357results about How to "Shorten analysis time" patented technology

Systems and methods for analyzing genetic sequence data involve: (a) obtaining, by a computer system, genetic sequencing data pertaining to a subject; (b) splitting the genetic sequencing data into a plurality of segments; (c) processing the genetic sequencing data such that intra-segment reads, read pairs with both mates mapped to the same data set, are saved to a respective plurality of individual binary alignment map (BAM) files corresponding to that respective segment; (d) processing the genetic sequencing data such that inter-segment reads, read pairs with both mates mapped to different segments, are saved into at least a second BAM file; and (e) processing at least the first plurality of BAM files along parallel processing paths. The plurality of segments may correspond to any given number of genomic subregions and may be selected based upon the number of processing cores used in the parallel processing.

Multiply charged ions are trapped and accumulated in a spatially limited region before being injected into an ion trap mass spectrometer such as a Fourier transform ion cyclotron resonance mass spectrometer (FTICR MS). In the ion trap electron capture dissociation (ECD) and vibrational excitation dissociation are sequentially applied on ions of the same ion ensemble. The first dissociation process does not fragment all primary ions. Following the detection of the dissociation products, the primary ions that remain undissociated undergo the vibrational excitation and again, a part of them dissociate, and the fragments are detected. Thus, the same ion ensemble is used for two fragmentation processes. During these processes, further ions generated in the external ion source are accumulated in the spatially limited region for subsequent analyses.

A method for extracting proteins from heterogeneous fluids by precipitation using microfluidics. The method uses an automated protocol for precipitation of proteins onto surfaces, rinsing the precipitates to remove impurities, and resolubilization in buffer for further analysis. The method is compatible with proteins representing a range of different physicochemical properties, as well as with complex mixtures such as fetal bovine serum and cell lysate. In all cases, the quantitative performance (measured using a fluorescent assay for % recovery) was comparable to that of conventional techniques, which are manual and require more time.

A microfabricated mass-sensitive chemical preconcentrator actively measures the mass of a sample on an acoustic microbalance during the collection process. The microbalance comprises a chemically sensitive interface for collecting the sample thereon and an acoustic-based physical transducer that provides an electrical output that is proportional to the mass of the collected sample. The acoustic microbalance preferably comprises a pivot plate resonator. A resistive heating element can be disposed on the chemically sensitive interface to rapidly heat and release the collected sample for further analysis. Therefore, the mass-sensitive chemical preconcentrator can optimize the sample collection time prior to release to enable the rapid and accurate analysis of analytes by a microanalytical system.

The embodiment of the invention provides a message processing method and a device and a system thereof. The method comprises the following steps of: receiving a first domain name resolving request message sent by a host computer, wherein the first domain name resolving request message carries a domain name required to be resolved by the host computer; determining a first DNS (Domain Name Server) from a domain name system DNS priority list, wherein the first DNS belongs to a DNS server set with a highest priority in the DNS server priority list; and sending a second domain name resolving request message to the first DNS according to the first domain name resolving request message, wherein the second domain name resolving request message carries a domain name required to be resolved by the host computer. According to the message processing method and the device and the system, provided by the embodiment of the invention, a DNS server is selected from the DNS server set with the highest priority in the DNS server priority list, so that the domain name resolving time can be shortened, and domain name resolving failures are avoided.

The present invention has an analyzing unit including an image detection device for producing a plurality of images of a workpiece, a storage for storing detected images produced by the image detection device, and a display having a screen with a first area for displaying a plurality of detected images stored in the storage and a plurality of second areas for classifying the detected images according to features of the detected images, whereby the plurality of detected images are moved on the screen from the first area to selected second areas to classify the plurality of detected images in the second areas.

A method for mass spectral analysis of a sample containing a plurality of biomolecule species comprises: (a) mass analyzing a plurality of first-generation ion species generated from a sample portion; (b) automatically recognizing, for each of at least one biomolecule species, a respective subset of m / z ratios corresponding to respective first-generation ion species generated from the each biomolecule species; (c) selecting, from each recognized subset, a single representative m / z ratio; (d) isolating a sub-population of ions having each representative m / z ratio from ions having other m / z ratios; and (e) fragmenting each isolated sub-population of ions so as to generate second-generation ion species.

A method for synthesising mesoporous silica microparticles comprising the steps of: —preparing a sol from an ammonium catalysed hydrolysis and condensation reaction of a pre-sol solution comprising a silica precursor and a structure directing agent dissolved in a mixed solvent system comprising an alcohol and water to produce mesoporous particles of silica with an average diameter of up to about 50 μm; hydrothermally treating the particles to increase the pore size; treating the particles to remove residual structure directing agent; and further increasing the pore size using controlled dissolution.

