245 results about "Aerosol inhalation" patented technology

The present disclosure relates to an exemplary aerosol generating device for heating a tobacco block. The aerosol generating device includes a shell, a mouthpiece assembly at an end of the shell, and an atomizing assembly received in the shell. The atomizing assembly includes a hollow heating body configured for inserting into the tobacco block. The heating body includes an inner surface and an outer surface for heating the tobacco block.

The invention discloses a baking type atomization device which comprises a shell, a baking chamber arranged in the shell, a heating unit, an air inlet and an air outlet. The baking chamber is sleeved with the heating unit. The baking type atomization device further comprises an air guide ring, the air guide ring is provided with a cavity suitable for containing the baking chamber, a first gap communicated with the air inlet is arranged between the outer wall of the air guide ring and the inner wall of the shell, and a second gap for being communicating the first gap and the baking chamber is arranged between the heating unit and the inner wall of the air guide ring. According to the baking type atomization device and an aerosol inhalation device, the double-heating mode of circumferential type heating and thermal current heating is used for heating the baking chamber and preheating air in the second gap, so that the temperature in the baking chamber rises rapidly, the baking time is shortened greatly, therefore, rapid heating is achieved, electric energy is saved effectively, and the heating efficiency is improved. The invention further provides the aerosol inhalation device with the baking type atomization device.

An aerosol inhalation system has an inhalator (2) having an aerosol-generating passage (8) connecting an outside air inlet (6) and a mouthpiece (4) to each other, in which a part of the passage (8) is made up of a tubular electric heater (12); a flexible storage bag (14) prepared separately from the inhalator (2) and containing a solution that is a source of aerosol; and a feed pipette (16) connecting the bag (14) to the inhalator (2), in which the feed pipette (16) has a feed opening (20) opened in the passage (8) and disposed upstream of the heater (12), the solution in the bag (14) is sucked out of the feed opening (20) into the passage (8) and then transferred to the heater (12) with an intake airflow running towards the mouthpiece (4) when the user inhales, the sucked-out solution is heated by the heater (12) to be evaporated, and aerosol is thus generated in the intake airflow.

The present disclosure relates to an exemplary aerosol generating device for heating a tobacco block. The aerosol generating device includes a shell, a mouthpiece assembly at an end of the shell, and an atomizing assembly received in the shell. The atomizing assembly includes a hollow heating body configured for inserting into the tobacco block. The heating body includes an inner surface and an outer surface for heating the tobacco block.

In a first aspect, the invention relates to a method for operating an aerosol inhalation device (10), comprising the steps of transporting a certain amount of an aerosol to a desired location outside said device (10) and vibrating the transported aerosol when it has reached said desired location. In a second aspect, the invention relates to an aerosol inhalation device (10) comprising a pump (1) for flowing a certain amount of an aerosol to a desired location outside the device (10), a vibrator (2) for vibrating the transported aerosol in a vibration mode and a control configured to actuate the vibrator (2) for vibrating the flowed aerosol only when it has reached said desired location.

Disclosed is an electronic cigarette including: a main body portion including a main body cover; an intake portion that generates an aerosol by power supply, sucks the aerosol, and is detachably coupled to the main body portion, and a sliding portion coupled to the main body portion and performing a reciprocating sliding motion and including a slide cover. The electronic cigarette includes a sliding close state in which the main body portion and the sliding portion are pulled to each other and a sliding open state in which the main body portion and the sliding portion are pushed to each other.

