356results about How to "Guaranteed clinical efficacy" patented technology

The invention provides a Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases which comprises the following raw material herbs (by weight portions): astragalus root 480-660, radix salvia miltiorrhiza 60-160, red peony root 60-160, rhizome of Sichuan lovage 60-160, Chinese angelica root 60-160, safflower 60-160, leech 40-90, ground beetle 40-90, peach kernel 60-160, artificial ox gallstone 10-40, antelope's horn 10-40, buthus martensi kirsch 50-140, polygala root 60-160, acorus gramineus soland 60-160 and medicinal adjuvant. The invention also provides the method for preparation and use of the composition.

The invention relates to a medicinal preparation for treating nerve-root cervical spondylopathy, and a preparation method and a quality detection method thereof. The invention is an extension of an original invention. The medicinal preparation comprises a granule, a tablet and a capsule, the preparation method is an optimized and screened production technology based on the original invention, a modern new device, a new process and a new technique are adopted to realize industrial production; and quality standard researches are completed and improved on the basis of original standards, HPLC is adopted to simultaneously determine the content of ginsenoside Rg1, ginsenoside Rb1 and notoginsenoside R1 in a finished product, and thin layer discrimination of all medicines is carried out to comprehensively control the quality, so the clinic curative effects are guaranteed.

The invention discloses a preparation method and a detection method of febuxostat raw material. The preparation method comprises Cyanophenol, DMF (Dimethyl Formamide) saturated with HCl, and thioacetamide are mixed and react to obtain an intermediateIII; the intermediate III, anhydrous ethyl alcohol, 2-chlorination acetoacetic ester are mixed and react to obtain an intermediate IV; the intermediate IV, hexamethylene tetramine and polyphosphoric acid are mixed and react to obtain an intermediate V; the intermediate V, DMF, anhydrous potassium carbonate and bromo-2-methylpropane are mixed and react to obtain an intermediate VI; the intermediate VI, anhydrous formic acid, oxammonium hydrochloride and sodium formate are mixed and react to obtain an intermediate VII; the intermediate VII, anhydrous ethyl alcohol and sodium hydroxide are mixed and react to obtain a febuxostat crude product; and refining and crystal transformation are performed to the febuxostat crude product to obtain the febuxostat raw material. Aiming at avoiding defects in the prior art, the preparation technology of the febuxostat raw material is optimized, and a systematic, complete and effective component identifying and content measuring method is established.

The invention discloses a method for controlling the quality of a traditional Chinese medicine preparation-Runzao Zhiyang tablet. The quality control method includes the steps of adopting the thin-layer chromatography to identify kuh-seng and mulberry leaves and adopting the high performance liquid chromatography to determine the content of matrine in the preparation. The quality control method is reliable and feasible, and can guarantee the product quality and the clinical efficacy.

The invention provides a quality detection method of a traditional Chinese medicinal composition for curing diabetic retinopathy. Raw medicines of the traditional Chinese medicinal composition comprise, by weight, 30-60 parts of Radix Astragali, 9-15 parts of ligustrum lucidum, 9-30 parts of motherwort, 3-10 parts of dark plum, 2-9 parts of coptis, 1-5 parts of cortex cinnamomi and 3-9 parts of Buddleja officinalis. The quality detection method comprises steps as follows: content determination of astragaloside, berberine and linarin in the traditional Chinese medicinal composition and thin-layer chromatography of the above seven raw medicines. The quality detection method provided by the invention has advantages of high specificity, simple, accurate and reliable operation and good reappearance. By the quality detection method, clinical medication safety can better be guaranteed.

The invention provides a Chinese medicinal composition for treating heart failure. The composition includes the following herbal medicines in parts by weight: 65-185 parts of codonopsis pilosula, 65-185 parts of acanthopanax root, 65-185 parts of astragalus root, 65-185 parts of root of red-rooted salvia, 15-185 parts of turtle shell, 50-150 parts of tuckahoe, 30-130 parts of semen lepidii, 50-150 parts of dwarf lilyturf root, 30-130 parts of bitter orange and medicinal auxiliary materials. Meanwhile, the invention provides a preparation method of the Chinese medicinal composition for treating heart failure. The Chinese medicinal composition is used for treating the heart failure. The Chinese medicinal composition has the effects of overcoming the defects of the conventional formulations of medicinal broth and the like; by using a water extraction method, active ingredients with a clinical curative effect in the composition are remained; by using high-efficiency dynamic loop extraction equipment, the active ingredients are extracted to the greatest extent; and thus, the clinical curative effect of the composition is guaranteed, and the prevention and treatment effect of the composition on qi deficiency, blood stasis and water retention symptoms of the heart failure is obviously superior to those of similar medicaments.

