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43results about How to "Oral dose is small" patented technology
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Preparation for resisting altitude sickness and application of preparation
InactiveCN105193839APrevent altitude sicknessOvercome side effectsOrganic active ingredientsAntinoxious agentsSubcutaneous injectionIntravenous use
The invention discloses a preparation for resisting altitude sickness and an application of the preparation and relates to the field of medicinal preparations. The preparation for resisting the altitude sickness comprises 0.05-0.2 g of acetazolamide, 10-20 mg of coenzyme Q10, 500-1,000 mg of tyrosine and 1-2 mg of selenium, wherein selenium can be selenium salt and selenium yeast. The preparation is used for preventing altitude sickness symptoms such as headache, insomnia, dyspnea and the like. According to the application, the altitude sickness symptoms can be prevented in multiple drug-delivery ways including subcutaneous injection or intramuscular injection, intravenous injection or intravenous drip, oral administration including pills, capsules, tablets and the like and a nasal drug delivery system such as nasal spray and the like. The preparation has the benefits that the preparation can prevent altitude sickness symptoms such as headache, insomnia, dyspnea and the like, can effectively prevent altitude sickness and can overcome side effects of acetazolamide when the use quantity of the preparations is smaller than a conventional dosage of acetazolamide.
Owner:CHANGZHOU ADAM BIOTECH
Preparation for treating osteoporosis and preparation method thereof
ActiveCN1839999AReduce and relieve soreness symptomsImprove repair effectSkeletal disorderPill deliverySalvia miltiorrhizaDisease
The invention discloses a medicinal capsule for treating urinary system disease and preparation method, wherein the preparation comprises longspur epimedium 7.5-70%, prepared rehmannia root 6-50%, drynaria 5-65%, astragalus root 5-40%, radix salvia miltiorrhiza 5-60%, edible black fungus 3-20%, and cucumber seeds 5-30%.
Owner:LIAONING KANGCHEN PHARMACEUTICAL CO LTD
Antipruritic composite Chinese medicine and its preparing process
ActiveCN101032611AAdvanced technologyFully extractedAerosol deliveryOintment deliveryGypsumSchizonepeta
The present invention relates to one kind of Chinese medicine composition for stopping itching and its preparation process. The Chinese medicine composition is prepared with 13 kinds of Chinese medicinal materials, including schizonepeta herb, flavescent sophora root, angelica, rehmannia root, gypsum, etc. The preparation process is advanced and sufficient in effective component extraction, and the Chinese medicine composition has reliable curative effect, no irritative smell and other advantages.
Owner:LIAONING KANGCHEN PHARMACEUTICAL CO LTD
Self-microemulsifying nanocombination comprising lucid ganoderma total triterpene and jobstears seed oil and preparation method and application thereof
InactiveCN102940813AReduce dosageImprove tumor inhibition rateEmulsion deliveryAntineoplastic agentsTriterpeneAdjuvant
The invention relates to a self-microemulsifying nanocombination comprising lucid ganoderma total triterpene and jobstears seed oil and a preparation method and application thereof. The lucid ganoderma total triterpene and the jobstears seed oil are adopted as medicinal materials, the jobstears seed oil doubles as the oil phase, the mixture of surfactant and cosurfactant is adopted as medicine carrier, and the parts by weight are as follows: 15 parts of lucid ganoderma total triterpene, 45 to 150 parts of jobstears seed oil, 45 to 200 parts of surfactant and 20 to 100 parts of cosurfactant. The invention also discloses the preparation method and application of the self-microemulsifying nanocombination. The invention prepares the self-microemulsifying nanocombination with the water-insoluble medicinal lucid ganoderma total triterpene and the jobstears seed oil, wherein the jobstears seed oil has the effects of both medicine and adjuvant, so that the dosage of preparation adjuvant, and moreover, the jobstears seed oil and the lucid ganoderma total triterpene which are compatible have a synergistic antitumor effect. Meanwhile, the self-microemulsifying nanocombination can promote the absorption of medicines, so that the antitumor effect can be enhanced.
