The invention discloses artemisia anomala Chinese-western medicine composite bone-strengthening pain-easing oral liquid and a preparation method thereof. The oral liquid is mainly prepared from artemisia anomala, sassafras, hylotelephium telephium, flat-stemmed tetrastigma, goat-ear elecampane, Fusong monkshood, macaque bone, swida macrophylla, dillseed, ophisaurus harti, straw mushroom, armillaria mellea, wild soybeans, ruddle, tibet lyonia, mucuna birdwoodiana, crayfish, caryota ochlandra, omei linden root-bark, rubus coreanus miq (roots), chrysophyllumlanceolatum, potentilla davica, Chinese carlesia, leptin, 4-hydroxy-3-methoxybenzoic acid, beta-sitosterol, taurine and alginic acid. The oral liquid has the effects of activating blood circulation and dredging collaterals, nourishing and tonifying qi, strengthening tendons and bones, relaxing muscles and tendons and relieving pain, and invigorating the spleen and benefiting the stomach. The oral liquid can effectively relieve pain of patients, can accelerate fluorine emission, greatly improves the symptoms of whole body muscular pain, dizziness, palpitation, weakness, tiredness, anorexia, nausea, emesis, abdominal distension, diarrhea or constipation and the like, and achieves the aim of treating both the symptoms and root causes.