37 results about "Oral therapy" patented technology

The invention discloses a health-care electronic cigarette liquid for medical use, which mainly comprises: 3-5%w / v of tobacco leaf extract, 40-50%w / v of propanediol, 10-15%w / v of pure water, 3-5%w / v of tobacco essence, 0.2-1.0%w / v of stabilizer, 3-8%w / v of thickener, 15-20%w / v of medicament. Because of no harm of second-hand smoke, the invention can be used at public places without influence to body health of others. The invention is capable of treating cough, hacking cough, itchy throat, abundant expectoration, sensitive cough cause by acute upper respiratory tract infection of fever, influenza or the like while enjoying smoking, having treatment function to oral therapy, cough relieving, nasal and pharyngeal mucosa congestive swelling relieving and sneezing.

The present invention relates to novel ramipril crystalline particles with improved stability and bioavailability. More particularly, the present invention is directed to individually coated, single ramipril crystalline particles for pharmaceutical and biopharmaceutical applications in oral therapies that are stabilized against decomposition into degradation products, namely, ramipril-DKP and ramipril-diacid, during formulation and storage conditions. The present invention also relates to stabilized ramipril pharmaceutical compositions, novel anhydrous pharmaceutical grade ramipril powders, methods for improving ramipril bioavailability, and methods of manufacture and stabilization of ramipril formulations. The novel, anhydrous pharmaceutical grade ramipril powders and ramipril compositions and dosage forms formed therewith are useful in the treatment of cardiovascular disorders and have the advantage that they provide greater stability against decomposition into ramipril-DKPs and ramipril-diacids under formulation and storage conditions. In addition, they maintain consistent label ramipril potency over extended shelf-life and provide reduced in vivo variability in the bioavailability of ramipril among subjects when administered orally.

The present invention relates to methods of treating or reducing the risk of necrotizing enterocolitis (NEC) in an infant comprising orally administering an effective amount of a CpG-ODN. It is based, at least in part, on the results of experiments in which orally administered CpG-ODNs were observed to reduce the histopathology and markers of inflammation in a murine model for NEC. The present invention further provides for oral formulations of CpG-ODN for administration to infants.

The invention discloses a multifunctional oral therapy instrument, which comprises a vibrator, a connecting component and an up-down integrated denture base. The connecting component connects the denture base and a vibration output head of the vibrator; the vibration output head has two directional vibration directions, one direction is vertical to the plane where the denture base is, while the other direction is parallel to the midline of the denture base. An upper denture base and a lower denture base of the up-down integrated denture base encase the upper denture and the lower denture respectively. Under the action of the vibrator, the denture base can realize the directional vibration from the up down and from front to back. The therapy instrument can be widely applied to the clinical oral therapy; different accessories arranged in the denture base can bring about different therapy effects; the inner wall and bottom surface of the denture base are provided with bristles, so the tooth can be cleaned through the brushing movement generated by the vibration; as the inner wall of the denture base is lined with a silica gel pad, the sagittal intermittence vibration generated by the vibrator can accelerate the movement of orthodontic tooth; when the vibrator vertically vibrates, the initial pain of the orthodontic treatment can be relieved, or the effects of clicking the tooth is achieved; and the blenching gel is placed into the inner wall of the upper denture base and the lower denture base respectively to achieve the function of blenching the teeth.

The present invention relates to improved uses of GLP-1 peptides in oral therapy.

The invention discloses an oral disease control application method of fructus momordicae antimicrobial active ingredients, in particular to a method for making the fructus momordicae with antimicrobial active extracts prepare into drugs, food and commodities with function of oral health care and therapy, and for making the fructus momordicae with antimicrobial active extracts content in the above products reach 0.1 to 25 percent. The drugs with function of oral therapy of the invention can adopt various preparations, such as tablets, spray, powder, film agent, paint agent, ointment, gel agent and gargle agent; food and commodities with function of oral health care comprises chewing gum, beverage, tea, wine, toothpaste and dentifrice. The invention applies the extracted strong antimicrobial active ingredients from the leaves, vines, roots, stems and fruits of the ructus momordicae on human oral disease for the first time; develops drugs for controlling dental caries, periodontitis, gingivitis, toothache and hemorrhage, oral ulcer, halitosis, pharyngitis, throat pain and other diseases, food and commodities with function of oral health care. Thereby, the application method has the advantages of wide application prospect, important social benefits and economic benefits.

