30 results about "Compression injury" patented technology

The invention relates to a continuous pickling and wiredrawing process of a brass wire, which is characterized in that: after being drawn out of a wire releasing disc, a brass wire blank is subjected to continuous processes of pickling, neutralizing, brushing, cleaning and wiredrawing. A continuous producing mode is used for connecting the pickling process and the drawing process of the brass wire together, namely that after an annealed brass wire blank is arranged on a wire releasing frame by one end of a production line, a finished product of the fine-drawn brass wire can be generated from the other end, therefore, the continuous producing mode has few processing and flowing processes and stops scrapes and compression injuries in the flowing process; pickled products are wiredrawn in a shorter period to ensure better brightness and consistency of product appearance and obviously increase the surface quality of the finished product of the brass wire; the processing process has high automation degree, reduces labor intensity of staffs and increases production efficiency; when the brass wire is in the pickling process, an oxide layer on the surface of the brass wire only needs to be loosened; and therefore, when the brass wire is pickled, nitric acid does not need to be added, the usage amount of acid liquor is greatly reduced, and the production cost is reduced.

The invention discloses a mammary machine compression device, which comprises a compression panel, a guide rail, a sliding block base and a compression bracket, and further comprises a first transmission device, a driving device, a brake, a manual unlocking device and a damper, wherein the sliding block base is arranged on the guide rail and is capable of moving up and down along the guide rail; the compression bracket is fixedly connected to the sliding block base; the first transmission device comprises a first belt wheel, a second belt wheel and a first synchronous belt; the first belt wheel is connected to the second belt wheel by virtue of the first synchronous belt; the first synchronous belt is contacted with the sliding block base and is capable of driving the sliding block base to move up and down; the driving device is connected to the first belt wheel; the brake is connected to the driving device and is used for braking the driving device in the case of power failure; the manual unlocking device is arranged on the compression bracket; and the damper is arranged on the manual unlocking device. The compression device disclosed by the invention is higher in transmission precision and is safer and reliable, and the compression device is capable of effectively reducing cost and reducing weight; in the case of power failure, the manual unlocking device is capable of releasing compression force, so as to avoid compression injury on patients; and the compression device is simple and convenient to operate, and is capable of meeting needs of clinical application.

The invention discloses an application of lncRNA (long non-coding ribonucleic acid) XR595534.2 in preparation of a medicine for treating or preventing chronic pain. According to the invention, trigeminal neuralgia induced by rat suborbital nerve chronic compression injury is taken as a pain model, a long-chain non-coding RNA gene lncRNA XR595534.2 with high specificity and difference expression in the model is obtained by screening, and interfering RNA for treating diseases taking lncRNA XR59534.2 as a target point is provided. The lncRNA XR595534.2 highly expressed in specificity and difference in a pain model is discovered for the first time, expression of the lncRNA XR59534.2 can be remarkably reduced by positioning injection of interfering RNA, pain behavior reaction is relieved, and the lncRNA XR595534.2 can be used for preparing medicines for preventing or treating prosopalgia, neuropathic pain, migraine and cancer pain.

The invention relates to a novel tissue hanger which comprises a central shaft 1, multiple supporting wires 2, a supporting wire fixing seat 3, a lifting button 4 and a puncture cone 5. The supportingwires are uniformly distributed around the central shaft 1, and the upper ends of the supporting wires 2 are fixedly connected with the supporting wire fixing seat 3 while the lower ends of the sameare fixedly connected with the lower end of the central shaft 1. The supporting wires 2 are made of elastic memory metal preferably, the lower end of each supporting wire is enabled to be arc-shaped by thermally processing the memory metal, and the lower end of each supporting wire made of the memory metal is maintained to be bent in an arc-shaped manner without external force. The novel tissue hanger has a puncture function, so that an extra puncture device is not needed, reliability of the hanger is improved, and compression injury to target tissue can be reduced.

The invention discloses an application of echinacoside (ECH) in preparation of a medicine for treating neuropathic pain. Experimental results show that when the ECH is used in a safe dosage range, theECH with the dosage of 200 mg / kg can remarkably relieve allodynia and hyperalgesia induced by a sciatic nerve chronic compression injury model, improve histopathological changes of sciatic nerves andregulate protein expression of inflammatory cytokines; and it is proved that the ECH has the effects of relieving the neuropathic pain caused by chronic compression injury and promoting the neural functional recovery.