The invention discloses an electronic cigarette convenient for aerosol inhalation. The electronic cigarette comprises a cigarette holder, an electronic cigarette housing, a smoke atomizing chamber and a fuel guide rope; the electronic cigarette housing is vertically provided with a smoke outlet tube whose top part is connected with the cigarette holder and the bottom part is connected with the smoke atomizing chamber; a tobacco tar chamber is formed by the cigarette holder, the electronic cigarette housing, the smoke outlet tube and the smoke atomizing chamber in a surrounding mode; the bottom of the tobacco tar chamber is provided with a porous penetrating plate whose bottom is connected with the fuel guide rope inside the smoke atomizing chamber; the bottom of the fuel guide rope is connected with heating wires; the bottom of the smoke atomizing chamber is connected with a plug; the middle of the plug is provided with an air inlet tube. The electronic cigarette convenient for aerosol inhalation is convenient for the exportation and uniform distribution of tobacco liquid or tobacco tar, the operation of the heating wires and the vaporization when the tobacco liquid reaches the boiling point so as to generate smoke; thus it is convenient to blow the smoke generated inside the smoke atomizing chamber to enter the cigarette holder along the smoke channel and to enter the mouth of a human body so that the atomizing effect of tobacco tar is improved.

Pooled human plasma is processed by cold ethanol fractionation to produce purified immunoglobulin G antibodies for intravenous administration. Immunoglobulin A is an unwanted by-product since intravenous administration of immunoglobulin A-containing immunoglobulin G can cause life-threatening anaphylaxis in some people. The present invention is the topical application of immunoglobulin A coupled with J chain, and optionally coupled with secretory component in order to render the immunoglobulin A more physiologically active, for the prevention or treatment of ocular diseases including ocular immune deficiency and infections. Antigen-specific monoclonal immunoglobulin A may be used.

The invention provides a preparation method of a glucocorticoid aerosol inhalation suspension. The method comprises the following steps: (1) preparation of a mixed liquid, namely dispersing glucocorticoid into a water solution, and obtaining a mixed liquid containing a glucocorticoid insoluble medicine; and (2) high-pressure homogenization, namely homogenizing the mixed liquid through a high-pressure homogenizer until the particle size distribution is d(v, 0.5)=1-3 microns, so as to obtain the suspension. The preparation method also can comprise the steps of filling and sterilizing; the finally obtained glucocorticoid aerosol inhalation suspension comprises glucocorticoid and a water solution; the particle size distribution is d(v, 0.5)=1-3 microns; and the components also can comprise medicinal additives including a pH modifier, a suspending agent, a wetting agent and an isoosmotic adjusting agent. By virtue of a high-pressure homogenization crushing method, all defects of an airflow crushing method can be effectively solved; and the obtained product is relatively good in appearance, and is free of instability phenomena such as FPF and FPD reduction.

The invention relates to a method and apparatus for heat stress testing medicament aerosol inhalation devices, such as metered dose inhaler. An electrical induction work coil (24, 26, 28) is used to heat the inhalers to 55° C.±5 C.°. Heated inhalers are subsequently weighed to detect and reject nonconforming inhalers where a nonconforming amount of propellant has leaked.

The aerosol inhalation device is manually operated and comprises a holding part (3) for receiving an aerosol container with a valve and an outlet tip, and an inspiratory part (1), which at one end comprises a mouthpiece (2), in which inspiratory part (1) a member (4) for passage of aerosol is provided for receiving the outlet end of the aerosol container and comprising a conduit (5) with an outlet opening for discharging aerosol into the inspiratory part in the direction towards the mouthpiece (2). At the end opposite the mouthpiece (2) the inspiratory part (1) is open towards the surroundings such that air may pass freely from the surroundings past the member (4) for passage of aerosol and out through the mouthpiece (2).

The invention relates to a respirator with aerosol inhalation function for pneumology department, and belongs to the technical field of medical apparatuses and instruments. A hose is connected to the respirator, a clamping connector is arranged on the hose and connected with an atomizer, and a switch valve is arranged on the atomizer. An elastic diaphragm is arranged on the portion, between the outlet of the atomizer and the outlet of the hose, on the hose and provided with a buffer cavity. A gas guide buffer is arranged in the buffer cavity. The respirator with the aerosol inhalation function can be used by patients using the respirator.

