The invention discloses a radioactive dirt-removing high-strength strippable film as well as a preparation method and application thereof. The invention aims to solve the problems that the existing stripping type pressing dirt removing agent is mainly applied to pressing and removal of large-area radioactive fallout materials and has certain limitation on removal of loose pollution. The radioactive dirt-removing high-strength strippable film is prepared from the following raw materials in percentage by weight: 50 to 70 percent of polyisoprene, 0.3 to 3 percent of sulfur, 0.25 to 3 percent of nanometer white carbon black, 0.3 to 2 percent of an accelerant ZDC, 0.5 to 2 percent of an anti-ageing agent, 0.1 to 1 percent of zinc oxide, 0.05 to 1.0 percent of casein, 0.5 to 2 percent of EDTA, 0.02 to 0.5 percent of a dispersing agent BX, 20 to 40 percent of water and the like. The polyisoprene base material is subjected to vulcanization modification and is compounded with other components to obtain the radioactive dirt-removing high-strength strippable film, and the defects that the original strippable film has insufficient strength and is not liable to strip are effectively overcome. Through actual verification, the strippable dirt-removing agent has high film-forming strength and the tensile strength can reach 110 kg / cm<2>; and furthermore, in actual application, the surface pollution can be removed to below the clearance level (less than 0.08 Bq / cm<2>), and remarkable progressive significance is achieved.