31 results about "Oral rehydration salts" patented technology

The invention discloses an oral rehydration salt effervescent tablet which mainly contains sodium chloride, postassium chloride, anhydrous dextrose, citric acid, sodium bicarbonate and / or sodium carbonate and water-soluble lubricant. The invention also discloses the application of the oral rehydration salt effervescent tablet. The oral rehydration salt effervescent tablet is convenient to carry and use. The dosages of an acid source and an alkali source in the oral rehydration salt effervescent tablet can reflect the dosage of sodium citrate needed by the prescription for producing oral rehydration salt (ORSII), thereby reducing the addition of the raw material sodium citrate and lowering the production cost effectively.

An orally-applied flash-dissolving tablet for supplementing salt to human body is prepared from sodium chloride, sodium citrate, potassium chloride, anhydrous glucose, cane sugar, sorbitol, xylitol, tween-80, citric acid and superfine silica gel powder. Its preparing process is also disclosed.

The invention provides drug composition of oral rehydration salt and a preparation method of the drug composition. The composition comprises main components including sodium chloride, potassium chloride or potassium citrate, sodium citrate, zinc gluconate, albumin tannate and anhydrous glucose. The drug composition of oral rehydration salt can be used for protecting and repairing intestinal mucosa, promoting regeneration of intestinal epithelial cells and reducing secretion of water and electrolyte by the intestinal mucosa, exudation is reduced, and stimulation and intestine peristalsis are relieved.

The invention provides a liquid oral rehydration salt which comprises the following components in percentage by weight: 0.056-0.96% of sodium chloride, 0.034-0.042% of potassium chloride, 0.065-0.079% of sodium citrate, 0.31-0.37% of glucose and 94.5-104.5% of water. The liquid oral rehydration salt is used for treating mild and moderate dehydration caused by diarrhea and dehydration caused by children diarrhea. Through accurate control of water dosage, asepsis operation and other treatment, the high liquid oral rehydration salt is stable in quality, more convenient to use and suitable for being taken by old people and children under water shortage conditions in the open air and in case of an emergency, and can better express the efficacy.

The invention discloses a preparation method of a low-permeability oral rehydration salt. The low-permeability oral rehydration salt comprises sodium chloride, potassium chloride, sodium citrate and glucosum anhydricum, wherein the granularity of the powder passing through a 100mesh sieve is greater than or equal to 95%. The preparation method is characterized by comprising the following steps: 1) respectively weighing prescription amount of sodium chloride, potassium chloride, sodium citrate and glucosum anhydricum for late use; 2) respectively taking a certain amount of one or more of glucosum anhydricum, sodium chloride, potassium chloride and sodium citrate to combine and crush in common, and filtering by the 100mesh sieve; 3) crushing the residual glucosum anhydricum and filtering by the 100mesh sieve; 4) evenly mixing the mixture in the step 2) with the glucosum anhydricum in the step 3) inside a mixer, and split charging. By adopting the preparation method, the problem that the sodium chloride, the potassium chloride and the sodium citrate are easily blocked after being crushed into fine powder is effectively solved; no agglomerate phenomenon is generated in the overall mixing process; the mixing process is quick and smooth; the mixing uniformity and the granularity achieve the requirements of Chinese pharmacopoeia 2010 version.

An orally-applied ffervescent tablet for supplementing salt to human body is prepared from sodium chloride, sodium citrate, potassium chloride, anhydrous glucose, dicarbonate, and pregelatinized starch through baking pregelatinized starch anddicarbonate, sieving others, proportional mixing, andtabletting.

The invention discloses glucose electrolyte effervescent tablets and a preparation method for the glucose electrolyte effervescent tablets. By adopting a polyethylene glycol coating technology, the method is easy and convenient to operate, shortens the production procedure, and is short in production period, safe, easy to control and low in production cost; and the prepared tablets overcome the defect of high osmotic pressure of the conventional oral rehydration salts, improve the taste, can effectively prevent a condition that the oral rehydration salts are rejected due to poor mouthfeel, and are suitable for children.

