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45 results about "Pulmonary inhalation" patented technology

Proanthocyanidin sustained release nano-micro spheres, as well as preparation method and application thereof

The invention relates to proanthocyanidin sustained release nano-micro spheres. The proanthocyanidin sustained release nano-micro spheres comprise 1-5 parts of proanthocyanidin, 1-12 parts of chitosan or derivatives thereof, 1-12 parts of phospholipid or derivatives thereof and 1-10 parts of excipients, wherein the chitosan and the derivatives thereof are one or more of high, medium and low-molecular weight chitosan, chitosan oligosaccharide, chitosan quaternary ammonium salt and carboxymethyl chitosan. The particle size of the proanthocyanidin sustained release nano-micro spheres is 10nm-0.3 mu m; the proanthocyanidin is prepared into the powder sustained release nano-micro spheres, and the proanthocyanidin sustained release nano-micro spheres can directly play a role in the lung as a pulmonary inhalation medicine-carrying formulation, improve the bioavailability of the proanthocyanidin and reduce the dosage by sustained release; the proanthocyanidin nano-micro spheres can also be applied as an oral sustained release formulation; the proanthocyanidin nano-micro spheres have appropriate particle size and morphology and other powder properties, as well as sustained release; furthermore, the preparation method has the advantages of simplicity and convenience in operation, stable process and easiness in industrial production.
Owner:WEIFANG MEDICAL UNIV

Insulin powder spray for lung inhalation and preparation method thereof

InactiveCN101474399AEnhance hypoglycemic functionPowder deliveryPeptide/protein ingredientsAngle of reposeSolubility
The invention relates to the field of pharmaceutical preparation, in particular to insulin powder inhalation absorbed in lung through mouth. The invention is characterized in that the insulin powder inhalation consists of insulin, mannite, amino acid and lung surface active substances. The insulin powder inhalation has the advantages of high bioavailability, good safety, and better solubility, bulk density, angle of repose and atomizing property, and is not easy to absorb moisture.
Owner:CHINA PHARM UNIV

Inhalation training instrument for pulmonary inhalation administration

The invention belongs to the technical field of medical instruments and provides an inhalation training instrument for pulmonary inhalation administration. The inhalation training instrument comprisesa tank, an inhalation cylinder, a resistance regulator, a flow sensor, a signal converter and a data analysis part. The inhalation cylinder can rotate around the axis of the tank. Along with rotationof the inhalation cylinder, fan-shaped regulating holes in the resistance regulator coincide with different vent holes, so that resistance borne by airflow is regulated, the flow sensor measures actual flow, the actual flow is converted by the signal converter and then transmitted to the data analysis part, the data analysis part calculates inhalation acceleration, inhalation peak flow velocity and inhalation volume according to flow data, and the data are displayed through a displayer of the data analysis part. According to the inhalation training instrument for pulmonary inhalation administration, the data results such as the inhalation acceleration, the inhalation peak flow velocity and the inhalation volume are visualized, a patient is helped to train the inhalation mode, the pulmonary deposition rate of medicine and the uniformity of delivery dosage are improved, and the patient can obtain a better treatment effect in inhalation medicine treatment.
Owner:张玮
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