Owner:陈彦
Compound wild kiwi tablet and its preparing method
InactiveCN1857378AAntitumorImprove immunityDigestive systemImmunological disordersMedicineFreeze-drying
The present invention discloses a kind of compound wild kiwi tablet and its preparation process. The compound wild kiwi tablet is prepared with wild kiwi, angelica, astragalus root, tuckahoe, and American ginseng in certain weight proportion, and through decocting, filtering, concentrating filtrate to form extractum, spray drying the extractum, vacuum or vacuum freeze drying, crushing, sieving, mixing with supplementary material, pelletizing, drying, tabletting, and coating. The present invention is one health food with high curative effect and possessing functions of benefiting Qi, nourishing blood and raising immunity. It is suitable for being taken by health people and patients with immunological hypofunction.
Owner:ZHEJIANG UNIV
Compound traditional Chinese medicine extract, as well as preparation method and application thereof
ActiveCN104173505AImprove complianceSave resourcesMetabolism disorderPharmaceutical non-active ingredientsMotherwortPharmacologic action
The invention provides a traditional Chinese medicine extract and a preparation method thereof. The compound traditional Chinese medicine extract is prepared from the following raw medicinal materials in parts by weight: 30-60 parts of astragalus membranaceus, 9-15 parts of glossy privet fruit, 9-30 parts of herba leonuri, 3-10 parts of fructus mume, 2-9 parts of coptis chinensis, 1-5 parts of cinnamon and 3-9 parts of butterflybush flower. The preparation method comprises the following steps: extracting volatile oil from cinnamon, and including the volatile oil by beta-cyclodextrin; extracting the cinnamon residue, astragalus membranaceus, glossy privet fruit, butterflybush flower and fructus mume by an ethanol solution I, and refining by means of macroporous adsorption resin to prepare dried extract powder 1; extracting the coptis chinensis and herba leonuri by an ethanol solution III, and refining by ion-exchange resin to prepare dried extract powder 2; and uniformly mixing the dried extract powder 1, the dried extract powder 2 and the volatile oil inclusion compound to obtain the compound traditional Chinese medicine extract. The preparation method is capable of remarkably improving the bioactive substance content and the pharmacologic action of the compound traditional Chinese medicine extract.
Owner:BEIJING HANDIAN PHARMA CO LTD
Process for extracting active ingredients of American eleutherine rhizome
InactiveCN102670865AImprove complianceQuality improvementCardiovascular disorderPlant ingredientsChemistryDrug action
The invention relates to a process for extracting active ingredients of American eleutherine rhizome. The process includes the steps of crushing, extraction, concentration, extraction, separation and the like and is characterized in that a pyricularia oryzae active screen model is combined for determining the best extraction portion of the active ingredients, and active compounds are separated by means of silica gel column chromatography, medium and low pressure column chromatography, high performance liquid chromatography and the like. The separation and purification process for the effective portion is applicable to a certain scale of production and stable in qualities. The process for extracting the active ingredients of the American eleutherine rhizome is high in efficiency, high in treatment purity of the obtained active ingredients and strong in drug action.
Owner:NANJING MAIDISEN MEDICAL TECH
Oral insulin medicament and preparation method thereof
ActiveCN101590221AImprove bioavailabilityIn line with the physiological internal environmentPeptide/protein ingredientsMetabolism disorderCholic acidTherapeutic effect
The invention relates to an oral insulin medicament for treating type II diabetes, which contains insulin, primary bile acid, lecithin, cholesterol and bilirubin. The oral insulin medicament comprises the following components by weight: 1 weight portion of insulin, 30 to 100 weight portions of primary bile acid, 100 to 300 weight portions of lecithin, 1 to 3 weight portions of cholesterol, 0.08 to 0.8 weight portion of bilirubin, and 50 weight portions of bile acid. The invention prepares the insulin medicament which satisfies physiological characteristics of organisms according to the bionics, and proves the administration of the insulin medicament through an oral way has exact therapeutic effect on the type II diabetes through animal experiments and clinical trials. The medicament satisfies the physiological characteristics of the organisms, can ensure that blood sugar keeps relatively steady within 24 hours without hypoglycemic reaction, can also ensure that the lecithin in bodies of type II diabetic patients is reduced and the metabolic disturbance of the bile acid is gradually corrected when the blood sugar is reduced, and has preventing and treating effect on complicating diseases caused by the type II diabetes.
