384 results about "Single variable" patented technology

A processing system having a processing chamber that includes a substrate holder and an electrode. The processing system can include a pressure control system, gas supply system, and monitoring system. A multi-frequency RF source is coupled to the electrode using a reduced-element matching network having a single variable element. The multi-frequency RF source is set to a first frequency to ignite a plasma and to a second frequency to maintain the plasma.

The present invention relates to a simple method for generating antibody-based structures suitable for in vivo use. In particular, the invention relates to a method for the generation of antibody-based structures suitable for in vivo use comprising the steps of: (a) selecting an antibody single variable domain having an epitope binding specificity; and (b) attaching the single domain of step (a) to an effector group. Uses of molecules generated using the method of the Invention are also described.

Video coding efficiency is improved by jointly coding the x and y components of motion vectors with a single variable length code. The motion vector components for a block of pixels are predicted based on motion vectors of neighboring blocks of pixels. The predicted x and y components are then jointly coded by assigning a single variable length code corresponding to the pair of components, rather than a separate code for each component. If the x and y components do not have a corresponding entry in the coding table, they are coded with an escape code followed by fixed length codes.

Video coding efficiency is improved by jointly coding the x and y components of motion vectors with a single variable length code. The motion vector components for a block of pixels are predicted based on motion vectors of neighboring blocks of pixels. The predicted x and y components are then jointly coded by assigning a single variable length code corresponding to the pair of components, rather than a separate code for each component. If the x and y components do not have a corresponding entry in the coding table, they are coded with an escape code followed by fixed length codes.

A model-free adaptive controller is disclosed, which uses a dynamic artificial neural network with a learning algorithm to control any single-variable or multivariable open-loop stable, controllable, and consistently direct-acting or reverse-acting industrial process without requiring any manual tuning, quantitative knowledge of the process, or process identifiers. The need for process knowledge is avoided by substituting 1 for the actual sensitivity function .differential.y(t) / .differential.u(t) of the process.

A stub tag in source code of a webpage allows for collection of numerous data elements according to tracking tags of various data receiver parties and for distribution of the collected data elements to those parties. The stub tag references a remotely cached script that enables a user device, e.g. a computer running a web browser, to retrieve a tag code for collecting the data elements. The tag code is constructed according to data collection settings, data distribution settings, data receiver settings, and / or user privacy settings. The tag code results in a single variable, common to all data receiver parties, for each data element. The common variable is transmitted to data receivers through the user device or through a server-to-server API.

An embodiment of a method for optimizing a solution set has steps of generating a first solution set, selecting a second solution set from the first, fitting the second solution set with a probabilistic model, using the model to generate a new set of solutions, replacing at least a portion of the first set of solutions with the third, and evaluating the third set to determine if completion criteria have been met. A probabilistic model may allow for merging a plurality of variables into a single variable and for modeling relationships between the merged variables over multiple hierarchical levels. Invention method embodiments may also comprise steps of niching to preserve diversity among the solution set.

Bispecific binding molecules, in particular immunoglobulin single variable domains such as VHHs and domain antibodies, comprising a VEGF-binding component and a Dll4-binding component in one molecule. Pharmaceutical compositions containing same and their use in the treatment of diseases that are associated with VEGF- and Dll4-mediated effects on angiogenesis. Nucleic acids encoding the bispecific binding molecules, host cells and methods for preparing same.

An absolute proportioning pumping system includes an electric motor assembly powering a first pump at a first flow rate and powering a second pump at a second flow rate. A proportioned fluid output includes a first fluid pumped by the first pump and a second fluid pumped by the second pump. The pumping system provides a desired ratio of the first fluid to the second fluid at the proportioned fluid output, relatively independently of pressure and flow rate at the output. In accord with further embodiments, a pump and motor assembly is mounted to and generally surrounded by a liquid tank. The pump and motor assembly may include a pair of fixed ratio outputs driven from a common motor, or may include a single variable output pump either slaved to a master pump or controlled through a timed bypass valve to control output flow rate.

The invention relates to a constant-volume firebomb system for simulating combustion of an engine, for solving the technical problems of difficult observation of a flame combustion process in an actual engine, difficult evaluation and determination of a charcoal smoke generation amount at certain time in the combustion process and difficult realization of real-time sampling analysis of combustion products under the condition of a single variable. The constant-volume firebomb system for simulating the combustion of the engine comprises the following components: a firebomb body with a cylindrical cavity; a heating interlayer nested in the periphery of the firebomb body; a fuel injector; a pressure sensor; a temperature sensor; an air inlet channel; an exhaust sampling system; a high-pressure injection fuel oil supply system; a synchronization data acquisition system; a highs-speed shooting system; and a single-chip microcomputer control system. The constant-volume firebomb system provided by the invention has the following advantages: compared to a specially reconstructed single-cylinder machine or a rapid compressor, the cost is lower, and accurate control of the single variable is easily realized.

