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45results about How to "Guaranteed sterility requirements" patented technology

Use method of puncture guide device

The invention discloses a use method of a puncture guide device. The use method comprises the following steps: firstly, positioning a surgical part of a patient; and then scanning the surgical part of the patient with CT (computed tomography), and connecting a puncture point and a surgical target point in CT imaging to obtain a puncture path and a puncture depth; calculating a projection angle alpha of an included angle between the puncture path and a sagittal line on a coronal plane, and a projection angle beta of an included angle between the puncture path and a coronal line on a sagittal plane by a CT machine system; adjusting the laser lamp light beam direction and the puncture path direction of the puncture guide device to be conform according to the projection angle alpha and the projection angle beta; adjusting the puncture guide device, so that the laser lamp light beams point to the surgical puncture point; and ensuring that a puncture needle is straight and the tail end of a puncture needle is positioned on a laser lamp light beam line in the follow-up guide. The use method provided by the invention realizes the puncture surgery guide, and is accurate and reliable, and is simple and convenient to use.
Owner:THE SECOND HOSPITAL OF HEBEI MEDICAL UNIV

Carteolol hydrochloride eye drops without bacteriostatic agent and preparation method thereof

The invention discloses bacteriostat-free carteolol hydrochloride eye drops and a preparation method thereof. The bacteriostat-free carteolol hydrochloride eye drops comprise carteolol hydrochloride, a pH regulator, an isotonic agent, a stabilizing agent, a thickening agent, freshener and the like; and the preparation method adopts a bacteria-free bottling process or an autoclaving process. In addition, the eye drops are independently packaged in disposable single dose, thereby the sterility performance of products is guaranteed and the products are more safe, reliable, simple, convenient, and sanitary.
Owner:HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY

Sodium hyaluronate eye drops without bacteriostatic agent and preparation method thereof

The invention discloses bacteriostat-free sodium hyaluronate eye drops and a preparation method thereof. The bacteriostat-free sodium hyaluronate eye drops comprise sodium hyaluronate, a pH regulator, an isotonic agent, a stabilizing agent, and the like; and the preparation method adopts a bacteria-free bottling process or an autoclaving process. In addition, the eye drops are independently packaged in disposable single dose, thereby the sterility performance of products is guaranteed and the products are more safe, reliable, simple, convenient, and sanitary.
Owner:HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY

Disposable levofloxacin hydrochloride eye drops without bacteriostatic agent and preparation method thereof

The invention discloses bacteriostat-free ciprofloxacin hydrochloride eye drops and a preparation method thereof. The bacteriostat-free ciprofloxacin hydrochloride eye drops comprise ciprofloxacin hydrochloride, a pH regulator, an isotonic agent, a stabilizing agent, a thickening agent, and the like; and the preparation method adopts a bacteria-free bottling process or an autoclaving process. In addition, the eye drops are independently packaged in disposable single dose, thereby the sterility performance of products is guaranteed and the products are more safe, reliable, simple, convenient, and sanitary.
Owner:HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY

Preparation method of copper-iron oxide and mixed nanoparticles and antibacterial application

The invention belongs to the technical field of preparation of nanoparticles, and discloses a preparation method of copper-iron oxide and mixed nanoparticles and an antibacterial application. Cu(NO3)2.3H2O and Fe(NO3)3.9H2O in a certain ratio are dissolved in deionized water; a NaOH solution is dropwise added to the mixture under continuous stirring condition; formaldehyde is added to the mixture,the obtained solution is transferred into a SiC reaction tube and subjected to a reaction in a microwave chamber, and copper-iron oxide and mixed nanoparticles are produced; after cooling, a synthesized sample is centrifuged and washed with deionized water; the collected sample is placed in a drying oven and dried overnight. An experiment indicates that the nanoparticles have efficient antibacterial performance on at least nine important human pathogenic bacteria, for example, the nanoparticles can kill escherichia coli at a 10<9>-log reduction speed within 15 min; after incubation is performed for 4 h, about 10<8>-log reduction of klebsiella pneumoniae strains with multidrug resistance is realized .
Owner:赵奕平 +1

