The invention provides a solid brewing yeast turning precisely-positioned mechanical hand control system and method. The system comprises a main controller, a camera, a laser range finder, a power supply module, a first photoelectric sensor, a second photoelectric sensor and a sub-controller, wherein the mechanical hand is provided with a first photoelectric sensor reflection plate and a second photoelectric sensor reflection plate; the first photoelectric sensor, the second photoelectric sensor and a third stepper motor driver are respectively connected with the sub-controller; a first stepper motor driver, a second stepper motor driver, a fourth stepper motor driver, a fifth stepper motor driver, an adjusting motor, a clamping stepper motor, the camera and the laser range finder are respectively connected with the main controller, and the sub-controller is connected with the main controller. The mechanical hand is firstly roughly positioned and then precisely positioned, so that the positioning time is greatly shortened, and the working efficiency is improved.