Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

49results about How to "Guaranteed long-term security" patented technology

Small molecule antagonists of BCL-2 family proteins

The present invention relates to naturally occurring and chemically synthesized small molecule antagonists of Bcl-2 family proteins. In particular, the present invention provides gossypol compounds (e.g., isomers, enantiomers, racemic compounds, metabolites, derivatives, pharmaceutically acceptable salts, in combination with acids or bases, and the like) and methods of using these compounds as antagonists of the anti-apoptotic effects of Bcl-2 family member proteins (e.g., Bcl-2, Bcl-XL, and the like). The present invention also provides compositions comprising gossypol compounds and optionally one or more additional therapeutic agents (e.g., anticancer / chemotherapeutic agents). The present invention also provides methods for treating diseases and pathologies (e.g., neoplastic diseases) comprising administering a composition comprising gossypol compounds and optionally one or more additional therapeutic agents (e.g., anticancer / chemotherapeutic agents) and / or techniques (e.g., radiation therapies, surgical interventions, and the like) to a subject or in vitro cells, tissues, and organs.
Owner:RGT UNIV OF MICHIGAN +1

Diversified engineered safety system for nuclear reactor

The invention aims at providing a diversified engineered safety system for a nuclear reactor. The diversified engineered safety system comprises a loop passive residual heat removal subsystem, a secondary-side passive residual heat removal subsystem of a steam generator fed with water by gravity, a total-pressure active residual heat removal subsystem, a low-pressure passive safety injection subsystem and a water-flooding and air-cooling combined passive containment cooling subsystem. All the subsystems can independently run or can be matched with one other, and parallel and redundant complete residual heat removal channels with diversified principles are built between a reactor core and an ultimate heat sink, so that a main system and the reactor core of the reactor can be quickly and efficiently cooled and the reactor can quickly enter a safety state in the initial stage of an accident. Even if one subsystem has a fault, other subsystems can still complete a complete and effective residual heat removal function for guaranteeing that the reactor is effectively cooled.
Owner:SHANGHAI NUCLEAR ENG RES & DESIGN INST CO LTD +1

Shield tunnel pipe piece designing method taking double-liquid synchronous grouting layer performance degradation into consideration

The invention discloses a shield tunnel pipe piece designing method taking double-liquid synchronous grouting layer performance degradation into consideration. The method comprises a first step of determining different distributing patterns of gel calcium silicate in cement-water glass double liquid based on careful observation and analysis, a second step of calculating occurrence frequency, occupied area proportion and structural effect influence coefficient of the gel calcium silicate in different distributing patterns, a third step of carrying out discount calculation on the mechanical property of the cement-water glass double liquid which is degraded by the gel calcium silicate according to a calculated result, and a fourth step of calculating the internal force and the deformation of a shield tunnel pipe piece lining structure by the adoption of the modified routine method. By means of the method, an accurate and effective evaluation can be carried out on the long-term mechanical property of the cement-water glass double liquid which is degraded by the gel calcium silicate which is a reaction product of the double liquid, then the evaluation is carried out on the long-term safety performance of a tunnel structure and other building structures using the cement-water glass double liquid, the method is used for designing shield tunnel pipe pieces, and the result is realer and more reliable.
Owner:SOUTHWEST JIAOTONG UNIV +1

Concrete for dams and preparation method thereof

ActiveCN103232202AIncreased durabilitySolve technical problems prone to aggregate reactionWater reducerMagnesium chlorate
The invention discloses a concrete for dams. Every cubic meter of concrete comprises the following raw materials: 700-750kg of sand, 1000-1050kg of gravel, 90-110kg of water, 300-350kg of cement, 100-120kg of fly ash, 6.0-6.5kg of water reducing agent, 65-95kg of air entraining agent, 50-70kg of magnesium chloride solution, 3-5kg of additive and 30-50g of composite rare earth. The invention also discloses a preparation method of the concrete. By adding proper admixtures on the premise of not obviously increasing the cement content, the invention obviously enhances the primary indexes of the concrete, greatly lowers the initial hydration heat of cement, avoids temperature cracking, can be widely used for dam concreting or other mass concreting under different climatic conditions, and has important meanings for enhancing the engineering quality and ensuring the long-term safety of engineering.
Owner:CHINA YANGTZE POWER +1

