose sensors.
Owner:MEDTRONIC MIMIMED INC
Ethylene oxide sterilizable, low cost nonwoven laminates with high wet peel strength and improved barrier properties
Owner:AHLSTROM WINDSOR LOCKS LLC
Method for preparing decellularized lamellar cornea matrix sheet
InactiveCN104645415AThe production process is simple and reliableShorten the timeProsthesisAnterior corneaEthylene Oxide Sterilization
Owner:南昌大学第一附属医院 +1
Antigen-removing biological bone and preparation method thereof
The invention relates to a preparation method of an antigen-removing biological bone. The preparation method comprises bone block pretreatment, partial deproteinization treatment, irradiation treatment, organic matter removal, EDC / NHS crosslinking and drying sterilization. Bone particles are treated by irradiation to make proteins degenerated, then a mixed solution of a surface active agent and hydrogen peroxide is used for treating the irradiated bone particles, followed by a hypochlorite solution and a hydrogen peroxide solution are used for treating, and the deproteinized biological bone is obtained after ethylene oxide sterilization. The prepared bone material has a three-dimensional porous structure, has good capillary adsorption, can adsorb osteoblasts and protein factors after being implanted in bodies, and induces new bone formation; the bone material allows antigen components to be effectively removed, retains a part of collagen, and has better biocompatibility; and the bone material allows hydroxy apatite to have the crystallization degree of lower than 15% and exist in a weak crystallization morphology, has no other crystal phases, allows the carbonate content to be 4%-6%, has relatively high mechanical strength and good degradation, and is suitable for a repairing operation material for non load-bearing part bone coloboma.
Owner:SHAANXI BIO REGENERATIVE MEDICINE CO LTD
Natural extracellular matrix biological membrane as well as preparation method and applications thereof
ActiveCN106880872AReduce free waterReduce the binding forceTissue regenerationProsthesisAntigenSurgical operation
The invention provides a natural extracellular matrix biological membrane. The natural extracellular matrix biological membrane is prepared through the steps that natural extracellular matrix after antigen removal is taken as a material, 2-10 layers of monolayer materials with the same specification are placed in a staggered or parallel stacking manner, all the layers attach to each other tightly by adopting clamps, freeze-drying treatment is carried out under the vacuum condition, then the materials are placed in a vacuum oven to be subjected to dehydrothermal treatment, and finally, the extracellular matrix biological membrane is subjected to cobalt-60 irradiation or ethylene oxide sterilization. The natural extracellular matrix material is subjected to a series of antigen removal treatment, thus the biological membrane matrix material with a certain three-dimensional space structure is obtained, the biological membrane matrix material is then subjected to freeze-drying and dehydrothermal treatment, so that the biological membrane matrix material is subjected to intramolecular dehydration crosslinking, the spatial structure is reinforced, the obtained material has high rehydration stability, and the surgical operation is enabled to be more convenient. Meanwhile, the material has long degradation time in the body, the hydrophobicity and mechanical strength are increased, and thus the natural extracellular matrix biological membrane has great significance in isolating the anti-adhesion stress tissue with long repairing period.
Owner:BEIJING DATSING BIO TECH
Infusates with Enhanced pH Stability Under Ethylene Oxide Sterilization
Normal saline and other infusate solutions for infusion into the body of a patient during medical treatment are disclosed. In particular, infusates are disclosed that are formulated to resist changes to the pH of the solution when subjected to sterilization procedures that employ ethylene oxide gas. In one embodiment, a buffered infusate suitable for disposal in a syringe or other container is disclosed. The syringe is sterilizable using ethylene oxide. The buffered infusate comprises an aqueous solution that is disposed in the syringe and is suitable for infusion into a body of a patient. A buffer component is added to the aqueous solution to form a buffered solution. The buffer component is configured to resist a change in the pH of the buffered solution upon exposure of the buffered solution to the ethylene oxide during sterilization of the syringe.
