57 results about "Sedative Effects" patented technology

A method of alleviating signs and symptoms of spasticity in human patient comprising orally administering to said human patients once in a day a controlled drug delivery system comprising an effective daily dose of baclofen or its pharmaceutically acceptable salt. The controlled drug delivery system is operable to produce a level of sedation lower than a sedation produced by three times a day immediate release tablets. A total daily dosage of the controlled release tablets and a total daily dosage of the three times a day immediate release tablets remain same.

The invention relates to a benzisoxazolyl piperidine derivative having the following general formula, a salt or a hydrate thereof,wherein R, X, Y, R′ and T are defined as in the specification. Such compounds have serotonin system modulating effects such as antagonizing effect on 5-HT2A and inhibitory effect on 5-HT reuptake. The compounds have good analgesic and sedative activities with mild toxic and side effects. The invention also relates to a composition comprising said derivative and the use thereof.

The invention relates to a medicine for curing the agraypnia, the effective content of the raw composition and the weight ratio as following: 5-7 shares of fruit orange magnoliavine, 13-15 shares of seed of spine date, 16-18 shares of licorice root, 23-25 shares of indian bread, 6-8 shares of indian bread and 15-17 shares of anemarrhena. The invention is characterized in that the invention has the efficiencies of tranquilizing property, relieving mental stress, replenishing qi and blood and nursing mind. The invention is applied for curing the agraypnia, the curative effect is great and the curative ratio is high. The invention has the advantages that the combination of the Chinese herbal medicine is applied; the invention has no toxic and side effects, no drug dependence; the preparation technology is simple and the drug administration is convenient.

The invention discloses tea with functions of calming the nerves and aiding sleep and a preparation method of the tea. The tea with functions of calming the nerves and aiding sleep is prepared by components in parts by weight as follows: 17-26 parts of lotus seeds, 7-11 parts of jujubes, 5-9 parts of millet, 4-6 parts of millet, 5-7 parts of melon seeds, 3-5 parts of walnut kernels, 4-6 parts of black sesame, 5-9 parts of lilies, 3-5 parts of smoked plum, 1-6 parts of cortex albiziae, 2-4 parts of poria cocos, 3-5 parts of radix astragali, 2-4 parts of angelica sinensis and 3-4 parts of bee honey. The tea with functions of calming the nerves and aiding sleep has the benefits as follows: the tea adopts natural herbaceous plants with functions of calming and sedation, the sleeping quality of people can be improved if the tea is taken for a long time, brain functions are adjusted, and the tea contains rich linoleic acid, amino acid, vitamin and the like, can tonify spleen, calm the nerves and adjust normal metabolism of brain cells and has no toxic and side effect on a human body.

The present invention provides pharmaceutical compositions comprising a flumazenil, and methods of alleviating or counteracting residual effects (e.g. drowsiness) associated with the administration of sleep / hypnotic drugs or alleviating effects of alcohol intoxication, using self administration modes of delivery.

Phenolic compounds with a phenolic molecule to which are covalently linked an oxygen-containing group, a nitrogen or another oxygen containing group, and a C1-C4 alkoxy group, or their precursor compounds, obtainable from monocotyledonous plants, or by chemical synthesis, have been found to calm and / or reduce anxiety and related behaviors and states in humans and animals. Additional chemical compounds of the present invention may include benzoxazinoids-cyclic hydroxyamic acids, lactams, and corresponding glucosides, which may serve as precursors to phenolic compounds. The phenolic compounds and precursors of phenolic compounds of the present invention, at concentrations suitable for human and animal therapeutic use, may be obtained from monocotyledonous plants such as corn in their early growth states which are timely harvested for optimum yield.

A formulation for anaesthetic use is described. The formulation contains propofol, and may be used to induce and / or maintain anaesthesia or sedation in a vertebrae. The formulation additionally contains a solvent or a combination of solvents and is suitable for mixing with commonly used infusion fluids prior to injection in to a patient. The formulation may be terminally sterilised using moist heat in order to assure sterility, and contains no lipid, thereby avoiding complications associated with administration over prolonged periods of time, or to patients with disorders of fat metabolism.

The invention discloses composite essential oil with an anti-insomnia effect. The composite essential oil is prepared by mixing 1-5 parts of rose essential oil, 1-5 parts of flores aurantii essentialoil, 1-5 parts of jasmine essential oil, 1-5 parts of sweet-scented osmanthus essential oil, 1-5 parts of michelia champaca essential oil, 1-5 parts of bergamot orange essential oil, 1-5 parts of lemon essential oil, 1-5 parts of mint essential oil, 1-5 parts of holly essential oil, 1-5 parts of pelargoniums essential oil, 1-5 parts of rosemary essential oil, 1-5 parts of cedar essential oil, 1-5parts of sandalwood essential oil, 1-5 parts of linalool, 1-5 parts of acetic acid lavender ester, 1-5 parts of phenethyl alcohol, 0.1-1.5 parts of radix angelicae sinensis essential oil, 0.1-1.5 parts of benzoin, 0.1-1.5 parts of mastic, 0.1-1.5 parts of a myrrh extract, 0.1-1.5 parts of a radix notoginseng extract, 0.1-1.0 part of chuanxiong rhizome essential oil, 0.1-1.0 part of saffron essential oil, 0.1-1.0 part of rhizoma nardostachyos essential oil, 0.1-1.0 part of a rhizoma paridis extract, 5-25 parts of glycerinum, 10-50 parts of edible alcohol and 10-25 parts of purified water. The composite essential oil is unique in composition, the making technology is simple, the application method is flexible and diverse, the composite essential oil has a good nerve calming and sedative effect, the tension mood can be relieved, the mood is adjusted, the composite essential oil is applied to household aromatherapy for improving the environment smell and has a certain bacterium inhibitionand pathogen transmission prevention function, more experience can be provided for a user, and different demands are met.