Owner:江苏平衡生物医药科技有限公司
Hazel leaf flavonoid extract and its pharmaceutical composition
InactiveCN102258547AGood dissolution effectImprove bioavailabilityMetabolism disorderAntinoxious agentsChemistryFlavones
The invention discloses a hazel leaf flavone extract and a medicinal composition thereof. The method for preparing the hazel leaf flavone extract comprises the following steps: 1) pulverizing dried hazel leaf into fine powder; 2) mixing the fine powder and helicase in a weight ratio of 1500:1 or so to obtain an extraction material; 3) filling the extraction material into an extraction kettle, carrying out supercritical carbon dioxide extraction to obtain a mixture, wherein the extraction conditions are as follows: the extraction pressure is 35MPa, the extraction temperature is 48-52 DEG C, the supercritical carbon dioxide flow rate is 37-40kg / h, and the extraction time is 2.0-2.5 hours; and 4) carrying out two-stage separation on the extraction mixture in the step 3 through a reduced pressure separation kettle, thereby obtaining the hazel leaf flavone extract, wherein the primary pressure separation is carried out under the pressure of 7.5MPa or so at the temperature of 45-50 DEG C, and the secondary reduced pressure separation is carried out under the pressure of 5.5MPa at the temperature of 45 DEG C. The invention has the advantages of high extraction yield and high composition dissolution rate.
Owner:HEILONGJIANG UNIV
Preparation method of Chinese herbal extract, prepared Chinese herbal extract and application
ActiveCN104161848AGuaranteed blood sugar effectHypoglycemic effectSenses disorderMetabolism disorderMedicinal herbsMotherwort
The invention provides a preparation method of a Chinese herbal extract and the prepared Chinese herbal extract. Active pharmaceutical ingredients of the Chinese herbal extract comprise, by weight, 30-60 parts of Radix Astragali, 9-15 parts of ligustrum lucidum, 9-30 parts of motherwort, 3-10 parts of dark plum, 2-9 parts of coptis, 1-5 parts of cortex cinnamomi and 3-9 parts of Buddleja officinalis. The preparation method comprises the following steps: extracting volatile oil from cortex cinnamomi, and carrying out clathration on the volatile oil with beta-cyclodextrin; extracting cortex cinnamomi herbal residue and other medicinal materials with 30%-80% (by volume) of an ethanol solution; and refining an extract by passing through macroporous resin and drying to obtain a dry extract powder, adding a volatile oil clathrate, and uniformly mixing. By the preparation method, active material content and pharmacological action of the Chinese herbal extract are boosted remarkably.
Owner:BEIJING HANDIAN PHARMA CO LTD +1
Extraction technology of active component from red onions
InactiveCN104628791AImprove complianceQuality improvementOrganic chemistryPyriculariaColumn chromatography
The invention relates to an extraction technology of active component from red onions. The extraction technology comprises main steps of pulverizing, extracting, condensing, extracting, and separating; and is characterized in that a pyricularia oryzae activity screening mode is used to assist the extraction technology so as to determine the optimal extraction part for active component extraction, and the active components are separated by silica gel column chromatography, medium-low pressure column chromatography, high performance liquid chromatography (HPLC), and the like. The provided extraction technology can be applied to massive production of active components with a stable quality from effective parts of red onions. The extraction technology has a high efficiency, and the obtained active component has the advantages of high purity and strong pharmaceutical effect.
