73results about How to "Delay recession" patented technology

The invention relates to methods and compositions for the treatment or prevention of protein conformation disorders. In particular, the invention relates to an LSD1 inhibitor for use in treating or preventing a protein conformation disorder, such as, e.g., Huntington Disease.

A sintered magnet body (RaT1bMcBd) coated with a powder mixture of an intermetallic compound R1iM1j, R1xT2yM1z, R1iM1jHk), alloy (M1dM2e)or metal (M1) powder and a rare earth (R2) oxide is diffusion treated. The R2 oxide is partially reduced during the diffusion treatment, so a significant amount of R2 can be introduced near interfaces of primary phase grains within the magnet through the passages in the form of grain boundaries. The coercive force is increased while minimizing a decline of remanence.

The invention discloses a nodular cast iron winding drum high in strength and ductility. Nodular cast iron is composed of, by weight, 3.0-3.3% of C, 3.8-4.2% of Si, Mn smaller than 0.3%, 0.03-0.05% of Mg, 0.01-0.025% of RE, S smaller than 0.02%, P smaller than 0.03%, 0.2-0.3% of Mo, 0.12-0.15% of Ni, 0.003-0.010% of Ca, 0.005-0.010% of Ba, Bi smaller than or equal to 0.003% and the balance Fe and inevitable impurities, wherein the total content of Ca and Ba is greater than or equal to 0.010% and smaller than or equal to 0.020%. The nodular cast iron winding drum is high in strength and ductility and can be used for large or ultra-large engineering equipment. The invention further discloses a preparation method for the nodular cast iron winding drum.

A sealing gasket assembly includes one or more carriers each having an offset flexible stopper portion spaced laterally outwardly away from an offset inner sealing portion that is adjacent an opening or other area requiring sealing between mating members adapted to be clamped together. An optional shim can be disposed adjacent to, and aligned with, the carrier. A resilient sealing material is applied to at least portions of the carrier and / or the shim, such as by screen printing, for example. The gasket assembly can be used advantageously in sealing applications such as those for cylinder heads and blocks, intake or exhaust manifolds, piping or other fluid conveying devices, housings, enclosures, or other situations where relative movement can occur between the members to be sealed to each other.

The invention prepares a sow complex premixing feed based upon the sow physiology characteristic and production disciplines, which takes the natural Chinese herbal medicine extract Xianling spleen extract, yellowcypress extract and viable bacteria preparation and their metabolite as the main raw materials, and is formed by preparing according to the regulating effect philosophy of the nerves-endocrine-immune network theory to the domestic environment. The complex premixing feed does not has any hormones, so that it has the functions of enhanced immunity, regulating endocrine function and the restoration of reproductive function of dams. The invention has significant effectiveness, can effectively delay the physiological function decline of sows to reduce the farm-out rate of sows.

Methods for treating subjects suffering from chronic kidney disease-mineral and bone disorder or other disorders resulting in primary or secondary hyperparathyroidism are described. The methods are effective in reducing serum parathyroid hormone (PTH) levels and calcium levels in patients who undergo hemodialysis. The methods described herein are also effective in slowing the progression of kidney disease and preserving kidney function. Compositions used in the described methods are also provided and comprise calcimimetics which function as agonists of the calcium sensing receptor (CaSR).

A reformer furnace (1), comprising: at least one triple conduit assembly (200), including a flue gas conduit (220) enclosing a reaction conduit (240) enclosing a product gas conduit (260), wherein: the reaction conduit (240) extends between a lower end (244) defining a reaction gas inlet (245), and a closed upper end (242); the product gas conduit (260) extends between an upper end (262) defining a product gas inlet (263), and a lower end (264) defining a product gas outlet (265); the flue gas conduit (220) extends between an upper end (222) defining a flue gas inlet (223), and a lower end (224) defining a flue gas outlet (225); and an annulus (250) between the reaction conduit (240) and the product gas conduit (260) comprises a catalyst (252); a combustion chamber (100) that encloses an approximate upper half (226, 246, 266) of the at least one triple conduit assembly (200) while an approximate lower half (228, 248, 268) thereof resides outside of and below the combustion chamber, and that includes at least one burner (110), disposed inside of the combustion chamber and outside of the flue gas conduit (220), such that the approximate upper half (226) of the flue gas conduit substantially shields the reaction conduit (240) from direct burner flame heat radiation and impingement.