Pooled human plasma is processed by cold ethanol fractionation to produce purified immunoglobulin G antibodies for intravenous administration. Immunoglobulin A is an unwanted by-product since intravenous administration of immunoglobulin A-containing immunoglobulin G can cause life-threatening anaphylaxis in some people. The present invention is the aerosol administration, by metered dose inhaler or nebulizer, of by-product immunoglobulin A for the prevention or treatment of diseases including immunodeficiencies and infections. Antigen-specific monoclonal immunoglobulin A may be used. Immunoglobulin A from any of the aforementioned sources may then be coupled with recombinant J chain, and may then be additionally coupled with recombinant secretory component in order to render the immunoglobulin A more physiologically active. Immunoglobulin A, with or without J chain and secretory component, is then administered by aerosol inhalation.

The invention discloses an aerosol inhalation device used in the paediatric internal medicine. An aerosol transfer chamber is used for separating the mouth of a sick child and an aerosol machine; gas expired by the sick child enters a disinfection device from an exit pipe at the lower part of the aerosol transfer chamber for disinfection and then is discharged, so as to prevent cross infection during use; a hose is used, and thus the use is free and flexible; a nipple-like inspiratory nozzle is designed, so that the sick child can suck the nipple-like inspiratory nozzle, and the fear of the sick child in treatment can be reduced; a fog amount adjusting button is adopted, thus the amount of fog can be regulated according to the different requirements of the sick child, the requirements of different sick children are effectively met, and the work difficulty of medical workers is reduced. According to the aerosol inhalation device, aerosol treatment and oxygen treatment can be performed simultaneously by means of a support pipe, a biting nozzle, the adjusting button, activated carbon fiber, a hollowed-out ventilation fixed piece and a flexible piece, deep filtering of waste gas is facilitated, the cross infection is prevented, the fog amount can be controlled, tracheal spasm and difficult breathing are prevented, the use is further facilitated, and the service life is prolonged.

This patent application is for an apparatus to safely expose guinea pigs and other small animals to biohazardous aerosol. It is composed of three main chambers housed in an outer box which fits within a conventionally sized biosafety cabinet. The animal chamber contains a removable housing unit for four or eight guinea pigs. The aerosol chamber is separate to minimize fur contamination. The nebulizer chamber is also sealed to reduce risks from leakages. This apparatus is easily decontaminated by immersion in disinfectant. The first version of the prototype, tentatively named the AXS1, has been tested for safety, ergonomics, efficiency of rodent exposure to bacteria, airflow, access points, seal mechanisms, and size.

The invention discloses an aerosol inhalation device for the pediatric department. The device comprises a device main body, one end of the device main body is provided with a solution cup containing cavity in the longitudinal direction, the solution cup containing cavity is of a cylindrical hollow structure, a heating metal tube is spirally arranged on the inner wall, an ultrasonic atomization device is installed at the bottom of the solution cup containing cavity, clamping mechanisms are symmetrically arranged at an opening formed in the upper end of the solution cup containing cavity, a liquid medicine cup is installed in the solution cup containing cavity, a sealing cover is in threaded connection with an opening formed in the upper end of the liquid medicine cup, clamping grooves are symmetrically formed in the outer side wall, located at the opening, of the liquid medicine cup, the clamping mechanisms are clamped in the clamping grooves, and a stirring paddle is rotationally installed in the center of a circle of the side, facing the interior of the liquid medicine cup, of the sealing cover. The device is novel in design, simple in structure, convenient to use, convenient to carry and capable of heating atomized liquid medicine, cleaning and disinfection of the liquid medicine cup are conducted conveniently, the use comfort level is improved, and the use requirements of auser are met.

A process for manufacturing bulk solutions and lyophilized α-aztreonam lysinate for large scale production of an inhalable aztreonam. A purified α-aztreonam lysinate for inhalation. Dry powder or lyophilized α-aztreonam lysinate composition for dry powder or aerosol inhalation.

Actuators for an aerosol inhalation device containing a housing adapted to receive an aerosol canister containing a pressurized medicament formulation, a mouthpiece portion through which the user inhales, a nozzle block and an orifice and a tubular element extending in the mouthpiece portion from the orifice aperture in a longitudinal axis substantially aligned with a longitudinal axis of the mouthpiece portion provide a significant reduction in the non-respirable, coarse fraction of the emitted aerosol medicament via inertial impaction and retention in the actuator than in the oro-pharynx, with consequent less associated side effects and oral candidiasis in the patient. In addition the presence of the tubular element has minimal, negligible impact on the fine particle dose and on the particle size distribution (PSD) of the delivered particles having aerodynamic diameter lower than 9 μm.

The present invention provides a process for producing a water-miscible metalworking fluid involving combining about 90 wt. % to about 5 wt. %, based on the weight of the fluid, of water and one or more additives chosen from plasticizers, chelating agents, biocides, surfactants, dispersants, dyes, odorants, extreme pressure agents, anti-oxidants and corrosion inhibitors with about 10 wt. % to about 95 wt. %, based on the weight of the fluid, of a polyether polyol produced by mixing an active hydrogen compound with a double metal cyanide (DMC) catalyst in a reactor vessel, charging to the reactor vessel a mixture containing two or more alkylene oxides to activate the catalyst, and continuously feeding one or more alkylene oxides to produce the polyether polyol, wherein a 1% solution in water of the polyether polyol has a cloud point of from greater than about 32° C. to less than about 53° C., the polyether polyol has a number average equivalent weight of from greater than about 1,600 Da to about 10,000 Da, and a four-hour aerosol inhalation exposure to the polyether polyol has a LC50 of greater than about 5 mg / L. The water-miscible metalworking fluid produced by the inventive process may find use in cooling and / or lubricating metal surfaces during one or more of grinding, cutting, boring, drilling and turning of metal parts.

The invention belongs to the technical field of pharyngitis treatment, aims to solve the problems of long course of treatment and poor effect of the conventional traditional Chinese medicine for treating pharyngitis and provides a traditional Chinese medicine atomizing agent for treating pharyngitis. The traditional Chinese medicine atomizing agent is prepared from dried rehmannia root, scrophulariae, Chinese wolfberries, platycodon grandiflorum, red peony roots, honeysuckle, boat-fruited scaphium seeds, radix ophiopogonis, periostracum cicada and radix glycyrrhizae according to a certain ratio. The traditional Chinese medicines are decocted with conventional water for obtaining medical liquid, the medicine reaches to an affected part through aerosol inhalation, is quick in taking effect, and small in using amount, the concentration of the partial medicine is high, and the respiratory symptom can be improved rapidly. The traditional Chinese medicine atomizing agent can effectively relieve the symptoms of throat red and swollen, urtication, foreign body sensation, cough, difficulty in expectoration, hoarseness and the like.

The present invention provides a process for producing a water-miscible metalworking fluid involving combining about 90 wt.% to about 5 wt.%, based on the weight of the fluid, of water and one or more additives chosen from plasticizers, chelating agents, biocides, surfactants, dispersants, dyes, odorants, extreme pressure agents, anti-oxidants and corrosion inhibitors with about 10 wt.% to about 95 wt.%, based on the weight of the fluid, of a polyether polyol produced by mixing an active hydrogen compound with a double metal cyanide (DMC) catalyst in a reactor vessel, charging to the reactor vessel a mixture containing two or more alkylene oxides to activate the catalyst, and continuously feeding one or more alkylene oxides to produce the polyether polyol, wherein a 1% solution in water of the polyether polyol has a cloud point of from greater than about 32 DEG C to less than about 53 DEG C, the polyether polyol has a number average equivalent weight of from greater than about 1,000 Da to about 10,000 Da, and a four-hour aerosol inhalation exposure to the polyether polyol has a LC50 of greater than about 5 mg / L. The water-miscible metalworking fluid produced by the inventive process may find use in cooling and / or lubricating metal surfaces during one or more of grinding, cutting, boring, drilling and turning of metal parts.

The invention discloses an intelligent reminding effective aerosol inhalation device for internal medicine nursing. The device comprises a frequency acquisition circuit, a feedback comparison circuitand a filtering emission circuit. The frequency acquisition circuit is used for acquiring analog signal frequency of a controller in the internal medicine nursing intelligent reminding effective aerosol inhalation device. The feedback comparison circuit uses a triode Q1 and a triode Q2 to form a push-pull circuit to prevent signal crossover distortion. Meanwhile, an operational amplifier AR1, a diode D2 and a diode D3 are used for forming a mean value detection circuit to extract mean value signals in signal waveforms, an operational amplifier AR4, a capacitor C4, a capacitor C5 and a capacitor C9 are used for forming a frequency selection circuit to limit the signals, and a capacitor C7, a capacitor C8 and resistors R16-R16 are used for the filtering transmitting circuit. And a resistor R18 forms a filter circuit to filter signal clutters, and the signal clutters are sent to a remote monitoring platform of the aerosol inhalation device through a signal emitter E1, so that the performance of the internal medicine nursing intelligent reminding effective aerosol inhalation device is guaranteed.

The invention discloses a medicine storage and atomizing device for aerosol inhalation administration. The medicine storage and atomizing device for aerosol inhalation administration comprises a medicine cup module, an atomizing module and an isolating component, wherein the medicine cup module comprises a medicine cup; the medicine cup is provided with a cavity for containing liquid medicine; an atomizing opening which communicates with the cavity is formed in the medicine cup; the atomizing module comprises an atomizing piece which is used for atomizing the liquid medicine; the isolating component is positioned between the atomizing opening and the atomizing module and is used for allowing the liquid medicine to be in contact with the atomizing piece only during aerosol administration; when the medicine storage and atomizing device is in an aerosol administration state, the isolating component is drawn, removed or damaged, and the liquid medicine in the medicine cup is in contact with the atomizing piece; the medicine cup module further comprises a first connecting component which is connected with an atomizing equipment main body; and the atomizing module further comprises a second connecting component which is connected with an atomizing mask or a suction nozzle. A cleaning step after atomizing of the medicine is omitted, medicine cross contamination caused by unthorough cleaning is avoided, loss of the atomizing equipment main body is reduced, and the service life of the atomizing equipment main body can be prolonged.

The invention belongs to the technical field of medicines. The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for preventing and treating COVID-19 (diseases caused by novel coronaviruses) and a preparation method thereof. The pharmaceutical composition comprises active ingredients of mycobacterium vaccae for injection and salbutamol sulfate, and the weight ratio of the mycobacterium vaccae for injection to the salbutamol sulfate is 1: (50-200). The medicine prepared from the medicine composition can adopt an aerosol inhalation treatment mode, and through short-term aerosol inhalation, the compliance of a patient can be improved by providing the medicine with a specific purpose for the patient, so that the patient can take the medicine conveniently, and the medical cost is reduced. The pharmaceutical composition for preventing and treating COVID-19 disclosed by the invention has the advantages that the COVID-19 can be effectively prevented and treated; severe or critical symptoms of patients are relieved, nucleic acid negative conversion time is shortened by about 4 days averagely, treatment time is correspondingly shortened, other respiratory virus infections can be prevented and treated nonspecifically, and a new way and scheme are provided for clinical prevention and treatment of COVID-19 and respiratory virus infections.

The invention belongs to a novel multifunctional aerosol inhalation device, which consists of a mouth holder, a T-shaped joint, an extension tube, a liquid cup cover, a liquid cup and a gas connecting tube, wherein the T-shaped joint consists of a transverse tube and a vertical tube; and a liquid adding opening, a gas inlet opening, a one-way valve, an aerial fog generator, a hose and a sand ball. The novel multifunctional aerosol inhalation device can be used for aerosol inhalation, off-line breathing function training and off-line continuous airway humidification of an artificial airway patient and aerosol inhalation treatment of an ordinary patient. In the use process, the novel multifunctional aerosol inhalation device has the following advantages that aerosol inhalation liquid is sealed, so that the severe choking cough caused by reverse entering of the aerosol inhalation liquid into the airway of the patient due to the body position change of the patient cannot occur; the medicine waste can be avoided; the identical effect can be achieved through the rotation of the T-shaped joint; fog drops are filtered by a filter screen, so that a flow rate sensor of a breathing machine is protected; and the hose is positioned in the lowest position of the liquid cup through the sand ball, so that the continuous generation of the gas fog is ensured.