Cromoglyn sodium eye drops without bacteria inhibitor and preparation method thereof

The present invention discloses sodium cromoglicate eye drops which do not contain bacteriostat and a preparing method thereof, wherein the sodium cromoglicate eye drops comprise sodium cromoglicate, pH modifying agent, isoosmotic agent, stabilizing agent, thickening agent, algefacient, etc. The preparing method adopts an aseptic manipulation filling technique or hot pressing sterilizing technique. Furthermore the eye drops of the invention adopt a disposable single-dose independent packaging. The sterilized performance of product is guaranteed. The product is safer, more reliable, easier and more sanitary.
Owner:HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY

Naphazoline hydrochloride, chlorphenamine maleate and vitamin B12 eye drops without bacteria inhibitor and preparation method thereof

The present invention discloses a naphazoline hydrochloride, chlorphenamine maleate and vitamin B12 eye drops which do not contain bacteriostat and a preparing method thereof, wherein the naphazoline hydrochloride, chlorphenamine maleate and vitamin B12 eye drops comprise naphazoline hydrochloride, chlorphenamine maleate, vitamin B12, pH modifying agent, isoosmotic agent, stabilizing agent, thickening agent, etc. The preparing method adopts an aseptic manipulation filling technique. Furthermore the eye drops of the invention adopt a disposable single-dose independent packaging. The sterilized performance of product is guaranteed. The product is safer, more reliable, easier and more sanitary.
Owner:HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY

Gernebcin eye drops without bacteriostatic agent and preparation method thereof

The invention discloses bacteriostat-free tobramycin eye drops and a preparation method thereof. The bacteriostat-free tobramycin eye drops comprise tobramycin, a pH regulator, an isotonic agent, a stabilizing agent, a thickening agent, and the like; and the preparation method adopts a bacteria-free bottling process or an autoclaving process. In addition, the eye drops are independently packaged in disposable single dose, thereby the sterility performance of products is guaranteed and the products are more safe, reliable, simple, convenient, and sanitary.
Owner:HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY

Tropicamide eye drops without bacteria inhibitor and the preparation method thereof

The present invention disclose a tropicamide eye drops without bacteria inhibitor and the preparation method thereof, which comprises tropicamide, pH regulating agent, isotonic agent and stabiliser etc. sterile operation loading process or heat pressing sterilizing process is adopted in the preparation, and disposable single dose independent packaging is used in the eye drop through the present invention, so that sterilized performance is guaranteed to make product more secure, reliable, sanitary, simple and convenient.
Owner:HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY

Levofloxacin single-dose eye drops and preparation method thereof

The invention belongs to the field of pharmaceutical preparations and provides levofloxacin single-dose eye drops. The levofloxacin single-dose eye drops comprise an active component, namely levofloxacin, an isotonic regulator selected from sodium chloride, disodium hydrogen phosphate and sodium citrate, a pH regulator selected from hydrochloric acid, sodium dihydrogen phosphate and citric acid, and water for injection. The invention further provides a preparation method of the single-dose eye drops. The levofloxacin single-dose eye drops prepared by the preparation method provided by the invention do not contain preservatives, so that potential danger and toxic and side effects to eyes caused by the preservatives are avoided, and the levofloxacin eye drops which are safer and more reliable are provided for patients.
Owner:ZHUHAI ESSEX BIO PHARMA

Copper-containing ferrite nanoparticles as well as preparation method and antibacterial effect thereof

The invention discloses copper-containing ferrite nanoparticles as well as a preparation method and antibacterial effect thereof. A structural formula of the copper-containing ferrite nanoparticles isCu0.5Fe<(II)>0.5Fe<(III)>2O4. 1 / 2 of ferrous iron in Fe3O4 nanoparticles is replaced with divalent copper, so that the electron coupling effect in the Cu0.5Fe<(II)>0.5Fe<(III)>2O4 is eliminated. Theobtained nanoparticles Cu0.5Fe<(II)>0.5Fe<(III)>2O4 have a very excellent antibacterial effect, can effectively avoid the progress of bacteria to drug-resistant bacteria, and have a wide application prospect.
Owner:GANNAN MEDICAL UNIV +1

