191 results about "Callicarpa nudiflora" patented technology

The invention relates to a nakedflower beautyberry extract as well as a preparation method, a preparation and an application thereof. The nakedflower beautyberry extract is an extract which is extracted from nakedflower beautyberry leaves and contains a nakedflower beautyberry total flavonoid compound and a tannide class compound. The extract is obtained by the steps of extracting the nakedflower beautyberry leaves by water, diluted alcohol or diluted ketone and carrying out macroporous adsorptive resin column chromatography purification on an extracting solution after being concentrated. The nakedflower beautyberry extract has high purity and has the functions of bacteriostasis, hemostasis, pain relieving and convergence.

The invention provides a callicarpa nudiflora extract, and a preparation method and application preparation method, particularly a callicarpa nudiflora extract and a preparation method thereof, and application of the extract in preparing medicines for inhibiting bacteria, arresting bleeding and relieving pain as well as in oral cleaning products.

Relating to the field of traditional Chinese medicine preparation, the invention provides a Callicarpa nudiflora Hook. et Arn. extract, and its preparation method and application. Containing flavonoid and water-soluble ingredients, the Callicarpa nudiflora Hook. et Arn. extract is characterized by additionally containing diterpene and triterpene fat-soluble ingredients. The Callicarpa nudiflora Hook. et Arn. extract of the invention is extracted by supersonic waves for preparing bacteriostatic, antiphlogistic, hemostatic and astringent medicaments. The beneficial effect of the extract provided in the invention is that: not only containing flavonoid, tannin and other water-soluble ingredients, but also containing diterpene and triterpene fat-soluble ingredients, the extract of the invention has more complete active ingredients and a comparatively increased content, thus being beneficial to the application of various preparations. Requiring no heating, the preparation method of the invention is energy saving and of high extraction rate.

The invention provides a method for improving sprouting rate and seedling rate of callicarpa nudiflora. The method comprises: a material preparation stage, a seed treatment stage and a subsequent management stage. After treatment with the method provided by the invention, the sprouting rate of the callicarpa nudiflora is more than 75%, the seedling rate of the callicarpa nudiflora is more than 70%, and initial sprouting time is from 9 days to14 days. Compared with the prior art, the method has the advantages that the sprouting time is obviously shortened, the sprout uniformity is good, and the sprouting rate and the seedling rate are high; and the treatment method is simple and suitable for intensification non-polluted cultivation and farmer scattered cultivation and has strong applicability and popularization property, thereby solving the problems that the existing callicarpa nudiflora is low in the sprouting rate and seedling rate and is not uniform in sprouts.

The invention discloses a callicarpa nudiflora extract with an anti-inflammatory effect. The callicarpa nudiflora extract contains 24%-36% of flavonoid compound, 0.8%-3% of phenethyl alcohol glycoside and 15%-27% of diterpenoid compound. The obtained callicarpa nudiflora extract has high anti-inflammatory activity.

The invention provides application of callicarpa nudiflora extract in daily chemical cleaning products. In the application, the callicarpa nudiflora extract is added into hand sanitizer, soap, foot cleaning fluid, bath foam and cleanser series daily chemical cleaning products. The prepared callicarpa nudiflora series daily chemical cleaning products are safe, and have unique effect.

The invention discloses a callicarpa nudiflora effective part extract with a hemostatic effect and a preparation method of a pharmaceutical preparation of the callicarpa nudiflora effective part extract. The effective part extract and the pharmaceutical preparation contain total flavonoids of the callicarpa nudiflora and are extracted and separated from the callicarpa nudiflora which is a traditional Chinese medicine plant, the content of the total flavonoids is not less than 50%, and the effective part extract and the pharmaceutical preparation mainly contain galuteolin, luteolin-3'-O-beta-D-glucopyranoside, luteolin-4'-O-beta-D-glucopyranoside, calliterpenone, luteolin, apigenin and cosmosiin. The effective part extract and the pharmaceutical preparation have significant hemostatic effects.

