193 results about "Vitamina D2" patented technology

An filamentous fungi is disclosed with a naturally vitamin D enriched nutritional profile. These enriched mushrooms were shown to have a synergistic effect on longevity of subjects with both a normal and nutritionally deficient diets, improved tolerance to oxidative stress, and increased longevity in a Alzheimer's disease model. Surprisingly, vitamin D2 and D3 fed alone or in combination with nonenriched mushrooms did not produce similar effects.

The embodiment of the invention provides a method for detecting 25(hydroxyl)vitamin D by using a high-pass liquid chromatography-tandem mass spectrometry. The method comprises the following steps of: adding an acetonitrile solution containing an internal standard substance of the 25(hydroxyl)vitamin D into a human serum sample to carry out protein precipitation; sufficiently and uniformly mixing the solution, and then, adding an n-hexane extracting solvent; sufficiently and uniformly mixing the solution, then centrifuging the solution, movably taking a supernatant and drying the supernatant, and adding a complex solution to obtain a sample to be detected; detecting the sample to be detected by using a high-pass liquid chromatography-tandem quadrupole mass spectrometer; and quantifying according to the relative retention time of 25(hydroxyl)vitamin D2 and/or 25(hydroxyl)vitamin D3 and the detected abundance ratio of quantitative ion pairs by using an internal standard curve method. According to the embodiment of the invention, the method has the advantages of simplicity in pretreatment, strong specificity and matrix interference resistance, short detection time, high pass, high detection precision and low cost.

The present invention relates to novel yeast. More specifically, a novel yeast that is enriched for Vitamin D. In one aspect, the invention comprises a yeast that retains its gassing power after UV irradiation and that can be used to produce breads and other baked products with significant levels of vitamin D, in particular Vitamin D2. The invention also relates to a method of producing a novel D2 enriched yeast as well methods of using the novel yeast of the invention.

The present invention discloses methods for preparing vitamin D2 derivatives and intermediates of vitamin D2 derivatives. The present invention discloses an improved photolysis process for the preparation of cis intermediates (I) from trans starting materials (II). Also disclosed is an improved method for the formation of a trans double bond at C22-C23 of a vitamin D2 derivative, which has a negative effect on the desired cis double bond of compound (IIIA) relative to the undesired cis double bond of compound (IIIA). The trans double bond provides high selectivity.

The invention relates to a natural fluorine-free edible transparent child nutrition toothpaste, belonging to the daily necessities technical field. The natural fluorine-free edible transparent child nutrition toothpaste of the invention is made by adhesive, foaming agent, moisturizer, sweetener, abradant, perfume, deionized water, preservative, hydrolyzed pearl solution, milk calcium, zinc gluconate, vitamin E acetate and vitamin D2 according to the conventional method. The vitamin E acetate, xylitol, hydrolyzed pearl solution, milk calcium, zinc gluoconate and vitamin D2 in the invention act combinedly, oral odour and bacteria can be effectively cleared away, periodontitis and gingivitis can be prevented and treated, caries preventing effect is obvious, and tooth calcification capability can be improved. Nutrition health care function on deciduous teeth of children of two to five can be realized.

The present invention belongs to the field of health food, and in particular relates to a vitamin D3 soft capsule and a preparation method thereof. The vitamin D3 soft capsule includes an internal contained substance and a capsule shell, the internal contained substance comprises the following components in parts by weight: vitamin D3, vitamin D2, walnut oil, eucommia ulmoides seed oil, pomegranate seed oil, amino acids, calcium citrate, an antioxidant and a stabilizer; and the capsule shell comprises the following components in parts by weight: gelatine, glycerol, titanium dioxide, and purified water. The vitamin D3 soft capsules contains a variety of vitamins and vegetable oils, can be used for supplement of a sufficient amount of vitamin D and promotion the absorption of calcium and phosphorus, can provide a variety of nutrients for the human body, and has the effects of enhancing brain function, enhance human immune function, promoting the development of the brain and nervous system, eliminating free radicals in the body, preventing a variety of chronic diseases, and the like.