Owner:QINGDAO ZHONGREN ZHIYE BIOTECH
Chicken gallbladder extractum dispersible tablet and its preparation process
InactiveCN1628699AEasy to prepareQuality improvementAntibacterial agentsUnknown materialsDiluentDispersible tablet
The invention discloses a chicken gallbladder extractum dispersible tablet and its preparation process, wherein the raw materials for preparing the chicken gallbladder extractum dispersible tablet comprises chenodeoxycholanic acid, coating agent, diluent, crumbling agent, binding agent, lubricating agent, flavoring agent.
Owner:吉林省七星山药业有限公司
Oral insulin medicine and preparation method thereof
ActiveCN100594929COral dose is smallFree from painPeptide/protein ingredientsMetabolism disorderCholic acidTherapeutic effect
The invention relates to an oral insulin medicament for treating type II diabetes, which contains insulin, primary bile acid, lecithin, cholesterol and bilirubin. The oral insulin medicament comprisesthe following components by weight: 1 weight portion of insulin, 30 to 100 weight portions of primary bile acid, 100 to 300 weight portions of lecithin, 1 to 3 weight portions of cholesterol, 0.08 to0.8 weight portion of bilirubin, and 50 weight portions of bile acid. The invention prepares the insulin medicament which satisfies physiological characteristics of organisms according to the bionics, and proves the administration of the insulin medicament through an oral way has exact therapeutic effect on the type II diabetes through animal experiments and clinical trials. The medicament satisfies the physiological characteristics of the organisms, can ensure that blood sugar keeps relatively steady within 24 hours without hypoglycemic reaction, can also ensure that the lecithin in bodies of type II diabetic patients is reduced and the metabolic disturbance of the bile acid is gradually corrected when the blood sugar is reduced, and has preventing and treating effect on complicating diseases caused by the type II diabetes.
Owner:江苏平衡生物医药科技有限公司
Extraction process for novel anti-diabetes traditional Chinese medicine allium macrostemon or effective fraction
InactiveCN103908559AThe mechanism of action is clearNovel Chemical ComponentsMetabolism disorderSteroidsPatient complianceCombined method
A purpose of the present invention is to provide a purification process for a traditional Chinese medicine allium macrostemon or an effective fraction, wherein the purification process has characteristics of stable quality and simple route, and is suitable for large-scale production. According to the present invention, the natural medicinal chemistry and molecular pharmacology combined method is adopted to study the diabetes treatment effect of the traditional Chinese medicine allium macrostemon and the effective substance basis in the field of cardiovascular protection, and determine the structure, the characteristic and the activity of the macrostemonoside compound and the like, and the new active components can be produced through compatibility of different proportions of monomers; and the extraction process has characteristics of simpleness, easily available raw materials, low cost and high extraction rate, and is suitable for large-scale industrial production, and advantages of easy drug quality control, low oral dose, high patient compliance and the like are provided.
Owner:NANJING DINGYE BIOPHARM IND GRP
Traditional Chinese medicine multicomponent micro-emulsion composition having function of resisting lung cancer, preparation method and application thereof in preparation of orally-taking lung cancer resistant medicine
ActiveCN102961417ASimple preparation processEasy to industrializeEmulsion deliveryEster active ingredientsSolubilitySemen
The invention discloses a traditional Chinese medicine multicomponent micro-emulsion composition having a function of resisting lung cancer, a preparation method and application thereof in preparation of an orally-taking lung cancer resistant medicine. The application comprises the following steps of: adding ganoderma lucidum total triterpenes, coixenolide, ganoderan and semen coicis polysaccharide used as raw material medicines into a nano-medicine composition which consists of surfactants and cosurfactant, wherein the traditional Chinese medicine multicomponent micro-emulsion composition comprises the following components in parts by weight: 5-30 parts of ganoderma lucidum total triterpenes, 45-150 parts of coixenolide, 5-50 parts of ganoderan and 10-90 parts of semen coicis polysaccharide, 45-200 parts of surfactants, 20-100 parts of cosurfactant and 300-900 parts of distilled water. The invention also discloses a preparation method of the composition. The ganoderma lucidum total triterpenes and the coixenolide are carried into a non-water phase, and the lucid ganoderma and the semen coicis polysaccharide are carried into a water phase, so that the coixendide can be used as medicines and also can be used as an auxiliary; the polysaccharide can enhance the immunization and the stability of a micro-emulsion system; and by the micro-emulsion, the absorption of the ganoderma lucidum total triterpenes and coixenolide used as the lipid solubility components can be increased, and the matching of four components have a synergy anti-tumor effect so as to increase the anti-tumor effect.