Chloromycetin eyedrops without bacteriostatic agent and preparation method thereof

The invention discloses bacteriostat-free chloromycetin eye drops and a preparation method thereof. The bacteriostat-free chloromycetin eye drops comprise chloromycetin, a pH regulator, an isotonic agent, a stabilizing agent, a thickening agent, and the like; and the preparation method adopts bacteria-free bottling process or autoclaving process. In addition, the eye drops are independently packaged in disposable single dose, thereby the sterility performance of products is guaranteed and the products are more safe, reliable, simple, convenient, and sanitary.
Owner:HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY

Instant compound oleum lithospermi dressing and preparation method thereof

The invention discloses instant compound oleum lithospermi dressing and a preparation method thereof. The dressing is prepared from the following components in parts by mass: 55-65 parts of radices lithospermi, 75-85 parts of polygonum cuspidatum, 2-8 parts of borneol, 40-60 parts of vitamin E oil, 1-3 parts of inositol hexaphosphate and 900-1100 parts of olive oil. The preparation method combinesthe negative pressure drying technology and micron sterilization technology, can be used for furthest ensuring efficient extraction of medicinal material and sterile requirement for later medicinal oil dressing.
Owner:THE PEOPLES HOSPITAL SHAANXI PROV

Enclosed bioreactor and cell culturing method thereof

ActiveCN108977358AEasy to clean high pressureLow sterility requirementsBioreactor/fermenter combinationsBiological substance pretreatmentsPerfusion CultureVaccine Production
The invention discloses an enclosed bioreactor. The enclosed bioreactor comprises a solution container, a collection container, a bioreaction tank, a liquid inlet pipeline and a liquid outlet pipeline, wherein the liquid inlet pipeline and the liquid outlet pipeline are provided with one four-way joint respectively. The invention further discloses a cell culturing method of the enclosed bioreactor. The cell culturing method comprises pre-culturing, bioreactor cell inoculation, bioreactor cell perfusion culture, bioreactor virus vaccination, bioreactor washing and replacement as well as bioreactor virus perfusion culture. By adopting the enclosed bioreactor, bioreactor perfusion culture can be realized, rapid liquid exchanging is realized, high-pressure cleaning is facilitated, repeated used is realized, the production cost is reduced, the pollution risk can be lowered, and the working efficiency is improved. By adopting the enclosed bioreactor and the cell culturing method thereof disclosed by the invention, the production operation of the bioreactor with a single pipeline in the existing method is substituted, and the aseptic requirement in vaccine production is effectively ensured. The enclosed bioreactor is easy and convenient to operate, and is suitable for fixed bed bioreactor large-scale culture.
Owner:GUANGZHOU PROMISE BIOLOGICAL PROD

Hydrochloric acid melphalan injection liquid and preparation method thereof

The invention relates to the technical field of medicine preparations. The hydrochloric acid melphalan is very unstable in water, and a large amount of medicine degrades after several hours to generate impurities causing toxic or side effect, so the hydrochloric acid melphalan is not suitable for being prepared into medicine water solution to be stored for a long time. The invention provides stable hydrochloric acid melphalan injection liquid, which consists of hydrochloric acid melphalan, injection-use solvents and pH value regulating agents, wherein the injection-use solvents are anhydrous solvents obtained through dewatering treatment. The hydrochloric acid melphalan injection liquid of the invention has the advantages of stable preparation, low cost, autoclaving capability and small toxic or side effect.
Owner:上海丽思化工科技有限公司