The invention relates to application of 7-O-beta-D-acetylation sugar-coumarin compounds in treating chronic neuropathic pains. The 7-O-beta-D-acetylation sugar-coumarin compounds comprise a pharmaceutically acceptable salt, ester or a solvate thereof, and the application relates to the application of the salt, the ester or the solvate in preparing medicaments for treating the chronic neuropathic pains, wherein a glycosyl part is arbitrary pyranose or furanose, the hydroxy of which is totally acetylated; a representative compound is 7-O-beta-D-acetylation glucose-coumarin; and the structural formula is disclosed in the specification. On a classical sciatic nerve chronic compression injury (CCI) model, through single intragastric administration and continuous intragastric administration for 7 days, the compound shows definite treatment effect of resisting nervous pains. At a dose point appointed by an experiment, the compound can obviously improve the mechanical stimulus pain threshold, the nervous pain resistant efficacy is equivalent to that of Gabapentin which is a contrast medicament, and the duration is superior to that of the Gabapentin. Proved by research results, the compound can be used for treating the chronic neuropathic pains.

The invention provides a method for detecting pathogenic proteins of rice blast fungi, wherein a susceptible rice cultivar LTH is inoculated when a fourth leaf is completely unfolded; a compression injury patch with a diameter of 1 millimeter is formed on a widest position in the middle of the inoculated rice leaf by an injury device; proteins obtained after cultivation of a rice blast fungus - nitrogen hunger or recombinant expression of pathogenic genes are inoculated on the injury position, wherein the inoculation concentration of the proteins is 1 microgram per microliter, and the inoculation volume of the proteins is 3 microliters; and a scab formed on the rice leaf in 72 hours after inoculation is elliptical, and the longest value extended to the direction of the leaf apex and the leaf base is measured to be the length of the scab and is the basis for comparing the degree of pathogenicity of different proteins. The classification criteria of the proteins is as follows: the proteins have weak pathogenicity when the length of the scab is between 1.5 and 2 millimeters, have intermediate pathogenicity when the length of the scab is between 2.1 and 3 millimeters, and have strong pathogenicity when the length of the scab is more than 3.1 millimeters. The method has significance in research of the functions of pathogenic genes and the pathogenic proteins of the rice blast fungi.

The invention relates to a radiograph fulcrum pressurizer for lateral flexion of vertebral column. The invention has the technical scheme that one end of a propeller screw is fixedly connected with a knob, the other end of the propeller screw is connected with a telescopic rod, the other end of the telescopic rod is connected with a cross rod, and the other end of the cross rod is connected with a pressure plate. The invention solves the defects that standardization is difficult to perform because orthopedic force is not maximized and is instable, and the effectiveness and reliability are reduced. The invention has the effects that: the propeller installed on one side of an examining table enables the metal pressure plate to move forward and continuously pressurize the projecting points of scoliosis through a cushion pad, so that the form of the image of the scoliosis after correction is simulated, and a correction effect similar to that of implantation of an orthopedic material is achieved; the pressure measuring result can realize standardization of the photographical art operation; the pressure cushion pad pressurizes the projecting points of the scoliosis constantly, thus enabling the orthopedic force applied in vitro to be maximized; a patient is protected from compression injury due to too high pressure; and the problems of radioprotection and the like during auxiliary propelling are solved.

The invention discloses a stable anastomat firm in binding, and belongs to the technical field of medical instruments, the stable anastomat comprises a needle seat sleeve, a needle abutting seat is arranged on the side end face of the needle seat sleeve, a clock sleeve is fixedly connected to the side, close to the needle seat sleeve, of the needle abutting seat, and a pull rod sleeve grain is fixedly connected to the side, away from the needle abutting seat, of the clock sleeve. According to the invention, through the mutual cooperation of the designed structures such as the through hole, the threaded rod, the spring piece, the threaded safety piece, the clamping plate, the first external thread, the tightening nut, the anti-skid film, the bearing and the torsion spring, the device is more convenient, the force controllability is higher, and the stability is higher; and the stability of the fixed prepuce of the patient is improved by increasing the contact area with the prepuce of the patient, compared with a rope binding mode, more comfortable medical experience can be provided for the patient, on one hand, compression injuries caused to the prepuce of different patients due to the too large deformation degree can be avoided, and on the other hand, the stability of prepuce stapling for different patients can be ensured.