The invention belongs to the field of a pharmaceutical preparation, and in particular relates to a clevidipine butyrate injection. The injection comprises 0.01-10% of clevidipine butyrate, 0.1-10% of oil phase, 5-50% of phospholipid and 40-90% of organic solvent in percentage by weight. According to the invention, the clevidipine butyrate injection with good stability can be obtained, and the clevidipine butyrate can be used for lowering blood pressure during a surgery and after the surgery and when an oral therapy is not feasible or desirable. In comparison with the prior art, the clevidipine butyrate injection is always an anhydrous system in a storage process of the injection, the injection can be prepared on spot during use, thereby being capable of preventing an oxidation reaction of phospholipids and a degradation reaction of medicines, prolonging the preservation time of the preparation and improving the stability of the injection provided by the invention.

The invention relates to the field of medicines, particularly relates to a foot fumigation prescription for treating dysmenorrhea due to yang deficiency and predominant cold and aims to solve the problems that oral western medicines have big side effect and can not realize a radical cure while oral traditional Chinese medicines are poor in effect and stimulate the stomach and intestine because means for treating dysmenorrhea are mostly oral medicines. The foot fumigation prescription for treating dysmenorrhea due to yang deficiency and predominant cold comprises the following components in parts by weight: 15g of angelica, 15g of hemlock parsley, 5g of dried ginger, 5g of small fennel, 8g of Evodia rutaecarpa, 25-35g of radix astragali, 6-10g of prepared monkshood, 5-8g of cinnamon, 5g of clove, 18-22g of black paeonia, 5g of salt, 10g of rhizoma cyperi, 7g of folium artemisiae argyi, 5g of licorice root and 5g of safflower. The prescription provided by the invention can treat dysmenorrhea due to yang deficiency and predominant cold, has strong disease pertinence, belongs to a foot fumigation therapy rather than an oral therapy, adopts special medicinal components, is favorable in curative effect, and has the effects of expelling pathogenic cold from channels, activating blood circulation to dissipate blood stasis and regulating qi and blood.

The present invention provides a combination preparation which comprises: a prior-release section comprising aspirin or a pharmaceutically acceptable salt thereof as a pharmacologically active component; and a delayed-release section comprising clopidogrel, an isomer thereof or a pharmaceutically acceptable salt thereof as a pharmacologically active component. The combination preparation of the present invention exhibits a far better effect in preventing platelet aggregation than does simultaneous oral therapy or treatment with the respective single preparations, and not only can it improve the patient's drug-taking compliance by administration once a day but it can also reduce the adverse reactions which follow long-term administration of aspirin. The combination preparation of the present invention is also advantageous in that it exhibits an outstanding effect in inhibiting blood platelet aggregation despite a reduction in the amount of aspirin ingested, and in that it converts clopidogrel resistance into susceptibility and prevents serious adverse reactions caused by clopidogrel resistance and in that it can be stored over the longer term since it is stable under common storage conditions.

The invention discloses a Kazakh traditional anti-inflammatory analgesic drug radix echinopsis extract and a preparation method thereof. The drug combines traditional medicine theory 'Kazakh Medical Studies' six yuan doctrine (Allert sudden solid Seoul), and mainly has the functions of resisting inflammation, clearing away heat and toxic materials and diminishing swelling and apocenosis. The drug is an oral preparation prepared through evenly mixing part of medicinal plants of Kazakh traditional plants of compositae echinops as medicine and food after ethanol extraction, water extraction, alcohol precipitation and macroporous resin column chromatography. The drug can be prepared into all the dosage forms such as oral liquid suitable for preventing and treating inflammation in clinical. The drug disclosed by the invention particularly has good curative effect to the adjuvant oral therapy of inflammatory diseases such as epidemic parotitis, mammitis, carbuncle sore throat, joint pain and heat-toxicity bloody flux and has antiphlogistic and analgesic effects. The drug disclosed by the invention has the advantages of reasonable formula, convenience in preparation, obvious curative effect, rapid onset of action and no toxic or side effects such as irritation.

An expendable auxiliary tool for the oral therapy in order to provide a sufficient therapeutic space in oral cavity is composed of a local tooth sleeve, a supporting rod, a buccal plate and a position fixing ring for fixing and protecting tongue and fixing a saliva sucking tube.

The present invention provides a composite preparation which comprises: a prior-release section comprising aspirin or a pharmaceutically acceptable salt thereof as a pharmacologically active component; and a delayed-release section comprising clopidogrel, an isomer thereof or a pharmaceutically acceptable salt thereof as a pharmacologically active component. The composite preparation of the present invention exhibits a far better effect in preventing platelet aggregation than does simultaneous oral therapy or treatment with the respective single preparations, and not only can it improve the patient's drug-taking compliance by administration once a day but it can also reduce the adverse reactions which follow long-term administration of aspirin. The composite preparation of the present invention is also advantageous in that it exhibits an outstanding effect in inhibiting blood platelet aggregation despite a reduction in the amount of aspirin ingested, and in that it converts clopidogrel resistance into susceptibility and prevents serious adverse reactions caused by clopidogrel resistance and in that it can be stored over the longer term since it is stable under common storage conditions.

