34results about How to "% efficacy" patented technology

A method for treating a glycolipid storage-related disorder, comprising administering a therapeutically effective amount of an inhibitor of glycolipid synthesis in combination with an agent capable of increasing the rate of glycolipid degradation or in combination with bone marrow transplantation. Inhibitors of glycolipid synthesis include N-butyldeoxynojirimycin (NB-DNJ), N-butyldeoxygalactonojirimycin (NB-DGJ) or N-nonyldeoxynojirimycin (NN-DNJ). Glycolipid storage-related disorders include Gaucher disease, Sandhoff's disease, Fabry's disease, Tay-Sach's disease, Niemann-Pick C storage disease, GM1 gangliosidosis, genetic disorders in which neuronal glycolipid accumulation contributes to disease pathology.

Polypeptides are provided that are capable of significantly inhibiting and / or neutralizing P aeruginosa. The polypeptides comprise two or more immunoglobulin single variable domains that are directed against the PcrV protein of P. aeruginosa, wherein the “first” immunoglobulin single variable domain and the “second” immunoglobulin single variable domain have different paratopes.

Polypeptides are provided that are capable of significantly inhibiting and / or neutralizing P. aeruginosa. The polypeptides comprise two or more immunoglobulin single variable domains that are directed against the PcrV protein of P. aeruginosa, wherein the “first” immunoglobulin single variable domain and the “second” immunoglobulin single variable domain have different paratopes.

Methods of controlling agricultural pests are disclosed. An aerated liquid mixture is formed from a composition containing a bacterial nutrient source, a nitrogen-containing compound, a phosphate-containing compound, a magnesium-containing compound, a buffer, a chitinase inducer, and at least one strain of bacteria that produces chitinase. The liquid mixture is administered to soil and plants, and acts as an organic biological pesticide.

A current breaker comprises a multi-layer printed circuit board (PCB), a ground plane, a metal component and a conductive via hole. The ground plane is disposed in a first metal layer of the multi-layer PCB and comprises a slot forming inductive impedance. The slot comprises an extended portion. The metal component is disposed in a second metal layer of the multi-layer PCB. Capacitive impedance is formed between the metal component and the ground plane. The projection of the metal component on the ground plane and the extended portion of the slot partially overlap. The conductive via hole penetrates the multi-layer PCB to connect metal component with the ground plane. The first and the second metal layers are any two metal layers of the multi-layer PCB. The inductive impedance formed by the slot and the capacitive impedance formed between the metal component and the ground plane create a parallel LC equivalent circuit.

The invention discloses a traditional Chinese medicine composition capable of relieving non-alcoholic steatohepatitis, a preparation method and a product thereof. The traditional Chinese medicine composition contains capillary root, hedyotis diffusa, gardenia root and mulberry root in a proportion of 1:0.8-1.5:0.2-1.2:0.2-1.2, after extracting the above components with water and then concentrating, the above-mentioned traditional Chinese medicine composition can be obtained. The traditional Chinese medicine composition can be made into health products or medicines, and has important effects on alleviating non-alcoholic steatohepatitis. Experiments have proved that the traditional Chinese medicine composition of the invention can effectively reduce liver swelling, improve liver pathological changes, reduce liver lipid accumulation, reduce liver inflammatory factor levels, and effectively relieve NASH.

Presented herein, in certain embodiments, are compositions comprising antibody binding agents that specifically bind to A. baumannii and inhibit and / or block A. baumannii infection, and uses thereof.

The invention discloses a compound gingko health product solid preparation which is prepared by mixing ginkgo leaf extract, salvia miltiorrhiza bunge, American ginseng, seabuckthorn flavone and gelatin or an enteric substrate. The compound gingko health product solid preparation comprises the following effective components in parts by weight: 1-60 parts of ginkgo leaf extract, 1-60 parts of salvia miltiorrhiza bunge, 1-30 parts of American ginseng and 0.5-20 parts of seabuckthorn flavone. The gingko, the salvia miltiorrhiza bunge, the American ginseng and the seabuckthorn flavone are comprehensively mixed to achieve the effects of convenient use and comprehensive nourishing. The health product of the compound gingko health product solid preparation has values as both food and medicine andcan be used by a patient with a cerebral-vascular disease and a patient with higher blood fat and used for resisting cancer, resisting fatigue, resisting anoxia, resisting radiation, resisting aging,strengthening immunity, and the like by a healthy person. The compound gingko health product solid preparation mainly has two formulations of pills and soft capsules, is convenient for use, is beneficial to absorption and meets the requirement on health by wide consumers.

Disclosed is a use of ethyl p-methoxycinnamate and derivatives thereof in preparing drugs, culture media, regulating agents or cosmetic and skin caring products for maintaining self-renewal and pluripotency of stem cells. The stem cells comprise adult stem cells, embryonic stem cells and induced pluripotent stem (iPS) cells. Also disclosed is a use of ethyl p-methoxycinnamate and the derivatives thereof in in-vitro amplification of stem cells and preparation of induced pluripotent stem (iPS) cells and a use of ethyl p-methoxycinnamate and the derivatives thereof in preparing drugs for treating cell deletion or injury diseases.

Provided is an electrolytic water dispenser. A corrosion-resistant conductive rod is sleeved with a corrosion-resistant conductive pipe sleeve, the two ends of the corrosion-resistant conductive rod exceed a corrosion-resistant conductive pipe, the corrosion-resistant conductive rod is firmly fixed in the center of the corrosion-resistant conductive pipe by two insulation fixing sleeves, the upper end of the corrosion-resistant conductive pipe is sleeved with one end of an upper insulation water guide pipe, a water storage container water outlet pipe is sleeved with the other end of the upper insulation water guide pipe, the lower end of the corrosion-resistant conductive pipe is sleeved with one end of a lower insulation water guide pipe, a water dispenser water nozzle inlet and outlet is sleeved with the other end of the lower insulation water guide pipe, and a heating disc and a temperature sensing head are both arranged in a water storage container. The electrolytic water dispenser has the technical advantages that pulse electrolysis is adopted, so sterilization and disinfection can be achieved under normal temperature, energy can be greatly saved, mineral substance microelements in water can be reserved, and multiple microelements can also be added to water; the electrolytic water dispenser does not need to be cleaned, cleaning expenses in the later period can be greatly saved, and a lot of trouble can be omitted; alkalescence strong activity health care drinking water containing multiple microelements can be made.

The invention described herein is directed to copper-containing compounds for the treatment of toxin exposure (including pore-forming toxin exposure) in a subject in need thereof. The invention is further directed to methods of treating toxin exposure in a subject in need thereof.

A method for producing therapeutic vaccine which consist of NMDA-NRI subunit expressed in insect cells to produce recombinant protein which was encapsulated in PLGA or poly(lactide-co-glycolic acid) microparticles by solvent exchange and used for oral immunization. Excitotoxicity (i.e., a process in which an excessive amount of extracellular glutamate overexcites glutamate receptors and harms neurons) is the common cause involved in a number of neurodegenerative disorders such as Alzheimer's, Parkinson's, Huntington's, Amyloid lateral sclerosis (ALS) and neurological conditions such as stroke, traumatic brain injury, Epilepsy. Thus the experimental model for stroke has been developed for the study of powerful N-methyl-d-aspartic acid (NMDA) NRI subunits, their protective and therapeutic potential for treatment of the neurodegenerative disorder Huntington's in animals and its practicability for therapy in humans.