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236 results about "Pathogenic organism" patented technology

The definition of a pathogenic organism is an organism capable of causing disease in its host. A human pathogen is capable of causing illness in humans. Common examples of pathogenic organisms include specific strains of bacteria like Salmonella, Listeria and E. coli, and viruses such as Cryptosporidium.

Synthetic polypeptide-containing bioapplicable material and film-forming material

InactiveUS20070207180A1Improve securityHigh bioaffinityTripeptide ingredientsImmunoglobulinsCotton effectLength wave
The present invention provides a bioapplicable material (or composition) or film-forming material (or composition), which is free from a risk of an infection by a pathogenic organism or a transmission of a causative factor, has a high safety. The material (or composition) comprises a collagen-like synthetic polypeptide having at least an amino acid sequence represented by the formula -Pro-Y-Gly- (wherein Y represents Pro or Hyp). The polypeptide may show positive Cotton effect at a wavelength in range of 220 to 230 nm and negative Cotton effect at a wavelength in range of 195 to 205 nm in a circular dichroism spectrum. At least part of the polypeptide may be capable of forming a triple helical structure. The polypeptide may be degradable with a collagenase.
Owner:PHG

Antimicrobial compositions and methods of use

The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs. In particular, decreased pathogenic organism infectivity, morbidity, and mortality is accomplished by contacting the pathogenic organism with an oil-in-water nanoemulsion comprising an oil, an organic solvent, and a surfactant dispersed in an aqueous phase.
Owner:RGT UNIV OF MICHIGAN

Methods for the diagnosis of bacterial vaginosis

The present invention relates to methods for the diagnosis of bacterial vaginosis based on an analysis of a patient sample. For example, patient test samples are analyzed for the presence or absence of one or more lactobacilli and two or more pathogenic organisms. The presence or absence of one or more lactobacilli and two or more pathogenic organisms may be detected using PCR analysis of nucleic acid segments corresponding to each target organism. The quantity of the target organisms can then be used to determine a score which is indicative of a diagnosis of bacterial vaginosis.
Owner:QUEST DIAGNOSTICS INVESTMENTS LLC

Breakpoint fusion fragment complementation system

InactiveUS20040038317A1Peptide librariesAntibody mimetics/scaffoldsHeterologousRNA-Protein Interaction
Fragment pairs of a Class A beta-lactamase (TEM-1 of E. coli) are disclosed that depend for their functional reassembly into the parent protein on the interaction of heterologous polypeptides or other molecules which have been genetically or chemically conjugated to the break-point termini of the fragment pairs. In addition, methods are provided for identifying fragment pairs that will optimally reassemble into a functional parent protein. Fragment pairs that comprise molecular interaction-dependent enzymes find use in (1) homogeneous assays and biosensors for any analyte having two or more independent binding sites, (2) tissue-localized activation of therapeutic and imaging reagents in vivo for early detection and treatment of cancer, chronic inflammation, atherosclerosis, amyloidosis, infection, transplant rejection, and other pathologies, (3 cell-based sensors for activation or inhibition of metabolic or signal transduction pathways for high-efficiency, high-throughput screening for agonists / antagonists of the target pathway, (4) high-throughput mapping of pair-wise protein-protein interactions within and between the proteomes of cells, tissues, and pathogenic organisms, (5) rapid selection of antibody fragments or other binding proteins which bind specifically to polypeptides of interest, (6) rapid antigen identification for anti-cell and anti-tissue antibodies, (7) rapid epitope identification for antibodies, (10) cell-based screens for high-throughput selection of inhibitors of any protein-protein interaction.
Owner:KALOBIOS PHARMA

Detection kit and detection method for 9 species of pathogenic organisms in marine products

The invention discloses a detection kit and a detection method for 9 species of pathogenic organisms in marine products. The kit comprises Taq DNA polymerase with a concentration of 5U / muL and a PCR reaction solution, wherein the PCR reaction solution contains 10 millimols of Tris.HCl, 50 millimols of KCl, 25 millimols of MgCl2, 2.5 millimols of dNTP and primer pairs of the 9 species of pathogenic organisms. The kit and the method can synchronously detect the 9 species of pathogenic organisms and can detect salmonella with a concentration of 11 CFU / mL, staphylococcus aurei with a concentration of 2,000 CFU / mL, monocytogenes with a concentration of 120 CFU / mL, enterohemorrhagic Escherichia coli O157:H76 with a concentration of CFU / mL, comma bacillus with a concentration of 220 CFU / mL, Vibrio parahaemolyticus with a concentration of 60 CFU / mL, Vibrio vulnficus with a concentration of 9 CFU / mL and Vibrio alginolyicus with a concentration of 230 CFU / mL. The detection method short in detection time and simple and quick in operation, and can save a large amount of labor and financial resources and meet requirements for quick detection.
Owner:曹际娟 +2