Pipe type underground water drainage blind ditch and construction technology and application thereof

ActiveCN103643689AExcellent and stable drainage capacityExtend working lifeGround-workSoil drainageEngineeringGabion
The invention discloses a pipe type underground water drainage blind ditch. The structure is optimized and improved on the basis of an existing pipe type underground water drainage blind ditch in a landfill. A left gabion pillar and a right gabion pillar are symmetrically arranged on the two sides of a pipe culvert, a flexible unloading body is arranged between the left gabion pillar and the right gabion pillar and arranged over the pipe culvert, the top face of the flexible unloading body is flush with the top face of the left gabion pillar and the top face of the right gabion pillar, and a load transmission layer covers the top faces of the left gabion pillar, the right gabion pillar and the flexible unloading body. The blind ditch has the advantage that the pipe culvert cannot be broken under the action of the high filling load on the upper portion of the blind ditch, the blind ditch is suitable for being arranged under the landfill, especially a high landfill, and is used as an underground water drainage structure for the landfill, and it is ensured that the underground water stably drains out of the landfill.
Owner:SHANGHAI SHEN YUAN GEOTECHN +2

Safety Helmet Liner Impact Reducing Technology

An article of headwear includes an inner liner 20, a corrugated shell 24, and an outer shell 26. An impact to headwear causes the corrugated shell to elastically deform, with the shell then returning to its original shape. An arrangement of the corrugations allows ease of manufacturing on a vacuum form or injection mold.
Owner:DVORAK PAUL WILLIAM

Extending-bulging type glue fixing nail and use method

The invention relates to an expansion adhesive fastening nail and a use method thereof, wherein the expansion adhesive fastening nail consists of a big-end tube expansion nail, an expansion sleeve, a hanging piece head and adhesive; the big-end tube expansion nail (1) is matched with the expansion sleeve (9) and is fixed with a wall body; an expansion plate (12) expands to exceed the nail head of the big-end tube expansion nail (1) and splits into the shape of petals; the nail head of the big-end tube expansion nail (1) is clamped at a petaloid bottom to increase pulling resistant and shear resistant; therefore, the nail is particularly suitable to install various equipment and veneers on floppier wall bodies such as an autoclaved aerated concrete wall body, thereby ensuring the longtime safety and steadiness of a project; moreover, the member saves raw material and reduces cost along with a reasonable and convenient use method. Obviously, the nail and the method have high use value and enormous social benefits and economic benefits.
Owner:郭祥山

Large-stroke combined damper utilizing post-peak performance of materials

The invention provides a large-stroke combined damper utilizing the post-peak performance of materials. The large-stroke combined damper comprises a circumferential damper and a radial damper, and the circumferential damper and the radial damper are arrayed around the inner side of a tunnel to form a ring; the circumferential damper is fixedly installed in the tunnel, and the deformation direction is in the circumferential direction of the tunnel; the radial damper is fixedly installed in the tunnel, and the deformation direction is in the radial direction of the tunnel; the circumferential damper is positioned on the inner side of the radial damper. Supporting and deformation can not only be provided in the circumferential direction of the tunnel, but also can be provided in the radial direction of the tunnel, stress of the tunnel is effectively released, so that the tunnel structure is more stable and reliable.
Owner:仇文革

Steel wire fixing structure for end of steel wire mesh framework polyethylene composite pipe, and steel wire mesh framework polyethylene composite pipe connecting structure and method

The invention relates to the technical field of pipe connection, in particular to a steel wire fixing structure for the end of a steel wire mesh framework polyethylene composite pipe, and a steel wire mesh framework polyethylene composite pipe connecting structure and method. The steel wire fixing structure for the end of the steel wire mesh framework polyethylene composite pipe is structurally characterized in that an outer steel ring is embedded in the end of the steel wire mesh framework polyethylene composite pipe, a circle of protrusion is arranged on the edge of the outer steel ring, and the protrusion is located on the side away from the edge of the steel wire mesh framework polyethylene composite pipe; and the end of the steel wire mesh framework polyethylene composite pipe is folded towards the outer steel ring, the folded position extends to the protrusion, and an inner steel ring is embedded in the outer part of the folded steel wire mesh framework polyethylene composite pipe. The problems that in the prior art, steel wires at the end of steel wire mesh framework polyethylene composite pipes are prone to scattering, and in the connecting process, a sealing gasket and a flange are prone to leaking and falling off; and the tightening degrees of bolts on the flange need to be completely consistent, so that the operation is very difficult are solved.
Owner:SHANDONG DONGHONG PIPE IND

