55 results about "Pathology Examination" patented technology

A pathological diagnosis support device, a pathological diagnosis support program, a pathological diagnosis support method, and a pathological diagnosis support system extract a pathological tissue for diagnosis from a pathological image and diagnose the pathological tissue. A tissue collected in a pathological inspection is stained using, for example, hematoxylin and eosin. In consideration of the state of the tissue in which a cell nucleus and its peripheral constituent items are stained in respective colors unique thereto, subimages such as a cell nucleus, a pore, cytoplasm, interstitium are extracted from the pathological image, and color information of the cell nucleus is also extracted. The subimages and the color information are stored as feature candidates so that presence or absence of a tumor and benignity or malignity of the tumor are determined.

The invention relates to a thyroid CT image computer-aided diagnosis system and method. The problem that currently, many defects exist in the thyroid disease diagnosis through physical examination, ultrasonic scanning and radioisotope scanning is solved. The system comprises an input module, an image texture characteristic extracting module, a classified diagnosis module and an output module which are sequentially connected. The method includes the steps of conducting outline segmenting and extracting on an image, then conducting texture characteristic analysis on the image to obtain the 28-dimension texture characteristic, and finally substituting the 28-dimension texture characteristic into a diagnosis model to obtain a diagnosis result and a statistics index. The thyroid CT image computer-aided diagnosis system and method have the advantages that non-invasiveness, rapidness and timeliness are achieved; no chemical reagents or the like are needed, and cost is low; complexity of a lesion thyroid texture characteristic sample set is effectively reduced, and identification accuracy can be further improved; the result is not affected by man-made subjective factors and is prevented from being affected by man-made subjective factors in the pathological examination and other examinations.

Guided biopsy is a commonly used method to remove suspicious tissues from an internal organ for pathological tests so that malignancy can be established. Provided herein are systems and methods (i.e., utilities) that allow for automated application of one or more predefined biopsy target plans to an acquired medical image including without limitation, an ultrasound prostate image. Due to different shapes and sizes of prostates as well as orientation of prostate with respect to an ultrasound probe during image, acquisition a simple prostate model (e.g., ellipse) with a fixed plan may not be sufficient. Accordingly, it has been determined that a deformable shape model with integrated biopsy target locations/sites may be fit to a prostate image to provide improved automated biopsy targeting.

The present invention is one kind of reagent for quick immune histohcemical detection of lymphatic metastasis of mammary cancer and corresponding detecting method. Several kinds of directly marked antibody capable of distinguishing metastatic cancer cell and inherent lymph node cell are mixed into reagent and one-step reacted to stain the metastatic cancer cell in lymph node specifically. The present invention is used in the fast pathological diagnosis of early lymphatic metastasis of mammary cancer, and has raised sensitivity, high accuracy and high specificity.

A position of a pathological examination on a radiographic image, such as a CT image and an MRI image, is stored beforehand in association with the radiographic image. When the radiographic image is displayed on a monitor device, a marker indicating the position of the pathological examination, which is stored in association with the human body image, is displayed at a corresponding position on the radiographic image displayed on the monitor device. Further, information (a pathology image and a pathology report) on the pathological examination of a tissue collected from the position of the pathological examination is displayed simultaneously with the radiographic image. Therefore, the position of the pathological examination can be accurately grasped on the radiographic image, and the correspondence relationship between the image at the position (biopsy site) of the pathological examination on the radiographic image, and the information on the pathological examination can be clearly grasped.

The invention discloses a portable fundus camera used for pathological examination on fundi of human eyes medically. Images of the fundi of the human eyes are obtained through an optical imaging method, and therefore fundus pathologies and focuses can be judged.