The invention discloses a callicarpa nudiflora medicine, an intermediate and a fingerprint detection method of a preparation. The method comprises the following steps: (a) preparation of a reference solution; (b) preparation of a test solution; (c) chromatographic condition; (d) formulation of a standard fingerprint of isoacteoside as a reference peak; and (e) quality control of the fingerprint. According to the above method, a pretreatment method of each tested object is simple, characteristic constituents are retained completely, stability is good, precision is high, and there is certain specificity. The separation effect of each characteristic peak in the fingerprint is good. The callicarpa nudiflora medicine, the intermediate and the fingerprint of the preparation have good correlation. The method can be used for identifying quality of the callicarpa nudiflora medicine and increasing production process controllability of the callicarpa nudiflora preparation, and is helpful for guaranteeing quality stability and clinical efficacy of the callicarpa nudiflora preparation. The invention also discloses the callicarpa nudiflora medicine obtained according to the above fingerprint detection method, the intermediate and the standard fingerprint of the preparation.

The invention discloses premixed feed for sows in perinatal periods and a method for preparing the premixed feed. Every 1 kg of the premixed feed comprises Chinese herbal medicine components including 1-10 g of rhizoma atractylodis macrocephalae, 1-10 g of radix glycyrrhizae, 1-10 g of semen cuscutae, 1-10 g of rhizoma polygonati odorati, 1-10 g of rhizoma chuanxiong, 1-10 g of radix astragali and 1-10 g of callicarpa nudiflora. The premixed feed and the method have the advantages that the special premixed feed which is applicable to the perinatal periods of the sows is developed for physiological statues and nutrient requirements of the sows in the perinatal periods; the unique physiological statues of the sows in the perinatal periods are sufficiently considered, and the premixed feed is in a comprehensive nutrient supply and healthful diet formula; the premixed feed is favorable for smooth delivery of the sows, multiple live piglets can be farrowed by the sows, and healthy development of the piglets can be promoted.

Disclosed is a gynecopathy external use washing lotion and a preparation method thereof. The invention relates to a pharmaceutical composition and a preparation method thereof. The washing lotion contains the following components: Callicarpa nudiflora, senecio, radix sophorae falvescentis, stemona, broom cypress fruit, common cnidium fruit, borneol, chlorhexidine acetate and essence. The preparation method comprises the steps of extraction of the above-mentioned components, alcohol precipitation and preparation. The beneficial effects of the invention are as follows: the washing lotion prepared in the invention has no side effects to human bodies and shows good effects on sterilization and detoxification; a small quantity of safe and effective western medicinal components are used as accessories to the washing lotion, which endows the washing location with characteristics of safety, rapidness and efficiency. The preparation method provided in the invention abandons the conventional process of hot reflux extraction of traditional Chinese medicinal materials and has the advantages of a short preparation time, low energy consumption and high extraction efficiency, and is favorable for protecting environment and saving cost.

The invention discloses a method for planting callicarpa nudiflora seedlings. The method includes: (1) starting to breed seeds in every March to April; (2) ridging a plurality of ridges in a field before seed breeding, applying organic fertilizer decayed from pig manure after ridging; (3) immersing the seeds; (4) uniformly sowing the immersed seeds on the ridges; (5) covering the ridges with thesown seeds with sunshade nets, watering the ridges every day to keep the humidity of the ridges within 75% to 85%; (6) transplanting the callicarpa nudiflora seedlings into nutrient bags when the seedlings are 1.5-2cm in height; and (7) watering once every day, transplanting the seedlings into a large field when the seedlings grow to 0.2 to 0.3m in height after 30-40 days; and managing the field. The method for planting the callicarpa nudiflora seedlings is simple in process, budding rate of the seeds is higher than 95%, survival rate of the seedlings transplanted and managed in the large land is higher than 90%, budding costs about 4 days, and budding time is obviously shortened. Besides, the method for planting the callicarpa nudiflora seedlings is simple, has strong applicability and generalization performance, and can solve the problem that existing callicarpa nudiflora is low in budding rate and seedling percentage and ragged in budding.

The invention provides a traditional Chinese medicine health-care absorbing article which comprises a liquid penetrable surface layer (1), a liquid unpenetrable surface layer (5), an absorption core (4) between the former two layers, wherein the absorption core comprises a medicine filling layer (2) close to the liquid penetrable surface layer and an absorbing layer (3) formed by wood pulp and / or fluff slurry and / or ultra-absorption polymer, and further comprises a fixing gum (6) and a piece of gum protecting stripping paper (7); the traditional Chinese medicine in the medicine filling layer (2) takes callicarpa nudiflora as main raw material, and also comprises radix sophorae flavescentis and blumea balsamifera. The absorbing article provided has the functions of resisting and arresting bacterium, ridding dampness, alleviating pain, and killing parasites to relieve itching.