The invention discloses a detection method of an abnormal event of multi-variable water quality parameter time sequence data. The detection method comprises the following steps: firstly, inputting a plurality of water quality parameter models; training and constructing a data driven predication model (BP model); analyzing multi-variable water quality time sequence data in a water supply pipe net and estimating the model; secondly, predicating through the BP model to obtain a predicated value of water quality data; comparing an actually measured value of a current state and the predicated value obtained by the predication model and carrying out error estimation and classification analysis, so as to determine a single-variable parameter abnormal event; classifying based on an error counting result, and updating and determining the event probability of single-variable water quality parameters through sequential Bayesian updating; carrying out multi-variable fusion decision-making and fusing information from a plurality of water quality monitoring indexes; providing a unified decision-making result and determining whether the water supply pipe net has the abnormal event on a specific node or not.

A stub tag in source code of a webpage allows for collection of numerous data elements according to tracking tags of various data receiver parties and for distribution of the collected data elements to those parties. The stub tag references a remotely cached script that enables a user device, e.g. a computer running a web browser, to retrieve a tag code for collecting the data elements. The tag code is constructed according to data collection settings, data distribution settings, data receiver settings, and / or user privacy settings. The tag code results in a single variable, common to all data receiver parties, for each data element. The common variable is transmitted to data receivers through the user device or through a server-to-server API.

The invention relates to a method for controlling drive pulses of a DAB type bidirectional isolation DC-DC converter. The method for controlling the drive pulses of the DAB type bidirectional isolation DC-DC converter comprises the steps of firstly, carrying out drive pulse control on the DAB type bidirectional isolation DC-DC converter based on a drive pulse working principle; and then inferring relevant formulas in the mode of control, and carrying out characteristic analysis and verification. The method for controlling the drive pulses of the DAB type bidirectional isolation DC-DC converter only needs to control a single variable, is simple and practical, applicable to the state of light load of a system, simple in algorithm, convenient to achieve, and prone to feedback regulation, reduces stress of devices, and effectively improves system efficiency when the system is in light load.

The invention provides a method for on-line measurement of coal quality characteristics based on partial least squares method. Firstly, the coal calibration samples containing known components are detected by use of an laser-induced breakdown spectroscopy (LIBS) system, the calibration samples are classified by the principal component analysis (PCA) or partial least squares-discriminant analysis (PLS-DA) method according to the obtained spectral line intensity matrix, and PLS regression equations of the individual classes of the calibration samples are established respectively; and then a sample to be tested is detected on line to obtain an LIBS spectrum, the type of the sample to be tested is judged by the PCA or PLS-DA method, and the spectral line intensity matrix of the LIBS spectrum is put into the PLS regression equation of the corresponding type to calculate the mass concentrations of individual elements in the sample to be tested. The method fully utilizes the effective information of the LIBS spectrum, eliminates the multiple correlation of spectral line intensity caused by the mutual interference of the elements, reduces the influence of the matrix effect, and is characterized by high goodness of fit, strong reproducibility and high prediction accuracy in comparison with the single-variable calibration method in the prior art.

The invention relates to ligands, such as immunoglobulin single variable domains, that have binding specificity for a receptor. Preferably the receptor is a cell surface receptor and / or the ligand inhibits the activity of the receptor.

In one aspect, the invention relates to a method suitable for administering protein therapeutic molecules orally, sublingually, topically, intravenously, subcutaneously, nasally, vaginally, rectally or by inhalation so as to avoid inactivation, by using VHH polypeptides derived from Camelidae antibodies. The invention further relates to the said therapeutic molecules. The invention further a method for delivering therapeutic molecules to the interior of cells. The invention further relates to anti-IgE therapeutic molecules.In one aspect, the present invention relates to a method wherein an immunoglobulin single variable domain (such as a Nanobody) and / or construct thereof are absorbed in pulmonary tissue. More particularly, the invention provides systemic delivery of an immunoglobulin single variable domain and / or construct thereof via the pulmonary route.

The present invention relates to drug fusions that have improved serum half lives. These fusions and conjugates comprise polypeptides, immunoglobulin (antibody) single variable domains and GLP and / or exendin molecules. The invention further relates to uses, formulations, compositions and devices comprising such drug fusions and conjugates.

Ang2-binding molecules, preferably Ang2-binding immunoglobulin single variable domains like VHHs and domain antibodies, pharmaceutical compositions containing same and their use in the treatment of diseases that are associated with Ang2-mediated effects on angiogenesis. Nucleic acids encoding Ang2-binding molecules, host cells and methods for preparing same.