Device and method for testing soil structure under the action of dynamic change of underground confined water level

The invention discloses a device and a method for testing soil structure characteristics under action of dynamic change of underground pressure water head. The testing system comprises a calibration tank, a loading device, a confined water control system and a measurement system and also comprises a corresponding data analysis method, wherein a cohesive soil layer and a sandy soil layer are arranged in the calibration tank in a layered mode so as to simulate to form an underground water-bearing structure; the confined water control system is formed by connecting a water tank which can be freely controlled to lift and a water inlet and outlet pipe; the measurement system comprises an electrical resistivity testing module, a soil deformation testing module, a water head pressure measuring tube, a micro pore pressure gage and a micro static penetrometer, and the electrical resistivity testing module consists of testing electrodes in the circular and vertical directions. The calibration tank serves as a bearing device and is matched with other several systems, so that the change of soil structure characteristics under complex conditions of dynamic change of the underground pressure water head can be dynamically tested, the influence on the soil characteristics is further analyzed, and basic data is provided for evaluating the structural behavior and health state of underground construction under complex conditions.
Owner:SOUTHEAST UNIV

Distributed optical fiber temperature measurement system suitable for tunnel temperature measurement and temperature measurement method thereof

The invention provides a distributed optical fiber temperature measurement system suitable for tunnel temperature measurement and a temperature measurement method thereof. The system comprises the distributed optical fiber temperature measurement system, a sensing optical fiber and an upper computer. The distributed optical fiber temperature measurement system comprises a control panel, a pulse semiconductor laser PLD, a wavelength division multiplexing component, a calibration optical fiber, a photoelectric detector APD, a signal amplifier and an acquisition board. The sensing optical fiber comprises an optical fiber jumper (1) and an armored multi-mode optical fiber (2). The advantages are that the distributed optical fiber temperature measurement system is introduced in tunnel detection in engineering so that the disadvantages of discontinuous, inaccurate and unreliable conventional measurement can be overcome. The performed measurement is continuous measurement along an optical fiber path so that the continuous monitoring data of the tunnel can be acquired, the means of tunnel detection can be improved by the technology, a large number of new parameters related to diseases can be provided and the long-term safety of the tunnel can be powerfully guaranteed.
Owner:YUNNAN AEROSPACE ENG GEOPHYSICAL SURVEY INSPECTION

Dithiocarbamate functionalized dendrimer with alkylenediamine core as soil heavy metal immobilization amendment and preparation method thereof

A dithiocarbamate functionalized dendrimer with an alkylenediamine core, a dithiocarbamate pendant functional group and a dithiocarbamate end functional group, as a soil heavy metal immobilization amendment, and a preparation method thereof are provided. The dithiocarbamate functionalized dendrimer has a chemical formula of (CH2)a{N[CH2CH2COOCH2C(C2H5)(CH2OCOCH2CH2N(CSSM)CH2(CH2)bCH2N(CSS M)2)2]2}2, wherein a is a positive integer larger than 2; b is a positive integer at a range of 0-4; and M is Na+, NH4+ or K+. The dithiocarbamate functionalized dendrimer with the alkylenediamine core is used for an in-suit immobilization remediation for soil contaminated by heavy metals, and has advantages of a small dosage, high efficiency, safety and rapidness. The dendrimer is able to effectively immobilize exchangeable and carbonated bound forms of the heavy metals, in such a manner that the immobilized heavy metals are able to resist an influence from natural environment for a long term, such as an acid rain.
Owner:TONGJI UNIV

Alcoholic beverage for preventing cervical spondylosis, lumbar disc herniation and scapulohumeral periarthritis

