113results about How to "Avoid swallowing" patented technology

The invention provides an ecologically adjustable fish reef ecological floating bed device. The device comprises a floating bed frame, a plurality of fish reef module units and aquatic plants, wherein each fish reef module unit is connected with one another and fixed by the floating bed frame and comprises a grid and an organism ceramsite layer, a fish reef channel layer and a packing layer which are arranged from top to bottom sequentially and are separated from one another by interlayers; the grids surround around the organism ceramsite layers, the fish reef channel layers and the packing layers and the bottoms of the packing layers respectively; fish reef passages are respectively opened around the fish reef channel layers; holes are opened at the position, corresponding to openings of the fish reef passages, of the grids to make the fish reef channel layers communicate with outside; and the aquatic plants are arranged on the organism ceramsite layers. The device can ensure the normal growth and prevent the overgrowth of the aquatic plants at the same time; and meanwhile, a simple food chain of 'organisms-planktons-fishes' is formed inside the device to improve the purifying capacity of water of the device.

The invention provides a long-circulating preparation which is an invisible nano particle, a stealth lipidosome, or an invisible micelle containing docetaxle, carrier materials and additive. The long-circulating preparation is prepared by wrapping the docetaxle with the carrier materials that are modified by polyethylene glycol, a hydrotropic substance. The long-circulating preparation of the docetaxel can avoid being captured or swallowed by the hepatolienal reticular endothelial system in the body, thus prolonging circulation time in blood. Compared with the common injection of the docetaxel or the non-stealth lipidosome of the docetaxel, the long-circulating preparation of the docetaxel provided by the invention has stronger inhibit function on a tumor.

The invention discloses an NT-ProBNP detection kit. The NT-ProBNP detection kit comprises a calibrator, a cleaning solution, a substrate solution, a pretreatment solution, an enzyme conjugate workingsolution and a magnetic bead conjugate working solution; the pretreatment solution contains pyridine, the enzyme conjugate working solution contains NT-ProBNP antibody labeled by enzyme, and the magnetic bead conjugate working solution contains magnetic beads labeled by the NT-ProBNP antibody. The NT-ProBNP detection kit can accurately measure NT-ProBNP in a whole blood sample, the lowest limit detection of the kit is 20 pg / ml, the linearity range is 20-5,000 pg / ml, the detection sensitivity is high, the linearity range is wide, and the result is accurate. The invention further discloses a using method of the NT-ProBNP detection kit. The NT-ProBNP detection kit is simple in using step, the detection time of an NT-ProBNP is shortened, and quick and sensitive detection of the NT-ProBNP is achieved.

The invention relates to the field of pharmacy and provides a preparation method of targeting and photo-thermal integrated erythrocyte bionic nanoparticles. The method comprises the following steps: firstly, extracting erythrocyte membranes, then loading indocyanine green to a polylactic acid-hydroxyl acetic acid solution, burying adriamycin amycin to the system, and preparing an indocyanine greenpolylactic acid-hydroxyl acetic acid solution buried with adriamycin amycin through a secondary emulsification-solvent evaporation method; then carrying out a reaction on folic chitosan oligosaccharide and the indocyanine green polylactic acid-hydroxyl acetic acid solution to obtain an adriamycin amycin-folic chitosan oligosaccharide-indocyanine green-polylactic acid-hydroxyl acetic acid solution; and finally, extruding the adriamycin amycin-folic chitosan oligosaccharide-indocyanine green-polylactic acid-hydroxyl acetic acid solution into the erythrocyte membranes to obtain the erythrocyte bionic nanoparticles.

The invention relates to a turtle pond which comprises a shallow pool, a spawning site, a flower and tree site which is arranged between the spawning site and the shallow pool for planting flowers and trees, turtle houses, feeding troughs and a water discharge chute. The turtle pond meets the ecology habit of land tortoises or semi-aquatic turtles and the structure thereof is scientific and reasonable, economical and practical; by adopting the turtle pond for raising turtles, both the survival rate and the reproduction rate of the turtles can be high.