The invention belongs to the technical field of cigarette production, and particularly relates to a cigarette manufacturing quality stability evaluation method. The method mainly comprises steps of firstly, carrying out hierarchical classification on cigarette quality stability according to manufacturing processes of cigarettes; then, carrying out quantization representing on single-factor variables on a machine bench and carrying out weight assignment; evaluating manufacturing quality stability of a single machine bench, wherein the evaluation result of the machine bench is equal to the weighted average of a single-factor evaluation result; and finally, carrying out stability evaluation on batch manufacturing quality and judging the evaluation result. According to the invention, stability of a single variable in the manufacturing process can be evaluated; quality stability of the machine bench and stability of batch comprehensive quality can be evaluated; cigarette manufacturing level can be improved; and powerful support is provided for improving of product quality stability.

The invention discloses a cigarette quality evaluation method and system based on principal component analysis. The cigarette quality evaluation method and system solves the problem that an existing single-variable evaluation method cannot carry out procedure quality evaluation on multiple-variable procedures. The cigarette quality evaluation method and system uses a principal component analysis method to evaluate processing quality of the multiple-variable procedures and can provide basis for comprehensively grasping procedure quality processing states and procedure quality improvement. The method comprises the steps of firstly, calculating process capability indexes of all processing parameters, then using the principal component analyzing method to analyze all processing parameter data, confirming the number of principal components according to the principle that the accumulative total contribution rate is larger than or equal to 90%, confirming weights of all components according to the explanation variances of all principal components, and finally using an arithmetic weighting method to obtain procedure comprehensive process capability indexes. The cigarette quality evaluation method and system can provide more comprehensive and objective results and provides an effectively tool for an enterprise to know procedure total processing quality situations.

Systems and methods for reading out the states of superconducting flux qubits may couple magnetic flux representative of a qubit state to a DC-SQUID in a variable transformer circuit. The DC-SQUID is electrically coupled in parallel with a primary inductor such that a time-varying (e.g., AC) drive current is divided between the DC-SQUID and the primary inductor in a ratio that is dependent on the qubit state. The primary inductor is inductively coupled to a secondary inductor to provide a time-varying (e.g., AC) output signal indicative of the qubit state without causing the DC-SQUID to switch into a voltage state. Coupling between the superconducting flux qubit and the DC-SQUID may be mediated by a routing system including a plurality of latching qubits. Multiple superconducting flux qubits may be coupled to the same routing system so that a single variable transformer circuit may be used to measure the states of multiple qubits.

An adaptive and synergic fill welding method and apparatus enables automatic, or adaptive fill, and user directed, or synergic fill, modes to provide improved fusion quality, by ensuring that base metal dilution of a weld remains within a predetermined range. The apparatus includes a means for profiling and tracking a joint, and multi-part adjustable welding means. In adaptive fill mode the method automatically varies a plurality of welding parameters in response to measured variations such as joint width between work pieces. In synergic fill mode, the method enables a user to vary multiple welding parameters in response to joint variations by adjusting a single variable, a synergic fill number, which may be controlled by means of a user interface pendent. The multiple welding parameters may include predetermined wire feed speed, torch travel speed, welding voltage and current, torch oscillation width, dwell time, and a plurality of bead size parameters.

The present invention relates to dimers comprising a first polypeptide and a second polypeptide, wherein each of said first and second polypeptide comprises at least one immunoglobulin single variable domain (1ISVD) and a C-terminal extension comprising a cysteine moiety (preferably at the C-terminus), wherein said first polypeptide and said second polypeptide are covalently linked via a disulfide bond between the cysteine moiety of said first polypeptide and the cysteine moiety of said second polypeptide, in which the dimer outperformed the benchmark constructs, e.g. cognate multivalent and multispecific constructs, in various assays. The present invention provides methods for making the dimers of the invention.

The invention discloses a multi-variable flood recurrence period calculating method considering reservoir flood routing calculation. The method is characterized in that symbolic regression is carried out to calculate an explicit representation through genetic programming; a joint probability density function is calculated through a Copula function; then the joint probability density function is subjected to integral operation in a safe area to obtain cumulative probability of the specified annular maximum water level, and finally single-variable recurrence period of the specified annular maximum water level can be calculated as the multi-variable flood recurrence period under the consideration of the reservoir flood routing calculation. According to the method, the reservoir flood routing calculation is considered; a dangerous area is defined based on the annular maximum water level isoline, and thus the hydrological failure mechanism of a reservoir dam can be accurately expressed; the method is applicable to flood dispatching rules at any complexity degree, and scientific and reasonable basis can be provided to the flood control safety design of a reservoir.

Technologies for executing a serial data processing algorithm on a single variable length data buffer includes streaming segments of the buffer into a data register, executing the algorithm on each of the segments in parallel, and combining the results of executing the algorithm on each of the segments to form the output of the serial data processing algorithm.

Bispecific binding molecules binding to both VEGF and Ang2, preferably in the form of immunoglobulin single variable domains like VHHs and domain antibodies, pharmaceutical compositions containing the same and their use in the treatment of diseases that are associated with VEGF- and / or Ang2-mediated effects on angiogenesis are disclosed. Further, nucleic acids encoding bispecific binding molecules, host cells and methods for preparing same are also described.