The invention discloses a mouth support device with a spit sucking function. The device comprises a support plate with an inner end facing to the inside of the mouth and an outer end facing to the outside of the mouth; the support plate has a trend of gradually becoming smaller from the outer end to the inner side; the device also comprises an upper oblique plate and a lower oblique plate which are fixed on the same side of the support plate along the trend; the upper and lower oblique plates are opposite and provided with opposite upper angular surface and lower angular surface respectively; the upper and lower angular surfaces are provided with protruding corner angles matched with the upper and lower teeth designed based on ergonomics respectively; protruding limit sides are arranged on the sides far away from the support part, of the upper and lower oblique plates, and are reversely fastened with the upper and lower teeth to prevent sliding respectively and support the oral cavity in a natural open state; the mouth support device also comprises a spit sucking tube; and the spit sucking pipe is fixed in a round through hole arranged in the middle of the support plate and used for sucking redundant spit in the mouth of people experiencing an operation. The mouth support device with the spit sucking function integrates the functions of supporting a mouth and sucking spit, and is convenient for a doctor to fix the spit sucking tube to suck spit in the oral cavity of the people experiencing an operation without adopting an external force or other auxiliary tool in oral therapy.

The invention provides lyophilized powder containing esomeprazole sodium and a preparation method thereof, and belongs to the technical field of medicines. The esomeprazole sodium is an effective drug for treating acid-related diseases like peptic ulcer and gastroesophageal reflux diseases, and a lyophilized powder preparation containing the esomeprazole sodium is an alternative preparation for treating reflux esophagitis when an oral therapy is not applicable. The lyophilized powder has the advantages of stable sample quality, less impurities, good compound solubility and low cost, and is applicable to industrial production.

The present invention relates to methods of treating or reducing the risk of necrotizing enterocolitis (NEC) in an infant comprising orally administering an effective amount of a CpG-ODN. It is based, at least in part, on the results of experiments in which orally administered CpG-ODNs were observed to reduce the histopathology and markers of inflammation in a murine model for NEC. The present invention further provides for oral formulations of CpG-ODN for administration to infants.

Methods of normalizing vitamin B12 levels in patients with low vitamin B12 and methods of normalizing intersubject variability in the treatment of such patients are described. Methods of reducing MMA and / or homocysteine levels, and pharmaceutical compositions useful to effect such changes are also described.

The invention provides a skin bacteriostatic cream and a preparation process thereof. The skin bacteriostatic cream comprises the following raw materials: radix angelicae sinensis, radix sophorae flavescentis, radix et rhizoma rhei, cortex phellodendri, fructus bruceae, cassytha filiformis, radix notoginseng, radix scutellariae, radix angelicae dahuricae, rhizoma chuanxiong, radix salviae miltiorrhizae, mirabilitum, white pearl and chlorhexidine acetate. The skin bacteriostatic cream has the beneficial effects that after the traditional Chinese medicine extract is prepared into an ointment for transdermal administration, the content of effective components of the medicine at the unit area of the epidermis can be increased, and the medicine effect is improved; meanwhile, by selecting a proper ointment type, the activity of the effective components of the traditional Chinese medicine extract can be protected, and inactivation or failure of the effective components in the long-term storage process is prevented, so that the skin bacteriostatic cream is superior to injection and oral therapy, medicine powder smearing and the like for skin diseases, can be used for various skin diseases, and is good in curative effect, quick in effect and free of side effects; and the skin bacteriostatic cream prepared by the preparation process of the skin bacteriostatic cream is good in smearing skin feeling, heat resistance, cold resistance and long-term stability.