Owner:陈彦
Traditional Chinese medicinal tablet for curing diabetic retinopathy and application thereof
ActiveCN104161849AImprove complianceSave resourcesMetabolism disorderPill deliveryDiabetes retinopathyMotherwort
The invention relates to a traditional Chinese medicinal tablet for curing diabetic retinopathy and an application thereof. A traditional Chinese medicinal tablet is provided. Raw medicines of the traditional Chinese medicinal tablet comprise, by weight, 30-60 parts of Radix Astragali, 9-15 parts of ligustrum lucidum, 9-30 parts of motherwort, 3-10 parts of dark plum, 2-9 parts of coptis, 1-5 parts of cortex cinnamomi and 3-9 parts of Buddleja officinalis. The traditional Chinese medicinal tablet is prepared by the following method: extracting volatile oil from cortex cinnamomi, and carrying out clathration on the volatile oil with beta-cyclodextrin; extracting cortex cinnamomi herbal residue, Radix Astragali, ligustrum lucidum, Buddleja officinalis and dark plum with an ethanol solution I, and refining with macroporous resin to obtain a dry extract powder 1; extracting coptis and motherwort with an ethanol solution III, and refining with ion exchange resin to obtain a dry extract powder 2; and adding auxiliary materials which are pharmaceutically acceptable into the dry extract powder 1, the dry extract powder 2 and a volatile oil clathrate, and carrying out tabletting to obtain the traditional Chinese medicinal tablet. In comparison with the prior art, the tablet provided by the invention has higher active material content in a unit preparation and has better pharmacological action.
Owner:BEIJING HANDIAN PHARMA CO LTD +1
Traditional Chinese medicine for treating lung cancers and application thereof
InactiveCN106177679AEffective treatmentOral dose is smallHydroxy compound active ingredientsPharmaceutical delivery mechanismBULK ACTIVE INGREDIENTCommon Anemarrhena Rhizome
The invention provides a traditional Chinese medicine for treating lung cancers. The traditional Chinese medicine comprises the following active ingredients in parts by weight: 100-150 parts of Chinese angelica, 100-150 parts of Chinese gentian, 10-15 parts of amur corktree bark, 10-20 parts of cape jasmine fruit, 10-20 parts of baical skullcap root, 3-8 parts of aloes, 3-8 parts of natural indigo, 3-8 parts of rhubarb, 7-12 parts of costustoot, 3-8 parts of amur corktree bark, 3-8 parts of radix codonopsis, 2-6 parts of red paeony root, 1-5 parts of figwort root, 2-6 parts of coastal glehnia root, 1-5 parts of dwarf lilyturf tuber, 3-8 parts of common anemarrhena rhizome, 3-8 parts of stem of noble dendrobium, 1-4 parts of fresh root of woods greenstar and 1-5 parts of fresh sessile stemona root. Compared with the prior art, the traditional Chinese medicine has good anticancer activity and can be used as an anticancer medicine. The traditional Chinese medicine composition is simple to prepare, is basically nontoxic, is accessible in raw materials, is suitable for mass use and has a good application prospect.