Owner:CR BARD INC
Microwave spectrometer
InactiveUS7057398B2Facilitates parametric releaseEffectivenessResistance/reactance/impedenceLavatory sanitoryEthylene Oxide SterilizationWater vapor
Owner:UBS AG STAMFORD BRANCH AS COLLATERAL AGENT
Extracellular matrix support material and preparation method thereof
InactiveCN102743790AAvoid social ethics issuesWide range of organizationsSkeletal/connective tissue cellsProsthesisCell-Extracellular MatrixFreeze-drying
The invention belongs to the field of biological materials and discloses an extracellular matrix support material and a preparation method thereof. The extracellular matrix support material disclosed by the invention is prepared into a three-dimensional porous support material with a certain pore diameter and porosity through performing in-vitro monolayer high-density culture on immature rabbit bone marrow mesenchymal stem cells and collecting extracellular matrixes secreted by the immature rabbit bone marrow mesenchymal stem cells by applying the freeze-drying technology and a proper cross-linking agent. The material can be trimmed into proper sizes and shapes according to a cartilage defect zone or the requirement of an in-vitro experiment, and the material is sterilized by ethylene oxide to obtain an integral packaging bag. As the stem cells are used as material sources of an extracellular matrix support, the extracellular matrix support material disclosed by the invention is wide in tissue source and strong in multiplication capacity, therefore, the extracellular matrix support material can obtain enough cell quantity per se, and the problems of social ethics involved by embryonic stem cells are avoided.
Owner:金成哲 +3
Preparation method of medicament-carrying biological membrane
ActiveCN102091057AControl release speedWith repair and rebuild functionNervous disorderMetabolism disorderNR1 NMDA receptorEpoxy
The invention discloses a preparation method of a medicament-carrying biological membrane, which comprises the following steps: preparing type I collagen into a porous and degradable collagen spongy carrier by a freeze-drying process by temperature cross-linking; according to the pharmacokinetics of the selected medicaments, adding medicaments with a certain concentration, such as antibiotics, antiepileptic medicaments, nerve growth factors, NMDA (N-methyl-D-aspartic acid) receptor stimulants, NMDA receptor antagonists and the like, into the liquid medicine slowly in the preparation process of slurry, or soaking a biological membrane into the liquid medicine with a certain concentration; adsorbing the medicaments for a period of time; freeze-drying; packaging; and sterilizing in a proper sterilizing mode (gamma rays or epoxy ethane) according to the properties of the medicaments to form a medicament-carrying preparation with a slow-release effect. The invention has wide application prospects in the technical fields of infection prevention, nerve growth promotion, NMDA metabolism, epileptic prevention and the like.
Owner:TIANXINFU (BEIJING) MEDICAL APPLIANCE CO LTD
Oral traditional Chinese medicine for treating chronic nasosinusitis
InactiveCN101085095ASelf-reported decrease in runny noseReduce eye swellingRespiratory disorderPlant ingredientsOral medicationEthylene Oxide Sterilization
The invention discloses an oral administration pharmaceutical composition for treating chronic nasal sinusitis, which is prepared from raw astragalus root 30g, Chinese angelica root 12g, Ligusticum wallichii 10g, ledebouriella root 6g, root of ballon flower 15g, flower bud of lily magnolia 10g, dahurian angelica root 12g, cordate houttuynia 15g, honeysuckle flower 15g and licorice root 6g.
Owner:赵桂琴
Disposable hemodialysis nursing bag
InactiveCN102247629AReduce workloadTime-consuming and labor-intensive solutionDialysis systemsEthylene Oxide SterilizationHaemodialysis machine
The invention provides a disposable hemodialysis nursing bag, which consists of a hemodialysis catheter log-in disposal nursing bag, a hemodialysis catheter log-out disposal nursing bag and an internal fistula puncture nursing bag, wherein the hemodialysis catheter log-in disposal nursing bag and the hemodialysis catheter log-out disposal nursing bag are formed by combining a disposable bed patch pocket, rubber gloves, non-woven fabric treatment towels, iodophor gauze, alcohol gauze, alcohol cotton balls, sterile gauze, needle cylinders, sterile paste, adhesive tapes, catheter caps, disposable treatment discs and an external packaging bag; the internal fistula puncture nursing bag is formed by combining a disposable bed patch pocket, a non-woven fabric treatment towel, rubber gloves, iodophor cotton swabs, dried cotton balls, sterile paste, adhesive tapes, disposable treatment discs and an external packaging bag; and the objects in the three nursing bags are stacked in the respective external packaging bags, are sealed integrally and are sterilized by ethylene oxide. In the disposable hemodialysis nursing bag, all objects are sterilized integrally and can be used while being torn, so that the sterile state in the operating process is ensured, and the chance of cross inflection is reduced; and the objects are not needed to be disinfected independently periodically, so labor and material resources are saved, the using cost is reduced, and the disposable hemodialysis nursing bag is easy, convenient and safe to operate.
