The invention relates to a manufacturing technique for energy regeneration and non-waste comprehensive utilization of municipal domestic waste, which is characterized by comprising the steps of waste classification, pretreatment and treatment of nonmetallic inorganic substances, schizolysis, filtration and reforming of organic substances, synthesis of fuel oil and treatment of organic substance byproducts. The manufacturing technique completely treats waste, has no secondary pollution during the whole treatment, and really realizes complete conversion and utilization of the waste. When the technology is used for treating organic substance waste and so on, including organic substance parts of the municipal domestic waste and various animal and plant waste, not only the environmental problem caused by the municipal domestic waste and the waste problem of the waste can be solved but also energy and slow release fertilizer which returns to earth can be efficiently generated, so that green circulation of renewable energy resources is realized. The applied proposal has reasonable energy consumption in the whole process, has no pollution, has controllable products, high output value and stable and reliable sources of raw materials, and realizes sustainable development.