Owner:TIANJIN HESHENG MEDICAL TECH DEV
Oral medicament combination of carbamazepine
InactiveCN101711739BGood dissolution effectImprove bioavailabilityNervous disorderEmulsion deliverySoftgelHard Capsule
The invention relates to an oral medicament combination of carbamazepine, containing at most 10% of carbamazepine, and a proper amount of oil, surface active agents, assistant surface active agents and supersaturated matter. The invention also provides a preparation containing the medicament combination, in particular to a soft capsule or a hard capsule. The oral medicament combination of carbamazepine in the invention has high bioavailability so that the oral dosage of the carbamazepine is reduced, and the toxic and side effects are reduced to a certain degree.
Owner:INST OF PHARMACOLOGY & TOXICOLOGY ACAD OF MILITARY MEDICAL SCI P L A
Aloe haw ball and preparation method thereof
ActiveCN110050972ALess irritatingOral dose is smallHydrolysed protein ingredientsDigestive systemIrritationSubstance content
The invention discloses an aloe haw ball and a preparation method thereof. The aloe haw ball includes, by weight, 2-4 parts of hawthorn fruit, 0.5-1.5 parts of aloe powder, 2-4 parts of honey and 0.05-0.15 part of senna leaf extract. By means of the combination of the aloe and the senna leaf extract, the two raw materials which are originally irritating substances become relatively moderate underthe harmony of the hawthorn fruit and the honey, and the irritation to the body is greatly reduced. The efficacy of the two raw materials is synergistic and can achieve a better effect under the low content to reduce the oral doses. Therefore, the beneficial technical advantages can be achieved, and the problems in the prior art of poor effects and strong gastrointestinal dependence due to low effective substance content of the senna leaf are solved.
Owner:周黎明
Abiraterone ester derivatives as well as preparation method and application thereof
PendingCN113929727AIncrease fat solubilityAvoid first pass effectOrganic active ingredientsUrinary disorderAbirateronePharmaceutical drug
The invention relates to abiraterone ester derivatives represented by a general formula I, a pharmaceutical composition containing the abiraterone ester derivatives and an application of the abiraterone ester derivatives and the pharmaceutical composition to treatment and / or prevention of tumors. The groups in the formula are defined in the specification.
Owner:南京易腾药物研究院有限公司
Antipruritic composite Chinese medicine and its preparing process
The present invention relates to one kind of Chinese medicine composition for stopping itching and its preparation process. The Chinese medicine composition is prepared with 13 kinds of Chinese medicinal materials, including schizonepeta herb, flavescent sophora root, angelica, rehmannia root, gypsum, etc. The preparation process is advanced and sufficient in effective component extraction, and the Chinese medicine composition has reliable curative effect, no irritative smell and other advantages.
Owner:LIAONING KANGCHEN PHARMACEUTICAL CO LTD
Compound wild kiwi tablet and its preparing method
InactiveCN100455300CAntitumorImprove immunityDigestive systemImmunological disordersFreeze-dryingMedicine
The present invention discloses a kind of compound wild kiwi tablet and its preparation process. The compound wild kiwi tablet is prepared with wild kiwi, angelica, astragalus root, tuckahoe, and American ginseng in certain weight proportion, and through decocting, filtering, concentrating filtrate to form extractum, spray drying the extractum, vacuum or vacuum freeze drying, crushing, sieving, mixing with supplementary material, pelletizing, drying, tabletting, and coating. The present invention is one health food with high curative effect and possessing functions of benefiting Qi, nourishing blood and raising immunity. It is suitable for being taken by health people and patients with immunological hypofunction.
