The invention relates to a
rare earth doped
gadolinium-
potassium fluoride nanometer material for a
magneto-optical double-module biological marker and a preparation method thereof. The preparation method comprises the following steps of: mixing
gadolinium chloride,
potassium chloride and
ammonium fluoride in
distilled water,
ethanol and ethanediol by utilizing propylene
imine as a surface
active agent; carrying out hydro-
thermal treatment at 50-230 DEG C for a period of time; washing, and
drying to obtain a DGdF4:Ln nanometer
crystal, wherein the commonest of the DGdF4:Ln nanometer
crystal are as follows: xLn3+-(1-x)KGdF4 (Ln=Ce, Pr, Nd, Pm, Sm, Eu, Tb, Dy, Ho, Er, Tm, Yb; x=0-60 mol%). The
rare earth doped DGdF4 nanometer
fluorescence marker material prepared by adopting the method can not only control the size of nanometer granules at about 25 nanometers, but also has better water
solubility, can utilize the amino on the surface to be connected with biological molecules; besides, the biological connection is subjected to hypersensitivity detection by realizing needed
specific fluorescence emission in such a way that different
rare earth ions are doped in the nanometer granules, namely the rare earth doped DGdF4 nanometer
fluorescence marker material obtained through the preparation method has potential in being applied in the field of biological markers; and because
gadolinium ions are contained in a matrix, the DGdF4 nanometer
crystal can be further used as a T1
magnetic resonance imaging contrast agent.