The invention discloses a neuroendoscopic craniocerebral surgical channel device, which comprises a protective sheath and an elastic film tube. The protective sheath comprises a movable half sheath and a fixed half sheath; the movable half sheath comprises a first half barrel, and the side wall of one end of the first half barrel is provided with a first handle in a radial extending manner; the fixed half sheath comprises a second half barrel, and the side wall of one end of the second half barrel is provided with a second handle in a radial extending manner; the tail end of the first handle and the tail end of the second handle are hinged mutually, and lateral openings of the first half barrel and the second half barrel are in opposite arrangement; the first handle is provided with a width adjusting structure, and the width adjusting structure can be driven to enable the first half barrel to move away from or close to the second half barrel; the elastic film tube is in a tubular structure and sleeves the outer surfaces of the movable half sheath and the fixed half sheath. The neuroendoscopic craniocerebral surgical channel device has advantages of simple structure and simplicity and convenience in operation; due to a closed state in puncture, brain tissues can be better protected, compression injuries are alleviated, and postsurgical complications and sequelae can be reduced.

The invention relates to an animal dorsal root ganglion-spinal cord fixed imaging and compression injury combining device, which comprises a dorsal root ganglion-spinal cord fixed imaging device and a microscopic fluorescent dye injection and spinal cord compression injury integrating device, wherein the animal dorsal root ganglion-spinal cord fixed imaging device (1) comprises a horizontal slide block guide rail (1-1), a fixing component (1-2), a slide rod (1-3) and a spine fixing clamp (1-4), and the microscopic fluorescent dye injection and spinal cord compression injury integrating device (2) comprises a vertical-rotating regulating side rod (2-3), a horizontal regulating component (2-4), a microscopic injection component (2-5) and a spinal cord compression component (2-6). The combining device has the advantages that multiple functions are integrated, the operation is simple and convenient, the switching can be realized at any time, different-degree spinal cord injury animal models can be conveniently manufactured, and after the fluorescent dye microscopic injection, a two-photon microscope is used for dynamically observing the pathological and physiological change process of the dorsal root ganglion-spinal cord injury in real time.

The invention discloses an implantable pressure-controllable micro-balloon spinal nerve compression device for small animals. The implantable pressure-controllable micro-balloon spinal nerve compression device comprises a liquid containing balloon, a pressing plate, an extrusion screw, a nut sleeve and a balloon catheter which are arranged in a subcutaneous tissue. The implantable pressure-controllable micro-balloon spinal nerve compression device is characterized in that the pressing plate is arranged above the liquid containing balloon, the extrusion screw penetrates through dermal tissue from the outside of the skin to abut against the upper portion of the pressing plate, the nut sleeve is arranged in the dermal tissue and sleeves the extrusion screw, and the balloon catheter communicates with the liquid containing balloon through a liquid guide pipe to guide liquid; and a pressure gauge is further arranged at the liquid inlet portion of the balloon catheter. The device disclosed by the invention can be used for simulating spinal nerve compression injury in animal experiments, is convenient to operate and controllable in force, and can also detect pressure and improve the accuracy of the experiments.

The invention provides a method for detecting pathogenic proteins of rice blast fungi, wherein a susceptible rice cultivar LTH is inoculated when a fourth leaf is completely unfolded; a compression injury patch with a diameter of 1 millimeter is formed on a widest position in the middle of the inoculated rice leaf by an injury device; proteins obtained after cultivation of a rice blast fungus - nitrogen hunger or recombinant expression of pathogenic genes are inoculated on the injury position, wherein the inoculation concentration of the proteins is 1 microgram per microliter, and the inoculation volume of the proteins is 3 microliters; and a scab formed on the rice leaf in 72 hours after inoculation is elliptical, and the longest value extended to the direction of the leaf apex and the leaf base is measured to be the length of the scab and is the basis for comparing the degree of pathogenicity of different proteins. The classification criteria of the proteins is as follows: the proteins have weak pathogenicity when the length of the scab is between 1.5 and 2 millimeters, have intermediate pathogenicity when the length of the scab is between 2.1 and 3 millimeters, and have strong pathogenicity when the length of the scab is more than 3.1 millimeters. The method has significance in research of the functions of pathogenic genes and the pathogenic proteins of the rice blast fungi.