A communication method based on a binary molecular communication model comprises the following steps: first, establishing a communication model based on a binary molecule, wherein after a nanometer machine at a sending side releases a molecule, the molecule carious out Brownian movement in a medium, and a probability density distribution function f(t) of the time required by a molecule moving from the nanometer machine at the sending side to a nano-meter machine at a receiving side distance d far from the nanometer machine at the sending side and a cumulative distribution function F(t) corresponding to the probability density distribution function are described in the description; second, designing a transmission mechanism between the nano-meter machine at the sending side and the nano-meter machine at the receiving mode, wherein, in the binary molecular communication model, molecules with different types are sent in order to represent bit 1 and 0 respectively; and third, implementing communication with high throughput and high efficiency in accordance with the transmission mechanism of the binary molecular communication model in the second step. The invention provides the communication method based on a binary molecular communication model, which has higher throughput and high communication efficiency.

The invention belongs to the field of nutrient health food, in particular to a method for preparing a digestive milk beverage. The method comprises the steps of weighting 5 to 10 weight parts of red dates, 5 to 10 weight parts of Astragalus mongholicus, 5 to 10 weight parts of burdock, 1 to 5 weight parts of pawpaw and 1 to 5 weight parts of walnut, cutting up and mixing uniformly so as to acquire a mixture A, mixing the mixture with water with a weight ratio of 1:5 to 10, cooking for 30 to 60 minutes, filtering so as to acquire the filtrate B, weighting 100 to 200 weight parts of milk and 10 to 20 weight parts of honey, adding in the filtrate B, uniformly mixing, degassing, standing by, sterilizing and packaging so as to acquire the product of the invention. The beverage prepared by using the method of the invention can be easily absorbed by human body, can supply the nutrition constituent required by old people, contain various digestive crude fibers and proteases, can help the alimentary system to decompose protein and fat, can promote the digestion and can efficiently solve the problem that the digesting function of the old people is not strong.

The invention discloses a method for prolonging the service life of an organic light emitting device. The method includes the steps of dividing a display screen into a plurality of sub-regions, calculating a service life influencing factor of each sub-region, calculating the luminance ratio coefficient of each sub-region according to image features and the service life influencing factor of the sub-region, calculating the actual display luminance of the display screen according to the luminance ratio coefficient, and outputting images according to the actual display luminance. The invention further provides a display device. With the service life influencing factors and the image features as considering factors, the luminance ratio coefficients are calculated and luminance processing is conducted, the damage influences on the whole image quality are reduced, high and low gray level mixed sub-regions select to increase or decrease the processing strength according to the simplicity and complexity degree of the images and the positions where the sub-regions are located, the image luminance is adjusted on the premise of ensuring the image quality influences, the recession of the OLED is delayed, and the service life of the OLED is prolonged.

The invention relates to a vermicular cast iron and a manufacturing method of the vermicular cast iron. The manufacturing method comprises steps as follows: preparing furnace burden, melting liquid iron, carrying out vermicularizing treatment and pouring the cast, paving a vermicularizing agent on the bottom of a vermicularizing device and covering a slow-release isolation layer on the vermicularizing layer in a vermicularizing treatment process. The vermicular cast iron prepared by the invention is characterized by small chilling tendency of the vermicular cast iron, small length-thickness ratio of vermicular graphite and good ductility and toughness. With the adoption of the method provided by the invention, the vermicularizing effect of the vermicular cast iron is improved, the range of the vermicularizing rate is decreased, and the vermicularizing declay time is prolonged.

