51 results about "Gastrointestinal wall" patented technology

Devices and methods are provided for ablational treatment of regions of the digestive tract in post-bariatric surgery patients who fail to achieve or maintain the desired weight loss. Bariatric procedures include Roux-en-Y gastric bypass, biliopancreatic diversion, and sleeve gastrectomy. These procedures reconstruct gastrointestinal tract features, creating pouches, stoma, and tubes that restrict and / or divert the digestive flow. Post-surgical dilation of altered structures is common and diminishes their bariatric effectiveness. Ablation of compromised structures can reduce their size and compliance, restoring bariatric effectiveness. Ablation, as provided the invention, starts at the mucosa and penetrates deeper into the gastrointestinal wall in a controlled manner. Control may also be provided by a fractional ablation that ablates some tissue within a target region and leaves a portion substantially unaffected. Embodiments of the device include an ablational electrode array that spans 360 degrees and an array that spans an arc of less than 360 degrees.

Systems and methods are disclosed for the inversion of gastro intestinal diverticula and repair of associated intestinal wall tissue by means of endoscopy through a natural orifice such as the mouth or anus without making incisions in the abdominal wall or opening the peritoneal cavity.

Devices and methods are provided for the ablation of regions of the digestive tract to achieve hemostasis and to eradicate chronically bleeding lesions as occur with gastric antral vascular ectasia (GAVE), portal hypertensive gastropathy (PHG), radiation proctopathy and colopathy, arteriovenous malformations, and angiodysplasia. Ablation is typically provided in a wide-field manner, and in conjunction with sufficient pressure to achieve coaptive coagulation. Ablation, as provided the invention, starts at the mucosa and penetrates deeper into the gastrointestinal wall in a controlled manner. Ablation control may be exerted by way of electrode design and size, energy density, power density, number of applications, pattern of applications, and pressure. Control may also be provided by a fractional ablation that ablates some tissue within a target region and leaves a portion substantially unaffected. Embodiments of the device include an ablational electrode array that spans 360 degrees and an array that spans an arc of less than 360 degrees.

The present invention involves new interventional methods for reducing gastric volume, and thereby treating obesity. The procedures are generally performed laparoscopically and may generally be described as laparoscopic plication gastroplasty (LPG) in which, after obtaining abdominal access, spaced apart sites on a gastric wall are engaged, approximated and fastened to create one or more tissue folds forming one or more plications projecting into the gastrointestinal space. The serosal tissue may optionally be treated during the procedure to promote the formation of a strong serosa-to-serosa bond that ensures the long-term stability of the tissue plication. These procedures are preferably carried out entirely extragastrically (i.e. without penetrating through the gastrointestinal wall), thereby minimizing the risks of serious complications.

The invention discloses a method for preparing a cellulose gastrointestinal ultrasound angiography agent. Ethyl cellulose microspheres are firstly prepared; then a silicon oil defoamer is prepared; finally, the ethyl cellulose microspheres with a grain diameter of 20 microns and the silicon oil defoamer are mixed according to mass proportion of 1 to 100; thus the cellulose gastrointestinal ultrasound angiography agent is obtained. Due to the ability of eliminating gastrointestinal gases, the silicon oil defoamer can effectively eliminate artifacts caused by the interference of gases; evennessof a development image is determined by the grain diameter and the distribution of the ethyl cellulose microspheres; when the grain diameter is 20 microns and the distribution of the granularity is even, the ultrasound development effect is the best. The angiography agent of the invention not only ensures clear display of the structure of gastrointestinal wall, but helps to clearly distinguish surrounding organs and is expected to be used in clinical examination of gastrointestinal power.

The invention provides a separable capsule for detecting a disease marker in gastric fluid and acquiring a real image of the stomach. The separable capsule comprises a main cabin, an auxiliary cabin I and an auxiliary cabin II, wherein the main cabin comprises a wireless emission module, a micro battery, a power control module and a signal acquisition and control circuit; the auxiliary cabin I comprises an image acquisition image or a gastric fluid detection sensor; the auxiliary cabin II comprises an image acquisition circuit or a gastric fluid detection sensor; each image acquisition circuit comprises an LED lamp group, a CMOS sensor and a micro controller; the auxiliary cabin I and the auxiliary cabin II are connected and fixed with the main cabin through degradable fixing rings; after the degradable fixing rings are degraded, the auxiliary cabin I and the auxiliary cabin II are separated from the main cabin. The separable capsule provided by the invention can take a picture of a gastrointestinal wall and can also detect various disease markers; after the detection is completed, the two auxiliary cabins of the capsule are separated from the main cabin, so that the total size of the capsule is decreased, and the risk that the capsule cannot be discharged after entering a human body is effectively reduced.