The invention relates to a method for preparing
natural material inorganic
nanoparticle composite nano-
fiber through electrostatic
spinning, which comprises steps that a template is added into diluted aqueous alkali, the mixture is heated to 80-90 DEG C through an
oil bath, mixed for 1-10 hours, gradually added with
tetraethyl orthosilicate, centrifugally washed by deionized water and absolute ethyl
alcohol sequentially, and dried and reflowed in HCL-
ethanol mixed liquor to remove the template, so freeze dried mesoporous
silicon is obtained; and natural materials are dissolved in the
solvent to prepare the
natural material solution, the mesoporous
silicon is added into the
natural material solution for electrostatic
spinning, fumigating and crosslinking are carried out for 0-48 hours, so the natural material mesoporous
silicon composite nano-
fiber is obtained. The natural material inorganic
nanoparticle composite nano-
fiber which is prepared by the method has good
biocompatibility, a simple preparation method and moderate
reaction conditions, is low in experimental
raw material price, has high
drug-
loading rate, can be controlled to be released for a long term, and can be applied in the
biomedicine and tissue regeneration fields of
growth factor and
gene release of
tissue engineering,
cancer treatment and the like.