The invention discloses a fat-soluble composite vitamin I composition freeze-dried powder injection. The fat-soluble composite vitamin I composition freeze-dried powder injection is safe and reliable, has stable quality and is prepared from vitamin A palmitate, vitamin K1, vitamin E, vitamin D2, povidone, propyl gallate, polysorbate 80, mannitol and injection water. The fat-soluble composite vitamin I composition freeze-dried powder injection and the preparation method thereof thoroughly solve that the existing fat-soluble composite vitamin freeze-dried powder injection can not be stored for a long time and the content of related substances is very high and can not be controlled so that injection safety problems and active substance degradation problems are caused. In the clinical use, the fat-soluble composite vitamin I composition freeze-dried powder injection is safe, has stable quality and can be stored for a long time.

An apparatus and method for increasing Vitamin D content in mushrooms irradiates the mushroom(s) for a duration of up to six seconds with one or more pulses of light with wavelengths in the range of about 200 to about 1000 nanometers. The light is emitted by an electric glow discharge lamp, such as a xenon lamp, that emits ultra-violet light. The intensity of the light is such that after irradiation the mushrooms have a Vitamin D2 content of at least about 400 IU/84 g of mushrooms, which is 100% Daily Value of recommended Vitamin D for human consumption.

The present invention relates to a preparation method of C1-hydroxy-C24-hydroxy-vitamin D derivative, in particular said invention relates to a method capable of utilizing vitamin D2 as initial raw material to respectively prepare calcipotriol compound and tacalcitol compound. Besides, said invention also provides the concrete steps for synthesizing above-mentioned two compounds.

A health-care nutrients softgel for gravida is prepared from 22 nutrients including VC, nicotinamide, VE, pantothenic acid, VB6, VB1, Vb2, beta-carrotin, folic acid, VD2, etc.

The invention relates to a stable composite fat-soluble vitamin composition and an injection and a preparation method thereof. The composition comprises vitamin A palmitate or analogue thereof, vitamin E or analogue thereof, vitamin K1 or analogue thereof, vitamin D2 and medically acceptable adjuvants, wherein the medically acceptable adjuvants comprise an acidity buffering agent. The injection is prepared by using aseptic filtration and an aseptic production process or a freeze drying process. Compared to the prior art, the composition provided in the invention has better stability and makes substantial progress.

Nutritional products, compositions, functional ingredients, medical foods, pharmaceutical preparations and methods of use are disclosed for support and improvement of athletic performance (strength, flexibility, endurance, balance, and conditioning), and prevention and repair of injuries, including improving or maintaining muscle mitochondrial health, stimulating muscle mitochondrial biogenesis as well as other indications as set forth herein. In addition, pharmaceutical, nutraceutical and nutritional medical food compositions that are useful in conditions, normal or abnormal, associated with mitochondrial dysfunction and altered biogenesis in organ systems consisting of skeletal muscle, smooth muscle and cardiac muscle are also disclosed. L-Ergothioneine (also referred to as Ergothioneine or ET), Vitamin D2 (Ergocalciferol) and/or other antioxidants are disclosed for use in pharmaceutical, nutraceutical and nutritional medical food compositions for uses to stimulate production of bioactive molecules, including but not limited to glutathione, alpha synuclein, and IL-6.

The invention discloses shiitake mushroom superfine powder containing rich vitamin D2. The content of the vitamin D2 can reach the dry weight of 400mu g/100g to 20000mu g/100g and the fineness is 100 to 300 meshes. The invention further provides a processing method of the shiitake mushroom superfine powder containing the rich vitamin D2; the processing method comprises the following steps: roughly crushing dry shiitake mushroom fruit bodies, carrying out ultraviolet light wave treatment, carrying out superfine pulverization, detecting and packaging. The shiitake mushroom superfine powder containing the rich vitamin D2 has the beneficial effect that the invention provides a method for continuously and efficiently improving the content of the vitamin D2 in shiitake mushrooms; a designed modified vibration feeder is adopted so that shiitake mushroom coarse powder is uniformly subjected to irradiation treatment of ultraviolet light waves in a vibration and conveying process and the content of the vitamin D2 in the shiitake mushrooms is effectively improved; the content of the vitamin D2 of the obtained shiitake mushroom superfine powder is high and a product is fine, smooth and uniform and is a natural source of vitamin D; the shiitake mushroom superfine powder has the effects of enhancing calcium absorption, regulating calcium and phosphorus concentration of blood serum, preventing rhachitis and osteoporosis and the like; furthermore, the shiitake mushroom superfine powder can also be conveniently processed into vitamin D2 dietary supplements including powder, tablets, capsules, granules and the like.