The invention discloses a Kazakhstan medical composition for curing stagnated lung heat type diabetes mellitus and a preparation method of the Kazakhstan medical composition. The Kazakhstan medical composition combines the Six-element Theory in the Kazakh Medical Studies such as the theoretical basis of traditional medical sciences (namely Ozeg Alta Turor Theory), the Qi, Function and Energy Theory (namely Hu Wadhi Theory), the Humouralism (namely Suhler Theory), the Visceral Organ Theory (namely Wood Bisceglie Seoul Theory), and the main function of the medical composition is to prevent and cure diabetes mellitus. The traditional Kazakhstan medicines of pollen, radix Ophiopogonis, rhizoma alismatis, ginseng, coptis chinensis and lalang grass rhizome are chosen, extracted with water and ethanol, and then uniformly mixed to prepare an oral preparation. The medical composition can be any of oral preparations such as decoction, pills, powder, granules for clinically preventing and curing the diabetes mellitus. The Kazakhstan medical composition has a particularly good effect in adjuvant oral therapy of the stagnated lung heat type diabetes mellitus and the like. The Kazakhstan medical composition is reasonable in formula, convenient to prepare and remarkable in curative effect, and has no toxic or side effects such as irritation.

The invention discloses a convenient phlegm cleaner for oral therapy, wherein the convenient phlegm cleaner comprises a placement cylinder; a circular cavity is arranged at the bottom of the cylinderinterior of the placement cylinder; a fixing device is arranged at the bottom end of the cavity interior of the circular cavity; a phlegm suction cylinder is placed at the bottom of the cylinder interior of the placement cylinder, the upper end of the phlegm suction cylinder extends to the exterior of the upper part of the placement cylinder, and six U-shaped grooves distributed at equal angle arearranged on the surface of the phlegm suction cylinder; a reinforcement device is arranged at a cylinder port of the upper end of the placement cylinder. The convenient phlegm cleaner for oral therapy has the advantages of simple structure, convenient installation, disassembly and carrying, and convenient use, brings great convenience to medical staff and patients, can also hold and fix the phlegm suction cylinder by the fixing device and the reinforcement device according to needs, avoids the occurrence of phlegm reflux or sloshing splashing caused by sloshing, also avoids phlegm sloshing splashing to the trachea, avoids polluting exhaust components, reduces the workload of personnel, facilitates cleaning and disinfection, ensures the quality of phlegm suction, and improves the use efficiency of the phlegm cleaner.

The treatment of sexual dysfunction in human patients by an oral therapy regimen of administration of apomorphine and sildenafil is disclosed. This treatment optimizes the efficacy of each drug and substantially minimizes the undesirable side effects associated individually therewith. Apomorphine and sildenafil can be co-administered with a combination dosage unit or administered sequentially in separate dosage units, substantially prior to sexual activity. Other erectogenic agents can be administered along with apomorphine and sildenafil.

The present invention relates to injectable oil in water pharmaceutical composition comprising effective amount of clevidipine or a pharmaceutically acceptable salt or ester as an active agent and process of preparation thereof. The invention also relates to the use of the emulsion in intravenous administration during surgery and postoperatively in hypertension and for short term treatment of hypertension when oral therapy is not feasible or desirable.

The nattokinase is a safe high-effective enzyme preparation with fibrinolytic activity. Said invention uses the gene enginering method to implement expression of nottokinase with fabrinolytic activity. As compared with natural nattokinase, said invented recombinant product possesses excellent biological activity. The tests shw that the nattokinase possesses the excellent thrombolytic action and can accelerate production of endogeneous t-PA, so that it can directly and indirectly accelerate thrombolytic action, and at the same time, it is high in safety and easy for oral therapy.

An expendable auxiliary tool for the oral therapy in order to provide a sufficient therapeutic space in oral cavity is composed of a local tooth sleeve, a supporting rod, a buccal plate and a positionfixing ring for fixing and protecting tongue and fixing a saliva sucking tube.

The invention discloses a traditional Chinese medicine decoction for treating tubal factor infertility through acupuncture and medicine combination and a treatment method. On the basis of acupuncturegroup treatment, a traditional Chinese medicine decoction oral administration treatment method is used in a cooperative manner; in a recipe, cortex moutan, radix paeoniae rubra, rhizoma chuanxiong, rhizoma cyperi, fructus aurantia, rhizoma corydalis, peach kernel, turtle shell, earthworms, radix linderae, safflowers, spina gleditsiae, thunberg fritillary bulb and fructus liquidambaris have the effects of promoting blood circulation to remove blood stasis, regulating qi, warming meridians, eliminating stagnation, diminishing swelling, dispelling the wind, activating collaterals, resisting inflammation and alleviating pain; under the guidance by a meridian and collateral theory, according to an acupoint selection principle, nearby position acupoint selection, distant position acupuncture selection and syndrome differentiation symptomatic acupoint selection are performed; genital organs such as oviducts are positioned in the lower abdomen, so Guanyuan, Qihai and Zhongji points in Ren channel acupoints are selected; two sides of the Xuehai and Sanyinjiao acupoints in the spleen meridian of foot-Taiyin, two sides of the Guilai acupoint and the two sides of the Zusanli acupoint in the stomach meridian of foot-yangming, and two sides of the Ganshu acupoint in the bladder meridian of foot Taiyang are selected according to an acupoint combination principles of affected meridians; and the acupoints such as extra nerve points of the Zigong acupoint are selected according to symptomatic acupoint selection for treating the tubal factor infertility in an auxiliary way.