The invention discloses an active monitoring and early warning system of infectious diseases in a medical institution. The active monitoring and early warning system comprises a diagnosis data rule base, an inspection index rule base and an image and pathologic examination rule base. According to the active monitoring and early warning system, influences, caused by personal factors, on monitoring of the infectious diseases in the medical institution are reduced to the greatest extent; a manual monitoring mode is changed so that disease monitoring can be seamlessly integrated with an existing information system of a hospital; intelligent monitoring and whole-course monitoring of the infectious diseases are realized; the missing report rate and late reporting rate of the infectious diseases, especially major infectious diseases, are reduced; the monitoring management efficiency on the infectious diseases of the medical institution is improved.

The invention provides a remote dynamic pathological diagnosis method, and relates to the technical field of pathological diagnosis. The remote dynamic pathological diagnosis method comprises the steps that S1 a remote dynamic pathological examination hospital is established in cities or villages with backward medical standards; a remote diagnosis cloud platform is set up for the remote dynamic pathological examination hospital; well-known experts from all over the country are invited to join the remote diagnosis cloud platform; and data synchronization and sharing are realized between the hospital terminal and expert terminals and between various expert terminals. By establishing the remote dynamic pathological examination hospital and connecting the remote dynamic pathological examination hospital with experts and patients, the patients can be diagnosed without a relevant disease expert in the local area, which prevents the patients from going to a remote clinic. The efficiency of patient consultation is greatly improved. In many areas where medical conditions are relatively backward and related expert resources are scanty, the remote pathological diagnosis technology can be usedto improve medical conditions.

The invention discloses application of donkey-hide gelatin in preparing haze-prevention medicine or health-care products and belongs to the field of new medical application of donkey-hide gelatin.According to the application, SD rats inhale air fine particles in consecutive eight weeks, the rats are subject to gavage with different dosages of donkey-hide gelatin solutions for medicine intervention while contaminated, and the damage mechanism generated by toxicity and the protection effect mechanism of donkey-hide gelatin on respiratory system damage caused by air fine particles are studied from weight, organ coefficients and lung functions in combination with the aspects of hematology, blood biochemical index measurement, respiratory functions, tissue pathology examinations and oxidation damage.It is found through experiment results that donkey-hide gelatin can effectively decrease the content of malondialdehyde and the number of lung phagocytic cells and increase the content of glutathion peroxidase, definite relieving effects are achieved on rat lung function and lung pathologic changes caused by air fine particles, and donkey-hide gelatin can be used for preparing haze-prevention medicine or health-care products.

The invention discloses a ureter ligation induced non-human primate animal renal fibrosis model building method and application. The specific technical scheme includes that an experimental monkey is anaesthetized by anesthetics, surgical anesthesia is maintained, the abdomen of the experimental monkey is cut apart along a medioventral line after disinfection, an abdominal cavity is opened, an operation field is exposed, a unilateral ureter at a unilateral renal lower edge is ligated twice by a surgical silk thread and completely blocked, another kidney is not ligated and serves as a self-body for comparison, a wound is stitched in a layered manner after a surgical incision is disinfected, renal fibrosis indexes are measured by biological samples at different time points after ligation, or a left kidney and a right kidney are taken down and fixed in neutral buffered formalin, and formalin fixed kidney samples are subjected to tissue section and pathological examination. An animal model has application values which cannot be realized by an existing rodent and rabbit animal model, and the non-human primate animal model built by the method has wide application in related fields of fibrosis.

The invention discloses a sample taking-out device for assisting a colonoscopic surgery in the technical field of medical care equipment. The sample taking-out device comprises an object taking pipe,wherein a sleeve is sleeved and connected onto the outer wall of the object taking pipe; three support plates are uniformly arranged at the bottom of the outer wall of the object taking pipe; a position limiting ring is arranged on the top of the outer wall of the object taking pipe; three linkage plates are uniformly arranged in the middle part of the outer wall of the sleeve; the other ends of the linkage plates and the other ends of the support plates are provided with annular expansion plates; a rubber ring is sleeved and connected onto the top of the outer wall of the sleeve; three connecting rods are uniformly installed on the top of the rubber ring; connecting pipes are arranged on the tops of the three connecting rods; an anti-slip sleeve is sleeved and connected onto the outer wall of the connecting pipe; through the combination of devices of the expansion plate, the sleeve, the linkage plate and the like arranged on the device, the expansion on the anus is convenient; the crissum muscle contraction is relieved; the taking of giant adenoma is convenient; the influence on pathological examination is reduced.