The invention encompasses molecular beacon (MB) probes for monitoring the presence of human breast cancer biomarkers and for the analysis of breast cancer metastasis. The molecular beacon is an oligonucleotide probe which sensitively and specifically identifies biomarker mRNA in samples, in the presence of serum, in minimal time using fluorescence detection. The molecular beacons may be comprised in kits for the detection / quantitation of cancer biomarkers in clinical samples. The invention provides improvements in simplicity, accuracy, and speed over current methods, which could allow for improved patient treatment and prognoses.

A new generation polarimetry apparatus and methodology is disclosed, which involve passing polarized light through a sample including a chiral analyte, where the analyte is under the influence of a periodically varying magnetic field. The apparatus also utilizes optical heterodyne detection and lock-in detection at higher order harmonics of the magnetic field modulation frequency to improve sensitivity and detection limits of optical properties of chiral analytes.

Systems and methods for using electronic portal imaging devices (EPIDs) as absolute radiation beam measuring devices and as radiation beam alignment devices without implementation of elaborate and complex calibration procedures.

Suppressor and anti-suppressor additives in an acid copper sulfate plating bath are analyzed by the cyclic voltammetric stripping (CVS) method without cleaning or rinsing the cell between the two analyses. The suppressor analysis is performed first and the suppressor concentration in the resulting measurement solution is adjusted to a predetermined value corresponding to full suppression. This fully-suppressed solution is then used as the background electrolyte for the anti-suppressor analysis. This integrated analysis approach provides results comparable to those obtained with cell cleaning and rinsing between the analyses but significantly reduces the analysis time, consumption of expensive chemicals, and quantity of hazardous waste generated.

Provides an apparatus for detecting variants of malicious code based on neural network learning, a method therefor and a computer readable recording medium storing a program for performing the method. According to the present invention, one-dimensional binary data is converted into two-dimensional data without separate extraction of features, and deep learning is performed through a neural network having a nonlinear multilayered structure, such that the features of the malicious code and variants thereof may be extracted by performing the deep learning. Therefore, since no separate feature extraction or artificial effort by an expert is required, an analysis time is reduced, and variants of malicious code that cannot be captured by existing malicious code classification tools may be detected by performing the deep learning.

The invention relates to the field of the quality control on traditional Chinese medicine, specifically to a quality control method for erigeron breviscapus(Vant.) hand-mazz. The method comprises a fingerprint detection method and a multiple-indicative content detection method for erigeron breviscapus (Vant.) hand-mazz, wherein the fingerprint detection method employs UPLC detection method, through which 24 characteristic peaks are found and 8 characteristic peaks are ascribed. By using content detection method for erigeron breviscapus(Vant.) hand-mazz., the UPLC-PDA method, contents of following constituents are determined: erigeroside, chlorogenic acid, breviscpini glycoside, Scutellarin, 3,4-0-dicaffeoylquinic acid, 3,5-0-dicaffeoylquinic acid and 4,5-0-dicaffeoylquinic acid. Compared with the prior art, the fingerprint detection method and the multiple-indicative content detection method for erigeron breviscapus (Vant.) hand-mazz are improved in the invention, so that the quality of erigeron breviscapus (Vant.) hand-mazz. can be controlled in a convenient, rapid and accurate manner, thereby ensuring the quality of erigeron breviscapus (Vant.) hand-mazz. stable, uniform and controllable.

The invention relates to an ethylene oxide preheating, sterilization and resolution integrated cabinet and a sterilizing method. The integrated cabinet comprises a cabinet body, wherein a sealing door is arranged on the front part of the cabinet body; a cavity in the cabinet body is connected with a vacuum pump through a vacuumizing pipeline; the cavity in the cabinet body is connected with a humidifying device through a humidifying pipeline; the cavity in the cabinet body is connected with wet and hot air making devices through wet and hot air delivery pipelines; a heating water jacket is arranged outside the cabinet body; a circulating air pipeline is arranged on the outer side of the cabinet body; a fan is connected in series to the circulating air pipeline; an air inlet of the circulating air pipeline is arranged on one side in the cabinet body; an air outlet of the circulating air pipeline is arranged on the other side in the cabinet body; and the cabinet body is connected with an ethylene oxide container through a pipeline provided with a valve. The ethylene oxide preheating, sterilization and resolution integrated cabinet has the advantages of high operating efficiency, few matched facilities, low fault rate, short construction period, low daily using cost and low energy loss, and can reduce pollution to human body and environment and improve the comprehensive benefit by over 40 percent.

This device comprises a pulsed laser source (6), means (8, 10, 12) for focusing light from this source onto an object to be analysed (2) to produce plasma on the surface of the object, means (16, 18) of analyzing a plasma radiation spectrum, means (20) of determining the elementary composition of the object from this analysis, and possibly means (4) for displacing the object. The invention is particularly applicable to test radioactive materials.