Owner:ZHEJIANG UNIV
A traditional Chinese medicine capsule for treating diabetic retinopathy and its application
ActiveCN104173504BOral Dose GuaranteedOral dose is smallMetabolism disorderPharmaceutical non-active ingredientsDiabetes retinopathySmoked Plum
The invention provides a traditional Chinese medicine capsule for treating diabetic retinopathy and an application of the traditional Chinese medicine capsule for treating diabetic retinopathy. The traditional Chinese medicine comprises the following raw materials in parts by weight: 30 to 60 parts of astragalus membranaceus, 9 to 15 parts of glossy privet fruit, 9 to 30 parts of leonurus, 3 to 10 parts of smoked plum, 2 to 9 parts of coptis chinensis, 1 to 5 parts of cortex cinnamomi and 3 to 9 parts of butterflybush flower. The preparation method of the capsule comprises the following steps: extracting a volatile oil from the cortex cinnamomi and enveloping the volatile oil with Beta-cyclodextrin; extracting medicinal residues of the cortex cinnamomi and the rest of medicinal materials by virtue of an ethanol solution with the volume percentage concentration of 30% to 80%; refining an extract with macroporous adsorption resin and drying so as to obtain dry extract powder; adding a volatile oil clathrate into the dry extract powder, evenly mixing, adding pharmaceutically acceptable auxiliary materials and filling into a capsule so as to obtain the traditional Chinese medicine capsule. Compared with the prior art, the content of active substances in the traditional Chinese medicine capsule provided by the invention is obviously improved, so that the obvious pharmacologic action of the traditional Chinese medicine capsule provided by the invention is achieved.
Owner:BEIJING HANDIAN PHARMA CO LTD +1
A preparation method of Chinese medicine compound extract and the prepared Chinese medicine compound extract and application thereof
ActiveCN104173505BImprove complianceSave resourcesMetabolism disorderPharmaceutical non-active ingredientsBiotechnologyMotherwort
Owner:BEIJING HANDIAN PHARMA CO LTD
A traditional Chinese medicine tablet for treating diabetic retinopathy and its application
ActiveCN104161849BImprove complianceSave resourcesMetabolism disorderPill deliveryBerberineDiabetes retinopathy
Owner:BEIJING HANDIAN PHARMA CO LTD +1
Pyrazolopyrimidinone derivatives for the treatment of impotence
InactiveCN1136219CIn vivo effect is goodOral dose is smallOrganic active ingredientsOrganic chemistrySide effectMedicine
The present invention relates to pyrazolopyrimidinone derivatives of formula (1), their preparation method and pharmaceutical compositions containing the said derivatives. The compounds have efficacy on the treatment of impotence, one of male sexual dysfunctions with the side effects reduced.
Owner:东亚制药技术株式会社
Blood fat-lowering and liver-protecting composite as well as preparation prepared thereby and preparation method of preparation
InactiveCN102008598BSimple componentsActive ingredient clearMetabolism disorderDigestive systemPhenolic content in teaOfficinal
The invention provides a blood fat-lowering and liver-protecting composite as well as a preparation prepared thereby and a preparation method of the preparation, belonging to the technical field of traditional Chinese medicines. At present, in Chinese material medical preparations with the effects of lowering blood fat and protecting liver, most of the Chinese material medical preparations are costly prescription and has complicated components and backward process, contains nutritious components, and increases the load of the liver due to excessive components. The blood fat-lowering and liver-protecting composite provided by the invention comprises the following raw materials in parts by weight: 90-130 parts of pseudo-ginseng and 30-70 parts of tea. The preparation prepared from the composite comprises active ingredients and pharmaceutic adjuvants, wherein the active ingredients comprise the following components in parts by weight: 4-13 parts panax notoginseng saponins (PNS) and 2-8 parts of tea polyphenol (TP). The blood fat-lowering and liver-protecting composite and the preparation provided by the invention have the advantages of clear active ingredients, good stability, controllable quality and less dosage, and are convenient to use and carry.