The invention relates to a new medical application of sinomenine. The invention provides the application of sinomenine as the sole active ingredient in the preparation of a medicine for treating chronic pain accompanied by depression behavior. The present invention uses a rat model of sciatic nerve compression injury, which manifests as chronic neurogenic pain and induces depressive behavior, and confirms that sinomenine has a good analgesic effect on chronic pain, and can improve its depressive-like behavior without tolerance Adverse reactions such as acceptability and sedative effect.

Compositions, systems, and methods that can be used with a pressurized metered dose inhaler are disclosed. A pharmaceutical composition for use in a pressurized metered dose inhaler can comprise a cannabinoid composition, a co-solvent, a terpene composition, and a propellant. A pharmaceutical composition may be soluble. A system can comprise a plurality of cannabinoid compositions and / or a plurality of terpene compositions available in various combinations. One of a plurality of cannabinoid compositions and terpene composition combinations may be user-selectable in response to various factors such as a desired therapeutic benefit, sedative effect, flavor profile, or a combination of the foregoing. A method of formulating a soluble pMDI pharmaceutical composition comprising a cannabinoid composition, a co-solvent, a terpene composition, and a propellant is disclosed.

The present invention relates to the technical field of refreshing agents, and discloses an air refreshing agent having a refreshing effect. The air refreshing agent is characterized by comprising the following raw materials by weight: 10-20% of lemon essential oil, 10-20% of a sweet orange extract, 10-20% of eucalyptus essential oil, 1-10% of a pericarpium citri reticulatae extract, 5-15% of ethanol, and the balance of deionized water. Compared with the air refreshing agent in the prior art, the air refreshing agent of the present invention has the following advantages that: characteristics of wide raw material sources, simple formula, plant aroma odor, no requirement of addition of essence, no pollution, no toxin and no harm are provided; the air refreshing agent contains the lemon essential oil so as to provide effects of refreshing, irritability-restlessness alleviating and air purification; the air refreshing agent contains the sweet orange extract so as to provide a calming effect, and the sweet orange essential oil having the sweet orange aroma has effects of nerve calming, decompression, physical and mental pleasure maintaining, and vitality increase so as to expel emotional tension and stress and improve insomnia caused by anxiety; and the ethanol is used for disinfection sterilization.

The present invention provides an oral pharmaceutical composition for the treatment of premature ejaculation, and the composition provides the effective and excellent treatment of premature ejaculation as well as reduced side effects like nausea, vomiting, drowsiness, sedation effect, awakening effect, and weight-loss etc.

The invention discloses a preparation method of a pharmaceutical composition with anti-anxiety effect, active pharmaceutical ingredients of the pharmaceutical composition comprise jatamans valeriana rhizome, silktree albizzia bark, spine date seed and rush, and the preparation method comprises the following steps: step 1) selecting the active pharmaceutical ingredients according to the proportion; step 2) crushing the jatamans valeriana rhizome into coarse powder, and extracting with ethanol; step 3) crushing the spine date seed and the silktree albizzia bark into the coarse powder, and extracting with water; step 4) extracting the rush with the ethanol. Simultaneously, the invention further discloses the preparation method of pharmaceutical composition capsules. A rat elevated plus-maze test, a rat vogel drinking conflict test, a spontaneous drinking test and a pain threshold test are performed on the pharmaceutical composition, and the test results show that the pharmaceutical composition has the obvious anti-anxiety effect and has no sedation or side effects.

A volatile refined oil for hypnotizing and improving sleep quality is prepared from grass-leaved sweetflag rhizome (60-90 wt.%) and ginger (10-40 wt.%). Its advantages are high effect, and no poison and irritation.

The invention discloses a traditional Chinese medicine composition with a function of resolving stagnation for tranquilization. The traditional Chinese medicine composition comprises the following raw material medicines in parts by weight: 10-15 parts of cortex albiziae, 10-20 parts of tuber fleeceflower stem, 10-20 parts of jujube kernel, 6-12 parts of lucid ganoderma, 15-30 parts of Astragalus membranaceus and 10-15 parts of Angelica sinensis. Animal and clinical experiments show that the traditional Chinese medicine composition has a good effect of inducing and prolonging sleep, exerts a good sedation effect while treating insomnia, and has a good curative effect to symptoms such as depression, anxiety and irritability. The traditional Chinese medicine composition is in particular suitable for the old, children and critical patients.

The invention discloses nerve soothing and sleep helping tea. The nerve soothing and sleep helping tea is prepared from, by weight, 68%-70% of walnut diaphragma juglandis, 4%-6% of pericarpium citri reticulatae, 8%-10% of flos rosae rugosae, 1%-3% of jujube kernels, 4%-5% of fructus crataegi, 2%-3% of flowers of prinsepia uniflora Batal. and 3%-5% of cape jasmine flowers. According to the nerve soothing and sleep helping tea, the natural Chinese herb plants which have nerve soothing and calming effects are selected, therefore, the sleep quality of people can be effectively improved, and a very good treatment effect on patients suffering from insomnia and dreaminess is achieved; the brain function can be adjusted; the tea contains rich linoleic acid, amino acid, vitamins and the like, therefore, the effects of tonifying the spleen and soothing the nerves can be achieved, normal metabolism of human brain cells can be adjusted, the good mental state of people can be kept, and no toxic or side effect is generated to a human body.