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Method for preparing dogwood alcohol extract particles and corresponding alcohol extract particles

A technology of dogwood alcohol and dogwood, which is applied in the field of solid beverages, can solve the problems of low content of ursolic acid and inability to achieve the effect of health care, and achieve the effect of improving stability and bioavailability

Inactive Publication Date: 2019-12-31
XIXIA COUNTY SENLINJIA FOOD CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the content of ursolic acid in the existing Cornus officinalis granules is very small, which cannot achieve a good health care effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A method for preparing corni alcohol extract granules, comprising the following steps:

[0025] (1) Water extraction: mix cornel dry fruit powder, citric acid, acetone, and deionized water in a weight ratio of 1:0.02:10:20, and extract at an ultrasonic temperature of 20°C and an ultrasonic power of 200W for 10 minutes. Ultrasound for 3 seconds with an interval of 2 seconds, after ultrasonic extraction, separate the residue from the liquid, keep the filter residue, and dry it for later use.

[0026] (2) Alcohol extraction: using water-alcohol solution as the extraction solution, mix the dried filter residue with the extraction solution containing a certain volume fraction of ethanol according to the ratio of 1g:25mL of solid to liquid, and perform ultrasonic extraction at 35°C for 30min. The ultrasonic power is 300w, every 3s of ultrasound with 3s interval; the frequency of ultrasonic extraction is 1 time, after ultrasonic extraction, the residue liquid is separated and ...

Embodiment 2

[0029] Example 2 Effects of Extracts Containing Different Volume Fractions of Ethanol on the Content of Ursolic Acid in Cornus officinalis Alcohol Extract Granules

[0030] With reference to the method for preparing corni alcohol extract particles described in Example 1, the diameter-to-height ratio of the fixed separation column is 1:8, the loading flow rate is 4BV / h, the pH value of the eluent is 7.5, and the flow rate of the eluent 7BV / h, change the volume fraction of ethanol in the extract, according to the specific value of the volume fraction of ethanol in the extract given in Table 1, prepare the ethanol extract particles of Cornus officinalis, and explore the effect of water-alcoholic solutions of different volume fractions on the alcohol extraction of Cornus officinalis. The influence of the content of ursolic acid in the pellets, the results are shown in Table 1.

[0031] Table 1 The content of ursolic acid in Cornus officinalis ethanol extract granules prepared from...

Embodiment 3

[0035] Example 3 Effect of Macroporous Resin Purification on Ursolic Acid Content in Cornus officinalis Ethanol Extract Granules

[0036] With reference to the method for preparing corni alcohol extract granules described in Example 1, the volume fraction of ethanol in the extract in the fixing step (2) is 80%, and the diameter-to-height ratio of the separation column in step (3) is 1:8. Sample flow velocity is 4BV / h, and the pH value of eluent is 7.5, and the flow velocity of eluent is 7BV / h, according to the step (1), (2), (3) and (4) of method described in embodiment 1 ) made corni alcohol extract granule as sample 1, according to the steps (1), (2) and (4) of the method described in Example 1, the corn cornel alcohol extract granule that makes is as comparative sample 1, i.e. contrast Sample 1 is not purified by macroporous resin adsorption in the preparation process; the content of ursolic acid in sample 1 and comparative sample 1 is detected, and the content of ursolic a...

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PUM

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Abstract

The invention belongs to the technical field of solid beverages, and particularly relates to a method for preparing dogwood alcohol extract particles. The method comprises the following steps: (1) dogwood dry fruit powder is uniformly mixed with 70-85% (v / v) of a water-alcohol solution according to the ratio of 1 g:(25-40) mL to obtain a suspension; (2) the suspension is ultrasonically extracted and then subjected to residue-liquid separation, and an alcohol extraction filtrate is retained; (3) the alcohol extraction filtrate is subjected to macroporous resin purification treatment; and (4) modified soyabean lecithin and alpha-cyclodextrin are added into the purified alcohol extraction filtrate, and through stirring, homogenizing and spray drying, the dogwood alcohol extract particles areobtained, wherein the using amount ratio of the modified soyabean lecithin to the alpha-cyclodextrin to filter residue or the dogwood dry fruit powder is (0.002 to 0.005):(0.05 to 0.09):1. The alcoholextraction filtrate is subjected to macroporous resin adsorption and purification, so that the content of ursolic acid in the dogwood alcohol extract particles is greatly increased.

Description

technical field [0001] The invention belongs to the technical field of solid beverages, and in particular relates to a method for preparing ethanol extract granules of Cornus officinalis, and also relates to the ethanol extract granules prepared by the method. Background technique [0002] Cornus officinalis is a unique traditional Chinese medicinal material in my country. The fruit of Cornus officinalis is rich in various beneficial components such as loganin, ursolic acid, morroniside, monosaccharides and polysaccharides. Among them, ursolic acid was once used as one of the quality control indicators of Cornus officinalis , it has been confirmed that ursolic acid can lower blood sugar, regulate blood lipids, scavenge free radicals in the body, protect pancreatic β cells, and alleviate the body's insulin resistance, so it has the potential for medical development. In the existing reported literature, animal experiments were carried out on ursolic acid. According to the rat e...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L2/39A23L2/70A23L2/52A23L33/105
CPCA23L2/39A23L2/70A23L2/52A23L33/105A23V2002/00A23V2200/328A23V2250/18A23V2250/5112A23V2300/10A23V2300/14A23V2300/48
Inventor 宋红昌张立攀李向力赵梦瑶李鹏冲尹红娜张亚勋杜瑞陈红王春杰王鋆坦李娜
Owner XIXIA COUNTY SENLINJIA FOOD CO LTD
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