The invention relates to 3-carbethoxy phenyl-beta-D-glucoside, or a pharmaceutically acceptable salt, ester or solvate thereof and application in preparing medicaments for treating neuropathic pains, wherein a glycosyl part is arbitrary pyranose or furanose; and a representative compound is 3-carbethoxy phenyl-beta-D-acylated xyloside the structural formula of which is disclosed in the specification. On a classical sciatic nerve chronic compression injury (CCI) model, through single intragastric administration and continuous intragastric administration for 7 days, the compound shows definite treatment effect on resisting nervous pains. At a dose point appointed by an experiment, the compound can obviously improve the mechanical stimulus pain threshold, the nervous pain resistant efficacy is equivalent to that of Gabapentin which is a contrast medicament, and the duration is superior to that of the Gabapentin. Proved by research results, the compound can be used for treating the chronic neuropathic pains.

The invention relates to the field of medical equipment, in particular to an anesthetic head fixing support suitable for prone position operations. The anesthetic head fixing support comprises a fixing support body, the fixing support body comprises a frame, a supporting device and a clamping device, the supporting device is used for adjusting a suitable head supporting position, and the clampingdevice is used for positioning the head. The anesthetic head fixing support is simple in structure, convenient to operate, capable of avoiding ventilation disorder or threaded pipe disengagement caused by swing of the patient's head in the anesthesia process, suitable for prone position operations, and capable of avoiding compression injury easily caused by long-time position placement to the patient's eyes, mouth or nose.

The invention relates to application of 7-O-beta-D-acetylation sugar-coumarin compounds in treating chronic neuropathic pains. The 7-O-beta-D-acetylation sugar-coumarin compounds comprise a pharmaceutically acceptable salt, ester or a solvate thereof, and the application relates to the application of the salt, the ester or the solvate in preparing medicaments for treating the chronic neuropathic pains, wherein a glycosyl part is arbitrary pyranose or furanose, the hydroxy of which is totally acetylated; a representative compound is 7-O-beta-D-acetylation glucose-coumarin; and the structural formula is disclosed in the specification. On a classical sciatic nerve chronic compression injury (CCI) model, through single intragastric administration and continuous intragastric administration for7 days, the compound shows definite treatment effect of resisting nervous pains. At a dose point appointed by an experiment, the compound can obviously improve the mechanical stimulus pain threshold,the nervous pain resistant efficacy is equivalent to that of Gabapentin which is a contrast medicament, and the duration is superior to that of the Gabapentin. Proved by research results, the compound can be used for treating the chronic neuropathic pains.

The invention relates to application of 2-fluroin-beta-D-glycoside compounds with a compound of the following formula as the ligand in preparing medicaments for treating neuropathic pain, , wherein the glycosyl part is any of pyranose or furanose, with the representative compound of 2-fluroin-beta-D-galactopyranoside which has the structural formula shown in the specification. The compound shows specific effect in treating neuropathic pain by single gastric infusion and continuous gastric infusion on a traditional sciatic nerve chronic compression injury model (CCI).

The invention discloses a pair of delivery forceps for the obstetrics department and a preparation method of a coating layer for the delivery forceps for the obstetrics department. The pair of delivery forceps for the obstetrics department comprises a forceps body, forceps blades arranged at the front end of the forceps body and used for including a fetal head, and forceps handles arranged at therear end of the forceps body, and the inner side surfaces of the forceps blade are provided with coating layers prepared from polydimethylsiloxane / hydrophilic silica polymer nanocomposite material, wherein the coating layer is prepared through solution preparation, internal mold processing and compression molding. The pair of delivery forceps for the obstetrics department is used for solving the problems of fetal head slippery caused by poor control over delivery forceps clamping force or too large tensile force, reduction of fetal head compression injury due to too large clamping force and the like, and the pair of delivery forceps for the obstetrics department has the advantages of moderate compliance, simple structure, convenient use, safety, sanitation and the like.

