83 results about "Allylic alcohol" patented technology

The present invention relates to new compositions and reactions to produce allylic alcohols or precursors of allylic alcohols (e.g., silyl ethers of allylic alcohols). Methods of the invention may comprise combining an alkene and an aldehyde in the presence of a transition metal catalyst (e.g., a nickel catalyst) to form an allylic alcohol or precursor of an allylic alcohol. Reaction products of the present invention may be valuable as intermediates and / or products in pharmaceutical and polymer research. Also, methods of the invention may be useful as fragment coupling reactions in complex molecule synthesis. Moreover, methods of the invention may include the use of reagents which, under reaction conditions known in the art, may have been unreactive, i.e., may not have been able to form the reaction product. The reagents used in the present invention may be relatively lower in cost than in other methods. Also, methods of the invention may reduce the number of synthetic and purification steps required to produce the reaction products, as well as reducing time, cost, and waste production.

The present invention relates to new compositions and reactions to produce allylic alcohols or precursors of allylic alcohols (e.g., silyl ethers of allylic alcohols). Methods of the invention may comprise combining an alkene and an aldehyde in the presence of a transition metal catalyst (e.g., a nickel catalyst) to form an allylic alcohol or precursor of an allylic alcohol. Reaction products of the present invention may be valuable as intermediates and / or products in pharmaceutical and polymer research. Also, methods of the invention may be useful as fragment coupling reactions in complex molecule synthesis. Moreover, methods of the invention may include the use of reagents which, under reaction conditions known in the art, may have been unreactive, i.e., may not have been able to form the reaction product. The reagents used in the present invention may be relatively lower in cost than in other methods. Also, methods of the invention may reduce the number of synthetic and purification steps required to produce the reaction products, as well as reducing time, cost, and waste production.

The present invention relates to processes for epimerising alcohols of compounds having a hydroxyl substituent on an asymmetric allylic carbon, such as compounds useful for the synthesis of vitamin D analogues where the epimeric hydroxyl substituent is at the 24 position. The invention further relates to methods of producing intermediates useful for the synthesis of calcipotriol by said epimerisation processes.

The invention provides a method for continuously preparing linalool from allylic alcohol by an isomerization process. The method comprises the following steps: preparing a vanadium-amine complex catalyst, adding a reacting product and a catalyst, controlling isomerization reaction conditions, constantly adding the reacting product, and constantly rectifying, wherein the vanadium-amine complex catalyst is prepared by adding 1 part by weight of xylene, 0.01-0.1 part by weight of a vanadium compound and 0.01-0.1 part by weight of nitrogen base, starting to stir and heat, insulating for 1-3 hours at 140 DEG C, cooling to below 50 DEG C, and filtering to reclaim the catalyst. According to the method, the catalyst system has high reaction selectivity, the selectivity of linalool is 93.2-96.2 percent, the yield of linalool is 92.7-94.5 percent, the scrap rate is 2.7-4.0 percent, and the linalool content is 98.5-98.7 percent. The catalyst has low unit consumption.

A single-site catalyst is disclosed. The catalyst comprises a transition metal complex, an activator, and an allylic alcohol-containing polymer. The catalyst has high activity and great capability to incorporate higher α-olefins into polyethylene. The polyethylene produced has high molecular weight and low density.

The invention relates to a preparation method of an inflammation-response guided tissue regeneration membrane, which belongs to the field of the surface modification of materials. An anti-inflammation drug with hydroxyl is bonded to the surface of a membrane by adopting an ester bond, carry out selective enzymolysis on the ester bond by utilizing cholesterol esterase concentrated released by macrophage when the inflammation occurs, and a responsive release effect is achieved. The method comprises the following steps: initiating by virtue of ultraviolet rays, and introducing ITXSP (isopropylthioxanthone semipinacol) into the surface of the membrane; simultaneously adding an initiator, a cross-linking agent and an allylic alcohol monomer into the activated ITXSP surface to form a hydrogel layer; enabling the drug to react with the allylic alcohol monomer to form a drug molecule containing an ester group and carbon-carbon double bond; and finally thermally initiating the drug molecule, the allylic alcohol monomer and the cross-linking agent, loading a gel layer containing the drug, wherein the drug is fixed in the membrane surface gel layer by virtue of the ester group. The inflammation-response membrane has the characteristics of excellent biological compatibility and inflammation-response drug release.

A new method for preparing lithium phosphate catalysts is disclosed. The method comprises precipitating a lithium phosphate from a mixture comprising a first aqueous solution which contains lithium and sodium ions and a second aqueous solution which contains phosphate and borate ions. The resultant lithium phosphate catalyst has increased activity and selectivity in the isomerization of an alkylene oxide to the corresponding allylic alcohol.

A process for producing allylic ether compounds in presence of a catalyst comprising at least one Cu(II) salt by reaction of an allylic alcohol with either itself or another alcohol.