56 results about "Serous membrane" patented technology

A device and method for remodeling or partitioning a body cavity, hollow organ or tissue tract includes graspers operable to engage two or more sections of tissue within a body cavity and to draw the engaged tissue between a first and second members of a tissue remodeling tool. The two or more pinches of tissue are held in complete or partial alignment with one another as staples or other fasteners are driven t9hrough the pinches, thus forming a four-layer tissue plication. Over time, adhesions formed between the opposed serosal layers create strong bonds that can facilitate retention of the plication over extended durations, despite the forces imparted on them by stomach movement. A cut or cut-out may be formed in the plication during or separate from the stapling step to promote edge-to-edge healing effects that will enhance tissue knitting / adhesion.

A method, apparatus, and system are provided for mucous membrane therapy. The method includes receiving at least one body signal from a patient; detecting a condition of the patient based on the body signal; and administering the therapy to at least one of a mucous membrane or a serous membrane of the patient. A medical device system configured to implement the method is provided. A computer-readable storage device for storing instructions that, when executed by a processor, perform the method is also provided.

The invention discloses a method for manufacturing a medical apparatus, in particular to a method for manufacturing a soft brown biological collagen medical suture. The method for manufacturing the soft brown biological collagen medical suture is characterized by comprising the following steps: firstly, washing the inner wall of a fresh intestine and casing which has no disease after quarantine to be clean, performing coarse scrapping processing and delamination treatment on mucous membranes, serous membranes and mesenteries in the intestine and casing, and using a raising agent to perform loosening treatment; secondly, separating and cutting off fats in smooth muscle fibers and collagen fibers; thirdly, adding pyro into softened water, soaking fiber materials into the softened water for washing, and performing polymerization processing and setting treatment; and fourthly, using an automatic coreless grinding machine to perform processing and polishing, and performing suture and needle connection. The soft brown biological collagen medical suture has soft line body, easy operation, good positioning performance, high tensile strength and knotting strength and smooth suture-needle connection, reduces inflammation reaction during wound healing, and achieves perfect combination of the suture and a stitching needle.

A method, apparatus, and system are provided for mucous membrane therapy. The method includes receiving at least one body signal from a patient; detecting a condition of the patient based on the body signal; and administering the therapy to at least one of a mucous membrane or a serous membrane of the patient. A medical device system configured to implement the method is provided. A computer-readable storage device for storing instructions that, when executed by a processor, perform the method is also provided.

The present invention is an improved separating device for providing the malabsorptive component of a minimally invasive weight reduction system. This device may be a sleeve, liner, or tubular sheath that alters absorption of compositions through walls of hollow organs (stomach, intestines). The improvement involves better long-term retention through the ability of the device to engage with the interserosal fibrotic tissue formed in an intussusception. The separating device may be a distal extension of a retaining member that is directly engaged with and retained by intussuscepted tissue. Intussusception shrinks a hollow organ to provide a volume reducing restrictive component of a weight reduction system. Securing the separating device to an intussusception avoids retention problems of reference art devices as interserosal fibrosis helps secure the device. Also provided are an apparatus for retaining the device, a device and method for delivering the separating device, and a method for removing it.

The invention relates to a preparation method of two types of new biological patches, namely a muscle tendon patch and a small intestine serosa patch, and provides a natural biological patch material with favorable biomechanical characteristic and biocompatibility. The method comprises the following steps: acquiring muscle tendons and small intestine serosa of a pig as raw materials; utilizing a protective solution with a supporting structure capable of protecting the muscle tendons and the small intestine serosa during a whole decellularization process; performing predissociation on cells in tissues of the muscle tendons and the small intestine serosa by use of a high hydrostatic pressure technology; digesting residual cell nucleus by use of a composite nuclease method; removing loose and broken cell sheets by use of a detergent; rinsing with the protective solution. On the basis of thorough cell nucleus removal, the method is capable of being used for reducing the immunogenicity in the tissues of the muscle tendons and the small intestine serosa to the greatest extent and meanwhile reserving the three-dimensional structure and arrangement polarity of normal collagenous fibers of the tissues, and is applicable to tissue defect repair, tissue material filling and the like. Because of the characteristics of a biological fiber material, the new biological patches can also be widely applied to other biomedical domains.

Described are purified extracellular matrix materials isolated from the abdominal wall of animals and including the subserous fascia layer of the abdominal wall. Such medical materials can find use in treating damaged tissue and in certain aspects in providing tissue support for the repair of hernias. Related methods of manufacture and use are also described.