The invention discloses a preparation method for novel corrective flavor type oral rehydration salt powders. Active ingredients comprise potassium chloride, sodium chloride, sodium citrate and dextrose anhydrous, and essence is added as an auxiliary material. The essence is added by using a spraying method, a method of adsorbing the essence by a superfine silica powder, a method of microencapsulating the essence to obtain an essence powder with beta-cyclodextrin as a wall material, or a polyvinylpyrrolidone (PVP-K30) copolymer method, and the essence is evenly mixed with the active ingredients for subpackage to obtain the oral rehydration salt powders. Based on a conventional oral rehydration salt, the essences with different flavors are added by different ways, and the oral rehydration salt powders with the different flavors are prepared; the oral rehydration salt powders improve conventional poor taste, are easy to take and especially easy to take for children, and improve the medical compliance.

An orally-applied dispersing tablet for supplementing salt to human body is prepared from sodium chloride, sodium citrate, potassium chloride, anhydrous glucose, dicarbonate, pregelatinized starch, polyvinyl pyrrolidone, meganesium stearate, and cross-linking carboxymethyl cellulose sodium. Its preparing process is also disclosed.

The invention discloses a pyruvate oral rehydration salt composition for curing circulation hypovolemia or water-losing with salt-losing. The composition comprises the following components: (i) 2.0-6.0 parts by weight of sodium pyruvate, (ii) 1.5-17.0 parts by weight of sodium chloride, (iii) 0-2.0 parts by weight of potassium chloride, and (iv) 10.0-50.0 parts by weight of anhydrous glucose or other carbohydrates; and the sum weight of the components (i), (ii), (iii), and (iv) is 50-100 % of the total composition weight.

The invention discloses a long-distance transport stress reaction preparation for ruminants. The preparation comprises a first preparation composition and a second preparation composition, wherein the first preparation composition comprises the following components: astragalus polysaccharides, artificial oral rehydration salt, complex vitamins and peony root powder; and the second preparation composition comprises the following components in parts by mass: bacillus subtilis strains and saccharomycetes strains. According to the long-distance transport stress reaction preparation for ruminants and the using method thereof disclosed by the invention, the fatality rate of the ruminants due to stress reaction in the long-distance transport process is greatly reduced, the death rate of sheep is reduced from 30 percent to less than 5 percent in the transport process of 2-5 days, and the death rate of cattle is reduced from 10 percent to less than 5 percent.

The invention discloses a preparation method of a low-permeability oral rehydration salt. The low-permeability oral rehydration salt comprises sodium chloride, potassium chloride, sodium citrate and glucosum anhydricum, wherein the granularity of the powder passing through a 100mesh sieve is greater than or equal to 95%. The preparation method is characterized by comprising the following steps: 1) respectively weighing prescription amount of sodium chloride, potassium chloride, sodium citrate and glucosum anhydricum for late use; 2) respectively taking a certain amount of one or more of glucosum anhydricum, sodium chloride, potassium chloride and sodium citrate to combine and crush in common, and filtering by the 100mesh sieve; 3) crushing the residual glucosum anhydricum and filtering by the 100mesh sieve; 4) evenly mixing the mixture in the step 2) with the glucosum anhydricum in the step 3) inside a mixer, and split charging. By adopting the preparation method, the problem that the sodium chloride, the potassium chloride and the sodium citrate are easily blocked after being crushed into fine powder is effectively solved; no agglomerate phenomenon is generated in the overall mixing process; the mixing process is quick and smooth; the mixing uniformity and the granularity achieve the requirements of Chinese pharmacopoeia 2010 version.

The invention discloses an oral rehydration salt effervescent tablet and a preparation method thereof. Sodium chloride, potassium chloride, citric acid and anhydrous glucose are used as main active components; sodium bicarbonate, pregelatinized starch, Tween 80 and aspartame are used as auxiliary materials. The oral rehydration salt effervescent tablet is prepared from the following components inpercentage by weight: 5% to 10% of sodium chloride, 2% to 6% of potassium chloride, 3% to 5% of citric acid, 30% to 50% of anhydrous glucose, 2% to 10% of sodium bicarbonate, 6% to 12% of pregelatinized starch, 0.2 to 0.4% of Tween 80 and 0.1 to 0.3% of aspartame. The oral rehydration salt effervescent tablet has the advantages that the effervescent tablet can produce carbon dioxide in water, so that the medicine tablet is quickly disintegrated into small fragments, and the medical components are quickly dissolved; the symptoms of acute and severe patients requiring the medicines to quickly take effect can be timely treated and relieved; the effervescent tablet is especially suitable for the children, the old people and the patients difficulty in taking of pills; the carrying and use are convenient, and the appearance is clear.