The invention discloses a novel anti-tumor nano-drug carrier and a preparation method and application thereof. The method comprises the following steps: carrying out an amidation reaction on chitosan and deoxycholic acid to form a copolymer chitosan-deoxycholic acid, forming an intermediate of the chitosan-deoxycholic acid and formaldehyde, carrying out a reaction on the intermediate and polyethylene glycol, carrying out an amidation reaction on the obtained chitosan-deoxycholic acid-polyethylene glycol so as to prepare the novel anti-tumor nano-drug carrier. The characteristics that a folate receptor on the surface of the tumor cells has high expression and the folate receptor hardly has excessive expression in normal tissues are utilized, the novel anti-tumor nano-drug carrier connected with folate and the tumor cells have high affinity, and the defect that the common nanoparticle function is single is overcome. The prepared novel anti-tumor nano-drug carrier can well avoid cytophagy of phagocyte, the carrier circulates in vivo for a long time and is not eliminated, the active targeting modification can be better combined with tumor cell specificity, and the harm of the drug to normal human cells is reduced.

The invention relates to a docetaxel nano preparation and a preparation method thereof. The average grain diameter of the docetaxel nano preparation ranges from 20 nm to 500 nm. The docetaxel nano preparation comprises, by weight, 0.1% to 20% of docetaxel, 65% to 99% of biodegradable carrier material and 0.01% to 15% of stabilizing agent, wherein the stabilizing agent is one or combination of more selected from polyvinylpyrrolidone and ethylene glycol succinic acid ester derivatives. Compared with preparations in the market, the docetaxel nano preparation is higher in stability and longer in cycle time in vivo, can achieve long-time release of medicines, and improves medicine effect. Compared with ordinary nano preparations, the docetaxel nano preparation is more stable, has a larger area under concentration-time curve (AUC), and has stronger inhibitory action on a tumor. In addition, when the docetaxel nano preparation is taken orally, retention time and curative effect which are several times better than ordinary clinical injecta can be achieved, the toxic and side effects are remarkably reduced, and the bioavailability is remarkably improved.

The invention belongs to the field of in-vitro diagnostic reagent kits, and particularly relates to a myoglobin detection reagent kit and a method for applying the same. The myoglobin detection reagent kit comprises calibration products, reagents R1, enzyme conjugate working solution R2, magnetic bead conjugate working solution M, cleaning solution and chemiluminescent substrates. The reagents R1contain imidazole components, blood cells in whole blood can be quickly removed by the imidazole components, and accordingly the possibility that magnetic beads are swallowed by the blood cells can beeffectively prevented; the cleaning solution contains sodium lauryl sulfate components, accordingly, cleaning effects can be enhanced, and non-specific binding of the chemiluminescent substrates canbe prevented. The myoglobin detection reagent kit and the method have the advantages that finger peripheral whole blood or anticoagulant venous whole blood can be directly used as a to-be-detected sample for the myoglobin detection reagent kit, the whole blood sample can be directly detected without being pretreated, accordingly, the detection speed can be greatly increased, operation steps can besimplified, the application range of the myoglobin detection reagent kit can be expanded, and large-scale popularization and application can be facilitated.

An anti-swallow pacifier includes: a base member having nipple member protruding forwardly from the base member, a bivalve shell having a pair of half-shell pieces hingedly secured to the base member having a restoring spring retained on the base member for resiliently automatically closing the two half-shell pieces for covering the nipple portion, an anti-swallow shield circumferentially formed on a rear portion of the base member for preventing from swallow of the pacifier by a baby as the shield may be obstructed beyond the baby's mouth without being swallowed, and a handle secured to the anti-swallow shield.