Cultivation method of grifola frondosa

The present invention provides a cultivation method of grifola frondosa. The cultivation method includes: step S1, proportioning of production materials; step S2, pretreatment of raw materials of a culture medium; step S3, mechanical agitation and bottling; step S4, sterilizing and cooling; step S5, inoculation; step S6, mycelium cultivation; and step S7, cultivation for fruiting, namely transferring a cultivation bottle for cultivating mycelia in step S6 into a cultivation room, and adjusting and setting parameters including illumination, temperature, humidity and carbon dioxide concentrationin the cultivation room to ensure that the mycelia in the cultivation bottle further complete growth until fruiting. By using the cultivation method of grifola frondosa, provided by the present invention, the yield of the grifola frondosa may be effectively increased, and the quality of a finished product of the grifola frondosa produced by using an existing cultivation technology may be remarkably improved, so that the cultivation method is very suitable for industrial popularization.
Owner:HUNAN HEPING BIOLOGICAL TECH CO LTD

Transferring equipment for infusion apparatuses

The invention provides transferring equipment for infusion apparatuses. The transferring equipment comprises a machine frame, a clamp which is arranged on the machine frame and is provided with a containing cavity used for containing the infusion apparatuses, and a pushing mechanism which is arranged on the machine frame and is used for pushing out the infusion apparatuses located in the containing cavity. According to the transferring equipment, the problems that in the prior art, when the infusion apparatuses are manually put into packaging bags, the operation efficiency is low, and asepsisrequirements are difficult to ensure can be solved.
Owner:MAIDER MEDICAL IND EQUIP

Method for utilizing mash waste heat during alcohol production process

The invention discloses a method for utilizing mash waste heat during an alcohol production process. The method comprises the following steps: (1) pumping 80 DEG C liquid mash into a heat exchanger for heat exchanging; (2), pumping 80 DEG C liquid vinasse into a heat exchanger for heat exchanging; (3), leading 68 DEG C liquid mash and 68 DEG C liquid vinasse which are produced after heat exchanging out for the next process; and (4), mixing the recycled heat quantity, and leading the mixed heat quantity into a circulating cooling water system through an electric control system. According to the method, the 80 DEG C liquid mash and the 80 DEG C liquid vinasse produced during the alcohol production process are utilized; an HR waste heat recovery system which is domestic professional equipment is adopted; the part of heat quantity is recovered to produce 18 DEG C chilled water, so as to control the fermentation temperature to be 30 to 32 DEG C; not only the temperature controlling ensuring annual normal alcohol fermentation but also waste heat utilization are realized; the refrigeration cost is reduced; and the production benefit is improved stably.
Owner:吴江永祥酒精制造有限公司

Multilayer co-squeeze film for transfusion

A multilayer common squeezed film for transfusion is composite with five layers, the first layer is high elasticity, high intensity and high obstruct special polyethylene glycol terephthalate, the second layer is ethylenemethacrylic acid copolymer, the third layer is metallocene polyethylene, the forth layer is the dibasic ethylene ethylene-propylene copolymer and the fifth layer is quick-speed heat-sealing copolymerization polypropylene which has perfect chemical stability. This invention is a five layers common squeezed casing film for transfusion which is nonhazardous, high anti-dampness, high antioxidation, high-temperature, high-transparency, good-pliability, low-temperature and good-Intensity of heat seal.
Owner:李长青 +1

Rice anther segmentation apparatus

The invention discloses a rice anther segmentation apparatus, which includes a housing (1); the housing (1) is internally provided with a paddle plate (13) with a paddle plate shaft (12); a link mechanism below the paddle plate (13) can drive the paddle plate (13) to reciprocate; the top of the housing (1) is provided with a sterilization mechanism; the sidewall of the housing (1) is provided with a discharge outlet (17) capable of cooperating with the paddle plate (13); the lower side of the discharge outlet (17) is provided with a transmission mechanism (18); the end of a transfer mechanism (18) is provided with a cutting board (19); a blade group (20) is above the cutting board (19); the end of the cutting board (19) is provided with a discharge port (21) and a storage bin (22) cooperating with the discharge port (21); the bottom of the cutting board (19) is provided with a drain pipe (16) with a liquid outlet valve (15) at the end. The device has simple structure, and is easy to use, applicable to cutting of rice anther, and improves anther culture efficiency.
Owner:XUZHOU XUANKE AGRI MASCH CO LTD