The invention discloses a vermicular graphite cast iron material. The material comprises components in percentage by mass of, 3.0-3.9% of carbon, 2.3-3.0% of silicon, less than or equal to 0.4% of copper, less than or equal to 0.01% of chromium, less than or equal to 0.02% of sulfur, less than or equal to 0.07% of phosphorus, less than or equal to 0.5% of manganese and the balance of iron and inevitable impurities. The vermicular graphite cast iron material is not prone to cracking and good in heat dissipation performance, the tensile strength reaches up to 523 Mpa, and the vermiculation ratereaches up to 95%. The invention further discloses a preparation method of the vermicular graphite cast iron material, a ladle bottom pouring method is adopted, a transfer ladle is placed on one sideof a dam, the transfer ladle contains vermiculizer, inoculant and the like, so the prepared vermicular graphite cast iron material is excellent in performance and high in vermicular graphite rate. Thematerial is advantaged in that the vermicular graphite cast iron is applied to production of brake drums, brake discs, speed reducer shells or molds, so the brake drums, the brake discs, the speed reducer shells or the molds are excellent in performance, and the service life is prolonged.

The invention provides a peanut and walnut milk and a preparation method thereof. The peanut and walnut milk comprises the following raw materials: raw milk, peanut kernel, walnut kernel, chia seeds,momordica grosvenori concentrated liquid, momordica grosvenori powder, a stable emulsifier, a pH regulator, cream hickory nut essence and purified water. The sweetness of the momordica grosvenori concentrated liquid is 30 times as that of saccharose, and heat is not generated, and thus momordica grosvenori has effects of reducing blood glucose, depressing blood fat, resisting aging and beautifying. Dietary fiber in the momordica grosvenori concentrated liquid and the momordica grosvenori powder can promote intestinal tract movement and then facilitate digestion and absorption of walnut milk. The preparation method has high raw material utilization rate and production rate, and the prepared peanut and walnut milk does not have precipitate and oil slick in the process of long-term placement.The emulsion is fine and smooth, moderate in sweetness and long in quality guarantee.

A sealing gasket includes an offset flexible stopper portion spaced laterally outwardly away from an offset inner sealing portion that is adjacent an opening or other area requiring sealing between mating members adapted to be clamped together. Preferably the gasket includes a single layer carrier onto which a resilient sealing material is applied to at least portions of the carrier, such as by screen printing, for example. The gasket can be used advantageously in sealing applications such as those for cylinder heads and blocks, intake or exhaust manifolds, piping or other fluid conveying devices, housings, enclosures, or other situations where relative movement can occur between the members to be sealed to each other.

The invention discloses a pure plant traditional Chinese medicinal preparation for treating myocardial infarction and cardiovascular diseases and a preparation method thereof. The preparation comprises the following traditional Chinese medicinal components by weight: 6-15g of codonopsis pilosula, 6-15g of astragalus membranaceus, 6-15 parts of ligusticum wallichii, 8-15g of liquorice, 8-15g of pseudo-ginseng and 50-150ml of gingko leaf extract. The preparation method comprises the following steps: quenching the traditional Chinese medicinal materials for about 4 hours according to the requirement on dosage and quantity; uniformly stirring, adding the gingko leaf extract, and mixing; pouring the mixture in a traditional Chinese medicament extraction bag, putting the bag in a high-pressure kettle, and gradually heating to 105-115 DEG C; cooling to 100 DEG C in the high-pressure kettle, sealing and filling the liquid medicine into a finished product with 50-100ml in each bag to obtain the solution preparation; and storing at normal temperature. The pure plant traditional Chinese medicinal preparation can be used for improving micro-circulation of a human body, eliminating oxygen radicals, remarkably increasing the heart coronary blood flow, remarkably promoting brain blood circulation, increasing brain blood flow rate and regulating blood fat, so that the blood viscosity can be reduced, blood circulation can be improved, and the aging process of a human body can be delayed. The pure plant traditional Chinese medicinal preparation adopts pure plant traditional Chinese medicinal materials, is restrict in formula, mild in action, low in cost and small in dosage, gradually plays drug effects, and does hurt the liver or kidney of a patient.

The invention relates to the field of animal husbandry and veterinary and particularly discloses a method for delaying the reproduction function decline of female animals, wherein the animals take in melatonin through oral administration. The delaying of the reproduction function decline of female animals is shown by increasing the litter size of older female animals, the SOD level of ovary, the SOD level of uterus, the number of useful eggs, total egg number, cleavage rate or blastocyst rate or reducing the MDA level of the ovary of older female animals, the MDA level of uterus or the number of useless eggs. In the invention, through a large quantity of objective experiments, different optimal intakes are provided aiming at reproduction function decline of specific different female animals so as to realize the best effect of delaying the reproduction function decline of female animals.

