The invention discloses a NoSQL (not only SQL) based medical information system database implementation method. The implementation method includes the steps that A, an application program is driven to be connected to a JDBC (java database connectivity) interface through JDBC; B, the JDBC interface is called and connected to a Server module through Pyro; C, the Server module performs AST (glutamic oxalacetic transaminase) analysis upon SQL (structured query language) to obtain an AST structure tree; D, the AST structure tree is analyzed, if an association list is obtained, an Overlay operation is performed, and if an independent list is obtained, a Cache operation is performed; E, the AST structure tree is converted to form an executing script; F, the executing script is mapped to an NoSQL database through an API (application program interface). By the application of the implementation method, shortcomings in the prior art can be overcome, and rapid access with high performance, high expandability and a high-redundancy database can be realized.