The invention relates to application of 4-formylphenyl-beta-D-glucoside compounds in treating chronic neuropathic pains, which uses a compound of the formula (disclosed in the specification) as a ligand, wherein a glycosyl part is arbitrary pyranose or furanose; the 4-formylphenyl-beta-D-glucoside compounds comprise a pharmaceutically acceptable salt, ester and a solvate, and the application relates to the application the salt, the ester and the solvate in preparing medicaments for treating the neuropathic pains; a representative compound is 4-formylphenyl-beta-D-xyloside; and the structural formula is disclosed in the specification. On a classical sciatic nerve chronic compression injury (CCI) model, through single intragastric administration and continuous intragastric administration for 7 days, the compound shows definite treatment effect on resisting nervous pains. At a dose point appointed by an experiment, the compound can obviously improve the mechanical stimulus pain threshold, the nervous pain resistant efficacy is equivalent to that of Gabapentin which is a contrast medicament, and the duration is superior to that of the Gabapentin. Proved by research results, the compound can be used for treating the chronic neuropathic pains.

The invention relates to the field of laparoscopic surgery, and particularly relates to an individual operation type laparoscopic surgical instrument structure. The laparoscopic surgical instrument structure comprises a mounting cylinder, a mounting sleeve box and a tubular needle. A handle and a wrench are arranged at the bottom of the mounting cylinder. The mounting cylinder is internally provided with a CCD photosensitive element, an image acquisition card, a storage battery and a connection processor. The CCD photosensitive element, the image acquisition card, the storage battery, the connection processor and a USB interface are electrically connected in sequence. The mounting sleeve box is arranged on one side of the mounting cylinder. One end of the mounting sleeve box is connected with an elastic corrugated pipe of which the other end is connected with a protection pad. The tubular needle is arranged at the end, close to the mounting sleeve box, of the mounting cylinder. The tubular needle penetrates through the protection pad. The protective pad is in contact with the abdominal skin of a patient. A telescopic rod and a spring can provide given buffering force, so that the abdomen of the patient cannot be in contact with the mounting cylinder, thereby avoiding compression injury to the abdomen of the patient due to compressive rotation of the mounting cylinder.

The invention relates to the technical field of animal experiment instruments, in particular to a mouse spinal cord injury composite experiment device and a using method thereof. The latter comprises a blunt contusion simulation experiment and a compression injury simulation experiment. The device is reasonable and compact in structure and convenient to use, by arranging the needle cylinder and the striking piece, if the striking piece is put into the needle cylinder from the inner side of the upper end of the needle cylinder, after the striking piece does falling motion in the needle cylinder, the lower end of the striking piece strikes the spinal cord of a mouse to simulate blunt contusion, and the lower end of the striking piece directly presses the spinal cord of the mouse for a period of time to simulate compression injury; meanwhile, through the arrangement of the front accommodating body groove and the rear accommodating body groove, the spine of the mouse can be naturally bent, the spinal cord of the mouse can be more clearly exposed, accurate hitting or pressing of the hitting piece is achieved, repeated purchasing of related experimental equipment can be avoided by using the device, the purchasing cost is greatly saved, and related experiments conducted through the device are good in repeatability and high in practicability. And experimental data can be collected to establish a related experimental model.

The invention relates to 3-carbethoxy phenyl-beta-D-glucoside, or a pharmaceutically acceptable salt, ester or solvate thereof and application in preparing medicaments for treating neuropathic pains, wherein a glycosyl part is arbitrary pyranose or furanose; and a representative compound is 3-carbethoxy phenyl-beta-D-acylated xyloside the structural formula of which is disclosed in the specification. On a classical sciatic nerve chronic compression injury (CCI) model, through single intragastric administration and continuous intragastric administration for 7 days, the compound shows definite treatment effect on resisting nervous pains. At a dose point appointed by an experiment, the compound can obviously improve the mechanical stimulus pain threshold, the nervous pain resistant efficacy is equivalent to that of Gabapentin which is a contrast medicament, and the duration is superior to that of the Gabapentin. Proved by research results, the compound can be used for treating the chronic neuropathic pains.