The invention discloses an alcoholic beverage for preventing cervical spondylosis, lumbar disc herniation and scapulohumeral periarthritis, and belongs to the technical field of beverages. The formula of the alcoholic beverage comprises the following components, by weight, 2-10 parts of mulberry, 2-10 parts of wolfberry fruit, 3-10 parts of Polygonatum sibiricum, 2-10 parts of dahurian angelica root, 2-10 parts of Peach Seed, 1-5 parts of safflower, 2-10 parts of Radix Puerariae, 2-10 parts of sophora japonica, 30-60 parts of distilled water, 5-10 parts of honey, and 100-200 parts of a white wine. The alcoholic beverage is compounded according to the traditional Chinese medicinal theoretic composition, has the efficacies of liver and kidney nourishing, blood circulation invigorating, vein relaxing and pain relieving, treats alcohol as a carrier, makes nutrients reach all corners of a body as possible by means of the diffusion performance of the wine, and especially reach positions comprising cervical vertebra, lumbar vertebra and shoulder joints which cannot be reached by routine aqueous solutions, and has the advantages of taking convenience, substantial improvement of the sleep condition of a patient, and benefiting for the physical and mental health of the patient.
Owner:XUZHOU GUPENG LIQUOR IND

Water level amplitude area panel maintenance intelligent system and control and maintenance method

The invention relates to a water level amplitude area panel maintenance intelligent system and a control and maintenance method. The water level amplitude area panel maintenance intelligent system includes a drainage floral tube fixedly arranged on a concrete panel, the drainage floral tube is in communication with the bottom of a water box through a first communication tube and an electrically operated valve, and the water box is connected with a water supply device; a temperature acquisition instrument for monitoring environmental temperature is installed on the concrete panel and on the middle part of the top of the drainage floral tube; the concrete panel is mounted with an evaporation quantity detection device for monitoring the evaporation amount of water in a dam body; and the temperature acquisition instrument, the water supply device and the evaporation quantity detection device are connected with a hardware control device through a signal line and automatically control the drainage operation of the drainage floral tube. The water level amplitude area panel maintenance intelligent system aims to solve the problem that the existing built concrete panel dam is prone to beingcracked due to the large temperature difference of climate and the improper maintenance of the water level amplitude area panel during the operation period.
Owner:POWERCHINA CHENGDU ENG

Extension arm type drainage slide-resistant pile and structural calculation method thereof

An extension arm type drainage slide-resistant pile comprises a main pile column, and an extension arm and a drainage structure are arranged on the main pile column. The extension arms are arranged on the main pile column and located in front of and behind the main pile column, and the extension arms in front of and behind the main pile column achieve conversion from a sliding-blocking mode to a sliding-self-stabilizing-blocking mode between the sliding mass and the anti-sliding pile through development and utilization of the sliding mass. The drainage structure is arranged on the outer side of the main pile column and is formed by splicing pile core outer molds; a water inlet hole is formed in the outer wall of the drainage structure, a water storage cavity and a water vapor overflow pipe are arranged in the drainage structure, wherein the water vapor overflow pipe is communicated with the outside. According to the extension arm type drainage slide-resistant pile and the structural calculation method thereof, the positive effect of a landslide body can be developed and utilized, and the effect of the anti-slide pile is improved; water can be drained to overcome the stagnant water effect of the slide-resistant pile.
Owner:CHINA THREE GORGES UNIV +1

Protective layer for protecting lithium metal negative electrode for lithium secondary battery, production method thereof, and lithium secondary battery including the same

Disclosed is a protective layer to protect a lithium metal negative electrode for a lithium secondary battery, in which the protective layer may inhibit formation of lithium dendrite and improve thermal / chemical stability, and conductivity of lithium ions. Further, disclosed are a production method of the protective layer, and a lithium secondary battery including the protectively layer. The protective layer contains a poly(arylene ether sulfone)-poly(ethylene glycol) graft copolymer represented by a following Chemical Formula 1:where, in the Chemical Formula 1, n is an integer of 60 to 80, and m is an integer of 40 to 45.
Owner:RES & BUSINESS FOUNDATION SUNGKYUNKWAN UNIV