The invention discloses an electrolyte solid beverage, and belongs to the technical field of food processing. The electrolyte solid beverage has two functions of supplementing body fluid and improvingintestinal tract environments, the electrolyte solid beverage can be used for relieving a diarrhea symptom and a dehydrating symptom generated after fever and diarrhea of children, 100g of electrolyte solid beverage is brewed by 1L of water with the temperature of 30 DEG C to obtain an electrolyte beverage, the concentrations of sodium ions, potassium ions and the like in the electrolyte beveragemeet standard concentration of third-generation oral rehydration salt recommend by the world health organization (WHO) and the united nations international children's emergency fund (UNICE), diarrheaand dehydration of 80% of children are avoided after the electrolyte solid beverage is used for 8 hours, and diarrhea and dehydration of almost all children are avoided after the electrolyte solid beverage is used for 12 hours.

The invention relates to an oral-taking rehydration salt, which is prepared from the following raw materials in parts by weight: 0.4 to 0.9 part of sodium chloride, 0.5 to 1 part of sodium citrate, 0.2 to 0.6 part of potassium chloride, 2-5 parts of anhydrous dextrose, 0.2 to 1 part of fruit powder, and 0.02 to 0.5 part of a compound additive, wherein the compound additive is prepared by mixing zinc gluconate and bifidobacterium animalis Bb-12. The oral-taking rehydration salt disclosed by the invention has good curative effect on infantile diarrhea.

The invention relates to a novel oral rehydration salts solution. The novel oral rehydration salts solution comprises the following components: sodium chloride, sodium citrate, carboxymethyl cellulose sodium, sodium potassium tartrate tetrahydrate, potassium chloride, zinc acetate, zinc chloride, glucosum anhydricum and deionized water. According to the novel oral rehydration salts solution and the preparation method and use thereof, the novel oral rehydration salts solution has excellent curative property and high diarrhea curative rate through selection of the specific components, limit to the content of specific ions and the specific preparation method, and a good application prospect and industrial production potential in the field of medicine are achieved.

The invention discloses oral rehydration salt and a preparation method thereof. Every 1,000ml of the oral rehydration salt comprises the following components by mmol: 79-81mmol of sodium chloride, 2.2-2.4mmol of sodium citrate, 2.2-5.6mmol of potassium chloride, 2.1-3.2mmol of zinc chloride, 60-80mmol of anhydrous glucose, 91-110mmol of deionized water, 1-2mmol of a pH regulator, wherein the content of total sodium (Na<+>) is 83-94mmol / L, the content of total chlorine (Cl<->) is 82-95mmol / L and the content of total potassium (K<+>) is 4.2-8.9mmol / L of; and the pH value of the oral rehydrationsalt is 6.2-6.4. According to the oral rehydration salt and the preparation method, the pH regulator is dropwise added for enabling the pH value to be 6.2-6.4 while the anhydrous glucose is added intothe deionized water, so that the anhydrous glucose is enabled to be in a liquid with the pH value of 6.2-6.4 all the time, the anhydrous glucose is guaranteed to be almost not degraded, an obtained product is stable, and a treatment effect is relatively good.

The invention relates to an oral rehydration salt, which comprises the following components: sodium chloride, sodium citrate, sodium hydroxymethylcellulose, potassium sodium tartrate, potassium chloride, zinc acetate, zinc chloride, Anhydrous dextrose and deionized water. The oral rehydration salt has excellent therapeutic properties through the selection of specific components, the content limitation of specific ions, and a specific preparation method, etc., and has an excellent cure rate of diarrhea, so it has a good reputation in the field of medicine. Application prospects and industrial production potential.

Disclosed in the present invention is a sodium pyruvate oral rehydration salt composition for treating hypovolemia or hyponatration associated with hypohydration, said composition containing the following components: (i) 2.0-6.0 parts by weight of sodium pyruvate; (ii) 1.5-17.0 parts by weight of sodium chloride; (iii) 0-2.0 parts by weight of potassium chloride; and (iv) 10.0-50.0 parts by weight of glucose anhydrous or other carbohydrates. The weight of components (i)+(ii)+(iii)+(iv) constitutes 50-100% of the total weight of the composition.