Superhigh-temperature composting method for livestock and poultry manure

The invention discloses a superhigh-temperature composting method for livestock and poultry manure. The method comprises the following steps: adjusting the water content of livestock and poultry manure to 45 to 60% by using a conditioning agent and then adding a decomposition bacterial strain for organic materials; then heating a mixed material, allowing the temperature of the mixed material to rise to 80 to 85 DEG C within 1 to 2 h and maintaining the superhigh temperature for 16 to 24 h to accomplish composting fermentation, wherein a high-pressure fan carries out aeration or stirring on the material for oxygen supply during fermentation; and after completion of fermentation, allowing the water content of an obtained composting product to fall to 20 to 30%, wherein the composting product allows the germination rate of seeds to reach 95% or above. The composting method provided by the invention can realize rapid decomposition of livestock and poultry manure, and the prepared composting product is thorough in inactivation of pathogenic organisms and low in loss of carbon and nitrogen and has substantially better fertilizer efficiency compared with traditional composting products.
Owner:JIANGSU ACADEMY OF AGRICULTURAL SCIENCES

Method for the simultaneous detection of multiple nucleic acid sequences in a sample

ActiveUS20100297630A1Shorten the timeReduce laborMicrobiological testing/measurementMultiplex ligation-dependent probe amplificationFluorescence
The invention is in the technical field of detecting nucleic acid sequences in a sample, such as the detection of pathogenic organisms in clinical samples. More specifically, the invention relates to the field of detecting an infection caused by a pathogenic organism such as a virus or a bacterium in a clinical specimen by means of amplifying and detecting specific nucleic acid sequences from said pathogenic organism. It provides a multiplex assay with the possibility to determine about 30 different target nucleic acid sequences in a single one-tube assay combined with real-time probe detection. The method employs multiplex ligation dependent Probe Amplification (MLPA) employing labelled primers in combination with labelled, probes and detection of the fluorescence.
Owner:PATHOFINDER HLDG BV

Mustard essential oil fresh preserver and application thereof in refreshing fruits and vegetables

The invention discloses a mustard essential oil fresh preserver and an application thereof in refreshing fruits and vegetables. The main active component of the mustard essential oil fresh preserver is mustard essential oil containing over 99% of allylisothiocyanate, and the mustard essential oil fresh preserver is mainly applied to a solid sustained release tablet and packaging bags made of plastic aluminum film paper. The solid sustained release tablet consists of 5%-10% of the mustard essential oil, 80%-85% of beta- cyclodextrin and 5%-10% of stearic acid. The preparation method comprises the following steps of: firstly, fully mixing and stirring the mustard essential oil and the alpha (beta)-cyclodextrin according to the proportion in a seal container, adding the stearic acid, mixing and stirring, directly packaging in the paper bags, sealing the opening in time, filling in the plastic bags, sealing by vacuumizing, or after using a tablet machine to make tablets, filling in the plastic film bags and sealing the opening, finally storing at dark places. The fresh preserver can slowly release the mustard essential oil, can be used combining with fruit and vegetable plastic film package, and is suitable for storing, conveying and refreshing various fruits and vegetables of apples, pears, grapes, jujubes, oranges, mangos, cherries, bananas, potatoes, onions, garlic and the like, thereby effectively restraining the growth of pathogenic organisms after picking up the fruits and the vegetables in the process of storing and refreshing and prolonging the refreshing time and the distance of the market circulation.
Owner:NAT ENG AN TECH RES CENT FOR PRESERVATION OF AGRI PROD TIANJIN

Vaccine delivery compositions and methods of use

The present invention provides synthetic vaccine delivery compositions based on polyester amide (PEA), polyester urethane (PEUR), and polyester urea (PEU) polymers for stimulating an immune response to a variety of pathogenic organisms and tumor cells in humans and other mammals. The vaccine delivery compositions are formulated as a liquid dispersion of polymer particles or molecules including class I or class II antigen peptides derived from organism or tumor cell proteins, which are taken up by antigen presenting cells of the mammal to induce an immune response in the mammal. Methods of inducing an immune response to the pathogenic organism or tumor cells in the invention compositions are also included.
Owner:MEDIVAS LLC
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