The embodiment of the present application discloses a real-time image sharing method for oral treatment in a smart medical scene. In this method, the first smart glasses are worn by a certain doctor, the second smart glasses are worn by a certain patient, and the first smart glasses pass through the The first shooting module set on the front side of the spectacle frame shoots the real-time picture of oral treatment when the doctor performs oral treatment for the patient from the perspective of the doctor, and transmits the real-time picture of oral treatment to the second smart glasses; the second smart glasses The real-time image of oral treatment transmitted by the first smart glasses is obtained, and the real-time image of oral treatment is projected onto the retina of the patient by using a harmless laser. The embodiment of the present application allows the patient to watch the real-time picture of the oral treatment performed by the doctor (such as oral root canal treatment), so that the patient can communicate with the doctor in time when he is dissatisfied with the oral treatment process performed by the doctor , which is conducive to improving patient satisfaction with dental treatment outcomes.

A collection of therapies that are useful in a speech pathology setting, the common denominator of the therapies is that they each make use of chewing gum. Chewing gum administered to a patient can be used to treat swallowing disorders and oral motor impairments. In a major aspect of the invention, a series or kit of chewing gums of varying hardness can be used to treat mastication disorders. The gum exercise program will use the varying gum hardnesses as exercises for the muscles of the mouth, mastication, oral motor, sensory / stimulation, and swallowing therapeutic interventions. The instant therapies are more functional than existing dysphagia and oral motor interventions because they are similar to masticating real food by eliciting saliva production and taste buds from the gustatory response of the lemon and sour flavors. In addition, for sensory / stimulation exercises, the varying degrees of gum hardness, along with the lemon and other flavors, provide sensory feedback.

The invention discloses an OLED oral therapeutic instrument, which comprises a shell body, an OLED light source and a power supply driving device, wherein the OLED light source is arranged at the end part inside the shell body, and is used for emitting red light. The OLED light source adopted by the OLED oral therapeutic instrument emits light uniformly, is not liable to cause adverse effect to the therapist during the therapeutic process, and can enable the size of the OLED oral therapeutic instrument to be light and thin since the OLED light source is a self-luminous light source with the advantages of having small occupied space, and being light, thin and flexible. Meanwhile, the OLED oral therapeutic instrument has the functions of portability, self-powering, automatic disinfection, data transmission and the like.

The invention provides a medical gas supply device with an active waste gas recovery system. The medical gas supply device includes a medical gas supply device body, which comprises an air supply exhausting portion, an air supply pipe, an exhaust pipe and a pipeline connector, wherein the air supply and exhaust portion is provided with a top cover, a pipeline system and a lip brim, and the air supply exhausting portion respectively communicates with the air supply pipe and the exhaust pipe. The medical gas supply device is used for performing gas supply and waste gas recovery devices for nitrous oxide sedation and anesthesia in oral therapy and surgery, and is also used in other surgical situations where nitrous oxide sedation and anesthesia are required. The medical gas supply device hasthe advantages of simple structure, compactness and small size, and is an integrated structure, which can be used for one-time use, and can provide a simple, convenient, reliable and safe gas supply device for nitrous oxide sedation and anesthesia. The medical gas supply device has the advantages of being easy to use, is hygienic and safe, does not affect a clinic room, does not hinder the surgeon's operation, can observe the entire face of the patient and facilitate communication with the patient, has low cost, and can greatly reduce the economic burden of the patient.

The invention discloses a health-care electronic cigarette liquid for medical use, which mainly comprises: 3-5%w / v of tobacco leaf extract, 40-50%m / v of propanediol, 10-15%m / v of pure water, 3-5%m / v of tobacco essence, 0.2-1.0%m / v of stabilizer, 3-8%m / v of thickener, 15-20%m / v of medicament. Because of no harm of second-hand smoke, the invention can be used at public places without influence to body health of others. The invention is capable of treating cough, hacking cough, itchy throat, abundant expectoration, sensitive cough cause by acute upper respiratory tract infection of fever, influenza or the like while enjoying smoking, having treatment function to oral therapy, cough relieving, nasal and pharyngeal mucosa congestive swelling relieving and sneezing.