36results about How to "Moderate polarity" patented technology

The invention discloses a method for detecting seven prohibited compounds in flavors and fragrances. The seven prohibited compounds are methanol, sec-butyl alcohol, safrole, imidazole, coumarin, musk xylene and sesamol. The detection method can accurately and rapidly detect the contents of the seven prohibited compounds in flavors and fragrances, is suitable for quality safety control of fragrance raw liquid and auxiliary solvents in the industries such as food, daily-use chemical industry, tobacco and pharmacy, and the has the characteristics of simple operation, rapidness, accuracy, good repeatability, high sensitivity and the like.

The invention discloses a method for removing diglyceride in medium-and-long-chain-structure ester. The method includes following steps: taking alumina to fill a chromatographic column through a dry process, and taking medium-and-long-chain-structure ester raw material to load the chromatographic column, wherein a mass ratio of the medium-and-long-chain-structure ester raw material to alumina is 1:3-10; using normal hexane-ethyl ether for elution, and collecting elution fraction, wherein a volume ratio of normal hexane to ethyl ether is 19-4:1; using normal hexane-ethyl ether for elution, andcollecting elution fraction, wherein a volume ratio of normal hexane to ethyl ether is 29-14:1; combining the elution fraction with sample column-loading elution fraction, depressurizing for concentration to dryness, vacuum drying, weighing, using a sealing film for sealing, and storing at a dark place. The method realizes effect of removing diglyceride through one-step adsorption and is simple inprocess, low in cost and high in purity of obtained products; alumina has higher adsorption ability and better adsorption effect on two isomesides of diglyceride, and the problem that diglyceride adsorbed by silica gel can be desorbed by fraction with higher polarity in the medium-and-long-chain-structure ester is solved effectively.

The invention provides to a high temperature resistant forming agent and a preparation method thereof, which relate to the technical field of tertiary oil recovery of an oil field. The high temperature resistant forming agent is generated through the copolymerization of 6-acrylamicarboxylic acid, sodium methallyl sulfonate and 1-acryl oxide-2-pyrrolidone. The preparation method of the high temperature resistant forming agent includes the following steps: adding the sodium methallyl sulfonate and an initiator persulfate into a flask, performing magnetic stirring, and mixing the 6-acrylamicarboxylic acid and the 1-acryl oxide-2-pyrrolidone and adding a liquid dripping pump; after the temperature rises to 30 DEG C; injecting the 6-acrylamicarboxylic acid and 1-acryl oxide-2-pyrrolidone mixture into the flask, rising the temperature to 70 DEG C, after heat preservation, and adding a quinone polymerization inhibitor and then stopping the polymerization reaction, and after the reaction is stopped for 20-60 min, cooling to room temperature, and obtaining the high temperature resistant forming agent after separation and purification. According to the invention, the oil field recovery rateis improved under the environment of hot water, steam and high temperature flue gases.

The invention discloses a method for preparing high-purity pseudo-polymorphic lavo-ofloxacin hemihydrate. The existing method adopts organic solvents with over-strong polarity and over-weak polarity to purify a crude lavo-ofloxacin product so as to be not beneficial to the quality and the recovery rate of a finished lavo-ofloxacin hemihydrate product. The organic solvents have higher boiling points, consume more energy when being recovered and are difficult to recover. Under a heating condition, the crude lavo-ofloxacin product is dissolved in a mixed solvent system consisting of two or more solvents, wherein one solvent in the solvent system is water accounting for 2-25 percent of total weight of the solvent system. A counter solvent is added to crystallize by cooling or during cooling, and an obtained crystallized product is dried to prepare the high-purity pseudo-polymorphic lavo-ofloxacin hemihydrate with a single crystalline form. The mixed solvent containing water and having moderate polarity, low boiling point, easy recovery and small energy consumption is adopted by the method, thus the purity of the product is high, and the bioavailability of the lavo-ofloxacin hemihydrate preparation is high after the lavo-ofloxacin hemihydrate preparation is taken by a person.