Owner:SHENZHEN INST OF TECH
Post-ahypnia headache medicine and preparation method thereof
InactiveCN108671102AReduce lossNo side effectsNervous disorderPharmaceutical non-active ingredientsLigusticum chuanxiongSide effect
The invention discloses an ahypnia headache medicine and a preparation method of the medicine, and relates to a medicine for treating an ahypnia headache and a preparation method of the medicine. Themedicine solves the technical problems that the existing method for treating the post-ahypnia headache has a non-ideal medication effect, and especially, a western medicine has side effects of hypersomnia, dizziness and digestive disorders after long-term administration. The medicine comprises radix rehmanniae recen, Chinese angelica, spina date seeds, semen platycladi, polygala roots, rhizoma acori graminei, ligusticum wallichii and radix paeoniae alba. The preparation method comprises the steps of mixing the ligusticum wallichii, the spina date seeds, the Chinese angelica, the rhizoma acorigraminei, the semen platycladi and water for distillation and extraction, preparing a beta cyclodextrin inclusion compound, mixing and decocting decoction dreg after distillation with the radix rehmanniae recen, the radix paeoniae alba and the polygala roots, mixing a residual aqueous solution after the distillation with filtrate, performing pressure reduction concentration, standing, cooling to aroom temperature, adding ethanol, performing uniform mixing, refrigeration, filtration, pressure reduction, drying and grinding, and adding the beta cyclodextrin inclusion compound. The medicine hasan effective rate of 94.30% for treating the post-ahypnia headache, the hypersomnia, the dizziness and the digestive disorders do not occur, and a recurrence rate is less than 26%.
Owner:HEILONGJIANG ACAD OF TCM
Preparation method of medicine capable of moistening dryness and relieving itching
InactiveCN110585299AImprove complianceOral dose is smallCapsule deliveryDermatological disorderFiltrationLaportea bulbifera
The invention discloses a preparation method of a medicine capable of moistening dryness and relieving itching. The raw materials of the medicine consist of traditional Chinese medicine materials of 50-300 parts of prepared polygonum multiflorum root tubers, 80-350 parts of polygonum multiflorum root tubers, 300-500 parts of unprepared rehmannia glutinosa root tubers, 80-350 parts of sophora flavescens roots, 80-350 parts of morus alba leaves and 50-200 parts of laportea bulbifera herbs. The preparation method comprises the steps of (1) taking the polygonum multiflorum root tubers, the prepared polygonum multiflorum root tubers and beta-CD, enabling the polygonum multiflorum root tubers, the prepared polygonum multiflorum root tubers and the beta-CD to dissolve in water, performing soaking, performing reflux extraction, performing concentrating to obtain an extracting solution, and performing spray drying to obtain spray dried powder 1 for standby application; and (2) adding water to the remaining four medicinal materials of the unprepared rehmannia glutinosa root tubers, the morus alba leaves and the like, performing soaking, performing decoction, performing filtration, performingconcentrating to obtain an extracting solution, performing spray drying to obtain spray dried powder 2, uniformly mixing the spray dried powder 2 with the spray dried powder 1 obtained through extraction and concentration of the polygonum multiflorum root tubers and the prepared polygonum multiflorum root tubers, and performing loading into capsules so as to obtain the medicine.
Owner:GUOYAOJITUAN TONGJITANG (GUIZHOU) PHARMA CO LTD
Capsule composition for treating gastric ulcer and duodenal ulcer and preparation method of capsule composition
InactiveCN103735992AQuality improvementOral dose is smallDigestive systemCapsule deliveryDuodenal ulcerGLYCYRRHIZA EXTRACT
The invention provides a capsule composition for treating gastric ulcer and duodenal ulcer and a preparation method of the capsule composition, aiming at overcoming the shortage of the prior art. The capsule composition comprises the following raw materials in parts by weight: 18 to 22g of liquorice, 18 to 22g of pueraria flower, 18 to 22g of radix puerariae, 18 to 22g of fructus amomi, 18 to 22g of galangal, and 13 to 17g of radix paeoniae alba. The capsule composition is in a form of a capsule finally. The preparation method comprises the following steps of purifying at three times; concentrating; preparing dry powder; granulating and filling into a capsule; sterilizing; and warehousing. The capsule composition has the effects of strengthening spleen and invigorating Qi, strengthening mid-energy and harmonizing stomach, regulating vital energy and eliminating distension, relieving for stopping pain, and clearing heat and removing toxicity. The capsule composition is stable in quality, small in dose for taking orally, convenient to take, fast to absorb, high in bioavailability, and simple in production process.
Owner:河南海丝克生物科技股份有限公司
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