The present invention discloses oral supplement fluid salt powder and a preparation method thereof. The oral supplement fluid salt powder is composed of sodium chloride, potassium chloride, sodium citrate and anhydrous glucose. The preparation method is composed of a pulverizing step, a mixing step and a sub-packaging step; the pulverizing step is respectively pulverizing sodium chloride, potassium chloride and sodium citrate; and the mixing step is putting anhydrous glucose within half of a prescription amount into a mixer, adding the prescription amount of the sodium chloride, potassium chloride and sodium citrate, starting the mixer to start mixing, and taking out the drug powder after mixing to conduct sieving and dispersing; and adding the sieved powder to the mixer, adding the remaining anhydrous glucose, and starting the machine again to complete mixing. The preparation method reduces content of sodium and glucose, thus lowers osmotic pressure, and is more suitable for dehydration prevention of infants and young children and fluid supplement of mild to moderate dehydration without circulation failure.

The invention relates to a medicine composition of oral rehydration salt, which also can be called oral rehydration salt powder III in some embodiments. Specifically, the medicine composition of oral rehydration salt comprises potassium chloride, sodium chloride, sodium citrate and glucose. More specifically, the oral rehydration salt powder comprises 1 part of potassium chloride, 1.3-2.5 parts of sodium chloride, 1.5-2.5 parts of sodium citrate and 6-15 parts of glucose by weight. The oral rehydration salt powder provided by the invention has the characteristics that the preparation technology is simple, the process control is easy, the phenomena of crystallization and clustering are avoided in the preparation process, the product dissolution speed is high, and the like. The oral rehydration salt powder provided by the invention obviously overcomes some important technical problems often caused by the common powder, can provide an oral rehydration salt preparation with good pharmaceutical performance for clinical use, has significant innovation, and is certainly to bring tremendous social and economic benefits.

The invention discloses a roaster nutritional supplement and a producing method thereof.The roaster nutritional supplement is mainly prepared by mixing, by weight, 60-80 parts of rice cake powder, 15-35 parts of glucose, 3-8 parts of oral rehydration salts, 1-3 parts of milk powder and 0.1-0.3 part of sodium benzoate.The rice cake powder is made by smashing rice into 60-100 mesh and conducting cooking and drying.The roaster nutritional supplement is obtained by stirring and mixing the components sufficiently.The roaster nutritional supplement can be used by adding boiled water of 5-15 folds and sufficiently and evenly stirring the materials.The product can be used for feeding various pigs suffering from diseases and malnutrition, especially for supplementing nutrients to roasters suffering from lack of milk or diseases, dehydration and malnutrition of roasters can be effectively prevented, culture effect is remarkable, manufacturing process is simple, energy and time are saved, and industrial production is easy.

The invention discloses an effervescent preparation of compound oral rehydration salt as well as a preparation process and application of the effervescent preparation. The effervescent preparation comprises the following components in percentage by mass: 30-90% of a main medicine composition of rehydration salt, probiotics and modified montmorillonite coated particles and 10-70% of pharmaceutically acceptable effervescent auxiliary materials; and wherein the content of the probiotics is 10 < 6 >-10 < 10 > CFU / g, and the effervescent auxiliary materials comprise an acid source and an alkali source. According to the effervescent preparation of the compound oral rehydration salt, the rehydration salt, the probiotics and the modified montmorillonite coating particles are combined for use, and after the rehydration salt and the probiotics exert corresponding curative effects after orally taking the effervescent preparation, montmorillonite generates mucous membrane attachment, a continuous protection effect on gastrointestinal tracts is achieved, and the side effects caused by combined administration of rehydration salt, montmorillonite and other medicinal preparations are effectively overcome. The effervescent preparation can be used for effectively treating and relieving symptoms of urgent and severe patients needing the medicine to take effect quickly in time, is also particularly suitable for children, old people and patients who are difficult to take pills, and is convenient to carry and use.

The invention relates to oral rehydration salt used for rapidly supplementing piglets for fluid, and belongs to the technical field of veterinary medicines. The oral rehydration salt is composed of a plurality of electrolytes and a plurality of glucoses. The oral rehydration salt is suitable for rapidly supplementing the piglets for the body fluid after the piglets scour, and death caused by dehydration is prevented.