Owner:ZHEJIANG UNIV
Aseptic package underwear, and preparation method
An pair of aseptically packed underclothes able to be directly worn is composed of the underclothes and its packing bag. Its preparing method includes such steps as putting the underclothes in a packing bag, sealing, and vacuum sterilizing in an ethylene oxide (EO) sterilizer at 0-100 deg.C under -85-80 Kpa and 30-100% RH for 3-12 hr.
Owner:王基财
Interactive medical wet dressing and its prepn and application
InactiveCN101019793AGood moisture permeabilityHigh strengthAdhesive dressingsAbsorbent padsWound healingPolyvinyl alcohol
The present invention discloses one kind of interactive medical wet dressing and its preparation process and application. The dressing includes one water absorbing core layer and one hydrophobic face layer. The water absorbing core layer consists of fibrous lining material and high hydroscopicity material of polyacrylate, PVA, polyacrylic acid or acrylic acid-acrylamide copolymer; and the hydrophobic face layer is fabric of Dacron, capron, acrylon, etc. The dressing has moisture permeability of 30-70 g / hr.sq cm, low material consumption, low cost, small thickness and great liquid absorption. It is prepared through dispersing high hydroscopicity material grains between two layers of lining, spraying small amount of water, hot pressing at 100-140 deg.c to form the composite water absorbing layer; setting the water absorbing core between two layers of hydrophobic material, sealing at 135-170 deg.c and sterilizing. The dressing is used for wound.
Owner:DONGHUA UNIV +1
Self-cleaning intraocular lens and preparation method thereof
InactiveCN111110397AAvoid stickingSimple processCoatingsIntraocular lensOptical transparencyEthylene Oxide Sterilization
The invention belongs to the technical field of a medical intraocular lens, and particularly relates to a self-cleaning intraocular lens and a preparation method thereof. The preparation method comprises the specific steps of: (1) flushing the surface of an intraocular lens material with sterile double-distilled water, and blow-drying the surface of the intraocular lens material with nitrogen flow; (2) carrying out modification on the surface of the intraocular lens material by utilizing a plasma beam, and filling in O2 to form an oxygen ion beam to impact the surface of the intraocular lens to generate free radicals, so that a certain convex micro-nano structure is formed on the surface of the intraocular lens; (3) grafting the surface of the intraocular lens material, which is subjectedto plasma beam processing, with a PDMS (Polydimethylsiloxane) molecular chain by utilizing a chemical vapor deposition method; and (4) carrying out ethylene oxide sterilization packaging on the grafted self-cleaning intraocular lens. According to the preparation method of the intraocular lens, a coating based on self-cleaning ''similar liquid'' is formed on the surface; and according to the method, optical transparency of the intraocular lens can be kept for the post-cataract surgery, related complications such as posterior capsular opacity and the like can be prevented and treated, and guarantee can be provided for health of cataract patients.
Owner:ZHONGSHAN OPHTHALMIC CENT SUN YAT SEN UNIV
Ethylene oxide sterilization process
InactiveCN109806424AGuaranteed to stay out of explosive limitsStrong penetrating powerChemicalsEthylene Oxide SterilizationAir cleaning
Owner:常熟荣瑞灭菌技术有限公司
Ethylene oxide sterilizable, low cost nonwoven laminates with high wet peel stregth and improved barrier properties
ActiveUS20060052025A1Optimize adhesionOptimize softnessPersonal careDiagnosticsPolymer scienceEthylene Oxide Sterilization
Nonwoven laminate products having improved wet peel strength after aging and ethylene oxide sterilization, and improved drape and softness, which are suitable for medical, surgical and hygienic applications, are produced by laminating one or more nonwoven substrates on one or both sides of a cast film. The cast film is produced using conventional extrusion processes, such as co-extrusion. Multiple extruders are used to process and melt different polymers and then specially designed selector plugs and feed-blocks are used to combine the different polymers into different layers to form a multiple layer structure such as A-B, A-B-A, A-B-C, A-B-B-A, etc.
Owner:AHLSTROM WINDSOR LOCKS LLC
Who we serve
- R&D Engineer
- R&D Manager
- IP Professional
Why Eureka
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Social media
Try Eureka
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap