The invention relates to an intelligent mine management system and method based on an intelligent mine management and control platform. An operation layer comprises an Internet remote office system, a central management platform, a coal quality production and sale management system, an intelligent unmanned sale system, a one-ventilation and three-prevention management system, a production technology management system, an operation management system and an electromechanical management system; and an execution layer comprises a pressure fan monitoring system, a main conveyor belt monitoring module, a domestic sewage treatment system, a main ventilation system monitoring module, a mine power supply monitoring module, a washing and dressing system, an overhead man-vehicle monitoring system, a boiler thermodynamic system monitoring module, a loading system monitoring module, a production fire-fighting water supply system, a nitrogen injection system monitoring module, a grouting system monitoring module, a driving face automatic monitoring module, a fully mechanized mining face automatic monitoring module and a main drainage automatic monitoring module. The intelligent mine management method matches the intelligent mine management and control platform, and changes traditional coal mine production management, safety management and operation management modes.