The invention discloses a detection method for traditional Chinese medicine preparation compounded Sichuan fritillary bulb extract tablets. The detection method comprises the steps of carrying out thin-layer chromatography qualitative identification and carrying out content determination, wherein thin-layer chromatography qualitative identification comprises the steps of identifying ephedrannin and neoephedrine A in the preparation, identifying polygala root and cynanchum atratum and identifying glycyrrhiza uralensis and schisandra fruit; content determination comprises the step of determining the content of ephedrine hydrochloride in the preparation. The detection method disclosed by the invention has the advantages that the mixing of radix ephedrae and cynanchum atratum is effectively controlled, and meanwhile, the composition and content of the compounded Sichuan fritillary bulb extract tablets is effectively controlled, so that the drug can be safer and more effective.

The invention discloses a traditional Chinese medicine composition with the effects of clearing the lung, moistening dryness and relieving sore throat. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5-15 parts of platycodon root, 3-10 parts of dwarf lilyturf tuber, 5-20 parts of dried tangerine peel, 5-15 parts of coastal glehnia root, 2-12 parts of gynostemma pentaphyllum, 1-8 parts of blackberrylily rhizome, 8-12 parts of ginkgo seeds, 150-300 parts of yellow-peel pears, 5-15 parts of Indian trum etflower seed, 5-15 parts of ginkgo leaf, 2-10 parts of liquorice root, 5-15 parts of mulberry leaves, 2-12 parts of honeysuckle flower, 5-15 parts of loquat leaf, 2-12 parts of corn stigma, 5-15 parts of peppermint, 1-12 parts of lotus leaf, 1-3 parts of green tea, 3-15 parts of fruit-spike of common selfheal, 0.5-6 parts of Chinese magnoliavine fruit and 3-15 parts of sea buckthorn fruit. According to the traditional Chinese medicine composition disclosed by the invention, herbal medicine formulas and dosage compatibilities can be preferably obtained by adopting treatment based on syndrome differentiation according to the theories of traditional Chinese medicines, and clinical experiment results show that the traditional Chinese medicine composition has very good effects of clearing and benefiting the throat and palate, moistening the lung, and reducing phlegm and stopping coughing, and has very good treatment effects on respiratory tract diseases such as chronic pharyngitis, pneumonia and cough.

The invention discloses a standard for determining the content of medicinal montmorillonite, and in particular relates to a standard for controlling the content of silicon dioxide and aluminium sesquioxide in a quality standard of medicinal montmorillonite with pertinence. The standard is characterized in that the content standard of silicon dioxide and aluminium sesquioxide is as follows: the content of montmorillonite needs to be between 95.0 and 105.0 percent; according to the calculation of dry matter, the content of silicon dioxide (SiO2) needs to be between 55 and 65 percent; and the content of aluminium sesquioxide (Al2O3) needs to be between 12 and 22 percent.

The invention discloses an antibacterial anti-inflammatory capsule quality detection method. Antibacterial anti-inflammatory capsules are prepared from honeysuckle flowers, radix stemonae, Chinese rhubarb, folium isatidis, radix scutellariae, rhizoma anemarrhenae and a christina loosestrife herb. The antibacterial anti-inflammatory capsule quality detection method comprises the four steps of suitability test on chromatographic conditions and a system, preparation of a reference substance solution, preparation of a test sample solution and determination. In addition, the radix stemonae, the Chinese rhubarb, the radix scutellariae, the rhizoma anemarrhenae and the honeysuckle flowers are subjected to thin-layer identification. The antibacterial anti-inflammatory capsule quality detection method has the advantages of being simple and easy to operate and capable of effectively controlling the product quality.