Living body sampler of which sampling head is replaceable

The invention relates to a living body sampler of which a sampling head is replaceable. The living body sampler of which the sampling head is replaceable comprises a handheld frame, wherein a samplinginserting pipe is mounted on the handheld frame; a sampling inserting rod is mounted in the sampling inserting pipe; the sampling inserting pipe can move in an axial direction relative to the sampling inserting rod; the sampling head is mounted at the end of the sampling inserting rod in a replaceable manner; and the sampling head is provided with an accommodating space for accommodating tissue samples. According to the living body sampler of which the sampling head is replaceable disclosed by the invention, after each sampling is completed, the sampling head is replaced, so that the occurrence of the situation that cross-infection is generated between different living bodies is avoided; the replaced sampling head can be integrally put in a freezing vessel for storage, so that in the removing process, the sterile requirements are guaranteed, and an operator can easily collect the desired tissue samples; and the living body sampler is very practical.
Owner:HENAN AGRICULTURAL UNIVERSITY

High-barrier medical film

The invention relates to a high-barrier medical film which is prepared from five layers of resin materials through coextrusion, wherein the first layer is a heat sealing layer as an inner layer A and comprises the components of high-melting-point metallocene polypropylene and ethylene-octene copolymer (EOC) through mixing, and the addition quantity of the EOC in the mixture is 10%-30%; the second layer is a barrier layer as a secondary inner layer B and comprises the component of cycloolefin copolymer; the third layer is a core layer as an intermediate layer C and comprises the components of polypropylene and styrene-ethylene-butylene-styrene (SEBS) through mixing, and the addition quantity of the SEBS in the mixture is 20%-40%; the fourth layer is an adhesion layer as a secondary outer layer D and comprises the component of anhydride modified polypropylene copolymer; and the fifth layer is a weather-proof layer as an outer layer E and comprises the component of a segmented copolymer of polyethylene naphthalate and polyethylene terephthalate. A soft bag made of the medical film has good barrier performance, optical performance and safety performance, and is especially suitable for being used as a packaging material of therapeutic transfusions, nutrition transfusions, powder injections and small-volume injections.
Owner:湖北恒泰橡塑有限公司

Off-line sterilization method of a respirator on a buffer tank

ActiveCN103705949BAchieve sterilizationSimplify the sterilization processLavatory sanitoryDisinfectionBuffer tankRespirator
The invention provides an offline sterilization method for a breather on a buffer tank. The method comprises the following steps: removing a combination of the breather and a breather hand valve, sealing a breather opening in the buffer tank by using a sealing plate, and automatically cleaning and sterilizing the buffer tank; then mounting an auxiliary hand valve below the breather hand valve, opening the breather hand valve, closing the auxiliary hand valve, and wholly putting and sterilizing the combined breather, breather hand valve and auxiliary hand valve in a sterilization cabinet; detaching the auxiliary hand valve under level-A laminar flow of a filling machine after the whole sterilization operation of the combined breather, breather hand valve and auxiliary hand valve is finished, and mounting the combination of the breather and the breather hand valve on the breather opening in the buffer tank. According to the method provided by the invention, the defects in the prior art are overcome, complete sterilization of the breather can be realized, the sterilization program is simplified, the time is saved, the production efficiency is improved, the cost is reduced, and sterile requirements can be guaranteed.
Owner:上海东富龙拓溥科技有限公司 +1