The invention relates to a continuous extraction method of pepper oil resin, and belongs to the technical field of natural pepper oil resin extraction. The continuous extraction method of the pepper oil resin includes the process steps: crushing pepper and extracting essential oil from the crushed pepper; pretreating pepper powder after essential oil extraction; performing continuous extraction onthe pretreated pepper powder through extraction solution by a rotocel extractor to obtain pepper oil resin extracting solution; continuously concentrating the pepper oil resin extracting solution andremoving solvents to obtain the pepper oil resin. The extraction solution is mixed solution of extraction solvents, diluting solvents and stabilizers. The continuous extraction method of the pepper oil resin can realize continuous extraction, continuous concentration and solvent removal of the pepper oil resin, is good in extraction effect, high in effective component content, less in extractionsolvent dosage, high in automation degree and low in production and can realize large-scale industrial production.

The invention discloses a preparation method for tobacco absolute oil. The preparation method is performed with the following devices: an ultrasonic extraction tank (1), a chromatography column (2), an air compressor (3), a concentration tank (4), a reverse resin column (5), a condenser (6), a vacuum pump (8) and a solvent recovery tank (7). The preparation method comprises the following steps: 1,subjecting a tobacco raw material to ultrasonic extraction; 2, carrying out purification through the chromatography column (2); 3, carrying out concentration; 4, carrying out purification through thereverse resin column ( 5); and 5, carrying out decompressing to remove ethanol so as to obtain the tobacco absolute oil. The devices provided by the invention can realize highly-efficient extractionand purification of the tobacco absolute oil; and the tobacco absolute oil obtained by using the preparation method provided by the invention is used in cigarettes, electronic cigarettes or heat-not-burn cigarettes, and effectively enhances and improves the suction comfort of the cigarettes, the electronic cigarettes and the heat-not-burn cigarettes.

The invention discloses a preparation method of coffee purified oil. The following devices are used: an ultrasonic extraction tank (1), a chromatographic column (2), an air compressor (3), a concentrating tank (4), a reverse resin column (5), a condenser (6), a vacuum pump (8) and a solvent recycling tank (7). The preparation method comprises the following steps: (1) ultrasonically extracting coffee raw materials; (2) purifying through the chromatographic column (2); (3) concentrating; (4) purifying through the reverse resin column (5); and (5) removing ethanol under reduced pressure to obtainthe coffee purified oil. The coffee purified oil can be effectively extracted and purified by the device, the obtained coffee purified oil is used for cigarettes, electronic cigarettes or cigarettesnot combusting after being heated, and the smoking comfort level is effectively improved.

Described is a novel process for fractionating biomass pyrolysis oil quantitatively into energy dense hydrophobic aromatic fraction and water-soluble organics in an economical and energy efficient manner. Using the concepts of solvents and anti-solvent behaviours to separate the pyrolysis oil, which is an emulsion, a method utilising minimal quantities of solvents and water is proposed, By comparison with the existing methods to isolate the hydrophobic aromatic fraction, there is a volume reduction of greater than 50:1. Additionally, there is a significant time saving over the 24 hours for the accepted method as a solvent, and the anti-solvent system is pontaneous.

The invention relates to a binary polymer diesel pour point depressant, and a preparation method and an application thereof. The preparation method for the diesel pour point depressant comprises the following steps: 1) adding methacrylic acid, higher alcohol and a polymerization inhibitor into a solvent, carrying out heating to 55-65 DEG C until the methacrylic acid, the higher alcohol and the polymerization inhibitor are fully dissolved, then adding a catalyst, and carrying out a catalytic reaction; 2) adding cyclohexylamine into triethylamine, then carryin gout heating to 55-65 DEG C, then adding methacryloyl chloride, and carrying out a reaction for 1-3 hours; and 3) adding high-carbon methacrylate and N-cyclohexylmethacrylamide into the solvent, then adding an initiator, and carrying out a polymerization reaction. Compared with the prior art, the binary polymer diesel pour point depressant provided by the invention has novel structure, can effectively improve the low-temperature flowing property of diesel, has good effect in the aspect of lowering a condensation point and a cold filter plugging point, and can enable the condensation point to be lowered by 10-18 DEG C and the cold filter plugging point to be lowered by 0-9 DEG C.