The invention discloses a comprehensive therapy method for serious cold and a special device. The therapy adopts the syndrome differentiation therapeutic principle, the physical therapy, the aerosol inhalation spray inhalation therapy, the traditional Chinese medicine and western medicine treatment are synthetically used and integrated, and the physical therapy with Chinese medicine decreases the gradient temperature gradually owing to the circular cold water. The special equipment comprises a heat water box, a medicine fog generator, an ice pillow, a therapy chamber, an atomization inhaler, a circling water pump, a zone generator, a compressor, a cool water preparation box, a controlling temperature cabinet, a disinfection solution preparation box, a whisker, a waste liquid treatment box, a non-touch typed thermometer, a control system and an operation panel. The invention is characterized in that the therapy chamber is arranged in the middle-upper part of the equipment, and the patient can be cured by the medicine in the therapy chamber.

The invention discloses a multifunctional breather valve. The multifunctional breather valve includes a breather valve body, a pipe, and a patient end interface, a spray gas connection port and an exhaust port arranged in the pipe. A one-directional inhalation valve is arranged in the gas-spray gas connection port. A limit board is arranged in the exhaust port. The limit board is provided with a communication port. An expiration resistance adjusting device is arranged for the communication port. The expiration resistance adjusting device includes a one-direction expiration valve, a reset spring and a resistance adjusting device. According to the invention, spray gas can be inhaled into the lung part fully and is output during the inspiration process synchronously, secreta is discharged timely, the pipe pressure is stable under different pressure levels due to noninvasive mechanical ventilation and lung injury caused by over high airway pressure during the mechanical ventilation process is avoided. The multifunctional breather valve is suitable for serving as a one-direction valve for aerosol inhalation treatment, an exhalation valve for shock sputum excretion and noninvasive mechanical ventilation, a cough pressure relief valve during the mechanical ventilation process and a valve for breath muscle exercise.

The invention discloses a citral submicron emulsion and a preparation method thereof. The preparation method comprises following steps of mixing an emulgator, a co-emulsifier and a stabilizer at 10-30DEG C, stirring uniformly, dripping citral while stirring so as to form an oil phase, and then adding ultrapure water so as to prepare the citral submicron emulsion, wherein the volume ratio of citral to the emulgator to the co-emulsifier to ultrapure water is 1:(0.5-3):(0.25-1):(1.5-5), and the mass dosage of stabilizer is 0.005-0.02g / ml according to the volume dosage of citral. The oil-in-water type submicron emulsion has small particle size, is uniform in particle distribution and has good stability, nasal spraying or aerosol inhalation can promote absorption of the drug and increase local drug concentration, and the citral submicron emulsion can remarkably relieve the syndrome of an asthma rat when being atomized on the rat, thus laying a foundation for clinical application of citral.

The invention relates to an acute bronchitis solution preparation for aerosol inhalation, belonging to the field of pharmaceutics. The acute bronchitis solution preparation for aerosol inhalation comprises (1) acute bronchitis active ingredients, (2) an isotonic agent and a solvent, and also can comprise a buffer solution. The solution preparation prepared by adopting a method provided by the invention makes up the blank of the domestic market at present, and the problem that the preparation medicines specially used for inhalation treatment are not available is solved. The solution preparation prepared by adopting the method provided by the invention is specially designed for aerosol inhalation patients, and is matched with an atomizer for use, the use process is convenient and rapid, compared with acute bronchitis syrup, the acute bronchitis solution preparation has the advantages that the administration route is different, the using dosage is reduced, and the safety is improved.

The invention relates to a jet type aerosol inhalation system realizing intelligent medicine control. The system mainly comprises a core control module (1), a respiratory rate sensor (2), an air flow control switch (3), a delay adjustment device (4), an air source input device (5) and a medical vaporizer (6). The system intelligently controls the output of aerosolized drugs to be synchronous with the respiratory rate of a patient, greatly increases the effective inhalation quantity of the drugs, improves the aerosol treatment effect and avoids waste caused by ineffective aerosol discharging of the drugs, thereby having quite high clinical significance and use value.