The invention relates to an oral rehydration salt effervescent tablet for animals. The effervescent tablet mainly consists of the following components: 180-200g of sodium bicarbonate, 130-150g of citric acid, 80-100g of sodium carbonate, 40-50g of potassium chloride, 30g of potato powder, and lactose which is added until the total weight is 1000g. The effervescent tablet has the advantages that: the dissolution rate of medicines is increased by adopting the effervescent tablet dosage form, the distribution of the medicine molecules on the intestinal tract surface is facilitated, and the bioavailability of the medicines is increased. Nutrients and anti-diarrhea factors are added, so that the effervescent tablet can perform fluid infusion and lighten the injury of intestinal mucosa, and hasthe function of repairing the intestinal mucosa. The product has the advantage of isotonic ratio, the scientific isotonic ratio better accords with the ion trend of animals, the dehydration problem caused by diarrhea can be solved by oral administration, the problems that the supplement dosage of original products is difficult to master, the relative ratio is simple, and the treatment effect cannot be achieved are solved, the product is more convenient to use for consumers, and the effect is more obvious.

The invention relates to a method for making an ascending aortic aneurysm animal model. The method comprises the following steps: (1) ligating the root of the ascending aorta of a mouse by using a cushion needle with the outer diameter of 1.0-1.6 mm; (2) feeding the mouse undergoing a ligation operation with an oral rehydration salt solution containing tramadol hydrochloride capsules. The making method is simple and feasible, can be widely applied and popularized, and is high in tumor forming rate and short in tumor forming time.

The invention discloses oral rehydration salt. The oral rehydration salt comprises 20-60 mM of sodium ions, 5-20 mM of potassium ions, 20-50 mM of chloride ions, 75-190 mM of glucose, 0-10 mM of calcium ions, 0-5 mM of magnesium ions, 0-10 mM of bicarbonate ions, and 2-10 mM of citrate ions. A preparation method of the oral rehydration salt comprises the following steps of: S1, respectively weighing the components including sodium chloride, potassium chloride, magnesium citrate, sodium citrate and calcium bicarbonate; S2, grinding the components, and filtering to ensure that the particle sizeof each component is 130-160 meshes; and S3, mixing the components, adding a dark berry extract, uniformly mixing, and packaging. The oral rehydration salt is suitable for Chinese physique, can quickly and effectively supplement water and electrolyte lost in the body under different mild and moderate dehydration conditions, can supplement several ions essential for the human body, and ensures thenormal electrolyte.

The invention provides a liquid oral rehydration salt which comprises the following components in percentage by weight: 0.056-0.96% of sodium chloride, 0.034-0.042% of potassium chloride, 0.065-0.079% of sodium citrate, 0.31-0.37% of glucose and 94.5-104.5% of water. The liquid oral rehydration salt is used for treating mild and moderate dehydration caused by diarrhea and dehydration caused by children diarrhea. Through accurate control of water dosage, asepsis operation and other treatment, the high liquid oral rehydration salt is stable in quality, more convenient to use and suitable for being taken by old people and children under water shortage conditions in the open air and in case of an emergency, and can better express the efficacy.

The invention discloses an oral rehydration salt effervescent tablet which mainly contains sodium chloride, postassium chloride, anhydrous dextrose, citric acid, sodium bicarbonate and / or sodium carbonate and water-soluble lubricant. The invention also discloses the application of the oral rehydration salt effervescent tablet. The oral rehydration salt effervescent tablet is convenient to carry and use. The dosages of an acid source and an alkali source in the oral rehydration salt effervescent tablet can reflect the dosage of sodium citrate needed by the prescription for producing oral rehydration salt (ORSII), thereby reducing the addition of the raw material sodium citrate and lowering the production cost effectively.

The invention discloses a preparation method of an oral rehydration salts effervescent tablet, relates to the technical field of medicines, and aims to solve a technical problem that an existing oralrehydration salts effervescent tablet is easy to stick and poor in stability. The preparation method comprises the following steps: 1, crushing sodium chloride, potassium chloride, citric acid, sodiumbicarbonate and anhydrous dextrose to 60-80 meshes; 2, weighing raw materials and auxiliary materials according to prescription amounts for later use; 3, preparing a 20% K30-pigment solution by usingan 80% ethanol aqueous solution; 4, putting sodium chloride, potassium chloride, sodium bicarbonate and 60-80% of anhydrous dextrose into a wet granulator, pouring a part of the K30-pigment solution,granulating, drying and straightening; 5, pouring citric acid, the residual anhydrous dextrose and a part of lactose into the wet granulator, pouring the residual K30-pigment solution, granulating, drying and straightening; and 6, totally mixing the particles obtained in the steps 4 and 5 with other materials, and tabletting. The effervescent tablet increases patient compliance. The preparation method improves stability of the effervescent tablet.