The invention discloses a composite material with gradient melting points, and applications thereof in reinforcing of excavation site antiques. The composition material is a mixed material with gradient melting points and controllable volatility and prepared by mixing one or more components of p-tert-butylcyclohexanol, coumarin ethyl maltol with menthol, and the application limit of the original single temporary reinforcement material can be overcome. A method of the composition material to temporarily reinforce the antiques comprises the following steps: heating and melting the composite material or dissolving the composite material into an organic solvent, to obtain a reinforcement solution; covering a fiber fabric on the to-be-reinforced antiques, sprinkling or coating the prepared reinforcement solution onto the fiber fabric, or directly coating the reinforcement solution onto the reinforcement solution; volatilizing the organic solvent in the reinforcement solution, cooling and solidifying to realize the temporary reinforcement of the antiques. The composite material has the advantages of gradient melting points and controllable volatility, retains the sublimation characteristics and is easily removed from reinforcement parts.

The invention discloses a preparation method of red jujube clean oil, which uses the following devices: an ultrasonic extraction tank (1); a chromatographic column (2); an air compressor (3); a thickening tank (4); a reverse resin column (5); a condenser (6); a vacuum pump (8); a solvent recovery tank (7). The method includes the steps of (1) ultrasonic extraction of red jujube raw material; (2),purifying by chromatographic column; (3); concentration; (4) purifying by a reverse resin column; (5) removing ethanol under reduced pressure to obtain the pure red jujube oil. The device of the invention can efficiently extract and purify the red jujube clean oil, and the obtained red jujube clean oil can be used in cigarette, electronic cigarette or heated non-combustible cigarette, so as to effectively improve and improve the smoking comfort of the cigarette.

The invention discloses a preparation method for dried orange peel absolute oil. The preparation method is performed with the following devices: an ultrasonic extraction tank (1), a chromatography column (2), an air compressor (3), a concentration tank (4), a reverse resin column (5), a condenser (6), a vacuum pump (8) and a solvent recovery tank (7). The preparation method comprises the followingsteps: 1, subjecting a dried orange peel raw material to ultrasonic extraction; 2, carrying out purification through the chromatography column (2); 3, carrying out concentration; 4, carrying out purification through the reverse resin column ( 5); and 5, carrying out decompressing to remove ethanol so as to obtain the dried orange peel absolute oil. The devices provided by the invention can realize highly-efficient extraction and purification of the dried orange peel absolute oil; and the dried orange peel absolute oil obtained by using the preparation method provided by the invention is usedin cigarettes, electronic cigarettes or heat-not-burn cigarettes, and effectively enhances and improves the suction comfort of the cigarettes, the electronic cigarettes and the heat-not-burn cigarettes.

The invention discloses a method for synthesizing 4,5-diphenyl-1,4,5-trihydro-1,2,3-triazole. The method comprises the following steps of firstly mixing 1,2-diphenyl-acrylonitrile, potassium carbonate, sodium azide, cuprous iodide and dimethyl sulfoxide DMSO, stirring and heating to 95-105 DEG C, reacting for 3-3.5 hours, after the reaction is completed, adding water to obtain a mixture, extracting the mixture, distilling to remove the solvent, purifying the residue by column chromatography to obtain 4,5-diphenyl-1,4,5-trihydro-1,2,3-triazole, wherein the feeding molar ratio of 1,2-diphenyl-acrylonitrile, potassium carbonate, sodium azide and cuprous iodide is 1:2:2:0.2. The reaction time and the reaction temperature adopted in the invention are more suitable reaction time and temperature, too high temperature, the ratio of reaction byproducts too high, if the temperature is too low, the reaction cannot be carried out; if the reaction time is shortened, the incomplete reaction can be caused and the reaction time is prolonged, the yield of the byproducts is high.

