The invention provides an anti-wrinkle eye cream, wherein natural marine conotoxin is rich in various amino acids, the combined action of the natural marine conotoxin and dipeptide diaminobutyroyl benzylamide diacetate can improve ocular microcirculation and alleviate dark eye circles, and inhibit contraction of ocular muscles, thereby achieving the effect of reducing wrinkles; by jointing using hydrolyzed wheat protein, hydrolyzed collagen and hydrolyzed soybean protein, and utilizing compounding of the collagen, a moisturizing protective film is formed on a skin surface, so as to enhance theadherence of matrix outside epithelial cells, maintain a compact state of epithelial lipid monolayer molecular film, increase the level of cellular protein, and promote the synthesis of the collagen,thereby synergistically enhancing the anti-wrinkle effect; and ceramide, tocopherol acetate and saccharomyces lysate promote the skin metabolism, prevent pigment deposition, improve skin elasticity,lock moisture in the skin, repair skin barriers, and moisten the skin.