The invention discloses a tumor tissue pathology classification system and method based on adaptive proportional learning, and the method comprises the steps: firstly obtaining a plurality of pathological sections, carrying out the digital scanning, carrying out the manual marking of a scanned pathological image according to a classification task target category, and constructing a data set; segmenting the tissue foreground by using the difference distribution characteristics of RGB channels and gray values, and constructing a training data set of image blocks containing multi-stage magnification times; and finally, performing multi-stage amplification factor integration, combining the cross moisture function of each stage of amplification factor and the integration amplification factor to form a loss function, and achieving multi-amplification factor integration learning; and through adaptive proportion learning, performing dynamic adjustment on image global proportion labels and image block training weights which do not reach the lowest proportion, and therefore, the data utilization rate is increased, and rapid convergence is realized. In the pathological examination of daily tumor tissues, the detection rate is improved to the greatest extent on the basis of increasing extra workload as low as possible.

The invention provides a medical technology department workload evaluation method based on labor division in the field of performance evaluation. The medical technology department workload evaluationmethod comprises the following steps: step S10, dividing a medical technology department into a clinical laboratory, an ultrasonic department, a pathological examination department, an imaging department and a nuclear medicine department; s20, respectively setting work score calculation formulas of the clinical laboratory, the ultrasonic department, the pathological examination department, the imaging department and the nuclear medicine department; and S30, respectively calculating the work scores of a clinical laboratory, an ultrasonic department, a pathological examination department, an imaging department and a nuclear medicine department according to the work score calculation formula, and evaluating the workload of a medical technology department by utilizing the work scores. The method has the advantages that the reasonability of medical technology department workload evaluation is greatly improved, the labor value of medical technology department personnel is fully reflected, the work enthusiasm is improved, and the development of projects with high technical difficulty is promoted.

The invention discloses a negative pressure conveying pathological examination full-process system for an infectious specimen. The negative pressure conveying pathological examination full-process system for the infectious specimen comprises a corpse dissecting chamber, a visceral organ specimen sampling chamber, a sampled specimen retention chamber, a pathological technology chamber and a monitoring control chamber, wherein the corpse dissecting chamber, the visceral organ specimen sampling chamber and the pathological technology chamber are in one-way communication through a flow line systemand a conveying passage; the negative pressure in each chamber is gradually reduced, so that internal gas is in one-way flow; the visceral organ specimen sampling chamber is in two-way communicationwith the sampled specimen retention chamber through a flow line system and a conveying passage; the monitoring control chamber communicates with each chamber through a video conversation system and aremote operation system; graphic and text information of the pathological examination is uploaded to a pathological data analysis center through a wireless information system; and air intake exhaust and purification systems are arranged at the ends of the corpse dissecting chamber and the pathological technology chamber. The negative pressure closed pathological anatomy material taking system in an automatic flow line mode designed according to the invention is suitable for being applied to pathological examination of visceral organs and tissues.

The invention discloses a PET/CT automatic lung cancer diagnosis classification model training method based on pathological feature assistance, and belongs to the field of medical images. The method comprises the following steps: training a classification network of pathological images to preferentially obtain a group of better pathological classification network model parameters; and obtaining the feature information of the pathological image through the group of parameters to guide feature extraction of the PET/CT image classification network, so that the precision of the PET/CT image classification network is improved, popularization and application of early lung cancer diagnosis and classification based on PET/CT images are facilitated, and help is provided for diagnosis and subsequent follow-up visit of clinicians. According to the invention, before the subsequent invasive pathological examination is not carried out, a more accurate lung cancer diagnosis classification result close to a pathological diagnosis result can be achieved only through a noninvasive PET/CT image, so that the diagnosis efficiency of a clinician can be effectively improved, and the wound of a patient is reduced.