Method for constructing thermal insulation layer controlled by equal height insulation batten of step type

The invention relates to walls, roof surfaces, and stilt floor slabs of industrial and civil buildings, in particular to a construction method for control insulation layers of step type equal height insulation laths. The invention is characterized in that the step type equal height insulation laths are connected on a base course wall through bonding agent to form reference control, then a polyurethane hard foam insulation layer is spray coated and a slurry material insulation layer is applied between two step type equal height insulation laths, so as to realize the effective control of the layer thickness and the overall thickness of the insulation layers. The polyurethane hard foam insulation layer is spray coated according to the height of a first step H1 of the step type equal height insulation laths, and the slurry material insulation layer is applied according to the height of a second step H2 of the step type equal height insulation laths. The width of the step type equal height insulation laths is 70 to 120 mm. The invention has the advantages that the application of the step type equal height insulation laths realizes the effective control to the thickness of the two insulation materials in the construction process; after the polyurethane hard foam insulation layer is spray coated, the surface is not required to be finished, thereby the labor intensity is reduced, the working time is saved and the environment pollution caused by construction waste generated by finishing the surface is reduced; the insulation layers have good insulation integrity and consistent thermal performance, edge joints and a hot bridge effect of large thickness insulation layers of EPS, etc. can be avoided, and the high efficiency and the energy conservation can be realized.
Owner:康玉范

Primary support structure and method for controlling surrounding rock deformation through preexpansive force

The invention relates to a primary support structure and method for controlling surrounding rock deformation through preexpansive force. The structure comprises top profile steel, the two ends of the top profile steel are connected with side profile steel correspondingly, and the top profile steel and the side profile steel are combined to form an arched steel frame; the top profile steel is connected with the side profile steel through a sleeve, a notch is formed in the side wall of the sleeve and used for taking and placing a jack out of and into an inner cavity of the sleeve, and the jack can adjust the distance between the top profile steel and the side profile steel to apply prestress to surrounding rock; and a supporting plate can be placed in the inner cavity of the sleeve through the notch, the supporting plate can fill the space after the jack is taken out, and the supporting plate can be fixed to the sleeve, the side profile steel and the top profile steel so as to keep the prestress of the arched frame to surrounding rock. According to the structure and method, the prestress can be applied to the tunnel surrounding rock during primary supporting, so that wriggling of the tunnel after primary supporting is reduced.
Owner:JINAN MUNICIPAL ENG DESIGN & RES INSITITUTE GRP

Signature and signature verification method and device and storage medium

The invention discloses a signature and signature verification method and device and a storage medium, and the method comprises the steps: a signature party and a key distribution party respectively cut a basic key into a plurality of signature key components, and pre-store the signature key components as key component sequences; when the signature party performs signature, calculating a digital signature for the to-be-signed message based on the key component sequence, generating a signature result based on the digital signature and the identification information of the signature party, and sending the to-be-signed message and the signature result to a signature verification party; and the signature verification party calculates the message digest of the message to be signed and entrusts the trusted party to complete signature verification operation according to the message digest, the signature result and a key component sequence pre-stored by the key distributor associated with the signature party. According to the technical scheme provided by the invention, the technical problem that quantum threats are faced when a public key and a private key are used for signature and signature verification in the prior art can be solved.
Owner:南京易科腾信息技术有限公司

Electrochemical device and electric equipment

The invention discloses an electrochemical device and electric equipment. The electrochemical device comprises an electrode assembly, the electrode assembly comprises a first pole piece, a first isolation layer, a second pole piece and a second isolation layer, the first isolation layer is located between the first pole piece and the second pole piece, and the second pole piece is located between the first isolation layer and the second isolation layer; in the first direction, the first isolation layer comprises a first extension part exceeding the second pole piece, and the second isolation layer comprises a second extension part exceeding the second pole piece; the first extending part comprises a first bonding area, the second extending part comprises a second bonding area, the bonding force between the first bonding area and the second bonding area is F1, and F1 is larger than or equal to 5N / m. According to the electrochemical device, the isolating layers on the two sides of the pole pieces are bonded, the isolating layers are prevented from shrinking at high temperature, or the isolating layers are prevented from turning inwards at the edge due to impact of electrolyte during falling, and isolation between the positive pole piece and the negative pole piece is ensured to prevent short circuit.
Owner:NINGDE AMPEREX TECH