The invention discloses a self-wearing mechanism for a breathing mask and monitoring equipment based on the self-wearing mechanism. The self-wearing mechanism includes a latex layer for improving theadhesion between the breathing mask and face, and the latex layer is internally provided with an elastic part capable of elastically supporting the latex layer to stick to the face, when the elastic part is elastically tightened, the breathing mask is fully fitted to the face, the latex layer is high in protection, and soft and comfortable when fitted to the face, compression injuries are not caused, a supporting tube supporting the breathing mask and capable of being plastically deformed is arranged above the breathing mask, the position of the breathing mask is adjusted when the supporting tube is plastically deformed, the supporting tube replaces an existing method of using elastic strings to tie the breathing mask to head or fixed on ears, tighten injuries are not caused, the supporting tube is conveniently and manually adjusted to realize the fixation of the breathing mask, touching of the body of a patient is not needed, that situation that the patient with the infectious diseasetransmits the infectious disease to a medical staff is avoided, and the safety is high.

The invention discloses an application of nobiletin (NOB) in preparation of a medicine for treating neuropathic pain. Experimental results show that when the traditional Chinese medicine composition is used in a safe dosage range, hyperalgesia hypersensitivity and hyperalgesia induced by a sciatic nerve chronic compression injury model can be remarkably relieved, histopathologic changes of sciatic nerves are improved, and expression of pain related factors is regulated and controlled; the nobiletin is proved to have the functions of relieving neuropathic pain caused by chronic compression injury and promoting neurological function recovery.

The invention relates to the technical field of medical equipment in the obstetrics and gynecology department, and discloses an obstetrics and gynecology department post-cesarean wound nursing device which comprises a shell, a pneumatic device is fixedly connected to the interior of the shell, a first pipeline is fixedly connected to the outer side of the pneumatic device, and a first shell is fixedly connected to one end of the first pipeline; and a supporting piece is fixedly connected to the outer side of the first shell, a first sliding block is slidably connected to the interior of the supporting piece, and a first connecting shaft is fixedly connected to the interior of the first sliding block. According to the obstetrics and gynecology department post-cesarean wound nursing device, through connection of the shell and the first connecting shaft, the problem of compression injury caused by movement during postpartum nursing of a pregnant woman is solved, through pneumatic accurate control, the pregnant woman can lie flat for rest and move a wheelchair conveniently, the practicability of the device is improved, the intelligence of the device is improved, automatic replacement is achieved through a mechanical device, secondary injury is avoided, and wound adhesion is not prone to occurring.

The invention relates to a non-laparoscopic pneumoperitoneum hanger. The non-laparoscopic pneumoperitoneum hanger is provided with a stand column; the stand column is connected with a cross rod with the height capable of being adjusted in a lifting mode; a lifting pipe made of a hard material is installed on the cross rod; the lifting pipe is provided with an instrument channel capable of allowinga surgical instrument to penetrate through; and the lower part of the lifting pipe is provided with a supporting ring which can be arranged in the abdominal wall of the human body, can rise and fallalong with the cross rod to arch the abdominal wall upwards and is made of an elastic material. The abdominal wall of a patient is supported by the supporting ring to form an operation space in the abdominal wall, so that compression injury to the viscera of the patient due to direct inflation in the abdominal wall during a traditional laparoscopic operation is effectively prevented; and the surgical instrument can directly reach a surgical site through the instrument channel, so that an opening for inserting the surgical instrument does not need to be additionally formed, the consistency of an instrument inserting site and the surgical site is ensured, and the smooth operation is facilitated.

The invention provides a tourniquet based on blood pressure automatic adjustment, and relates to the field of medical instruments. The tourniquet based on blood pressure automatic adjustment comprisesa cuff, a blood pressure measuring device and a control device; an air room is formed in the cuff; the blood pressure measuring device measures blood pressure based on a photoplethysmography method,and the measured blood pressure is output into the control device; the control device controls pumping and discharging of air in the air room based on the measured blood pressure, so that pressure, exerted on the limbs, of the tourniquet is controlled. According to the tourniquet based on blood pressure automatic adjustment, the pressure of the tourniquet can be adjusted based on the blood pressure, and on the premise that the demand for hemostasis is met, compression injuries of the tourniquet on a patient are reduced.