The invention discloses a removal process of intestinal tissues, barring casings, and ultrasonic transducer special for the removal process, which are mainly used for removing serosal layers, muscular layers and upper mucosal layers of intestines and attaching tissues such as fat, fascia and the like. The removal process includes: defining lower mucosal layers of the intestines as outermost layers; suck-drying the surface of each outermost layer; stretching the outermost layers tight on a fixing stick; closing an upper hemispherical head and a lower hemispherical head of a special noninvasive ultrasonic cavitation machine; irradiating the intestines by noninvasive ultrasound; and taking down and washing the intestines with water. The removal process is helpful for quickly removing intestinal tissues, barring casings, so as to obtain light, thin and transparent casings in good color. The removal process has the other advantage that implementing large-scale production by ultrasound improves production efficiency and promotes industrial development.

A method and device for manipulating gastric tissue about a greater curvature of a stomach. The method includes the steps of creating at least one incision to gain access to the peritoneal cavity, and dissecting at least a portion of the greater omentum. Then the method includes accessing the exterior of the gastric tissue through the incision and folding at least a portion of the greater curvature of the stomach. The fold is constructed having serosa to serosa contact substantially along its entire length. The method further involves securing the fold with a flexible member wherein the flexible member comprises at least one tissue securing feature.

The invention provides a natural tubular small intestine acellular matrix membrane and a preparation method thereof and belongs to the technical field of medical biomaterials. The method comprises washing small intestines taken from animals, sleeving an annular tubular support with the cleaned small intestines, breaking the serosa layer with scissors, scrapping the damaged small intestine serosa layer through an organic glass plate, turning over the small intestines, scrapping to remove the mucosal layer, submucosa and muscle layer of the small intestine, removing small intestine basal cells to obtain a single-layer tubular small intestine acellular matrix membrane, stacking the tubular small intestine acellular matrix membranes with the same specification on the support, carrying out pressing bonding to obtain a multi-layer tubular small intestine acellular matrix membrane, carrying out freeze-drying on the single-layer and multi-layer tubular small intestine acellular matrix membranes and carrying out sterilization preservation to obtain natural tubular small intestine acellular matrix membranes with different thickness. The preparation method has simple processes. The small intestine acellular matrix membrane is naturally tubular.

The invention provides a rectal cancer operation training model manufacturing method and a rectal cancer operation training model, and relates to the technical field of medical treatment. According to the manufacturing method of the rectal cancer operation training model, the stomach tissue is made into a barrel shape, one end simulates the anus end, the mucosa layer at the other end is connected with the rectum module to simulate the rectum of the human body, the serosal layer is fixed to the peritoneum, the serosal layer and the mucosa layer form the presacral space, and the stomach tissue is of a double-layer membrane structure and is close to the rectum in texture; the preparation method disclosed by the invention is simple and quick, the materials are convenient to take, and the cost is low. The rectal cancer surgery training model provided by the invention is manufactured by taking in-vitro stomach tissue, rectal tissue and peritoneum as raw materials, fully simulates the human rectal environment, can be used for training rectal cancer surgery, ensures feedback of training operation touch and strength, enables doctors to obtain real and convenient skill training, and improves surgical skills; meanwhile, the training environment is simplified, and investment of sites and labor is saved.

The invention relates to an ocular surface repair film and a preparation method thereof. The preparation method comprises: (1) taking pig small intestine jejunum section, cleaning, radially incision, removing mucosal layer, sarcolemma layer and serosa layer to obtain pig small intestine submucosa tissue membrane; The porcine small intestinal submucosa tissue membrane is respectively soaked in peracetic acid solution and sodium hydroxide solution, taken out and washed to obtain the acellular matrix of porcine small intestinal submucosa tissue; (3) soaking the porcine small intestinal submucosa obtained in step (2) with dopamine solution Tissue acellular matrix, the porcine small intestinal submucosa tissue acellular matrix material was obtained. The acellular matrix material of porcine small intestinal submucosa tissue obtained by the preparation method has relatively suitable mechanical hardness, and such mechanical hardness can ensure that the acellular matrix of porcine small intestinal submucosa tissue can be well attached to the ocular surface.

The invention discloses a bladder activity assisting device and an application method thereof. The device comprises a shrinkage film, a power device and a receptor. The shrinkage film is arranged in agap between a bladder detrussing muscle layer and a serosa layer. The receptor is attached to a detrusor muscle layer. The receptor is coupled with the power device. The power device is linked with the shrinkage film. The shrinkage film comprises a fixed film and an expansion film. The edges of the fixed film and the expansion film are fixedly connected with each other. A power liquid is filled in a containing space. The power device comprises a storage cavity used for storing the power liquid and a power pump arranged in the storage cavity. According to the bladder activity assisting devicedisclosed by the invention, through the arrangement of the shrinkage film, the power device and the receptor, the situation that the urine in the bladder is full of urine can be effectively and timelysensed by the receptor. After that, the power device drives the shrinkage film to shrink so as to assist in promoting the contraction and the urination of the bladder detrusor muscle.