A kind of rice anther dividing device

The invention discloses a rice anther segmentation apparatus, which includes a housing (1); the housing (1) is internally provided with a paddle plate (13) with a paddle plate shaft (12); a link mechanism below the paddle plate (13) can drive the paddle plate (13) to reciprocate; the top of the housing (1) is provided with a sterilization mechanism; the sidewall of the housing (1) is provided with a discharge outlet (17) capable of cooperating with the paddle plate (13); the lower side of the discharge outlet (17) is provided with a transmission mechanism (18); the end of a transfer mechanism (18) is provided with a cutting board (19); a blade group (20) is above the cutting board (19); the end of the cutting board (19) is provided with a discharge port (21) and a storage bin (22) cooperating with the discharge port (21); the bottom of the cutting board (19) is provided with a drain pipe (16) with a liquid outlet valve (15) at the end. The device has simple structure, and is easy to use, applicable to cutting of rice anther, and improves anther culture efficiency.
Owner:XUZHOU XUANKE AGRI MASCH CO LTD

An auxiliary device for cultivating rice flowers

The invention discloses a rice anther culture breeding auxiliary device. The device is characterized by comprising the following parts: a sterilizing water tank and a disinfectant tank, which can sterilize and clean inner cavity of the device and spikes of rice, and create a sterile condition; a rocker panel, which can achieve fully mixing of spikes of rice, disinfectant fluid and disinfected water; a the link mechanism, which can achieve reciprocated movement of the rocker panel; a drain pipe, which can smoothly discharge waste liquid in the tank; a cutting board and a blade group, which can achieve rapid segmentation of spikes of rice; a storage bin, which can collect segmented rice spike slices; and a conveyor belt with triangle projection, which is convenient for lateral convey and cutting of spikes of rice; The device provides a sterile conditions for transverse cutting of spikes of rice, provides a large number of sterile slices of rice spike for further centrifugation extraction of rice anther for anther culture; and the device cuts spikes of rice, centrifuges and extracts anther for rice anther culture breeding, and can greatly improve the efficiency of anther culture, and significantly reduce the breeding costs.
Owner:新沂市芭缇雅商贸有限公司

Disposable integral midwifery drape as well as folding method and application thereof

The invention discloses a disposable integral midwifery drape. The disposable integral midwifery drape forms a sterile operation area for midwifery at the perineum of a puerpera; the sterile operation area is composed of a middle part arranged between the two legs and used for covering the perineum and leg protecting parts arranged on the two sides of the middle part and used for covering the legs; and the middle part and the leg protecting parts on the two sides are connected into a whole. The middle part comprises a belly protecting part covering the belly and a midwifery extending part covering the table top; the abdomen protecting part, the midwifery extending part and the leg protecting parts on the two sides define a sterile midwifery operation area at the perineum of the puerpera. The invention further relates to a folding method and the application of the drape. According to the paving towel, preparation of the whole paving towel can be completed only by opening the paving towel in several simple steps, and due to the overall design, the paved paving towel does not slip off; the leg is quickly and simply fixed and protected on the leg, so that the time for paving the towel is saved; and after the whole drape is folded, the drape surface layer is clamped in the drape block, so that the sterile requirement of the drape is ensured.
Owner:伍菲菲

Burn earmuffs for oxygen tube protection

The invention belongs to the technical field of medical equipment, and particularly relates to a burn earmuff for protecting an oxygen tube. The earmuff comprises earmuffs, an arc-shaped head frame, an arc-shaped bracket, the oxygen tube, a sliding block, an air conveying head and a sponge cushion, the earmuffs are connected through the arc-shaped head frame; the air conveying head is mounted on the sliding block; the other end of the oxygen tube is connected with an oxygen bottle; the sponge cushion is mounted on the inner side wall of the arc-shaped head frame and is connected with the sliding block through a string, so that the sponge cushion can be tensioned through the string when the sliding block slides in a sliding groove; through cooperation of the earmuffs, the arc-shaped bracket, the oxygen tube, the sliding block, the air conveying head and the sponge cushion, the oxygen supply effect on a patient is achieved; when the air conveying head slides on the arc-shaped bracket, the sponge cushion is in a tightened state by pulling the string, so that the fixation of the earmuff position is enhanced, the earmuff is prevented from falling off when the patient sleeps and turns over at night, the use effect of the earmuff is enhanced, and the practicability of the earmuff is enhanced.
Owner:QINGDAO CENT HOSPITAL
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