The invention belongs to the technical field of vegetative propagation of plants and particularly relates to a rapid propagation method of callicarpa nudiflora. The method comprises the following steps of 1 preparing ear seedlings; 2 preparing a mixed matrix; 3 preparing and cutting cuttings; 4 performing later period management and maintenance. By means of the rapid propagation method, the time required for rooting can be effectively shortened, the rooting percentage is obviously improved, the root number and the maximum root length are obviously increased, and the root slanting rate is reduced. The seedling emergency percentage of produced nursery stocks and survival rate of transplanted nursery stocks are high. Good characters of stock plants can be kept stable and reliable by means of the rapid propagation method. The rapid propagation method is low in cost and easy to popularize technologically and has wide application prospect.

The invention relates to poultry feed containing callicarpa nudiflora and a preparing method of the poultry feed. The poultry feed is prepared from the following ingredients, by weight: 40 to 60 parts of fish meal, 10 to 30 parts of bone meal, 1 to 5 parts of sodium chloride, 5 to 10 parts of gypsum, 1 to 2 parts of sodium glutamate and 10 to 30 parts of callicarpa nudiflora. According to the invention, the poultry feed is prepared from callicarpa nudiflora, fish meal, bone meal and auxiliary materials which are mixed according to a specific proportion, and has the effects of preventing and curing bird flu. With the poultry feed, the immune system functions of poultry can be enhanced, and the poultry can be protected from infection of epidemic diseases.

The invention relates to a method for rapid release of Callicarpa nudiflora seed dormancy. The method comprises the following steps: 1) impregnating Callicarpa nudiflora seeds for 12-24h with one or more selected from 5-20 wt% of a plant ash water solution, 100-300mg / L agibberellin (GA3) aqueous solution and 100-300mg / L alpha-naphthaleneacetic acid (NAA), and then washing the seedswith water; and step 2) germinating the impregnated seeds in the step 1). The method for rapid release of Callicarpa nudiflora seed dormancy provided by the invention can effectively relieve various factors hindering germination of the Callicarpa nudiflora seeds, including mechanical barrier formed by the seed coat, break Callicarpa nudiflora seed dormancy, and enhance seed germination rate to 95%. Compared with a traditional seedling raising way without treatment, the method has advantages of shortened breeding cycle, uniform seedlings, and simple operation and low cost, and can be widely used for breeding and cultivation of a Callicarpa nudiflora medicinal material.

The invention provides a composition for prompting wound healing. The composition mainly comprises the following components in parts by mass: 10 to 15 parts of fish collagen powder, 10 to 15 parts of carboxymethyl chitosan, 5 to 10 parts of pearl powder and 1 to 5 parts of callicarpa nudiflora extractive. The invention also provides a method for preparing the composition for prompting wound healing. The composition for prompting wound healing can be used as a dressing to be directly applied to a wound to form a protection film on the wound surface, so as to take the effects of diminishing inflammation, inhibiting bacteria and reducing scar, or can also be used as an additive to be prepared into preparations of other forms like emplastrum, ointment and spray.

The invention discloses a quality detection method of a traditional Chinese medicine callicarpa nudiflora preparation, belonging to the technical field of medicine quality control. The quality detection method comprises the following steps of: (1) preparation of a comparison product solution, (2) preparation of a test product solution, (3) chromatographic condition, (4) making of a standard fingerprint spectrum which takes galuteolin as a reference peak, and (5) quality control of the fingerprint spectrum. Compared with the prior art, in the quality detection method disclosed by the invention, a high-performance liquid chromatography is adopted to establish the standard fingerprint spectrum; based on the active ingredient characteristics of callicarpa nudiflora, quantization parameters are obtained through the fingerprint spectrum; and the method is favorable in repeatability and stability and high in degree of precision, can more comprehensively control and reflect the quality of the preparation and can ensure the uniform stability, the safety and the effectiveness of the product quality.

