53 results about "Cell destruction" patented technology

The present invention provides systems, devices and related methods for applying electric fields for cancerous cell destruction and tissue ablation. A method can include advancing an ablation probe into a patient; deploying a guide from the delivery member along a guide tissue penetration path, deploying an electrode from the guide along an electrode tissue penetration path, and establishing current flow within the target tissue.

Method and apparatus for the ionization of living cells where an optical device (14) delivers an optical pulse having an optical field power which is modified locally by an optical field power modifying means (18) to effect ionization and destruction of living cells (16).

Disclosed are Drug Delivery Molecules (DDMs) which both facilitate functional imaging, as by PET or SPECT, and create a biological effect and methods of their use. These DDMs are variously designed to target specific receptors, then become internalized and then function biologically, as for purposes of cell destruction or therapy.

The invention discloses a combined conditioning agent for sludge deep dewatering and mud cake stabilization and an application of the combined conditioning agent, and belongs to the technical field ofsludge treatment. The combined conditioning agent comprises a cell destructing reagent, a skeleton construct, and a conditioning agent for changing a floc structure of sludge; the cell destructing reagent is preferably a hypochlorite or chlorine gas, hypochlorous acid and derivatives of the hypochlorous acid produced in the conditioning process can penetrate an extracellular polymer of the sludgeand cell walls and oxidize intracellular matter, so that cells in the sludge are destructed, and harmful bacteria such as parasitic eggs and pathogens in the sludge are inactivated; coagulation and / or flocculation of the sludge by a coagulant and / or flocculant can further release extracellular and intracellular bound water of the sludge; and as an inert substance, the skeleton construct can maintain a water outlet channel of water in the sludge pressure filtration process, so that the sludge intracellular water released by the cell destruction can be quickly removed. The pretreatment method for the sludge provided by the invention can simultaneously achieve the dual purposes of deep dewatering of the sludge and inactivation of the harmful bacteria in the sludge.

Disclosed are Drug Delivery Molecules (DDMs) which both facilitate functional imaging, as by PET, MRI or SPECT, and create a biological effect and methods of their use. These DDMs which are variously designed to target specific receptors, internalized and then function biologically, as for purposes of cell destruction or therapy.

Disclosed is a pO157 plasmid-specified polypeptide found in E. coli EDL933 and other E. coli that binds to and cleaves C1-esterase inhibitor, and antibodies specific for the polypeptide. Also disclosed are methods employing the polypeptide for diagnosing enterohemorrhagic E. coli infection, identifying potential inhibitors of its activity, and reducing viscosity of material containing glycosylated polypeptides.

The present invention relates to pyrimidinones and pyridones and derivatives thereof, and pharmaceutically acceptable salts thereof. Also included is a method of treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic β cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs. host reaction, Alzheimer's disease, stroke, myocardial infarction, ischemia reperfusion injury, atherosclerosis, brain trauma, multiple sclerosis, cerebral malaria, sepsis, septic shock, toxic shock syndrome, fever, myalgias due to HIV-1, HIV-2, HIV-3, cytomegalovirus (CMV), influenza, adenovirus, the herpes viruses or herpes zoster infection in a mammal comprising administering an effective amount a compound as described above.

The high-efficiency production process of Wuyi rock tea handmade high-end Laocong group tea or tea cake is characterized in that the process steps include: (1) withering, (2) greening, (3) cutting stems, (4) frying greens, (4) Kneading, (5) Pressing (6) Baking; the withering method of (1) the withering process is: withering the old Cong tea green in the sun, or evenly spreading the old Cong tea green on the withering tank and heating and withering The (2) greening process is completed on the withering tank, and the fermentation and standing process is carried out according to the conventional process of Wuyi rock tea, which achieves the destruction of some cells of the green leaves of Laocong tea, thereby promoting the method of enzymatic oxidation: The tea greens are evenly spread on the withering trough. During the greening process, the old cong tea greens on the withering trough are horizontally pressed with a needle board by hand to form evenly distributed tiny needle holes on the leaves of the old cong tea greens, so that the old cong tea greens Part of the cells of the leaves are destroyed, thereby promoting enzymatic oxidation; the structure of the acupuncture board is: the stainless steel needles with sharp heads are arranged in an orderly manner on the supporting board, and a handle is installed on the back of the supporting board to form the acupuncture board. The (3) stem-cutting process is manually cut off the green tea stems of the old congcha green tea that has completed the greening process.

An apparatus for disrupting cells or viruses comprises a container having a chamber for holding the cells or viruses. The container includes at least one flexible wall defining the chamber. The apparatus also includes a transducer for impacting an external surface of the flexible wall to generate pressure waves in the chamber. The apparatus also includes a pressure source for increasing the pressure in the chamber. The pressurization of the chamber ensures effective coupling between the transducer and the flexible wall. The apparatus may also include beads in the chamber for rupturing the cells or viruses.

There is provided a method for preventing disruption and aggregation of stem cells. In addition, there is provided a stem cell composition for intravascular administration, in which stem cells are suspended in a solution containing aspirin. Further, there is provided a composition for preventing disruption or aggregation of stem cells, in which stem cells are suspended in a solution containing aspirin.According to the present invention, disruption and aggregation of cells may be prevented during transport or storage, such that the administered stem cells may stably reach the target tissue and exhibit the activity thereof in a more efficient manner, thereby remarkably increasing the effect of cell therapy using stem cells.

The present invention discloses gold eucommia ulmoides black tea and a preparation method thereof. The method comprises the following steps: (1) withering is conducted: 20-30 parts of young leaves ofeucommia ulmoides and 60-70 parts of young leaves of chimonanthus salicifolius are mixed, and the mixture is withered; (2) enzyme digestion is conducted: 5-10% of enzymatic hydrolysate is added into the withered leaves to be enzyme-digested for 1-3 hours; (3) kneading is conducted: cell destruction rate is 90% or more and tea juice is overflowing without dripping; (4) fermentation is conducted: the kneaded tea leaves are subjected to an oxygen fermentation to enable green grass smell to disappear and form unique aroma of the gold eucommia ulmoides black tea, and leaf color is dark red; and (5)drying is conducted: the fermented tea leaves are sent into a dryer to be dried to a water content of 5-6%. The obtained gold eucommia ulmoides black tea is dark red, full in shape, beautiful in appearance, and highly penetrating in aroma. Brewed tea soup is mellow in mouthfeel, rich in aroma, and free of any astringent and bitter taste, and has unique flavor of the gold eucommia ulmoides black tea. Besides, the product has both relatively good auxiliary effects on hypertension and hyperlipidemia.

The present invention relates to pyrimidinones and pyridones and derivatives thereof, and pharmaceutically acceptable salts thereof. Also included is a method of treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic β cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs. host reaction, Alzheimer's disease, stroke, myocardial infarction, ischemia reperfusion injury, atherosclerosis, brain trauma, multiple sclerosis, cerebral malaria, sepsis, septic shock, toxic shock syndrome, fever, myalgias due to HIV-1, HIV-2, HIV-3, cytomegalovirus (CMV), influenza, adenovirus, the herpes viruses or herpes zoster infection in a mammal comprising administering an effective amount a compound as described above.