The invention discloses a cTnI detection kit which comprises a calibration product, a cleanout fluid, a substrate solution, a pretreatment liquid, an enzyme conjugate working solution and a magnetic bead conjugate working solution, wherein the pretreatment liquid contains imidazole; the enzyme conjugate working solution contain an enzyme labeled cTnI antibody; and the magnetic bead conjugate working solution contains cTnI antibody labeled magnetic beads. The cTnI detection kit can realize accurate determination of cTnI in a whole blood sample, the detection steps are simplified, and the detection efficiency is improved. The lowest detection limit of the kit is 0.02ng / ml, the linear range is 0.02-50ng / ml, the detection sensitivity is high, the linear range is wide, and the detection resultis accurate. The invention further discloses a using method of the cTnI detection kit. The using method is simple in using steps, the detection time of the cTnI is effectively shortened, and rapid andsensitive detection of the cTnI is realized.

Compositions and methods for deterring and / or visually identifying oral contact with objects that are hazardous upon oral contact or ingestion are disclosed. The compositions generally comprise a colourant and a carrier and may further comprise an aversive agent, a salivating agent, and / or an emetic. The compositions may be particularly useful for application to batteries, including button cells.

The invention discloses a CK-MB detection kit which comprises calibrator, cleaning fluid, a substrate solution, a pretreatment solution, an enzyme conjugate working solution and magnetic bead conjugate working solution, wherein the pretreatment solution contains imidazole, the enzyme conjugate working solution contains an enzyme marked CK-MB antibody, and the magnetic bead conjugate working solution contains CK-MB antibody marked magnetic beads. By means of the CK-MB detection kit, accurate measurement of CK-MB in a whole blood sample can be achieved, detection steps are simplified, and a detection efficiency is improved. The lowest detection limit of the kit is 1ng / ml, a linearity range is 1 to 300ng / ml, detection sensitivity is high, the linearity range is wide, and detection results areaccurate. The invention further discloses a use method of the CK-MB detection kit. Use steps of the use method are simple, CK-MB detection time is effectively shortened, and quick and flexible detection of the CK-MB is benefit to achieve.

A toothbrush with a safety device includes a brush body and an annular spacer. The brush body includes a bristle portion with a plurality of bristles and a handle portion contiguous to the bristle portion. The annular spacer is flared and includes a smaller end and larger end having a diameter greater than that of the smaller end. The smaller end of the spacer is tightly mounted around the handle portion below the bristle portion. The annular spacer avoids the toothbrush from being swallowed and prevents spit and bubbles generated during brushing from coming into contact with a user's hand.

The invention belongs to the field of in vitro diagnosis kits, and concretely relates to a D-dimer detection kit and a use method thereof. The D-dimer detection kit comprises a calibration product, areagent R1, an enzyme conjugate working solution R2, a magnetic bead conjugate working solution M, a cleaning solution and a chemiluminescent substrate, and the reagent R1 contains an imidazole component, so blood cells in the whole blood can be quickly eliminated to effectively avoid the possibility of blood cells swallowing magnetic beads. The kit can directly use fingertip whole blood or anticoagulant venous whole blood as a sample to be tested, and can directly detect the whole blood sample without preprocessing the whole blood sample, so the detection speed is greatly improved, the operation steps are simplified, the application range of the kit is enlarged, and large-scale promotion and application are easy.

The invention discloses a ridging film-mulching planting method for potatoes. The method comprises the following steps: block dicing and germination, soil selection and preparation, ridging and fertilization, seeding and film mulching, topdressing and management, seedling killing, harvesting and the like. Through film mulching, topdressing and management, yield reduction caused by excessive pestsin a late period and influences, caused by bad quality of the potatoes, on sales and eating are avoided, the moisture condition in soil can be maintained fully, and water can be prevented from evaporating; meanwhile, by arranging micro-ditches for collecting rain, the purposes of drought resistance and water saving are achieved, the potato yield is increased, plants and soil are supplemented withpotassium, supplementation of phosphate fertilizer can also be achieved, and the fertility level of the soil and the quality and yield of the potatoes are improved; when the method is compared an existing technique, the yield of the potatoes is improved greatly, better quality of the potatoes is ensured, eating and pollution by the pests are also avoided, and the method has great practicability and is worthy of promotion and application in the future.