The invention discloses a tissue culture rapid propagation method of callicarpa nudiflora. The method performs control on the explant collection, disinfection method, differentiation, multiplication, screening of a rooting medium, selection of a transplanting matrix, environmental conditions in the culture process and the like. By adopting the methods of explant selection, inoculated culture, propagation expanding culture, rooting culture and hardening-seedling transplanting, a set of complete callicarpa nudiflora tissue culture rapid propagation technology system is established, so that the differentiation rate reaches 100%, the monthly multiplication coefficient reaches 4.95, the rooting rate reaches 93.7%, and the transplanting survival rate exceeds 90%. The method disclosed by the invention is simple and easy to implement, simple in process and high in efficiency, effectively suppresses the pollution and browning of the callicarpa nudiflora explant, improves the differentiation rate of the tissue culture seedling, realizes fast multiplication, high rooting rate, high survival rate and low cost, and provides a reliable technical means for large-scale production of callicarpa nudiflora seedlings.

The invention relates to the application of a pharmaceutical composition in the preparation of a drug for treating postoperative adhesions. The pharmaceutical composition uses the extract of Auranthus nudiflora as an active ingredient. The purple bead extract of the naked flower of the invention has a good effect on postoperative adhesion, and has the characteristics of low price, good safety and the like.

The invention discloses a plant extract compound capable of inhibiting bacteria, resisting inflammation, stopping bleeding and relieving pain and an application of the plant extract compound. The plant extract compound is prepared from callicarpa nudiflora extract and flavonoids according to a mass ratio of (1-5) to (5-1). The callicarpa nudiflora extract has the functions of resisting inflammation, inhibiting bacteria, resisting viruses, stopping blood, relieving pain, adjusting immunity, removing free radicals and resisting oxidation; the callicarpa nudiflora extract has an effect of resisting most of pathogenic bacteria to different extents. The flavonoids have the effects of inhibiting dental caries, effectively degrading bacterial endotoxin, and preventing and treating periodontitis. The antibacterial, anti-inflammatory, analgesia and hemostasis experiments prove that the plant extract compound is exact in therapeutic effect, natural, healthy and easy to produce; the use effect of the plant extract compound is obviously superior to that of the components of oral cavity cleaning products. Therefore, the plant extract compound has a good market development prospect.

The invention belongs to the technical field of medicines and particularly relates to a callicarpa nudiflora extract or a diterpene compound separated from an overground part of callicarpa nudiflora and medical application of pharmaceutical composition prepared from the callicarpa nudiflora extract and the diterpene compound to preparation of medicines for treating gliomas. According to in-vitro tests, the callicarpa nudiflora extract and the diterpene compound can play a role in inhibition of human brain malignant spongioblastoma U251 cells by inhibition of cell proliferation and induction of cell apoptosis and can be used for development of the medicines for treating the gliomas.

The invention relates to the field of natural drug and specifically relates to a callicarpa nudiflora extract containing phenylethanoid glycoside and a preparation method thereof. The preparation method comprises the following steps of: heating callicarpa nudiflora leaves with water, carrying out reflux extraction, filtering the extracting solution, concentrating, adding a clarifying agent for clarifying the concentrated solution, enabling the clarified solution to pass through a macroporous resin column, firstly eluting with pure water, then, eluting with alcohol with low-concentration alcohol, finally, eluting with high-concentration alcohol, collecting the high-concentration alcohol eluant and drying, thus obtaining the callicarpa nudiflora extract. In the callicarpa nudiflora extract provided by the invention, total phenylethanoid glycoside content is up to 60-80%, and the sum of contents of three constituents including forsythiaside B, verbascoside and isoacteoside is up to 50%-70%.

The invention relates to a nudiflower beautyberry leaf capsule or granule and preparation method thereof, which consists of boiling nudiflower beautyberry leaf with water, filtering boiled liquid, concentrating, spray drying, charging medically acceptable excipient, palletizing to obtain hard gelatin capsule or pelletized granule.

