The invention discloses a method, system and device for realizing fully automatic vending, which relate to the technical fields of automatic control, intelligent identification, intelligent monitoring, etc.; its fully automatic vending system includes a combination of vending units and a combination of main control units. The merchandise unit combination is divided into the left merchandise unit combination and the right merchandise unit combination. RFID read-write equipment and micro cameras are installed in the merchandise unit. The main control unit includes frame, rear door, display, display frame, top cover, Composed of strips, the sales unit combination includes A-type sales window unit, B-type sales window unit, side door, rear door, top cover, LED dynamic advertising area, front combined frame, rear combined frame, and reinforced horizontal bars. The beneficial effects of the present invention are: it is a completely open vending system, which is basically consistent with the traditional supermarket shopping mode, without labor costs, without renting a storefront, and provides a method for the survival of physical stores; at the same time, this method also provides Online shopping provides an experience place and promotes the rapid development of the Internet economy.