The invention relates to an isolation box for fish propagation. The isolation box comprises a box body provided with a draining opening, an upper isolation net, a rolling shaft, a sliding plate and a driving mechanism, wherein the upper isolation net is transversely arranged in the middle part of the box body and can be used for preventing bred fish from moving to the lower part of the box body; the rolling shaft is detachably arranged in the box body and positioned below the upper isolation net, wherein the rolling shaft is hollow, and the surface of the rolling shaft is a frosted surface and provided with a plurality of through holes of which the diameter is less than fish eggs; the through holes are formed at intervals; a water inlet through which water is fed into the rolling shaft is formed in the rolling shaft; the sliding plate is obliquely arranged between the isolation net and the rolling shaft; the tail end of the sliding plate is correspondingly arranged above the rolling shaft; the driving mechanism is in driving connection with the rolling shaft and can drive the rolling shaft to rotate. According to the isolation box, the fish eggs can be attached on the through holes in the surface of the rolling shaft; the residual foods and the excrement can continuously downwards fall down to reach the bottom part of the box body as the rolling shaft rotates, so that the fish eggs can be conveniently separated from the residual foods and the excrement; the fish eggs can be quickly collected without damage.

The invention discloses an acrossocheilus fasciatus spawning pond. The acrossocheilus fasciatus spawning pond comprises a parent fish pond and a separating pond. A spawn collecting pond is arranged at the bottom of the parent fish pond, a spawning bed is arranged between the parent fish pond and the separating pond and paved with gravel, and gaps are reserved between the gravel so that spawn granules can enter the spawn collecting pond along with water flow and parent fish can be stopped above the spawning bed. A water inlet is formed in the upper portion of the parent fish pond, a drainage spawn collecting pipe is arranged at the bottom of the spawn collecting pond, and a vertical pipe and an inverted-U-shaped pipe are arranged on the drainage spawn collecting pipe. An overflow port is formed in the separating pond, and a spawn taking valve is arranged at the bottom end of the separating pond. According to the acrossocheilus fasciatus spawning pond, after being laid by parent fish in the parent fish pond, spawn granules rapidly penetrate through the spawning bed and enter the spawn collecting pond along with water flow, so that it is avoided that spawn granules are devoured by parent fish; due to the design of the separating pond, zygotes can be easily, conveniently and efficiently collected, the high-intensity operation of fishing for zygotes manually is relieved, and interference with the spawning behavior of parent fish is avoided. The acrossocheilus fasciatus spawning pond is simple in structure and low in cost and saves time and labor, the spawning rate and fertilization rate of parent fish exceed 90%, and the zygote collecting rate reaches 98% or above.

The invention provides an intelligent and multifunctional infant chaperoning system. The intelligent and multifunctional infant chaperoning system is formed by connecting a weeping sound identification module, a random music playing module, a music-playing manual selection module and a body temperature monitoring module, the modules are solidified on a chip and installed in a silicon gel shell which can be bent, and connection between the modules needs to meet the connection relations. The intelligent and multifunctional infant chaperoning system can achieve the functions of identifying weeping sound of an infant and playing music randomly, and can achieve the functions that the body of the infant is monitored and early warning is conducted when the body temperature is abnormal. The shell of the system is a non-hazardous sealed silicon gel device which can not only be wound around multiple portions of the body but also be independently used as an intelligent electric thermometer and a teething stick of the infant.

A pacifier (1) is provided which comprises a nipple (2) and a shield (3) made of an elastic material. The shield (3) comprises two stable mechanical states: one in which the shield (3) acts as a shield and another in which the shield (3) acts as a nipple cover. The shield (3) is transformable from one stable mechanical state to another upon an impact to the shield (3).

