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Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, preparation method and application thereof

A cerebrovascular disease and composition technology, which is applied in the field of traditional Chinese medicine compositions for the treatment of cerebrovascular diseases, can solve the problems of loss of fat-soluble components, volatile components, influence on the clinical efficacy of compound prescriptions, etc., so as to reduce the disability rate and improve the quality of health. , improve the effect of treatment

Active Publication Date: 2007-05-23
天津市石天药业有限责任公司
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AI Technical Summary

Problems solved by technology

In terms of clinical medication methods, decoction is mostly used in clinical practice, resulting in a serious loss of fat-soluble components and volatile components of the medicinal flavor, which affects the clinical efficacy of the compound.

Method used

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Examples

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Effect test

preparation example Construction

[0040] The dynamic cycle multifunctional extraction and concentration equipment adopted in the preparation method of the Chinese medicine composition of the present invention has the following specific steps:

[0041] a) Pulverization: pulverize the antelope horns into fine powder (80-120 mesh); leech, scorpion, and ground beetle are dried (80-120° C.), and pulverized into fine powder (80-120 mesh) with a micro pulverizer;

[0042] b) Extraction of volatile oil: Chuanxiong, Angelica, and Shichangpu are placed in an extraction tank to extract volatile oil by distillation. After boiling, the vapor pressure is ≤0.04Mpa, and the extraction time is 3 to 8 hours (5 hours is the best).

[0043] Supercritical CO can also be used 2 Extraction method to extract volatile oil

[0044] The obtained volatile oil is put in the cold storage for standby, the water liquid is collected in another device, and the medicinal residue is for standby.

[0045] c) Ethanol extraction: put Salvia milti...

Embodiment 1

[0061] Astragalus 480, Salvia 60, Radix Paeoniae Rubra 60, Rhizoma Chuanxiong 160, Angelica 160, Safflower 60, Leech 40, Wood Beetle 90, Peach Kernel 60, Artificial Bezoar 15, Antelope Horn 40, Scorpion 60, Polygala 160, Shichangpu 60.

[0062] According to the above prescription proportions, the capsules are prepared according to the preparation method of the above-mentioned traditional Chinese medicine composition.

Embodiment 2

[0064] Astragalus 660, Salvia 160, Radix Paeoniae Rubra 160, Ligusticum Chuanxiong 60, Angelica 60, Safflower 160, Leech 90, Wood Beetle 40, Peach Kernel 160, Artificial Bezoar 40, Antelope Horn 15, Scorpio 140, Polygala 60, Shichangpu 160.

[0065] According to the above prescription proportions, the capsules are prepared according to the preparation method of the above-mentioned traditional Chinese medicine composition.

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Abstract

The invention provides a Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases which comprises the following raw material herbs (by weight portions): astragalus root 480-660, radix salvia miltiorrhiza 60-160, red peony root 60-160, rhizome of Sichuan lovage 60-160, Chinese angelica root 60-160, safflower 60-160, leech 40-90, ground beetle 40-90, peach kernel 60-160, artificial ox gallstone 10-40, antelope's horn 10-40, buthus martensi kirsch 50-140, polygala root 60-160, acorus gramineus soland 60-160 and medicinal adjuvant. The invention also provides the method for preparation and use of the composition.

Description

technical field [0001] The invention belongs to traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition for treating cerebrovascular disease of Qi deficiency and blood stasis type, wind-phlegm blockage collateral type, and Yin-deficiency wind movement type ischemia and its composition. Preparation method and application. Background technique [0002] Cerebrovascular disease is one of the three major diseases leading to human death. It is a common nervous system disorder. According to traditional Chinese medicine, it is stroke. Among them, the incidence rate reaches 80% because of ischemic cerebrovascular disease, which can cause severe disability. According to the data released by the World Neurology Congress in 1997, the global stroke incidence, mortality and disability rates are still high, and the incidence rate shows obvious regional differences. 47-198 / 100,000 women, the incidence rate increases significantly with age. Di...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/884A61K9/00A61K9/06A61K9/14A61K9/16A61K9/20A61K9/48A61P9/10A61K35/64A61K35/62A61K35/413A61K35/32A61K35/646
Inventor 石学敏李进李正马广信胡国强刘雪平阎雪梅崔维利吕明远李连萍李庆书王骞
Owner 天津市石天药业有限责任公司
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