The invention relates to a method for photochemically synthesizing vitamin D2 and D3 in a tubular reactor. The method is characterized in that the vitamin D2 and D3 are synthesized by ultraviolet light of different bands, the residence time of reaction liquid fed at different times in the tubular reactor is controlled to be the same by not dissolving with reaction liquid, not participating in reaction liquid separation and carrying ergosterol and 7-dehydrocholesterol reaction liquid and enhancing internal disturbance of the reaction liquid; the method has the advantages of continuous, stable and high efficiency of solar energy utilization, the operation is simple, and the process is controllable; the method has great prospect in the industrial production of the photochemically synthesizedvitamin D2 and D3.

The invention relates to a method for photochemosynthesis of vitamin D2, which comprises dissolving lysergol into a mixed system of nonpolar-polar solvent at the presence of nitrogen protection, charging anti-oxidant, controlling temperature of the photochemical reaction solution at 23-30 deg C, guaranteeing high concentration with mixed solvent, controlling conversion rate of the lysergol below 35%, using non-reacted lysergol as the raw material for next photochemical reaction. The process can substantially increase the concentration of the reactants.

The invention relates to the field of medicinal preparations and discloses a fat-soluble vitamin freeze-dried injection and a preparation method thereof, so as to solve the problems of clarity and stability of the fat-soluble vitamin for injection in the prior art. The freeze-dried injection contains vitamin A palmitate, vitamin D2, vitamin E, vitamin K1, ethanol, polysorbate 80, tween-20, mannitol and sodium hydroxide. The clarity and stability of the fat-soluble vitamin freeze-dried injection disclosed by the invention are greatly improved, and the medicine risk is reduced.

The invention discloses edible mushroom powder as well as a preparation method and application thereof and relates to the field of nutrient products, aiming at solving the problem that human bodies cannot effectively absorb vitamin D2 in existing mushroom powder. The preparation method of the edible mushroom powder comprises the following steps: washing and slicing mushrooms, irradiating the mushrooms with ultraviolet rays, grinding the mushrooms into powder after freeze-drying. Compared with conventional mushroom powder, the content of the vitamin D2 in the prepared mushroom powder is greatly improved and the content of the vitamin D2 can reach about 10000iu/g.

Antimicrobial cationic polymers having one or two cationic polycarbonate chains were prepared by organocatalyzed ring opening polymerization. One antimicrobial cationic polymer has a polymer chain consisting essentially of cationic carbonate repeat units linked to one or two end groups. The end groups can comprise a covalently bound form of biologically active compound such as cholesterol. Other antimicrobial cationic polymers have a random copolycarbonate chain comprising a minor mole fraction of hydrophobic repeat units bearing a covalently bound form of a vitamin E and/or vitamin D2. The cationic polymers exhibit high activity and selectivity against Gram-negative and Gram-positive microbes and fungi.

The invention relates to a preparation method to produce ergosterol with yeast in fine chemical industry, which comprises: mixing the yeast, base and sodium chloride solution for saponification, extracting by toluene, cleaning with water, condensing, refining, and drying in vacuum. This method has convenient process with low cost and provides material guarantee for vitamin D2.

The invention discloses a drug composition of compound liposoluble vitamin, which comprises the following parts: vitamin A, vitamin D2, vitamin E, vitamin K1, metal ion chelant (ethylenediamine tetra-acetic acid salt). The invention can be made into injecting emulsion to solve the problem to generate degrading product in the preparing and sterilizing course, which ensures the security of clinic drug.