Alcoholic beverage for preventing cervical spondylosis, lumbar disc herniation and scapulohumeral periarthritis

The invention discloses an alcoholic beverage for preventing cervical spondylosis, lumbar disc herniation and scapulohumeral periarthritis, and belongs to the technical field of beverages. The formula of the alcoholic beverage comprises the following components, by weight, 2-10 parts of mulberry, 2-10 parts of wolfberry fruit, 3-10 parts of Polygonatum sibiricum, 2-10 parts of dahurian angelica root, 2-10 parts of Peach Seed, 1-5 parts of safflower, 2-10 parts of Radix Puerariae, 2-10 parts of sophora japonica, 30-60 parts of distilled water, 5-10 parts of honey, and 100-200 parts of a white wine. The alcoholic beverage is compounded according to the traditional Chinese medicinal theoretic composition, has the efficacies of liver and kidney nourishing, blood circulation invigorating, vein relaxing and pain relieving, treats alcohol as a carrier, makes nutrients reach all corners of a body as possible by means of the diffusion performance of the wine, and especially reach positions comprising cervical vertebra, lumbar vertebra and shoulder joints which cannot be reached by routine aqueous solutions, and has the advantages of taking convenience, substantial improvement of the sleep condition of a patient, and benefiting for the physical and mental health of the patient.
Owner:XUZHOU GUPENG LIQUOR IND

Simulated work condition detecting method for 50,000 ton/year methionine propylene oxidation reactor

The invention relates to a simulated work condition detecting method for a 50,000 ton / year methionine propylene oxidation reactor. The method comprises the steps that air is blown to an oxidizer through an air blower, air is heated to the temperature of 160-170 DEG C by an air heater, inputted hot air can gradually increase the temperature of the oxidizer to 160 DEG C to meet the requirements for adding fused salt, two sections of the oxidizer are filled up with the fused salt successively, the temperature of the oxidizing section increases from 160 DEG C to 350 DEG C, the salt temperature of the reaction section increases to 350 DEG C to be insulated for more than or equal to 24 hours, and the temperature of a quenching section gradually increases to 300 DEG C to be insulated for more than or equal to 24 hours. When the temperature of the oxidizing section and the temperature of the quenching section increase by every 50 DEG C in a temperature rise process, whether fused salt leaks out of an upper pipe plate and a lower pipe plate is checked, thermal insulation is carried out for 24 hours, fused salt leakage is not observed to prove that the equipment quality meets production and using requirements, and then the temperature is slowly cooled down. In detection, the quality defect which cannot be found in cold mold detection of a traditional detecting method is overcome and repaired in time, and a lot of economical loss caused by shutdown and repair of the quality problem is avoided.
Owner:天津市化工设计院

Self-resetting opening device of switch cabinet operation mechanism

The invention discloses a self-resetting opening device of a switch cabinet operation mechanism. The self-resetting opening device comprises a mechanism body, a pin shaft, a first crank arm, a second crank arm, a mechanism output crank arm, a tension spring and a rotary opening knob, wherein a mechanism rotation shaft and a low-energy-cost trip coil are mounted on the mechanism body, a guide rod is arranged in the low-energy-cost trip coil, the pin shaft is mounted on the mechanism body, the first and second crank arms are mounted on the pin shaft in a sleeved manner, the second arm is in driving contact with a top rod in the low-energy-cost trip coil, the first crank arm drives the second crank arm to move during resetting, the mechanism output crank arm is mounted on the mechanism rotation shaft and revolves synchronously with the mechanism rotation shaft, two ends of the tension spring hang on the first crank arm and the mechanism output crank arm respectively, a barrier plate is arranged on the rotary opening knob, and the second crank arm is in driving contact with the barrier plate during opening. The self-resetting opening device of the switch cabinet operation mechanism has the advantage that the low-energy-cost trip coil can be reset through energy output of the mechanism body.
Owner:SHANGHAI PINGGAO TIANLING SWITCHGEAR CO LTD +2
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products