The invention belongs to the technical field of solid beverages, and particularly relates to a method for preparing dogwood alcohol extract particles. The method comprises the following steps: (1) dogwood dry fruit powder is uniformly mixed with 70-85% (v / v) of a water-alcohol solution according to the ratio of 1 g:(25-40) mL to obtain a suspension; (2) the suspension is ultrasonically extracted and then subjected to residue-liquid separation, and an alcohol extraction filtrate is retained; (3) the alcohol extraction filtrate is subjected to macroporous resin purification treatment; and (4) modified soyabean lecithin and alpha-cyclodextrin are added into the purified alcohol extraction filtrate, and through stirring, homogenizing and spray drying, the dogwood alcohol extract particles areobtained, wherein the using amount ratio of the modified soyabean lecithin to the alpha-cyclodextrin to filter residue or the dogwood dry fruit powder is (0.002 to 0.005):(0.05 to 0.09):1. The alcoholextraction filtrate is subjected to macroporous resin adsorption and purification, so that the content of ursolic acid in the dogwood alcohol extract particles is greatly increased.

The invention discloses a preparation method of rose absolute oil. The following devices are used: an ultrasonic extraction tank (1); a chromatography column (2); an air compressor (3); a concentration tank (4); a reverse resin column (5); a condenser (6); a vacuum pump (8); and a solvent recovery tank (7). The method comprises the following steps: 1) performing ultrasonic extraction of a rose rawmaterial; 2) performing purification by the chromatography column (2); 3) performing concentration; 4) performing purification by the reverse resin column (5); and 5) removing ethanol under reduced pressure to obtain the rose absolute oil. The device of the invention can efficiently extract and purify the rose absolute oil, and the obtained rose absolute oil is used in the cigarettes, the electronic cigarettes or the heat-not-burn cigarettes, and can effectively improve the smoking comfort.

The invention discloses a proton-triggered nano-drug system with hydrophilic-hydrophobic-dimensional double conversion characteristics and a preparation method and application thereof. The system is formed by self-assembly of an aromatic small molecular anti-tumor active drug containing benzene rings, a polyphenol compound and indolecyanine derivatives or CY-series fluorescent dyes. The system isassembled on the basis of an electrostatic acting force and interaction among aromatic rings, has stable hydrophilicity in a neutral environment such as blood and is triggered by protons to be converted into large hydrophobic particles in an acidic environment of tumors in order to push the nano-drug to enter tumor cells and cause endosomal escape; when the neutral environment of the cytoplasm recovers, the system is converted into hydrophilic nano-particles again to release the drug. Meanwhile, the formed proton-triggered nano-drug system with the hydrophilic-hydrophobic-dimensional double conversion characteristics realizes application in the aspects of tumor bioimaging and chemotherapy, photo-thermal and photodynamic combined therapy and the like.

The invention discloses an efficient method for preparing tree moss absolute oil. The following devices are used: an ultrasonic extraction tank (1); a chromatography column (2); an air compressor (3);a concentration tank (4); a reverse resin column (5); a condenser (6); a vacuum pump (8); and a solvent recovery tank (7). The method comprises the following steps: 1) performing ultrasonic extraction of a tree moss raw material; 2) performing purification by the chromatography column (2); 3) performing concentration; 4) performing purification by the reverse resin column (5); and 5) removing ethanol under reduced pressure to obtain the tree moss absolute oil. The device of the invention can efficiently extract and purify the tree moss absolute oil, and the obtained tree moss absolute oil isused in the cigarettes, the electronic cigarettes or the heat-not-burn cigarettes, and can effectively improve the smoking comfort.

