The invention discloses hollow glass based on a single-component solventless hot melt adhesive, the hollow glass comprises inner layer glass, outer layer glass, spacing bars, membrane material interlayers and edge sealing metal membranes, the spacing bars are packaged between the peripheries of the inner layer glass and the outer layer glass through the hot melt adhesive, and the peripheries of the membrane material interlayers are respectively adhered to the inner sides of the corresponding spacing bars through the hot melt adhesive. The membrane material interlayers are used for separating a space between the inner-layer glass and the outer-layer glass, and the edge sealing metal membrane is adhered to the spacing bar through a hot melt adhesive and wraps the outer side surfaces of the inner-layer glass and the outer-layer glass on the two sides; the hot melt adhesive is prepared from the following raw materials in parts by weight: 30 to 50 parts of isocyanate, 60 to 90 parts of polyester polyol, 10 to 30 parts of polyether polyol, 0.1 to 5 parts of a chain extender, 0.1 to 3 parts of a hydrolysis-resistant agent, 0.1 to 2 parts of an adhesion promoter, 0.1 to 2 parts of a latent curing agent, 0.1 to 0.5 part of a catalyst and 0.1 to 0.3 part of an antioxidant. Through cooperation of the optimized structure and the hot melt adhesive, the heat insulation, sound insulation and barrier properties of the hollow glass are improved, and the hollow glass is light in weight.