The invention discloses an intelligent drug box system which comprises a drug box composed of a drug box body and a box cover. Two portions including a drug storage chamber and a control chamber are formed in the drug box body, at least one drug bin is arranged in the drug storage chamber, a detection device arranged in the drug storage chamber in a semi-inverted-conical manner is arranged at the bottom of each drug bin and used for detecting conditions of drugs in the drug box body, and a light-emitting device is arranged at the bottom of each drug bin. A controller, a control button, a sounding device, a vibrating device and a position balance sensor are arranged in the control chamber, a central control chip is integrated on the controller, and connection of the drug box and an intelligent terminal is realized through wireless data transmission. By the intelligent drug box system, a user can effectively know the conditions of the drugs in the drug box, a medicine-taking time can be easily set, the user can be accurately and effectively reminded, recording of medicine-taking states and replenishing of new drugs can be conveniently and timely realized, and the problem that the user forgets to carry the emergency drug box can be solved through a binding function.