The invention belongs to the technical field of chemical drug synthesis and specifically relates to a preparation method of 2, 6-dichlorodiphenylamine. The preparation method of the 2, 6-dichlorodiphenylamine comprises the following steps: (1) adding 2, 6-dichlorodiphenylamine and a polar aprotic solvent into a reaction bottle; after the 6-dichlorodiphenylamine and the polar aprotic solvent are stirred and dissolved, adding chlorobenzene, alkali and a catalyst to an obtained mixture; stirring and heating the mixture to 120-160 degrees centigrade; and preserving the heat of the mixture for reaction for 2-4 h, wherein the catalyst is nanometer copper oxide or nanometer copper iodide; and (2) cooling a reaction mixture obtained in the step (1) to 50-90 degrees centigrade; filtering the cooledreaction mixture; carrying out reduced pressure distillation on a filter liquor to obtain a crude product; and purifying the crude product to obtain the 2, 6-dichlorodiphenylamine. The preparation method of the 2, 6-dichlorodiphenylamine, provided by the invention, has the advantages that the catalytic efficiency of the catalyst is high, the usage of the catalyst is less, the selectivity of a reaction solvent is good, the reaction solvent is easy to recover, the raw material cost is low, the yield of a prepared product is high, the purity is high, the quality is high, and the preparation method of the 2, 6-dichlorodiphenylamine is easy to realize industrial production and application.

The invention belongs to the technical field of chemical drug synthesis, and particularly relates to a preparation method of diclofenac. The preparation method comprises the following steps: (1) adding 2-chlorophenylacetic acid or 2-chlorophenylacetate and a polar aprotic solvent into a reaction bottle, performing dissolution under stirring, adding 2,6-dichloroaniline, an alkali, a catalyst and areaction accelerator, performing heating under stirring to 120-160 DEG C, and performing heat preservation for a reaction for 2-24 h, wherein the catalyst is nano copper oxide or nano cuprous iodide;and (2) cooling the reaction mixture obtained in the step (1) to 70-90 DEG C, performing filtration, performing reduced-pressure distillation on the filtrate to obtain a crude product, performing purification on the crude product, and performing drying to obtain the diclofenac. According to the method provided by the invention, the catalyst has high catalytic efficiency and a small usage amount, areaction solvent is easy to recover, the production costs are low, the prepared product has a high yield, high purity and high quality, and the industrial production application is easy to realize.

The invention relates to a continuous extraction method of pepper oleoresin, belonging to the technical field of extraction of natural pepper oleoresin. A method for continuous extraction of pepper oleoresin, comprising the following process steps: crushing pepper, extracting essential oil from crushed pepper; pretreating the pepper after extracting essential oil; turning the pretreated pepper The extraction device continuously extracts the extracting solution to obtain the pepper oleoresin extract, and the used extraction solution is a mixture of extraction solvent, dilution solvent and stabilizer; the obtained pepper oleoresin extract is continuously concentrated to remove the solvent to obtain the pepper oleoresin. The continuous extraction method of pepper oleoresin of the present invention can realize continuous extraction and continuous concentration and solvent removal of pepper oleoresin, has good extraction effect, high content of active ingredients, less amount of extraction solvent, high degree of automation, low production cost, and can realize large-scale industrial production.

The invention discloses a preparing method of fenugreek absolute oil. Following devices including an ultrasonic extraction tank (1), a chromatographic column (2), an air compressor (3), a concentration tank (4), a reverse resin column (5), a condenser (6), a vacuum pump (8) and a solvent recovery tank (7) are used. The method includes the steps of firstly, conducting ultrasonic extracting on fenugreek raw materials; secondly, conducting purifying through the chromatographic column (2); thirdly, conducting concentrating; fourthly, conducting purifying through the reverse resin column (5); fifthly, conducting decompressing to remove ethyl alcohol to obtain the fenugreek absolute oil. By means of the devices, the fenugreek absolute oil can be efficiently extracted and purified, the obtained fenugreek absolute oil is used for cigarettes, electronic cigarettes or heated-non-combusted cigarettes, and the sucking comfort is effectively improved.

The invention discloses a preparation method of fenugreek absolute oil, which uses the following devices: ultrasonic extraction tank (1); chromatography column (2); air compressor (3); concentration tank (4); reverse resin column ( 5); Condenser (6); Vacuum pump (8); Solvent recovery tank (7); The steps are: ① Ultrasonic extraction of fenugreek raw material; ② Purification by chromatography column (2); ③ Concentration; ④ Passing reverse resin Column (5) purification; ⑤ decompression except ethanol, promptly obtains described fenugreek absolute. The device of the present invention can efficiently extract and purify the fenugreek absolute oil, and the obtained fenugreek absolute oil can be used in cigarettes, electronic cigarettes or heat-not-burn cigarettes to effectively enhance and improve their smoking comfort.