The invention relates to a composition of a callicarpa nudiflora extract, and particularly provides a composition of a callicarpa nudiflora extract with a pharyngitis treatment function. The composition is prepared from the following components in parts by weight: 45 to 58 parts of total flavonoids of callicarpa nudiflora, 35 to 52 parts of total phenylglycosides of callicarpa nudiflora, and 28 to40 parts of total phenolic acids of callicarpa nudiflora. The invention also discloses application of the composition. The composition has the advantages that the three components are respectively extracted from the callicarpa nudiflora, the components are accurate, and the synergistic function is realized; the good pharyngitis treatment and / or preventing effect is realized.

A vaginal effervescent tablet with high release speed and no irritation is prepared from achamydeous beautyberry leaf, effervescent agent and auxiliary. Its preparing process is also disclosed.

The invention discloses a method for cultivating callicarpa nudiflora and belongs to the field of agricultural biotechnology. The method includes selecting one-year-old half-lignified callicarpa nudiflora branches for cuttage in July to August; flatly cutting scion wood to be cutting of 8-10cm; using a BRs solution of 0.1-0.3mg / L in concentration to soak the cutting for 12-24h before cuttage; maintaining cuttage density to be 5cmx10cm; hardening seedlings after two mouths of cuttage; cultivating the seedlings to March of the next year for transplanting. In the method, the BRs solution of 0.1-0.3mg / L in concentration is utilized to soak fresh tender branches of callicarpa nudiflora for cuttage to cultivate clonal seedlings of callicarpa nudiflora, so that rooting rate and survival rate of cutting seedlings of callicarpa nudiflora can be increased, large-scale quick cultivation is realized, the seedlings are high in growing speed and can grow to about 1.2m in the year of transplanting, and the method is low in seedling growing cost and high in labor efficiency, reaches 85.3% in cuttage rooting rate, reaches 91.52% in transplanting survival rate and can meet production and market needs well.

The invention provides a callicarpa nudiflora dispersible tablet and a preparation method thereof. The preparation method comprises the following steps of: grinding callicarpa nudiflora into coarse powder, adding the coarse powder in an ethanol solution for soaking for 3-5 hours to obtain a primary extraction liquid, ultrasonically extracting the primary extraction liquid for 10-15 minutes under the power of 300-500w to obtain an extraction liquid, wherein the volume ratio of the coarse powder to the ethanol solution is 1:(3-7); concentrating and drying the extraction liquid to obtain dry paste powder; adding 20-30wt% of filling agent, 2-5wt% of disintegrating agent and 3-10wt% of adhesive to 60-70% of the dry paste powder, uniformly mixing and grinding into fine powder; pelletizing the fine powder to obtain a soft material; and tabletting the soft material to obtain the callicarpa nudiflora dispersible tablet. The callicarpa nudiflora dispersible tablet provided by the invention can be used for solving the problems of low content of active ingredients and poor bioavailability of the existing callicarpa nudiflora dispersible tablet.

The invention discloses an exogenous injury nursing spray prepared by virtue of the compatibility of the following raw materials in parts by weight: 5-15 parts of radix notoginseng, 6-15 parts of safflower, 3-9 parts of myrrh, 7-15 parts of dragon's blood, 2-6 parts of Chinese angelica, 5-20 parts of common jasminorange, 4-12 parts of woodland beakchervil root powder, 4-10 parts of borneol, 3-9 parts of mint, 4-16 parts of corydalis tuber, 6-10 parts of holly, 4-12 parts of callicarpa nudiflora, 6-12 parts of Japanese thistle herbor roots, 7-15 parts of potmarigold calendula, 2-4 parts of salicylic acid methyl ester, 2-5 parts of ginger camphor oil and 2-6 parts of cinnamon oil. The medicament disclosed by the invention is prepared from natural pure traditional Chinese medicines, the potency of drug can directly reach a deep part of an affected part by adopting a spraying manner, and the medicament has a very good curative effect on exogenous injuries including burns, scalds, postoperative wound inflammation, traumatic ulcers, worms and the like, and does not have any toxic or side effect.

The invention discloses a method for simultaneously determining three kinds of phenylethanoid glycoside compositions in a callicarpa nudiflora preparation through HPLC. The method comprises: (1) preparation of a contrast sample solution; (2) preparation of a to-be tested sample solution; and (3) HPLC detection. The method is simple in operation, high in accuracy, good in specificity, relatively high in precision and good in reappearance, and is beneficial for guaranteeing stable quality of the callicarpa nudiflora preparation and clinic curative effect.