The invention discloses a float type feeding device capable of floating or sinking for fish farming. The float type feeding device comprises a barrel and a container in the barrel. The float type feeding device capable of floating or sinking is simple in structure as compared with the prior art; during use, the device sinks in water after enough sinkable feed is added on a floating board, the gravity applied to the floating board is reduced greatly as the feed on the floating board is swallowed by fish, the floating board made of light material raises due to buoyancy of water, water flows in each accommodating cavity as through holes between the floating board and accommodating cavity are opened, buoys are applied with force to drive the container to float, and then feed on the next floating board exposes for feeding fish; after enough floatable feed is added on the floating board, the feed can attach the upper portion of each accommodating cavity and floats along with the container after the accommodating cavity is filled with water, and then fish can eat the feed from below; and meanwhile the feed cannot disperse or spill and accordingly cannot be swallowed by birds. The float type feeding device capable of floating or sinking for fish farming has excellent effect.

The invention discloses an artificial pharynx posterior wall body fluid sampling device. The artificial pharynx posterior wall body fluid sampling device comprises sampling equipment , a mouth opener and a control device, wherein the sampling equipment is used for stretching to a sampling point for sampling, and the mouth opener is used for pressing the tongue of a sampled person so that the sampling equipment can clamp a cotton swab to the sampling point; the sampling equipment comprises a machine body and a cotton swab loading and unloading device arranged at the front end of the machine body; the control device is used for controlling sampling, and the control device comprises an inertial measurement unit arranged on the machine body, a central processing unit, a storage unit for storing information, an image acquisition device arranged at the end part of the machine body and used for acquiring images of the pharynx posterior wall body of the detected person, and a display device for displaying the images. The artificial pharynx posterior wall body fluid sampling device has the advantages of simple structure and convenient operation, operation errors and leak detection can be effectively reduced, and the detection accuracy is improved.

Compositions and methods for deterring and / or visually identifying oral contact with objects that are hazardous upon oral contact or ingestion are disclosed. The compositions generally comprise a colourant and a carrier and may further comprise an aversive agent, a salivating agent, and / or an emetic. The compositions may be particularly useful for application to batteries, including button cells.

The invention discloses a feed throwing prompting device for fish feeding. Compared with the prior art, when in use, water in a pool enters the upper space of a feed box and flows into the lower spaceof the feed box through through holes, when the weight of the upper feed is reduced to a certain weight, the feed box floats upwards and opens the lower space of the feed box for fish to swallow, when the feed box is completely lifted to the upper position, lifting mechanisms in cavity chambers are lifted and a first water inlet hole is opened, water flows into a partition wall and lifts a lifting plate to open up the left and right cavity chambers for fish to swallow the feeds in each chamber, after the feeds are swallowed, fish fries enter in to the left cavity chamber, the feed in the leftchamber is used as a buffer, after the left lifting mechanism floats out, a breeder can add and clean the feed in the left lifting mechanism, the right lifting mechanism, and the lifting plate and the left lifting mechanism float out of the water surface in sequence for the breeder to record the time required for feeding in the device and the rise of all floating mechanisms, so that the use is more reasonable.

The invention provides a holothurian culture device capable of simultaneously culturing laver and a method for culturing holothurians and laver by utilizing the device. The device comprises a housing, a first partition plate, a holothurian culture zone and a laver culture zone are arranged in the housing, the holothurian culture zone is arranged above the laver culture zone, the holothurian culture zone and the laver culture zone are partitioned through the first partition plate, a second partition plate is arranged above the first partition plate and is provided with a charging hole, and a laver culture raft rack is arranged below the first partition plate. The holothurian culture zone is provided with a water inlet, and the laver culture zone is provided with a water draining port. The holothurian culture device further comprises a sunshade, wherein the sunshade comprises sun-shielding cloth, the sun-shielding cloth is arranged above the housing, and a solar cell panel is arranged above the sun-shielding cloth. The holothurian culture device has the advantages that the holothurian culture zone is arranged above the laver culture zone, holothurians and laver are separated by the first partition plate, so that the holothurians and laver can be cultured simultaneously, and excrement produced in holothurian culture can be utilized by the laver and promotes laver growth.