The invention discloses a preparation method of rose absolute, which uses the following devices: an ultrasonic extraction tank (1); a chromatographic column (2); an air compressor (3); a concentration tank (4); ); Condenser (6); Vacuum pump (8); Solvent recovery tank (7); The steps are: 1. Rose raw material is ultrasonically extracted; 2. Purified by chromatography column (2); 3. Concentrated; 4. By reverse resin column (5) purify; 5. ethanol is removed under reduced pressure, promptly obtains described rose absolute. The device of the invention can efficiently extract and purify the rose absolute, and the obtained rose absolute can be used in cigarettes, electronic cigarettes or heat-not-burn cigarettes to effectively enhance and improve their smoking comfort.

The invention relates to a flame retardant phosphate tri(dimethyl siliconyl heterocyclic methylene) ester compound and a preparation method thereof. The structure of the compound is shown as a formulain the description. The preparation method comprises the following steps of dissolving dimethyl silicate trimethylol phosphine oxide cyclic ester into organic solvents at 20 DEG C under the nitrogengas protection; then, dripping phosphorus oxychloride; controlling the mol ratio of the phosphorus oxychloride to the dimethyl silicate trimethylol phosphine oxide cyclic ester to be 1:3-1:3.6; controlling the temperature not to exceed 60 DEG C in the dripping process; after the dripping completion, raising the temperature to 80 to 130 DEG C; performing heat insulation reaction for 8 to 10h for completely exhausting hydrogen chloride; performing purification treatment to obtain phosphate tri(dimethyl siliconyl heterocyclic methylene) ester. The compound has the advantages that double elementsof phosphorus and silicon are cooperated for flame retardance; the flame retardant efficiency is high; the compound is suitable for being used as the flame retardant for polyamide, polyester, polyurethane, epoxy resin, unsaturated resin, polyolefin and the like; the preparation method uses one-step reaction; the process is simple; the equipment investment is low; the industrialized production canbe easily realized.

The invention provides to a high temperature resistant forming agent and a preparation method thereof, which relate to the technical field of tertiary oil recovery of an oil field. The high temperature resistant forming agent is generated through the copolymerization of 6-acrylamicarboxylic acid, sodium methallyl sulfonate and 1-acryl oxide-2-pyrrolidone. The preparation method of the high temperature resistant forming agent includes the following steps: adding the sodium methallyl sulfonate and an initiator persulfate into a flask, performing magnetic stirring, and mixing the 6-acrylamicarboxylic acid and the 1-acryl oxide-2-pyrrolidone and adding a liquid dripping pump; after the temperature rises to 30 DEG C; injecting the 6-acrylamicarboxylic acid and 1-acryl oxide-2-pyrrolidone mixture into the flask, rising the temperature to 70 DEG C, after heat preservation, and adding a quinone polymerization inhibitor and then stopping the polymerization reaction, and after the reaction is stopped for 20-60 min, cooling to room temperature, and obtaining the high temperature resistant forming agent after separation and purification. According to the invention, the oil field recovery rateis improved under the environment of hot water, steam and high temperature flue gases.

The invention discloses a method for preparing coffee absolute. The following devices are used: an ultrasonic extraction tank (1); a chromatographic column (2); an air compressor (3); a concentration tank (4); ); Condenser (6); Vacuum pump (8); Solvent recovery tank (7); The steps are: 1. Ultrasonic extraction of coffee raw material; 2. Purification by chromatographic column (2); 3. Concentration; 5) purify; 5. decompression removes ethanol, promptly obtains described coffee absolute. The device of the present invention can efficiently extract and purify coffee absolute, and the obtained coffee absolute can be used in cigarettes, electronic cigarettes or heat-not-burn cigarettes to effectively enhance and improve their smoking comfort.