A therapeutic method for preserving the dopaminergic function of patients suffering from Parkinson's disease, which method comprises administering an effective amount of ropinirole or a pharmaceutically acceptable salt or solvate thereof to a human or animal patient in need thereof. Typically, said patient has had Parkinson's disease for a period of less than three years since diagnosis. Preferably the invention comprises administering to said patient an effective amount of ropinirole or a pharmaceutically acceptable salt or solvate thereof, optionally in combination with one or more other dopamine agonists, in the absence of levodopa or any other dopamine precursor, and thereafter treating the patient with levodopa.

The present invention relates to multi-arm star macromolecules which are used as thickening agents or rheology modifiers, including use in hydraulic fracturing fluid compositions. In one aspect of the invention, a star macromolecule is capable of thickening via a dual mechanism comprising (1) self-assembly of the hydrophobic polymerized segments of the star macromolecules via hydrophobic interactions or associations, and (2) association, reaction, or combination of the hydroxyl-containing polymerized segments of one or more of the star macromolecules.

A door mirror is disposed at a side of a vehicle body, and the door mirror includes a mirror body that is provided at a tip of a door mirror stay extending from the side of the vehicle body in at least one of a width direction and a vertical direction of the vehicle body, and an actuator that changes an interval between the vehicle body and the mirror body. The mirror body is actuated in accordance with at least any of a traveling environment and a passenger state.

The invention discloses a leg muscle group exercising device which is characterized by comprising springs and protecting plates. The protecting plates comprise a left protecting plate and a right protecting plate. The left protecting plate and the right protecting plate are connected through the springs and provided with fixing bands respectively. The protecting plates are provided with protecting pads and are in an arc shape. Buckles of the fixing bands are snap fasteners or hook and loop fasteners. The springs are compression springs or extension springs or telescopic springs. The number of the springs is one to three. The springs are detachably connected with the protecting plates. The leg muscle group trainer is low in cost, convenient to carry and use and good in exercising effect, and allows a user to take exercise anytime and anywhere.

The invention relates to vermicular graphite cast iron and a manufacturing process thereof. The manufacturing process sequentially comprises the steps of furnace charge preparation, iron liquid smelting, vermicularizing treatment and casting pouring. In the vermicularizing treatment process, vermicularizer partners are added, and comprise the following elements in parts by weight: 11 to 14 parts of Ca, 4 to 7 parts of Ba, 18 to 23 parts of Sb or Bi, 5 to 8 parts of C, 43 to 48 parts of Si and 9 to 13 parts of Fe. The obtained vermicular graphite cast iron is low in chilling tendency and high in ductility and toughness, and the slenderness ratio of vermicular graphite is lower (namely the vermicular graphite seems thick). The vermicularizing effect of the vermicular graphite cast iron is improved, and a vermicularizing rate range is reduced.

The invention discloses an Internet-based system and method for screening, evaluation and rehabilitation training of cognitive disorder. The system comprises: a quick screening module, which is used for conducting quick screening to obtain quick screening data so as to achieve quick preliminary screening of completely healthy people, suspected mild and moderate people with cognitive disorder, andsuspected severe people with cognitive disorder; a remote consultation module, which is used for realizing reservation of remote consultation by suspected mild and moderate people with cognitive disorder, selection and pushing of an auxiliary evaluation scheme and acquiring final remote consultation data; an offline outpatient appointment module, which is used for providing an offline outpatient appointment window for the people with light and medium cognitive disorder confirmed after remote consultation; and a cognitive assessment and rehabilitation training module, which is used for acquiring the rapidly-screened data and the remote consultation data and providing an interactive interface for cognitive assessment and rehabilitation training. The cognitive disorder is rapidly screened inan early stage, meticulous evaluation and diagnosis are carried out through combination of quick screening with remote consultation, and finally, rehabilitation training is carried out through cognitive evaluation and rehabilitation training.