The invention discloses a terpolymer shown as the general formula (I), wherein x is 2, 4 or 6, y is 0, 2 or 4, m is an integer between 10 and 100, and n is an integer between 20 and 80. The amphiphilic triblock copolymer has excellent biocompatibility and capability of being partially biodegradable, and can form a nano medicine carrier with a structure imitating a cell outer membrane in water by self-assembly. The amphiphilic triblock copolymer has important research value and a broad application prospect in the field of controlled release of medicines. (I).

The invention discloses a kelp cultivation device and method. The device comprises a water tank, the upper end of one side of the water tank is connected with a water inlet pipe, the lower end of the other side of the water tank is connected with a water outlet pipe, a first connecting plate is fixedly installed at the upper end of the water tank, a plurality of swinging devices are evenly installed on the first connecting plate, and supporting rods are fixedly installed on the two sides of the upper end of the first connecting plate. The upper ends of the two supporting rods are connected through a second connecting plate, each swing device comprises a fixing frame, one side of each fixing frame is fixedly connected with one side of the first connecting plate, a connecting rod and a first fixing block are fixedly installed on the two sides of the upper end of each fixing frame correspondingly, a second fixing block is fixedly installed on one side of the upper end of each connecting rod, and a first sleeve is arranged on each first fixing block in a penetrating and inserting mode. A second sleeve is arranged on each second fixing block in a penetrating and inserting mode, the right end of the first sleeve is sleeved with a first movable plate, a first fixed pipe is arranged at the end, away from the first sleeve, of the first movable plate in a penetrating and inserting mode, a second movable plate is arranged at the lower end of each second sleeve, and a second fixed pipe is arranged at the upper end of the side, away from the second sleeve, of each second movable plate in a penetrating and inserting mode.

The invention discloses an integrated electric toothbrush with flushing function; the electric toothbrush comprises a brush head, a brush rod, a brush handle, a flushing mechanism for spraying the rinsing liquid to the brush head, a negative pressure suction mechanism for sucking the residual liquid after rinsing with negative pressure, and a driving mechanism for controlling the movement of the brush head; the electric toothbrush has the advantages that: because the flushing mechanism is arranged, adding rinsing liquid is facilitated when the medical staff is brushing the teeth of a patient.Because the negative pressure suction mechanism is arranged, suction of residual and waste liquid from the mouth of the patient is facilitate, so that the mouth of the patient can be cleaned better. Because the driving mechanism is arranged, automatic cleaning of the teeth of the patient is facilitated. Because the brush head includes multiple silicone bristles, the electric brush has good softness without causing damage to the gum tissue of the patient. The trouble of brushing the teeth of the patient by manual swing is avoided, thereby saving time and labor and greatly reducing the working load of the medical staff, and also, the use effect of the electric brush is good.

The invention discloses a periodontitis treatment device, and the device comprises a power supply control system and an infrared generation element, and also comprises iontophoresis electrodes. The infrared generation element is buried in an elastic concave body, wherein an outer side of the elastic concave body is matched with the inner sides of the teeth and a gum, and clamping grooves are disposed nearby the upper and lower edges of the inner side. When the device is in use, the device irradiates the gingiva from the inside to the outside. The iontophoresis electrodes are divided into an inner electrode and an outer electrode according to the position of iontophoresis electrodes relative to the oral cavity when the iontophoresis electrodes are in use. The inner electrode is shaped liketwo arches, and is made of stainless steel at a 304 food level, and is embedded into the clamping groove at the inner side of the elastic concave body. The outer electrode is shaped like a concave plate, and when the outer electrode is in use, the outer electrode is located at an outer side of a lip and covers the positions of the teeth and gum, and can be made of an iontophoresis electrode material. The power supply control system is disposed in a battery box which is adjacent to the outer electrode, and is provided with an infrared irradiation output end and an iontophoresis output end, wherein the iontophoresis output end is fixedly and electrically connected with the inner and outer electrodes. The iontophoresis output end is electrically connected with the inner and outer electrodes in a replaceable manner.